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2022

Journal Article

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

Tran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

2022

Journal Article

Cancer vaccines

Schiller, John T., Lowy, Douglas R., Frazer, Ian H., Finn, Olivera J., Vilar, Eduardo, Lyerly, H. Kim, Gnjatic, Sacha, Zaidi, Neeha, Ott, Patrick A., Balachandran, Vinod P., Dietrich, Pierre-Yves, Migliorini, Denis, Vonderheide, Robert H. and Domchek, Susan M. (2022). Cancer vaccines. Cancer Cell, 40 (6), 559-564. doi: 10.1016/j.ccell.2022.05.015

Cancer vaccines

2022

Journal Article

Skin cancer-associated S. aureus strains can induce DNA damage in human keratinocytes by downregulating DNA repair and promoting oxidative stress

Krueger, Annika, Mohamed, Ahmed, Kolka, Cathryn M., Stoll, Thomas, Zaugg, Julian, Linedale, Richard, Morrison, Mark, Soyer, H. Peter, Hugenholtz, Philip, Frazer, Ian H. and Hill, Michelle M. (2022). Skin cancer-associated S. aureus strains can induce DNA damage in human keratinocytes by downregulating DNA repair and promoting oxidative stress. Cancers, 14 (9) 2143, 2143. doi: 10.3390/cancers14092143

Skin cancer-associated S. aureus strains can induce DNA damage in human keratinocytes by downregulating DNA repair and promoting oxidative stress

2022

Journal Article

Analysis of human leukocyte antigen associations in human papillomavirus–positive and –negative head and neck cancer: Comparison with cervical cancer

Ekanayake Weeramange, Chameera, Shu, Danhua, Tang, Kai Dun, Batra, Jyotsna, Ladwa, Rahul, Kenny, Lizbeth, Vasani, Sarju, Frazer, Ian H., Dolcetti, Riccardo, Ellis, Jonathan J., Sturm, Richard A., Leo, Paul and Punyadeera, Chamindie (2022). Analysis of human leukocyte antigen associations in human papillomavirus–positive and –negative head and neck cancer: Comparison with cervical cancer. Cancer, 128 (10), 1937-1947. doi: 10.1002/cncr.34148

Analysis of human leukocyte antigen associations in human papillomavirus–positive and –negative head and neck cancer: Comparison with cervical cancer

2022

Journal Article

Changes in the skin microbiome associated with squamous cell carcinoma in transplant recipients

Krueger, Annika, Zaugg, Julian, Lachner, Nancy, Bialasiewicz, Seweryn, Lin, Lynlee L., Gabizon, Sharon, Sobarun, Priyamvada, Morrison, Mark, Soyer, H. Peter, Hugenholtz, Philip and Frazer, Ian H. (2022). Changes in the skin microbiome associated with squamous cell carcinoma in transplant recipients. ISME Communications, 2 (1) 13, 13. doi: 10.1038/s43705-022-00095-7

Changes in the skin microbiome associated with squamous cell carcinoma in transplant recipients

2022

Journal Article

Secreted toxins from Staphylococcus aureus strains isolated from keratinocyte skin cancers mediate pro-tumorigenic inflammatory responses in the skin

Krueger, Annika, Zaugg, Julian, Chisholm, Sarah, Linedale, Richard, Lachner, Nancy, Teoh, Siok Min, Tuong, Zewen K., Lukowski, Samuel W., Morrison, Mark, Soyer, H. Peter, Hugenholtz, Philip, Hill, Michelle M. and Frazer, Ian H. (2022). Secreted toxins from Staphylococcus aureus strains isolated from keratinocyte skin cancers mediate pro-tumorigenic inflammatory responses in the skin. Frontiers in Microbiology, 12 789042, 789042. doi: 10.3389/fmicb.2021.789042

Secreted toxins from Staphylococcus aureus strains isolated from keratinocyte skin cancers mediate pro-tumorigenic inflammatory responses in the skin

2022

Journal Article

Single-dose HPV vaccine immunity: is there a role for non-neutralizing antibodies?

Quang, Chau, Chung, Amy W., Frazer, Ian H., Toh, Zheng Quan and Licciardi, Paul V. (2022). Single-dose HPV vaccine immunity: is there a role for non-neutralizing antibodies?. Trends in Immunology, 43 (10), 815-825. doi: 10.1016/j.it.2022.07.011

Single-dose HPV vaccine immunity: is there a role for non-neutralizing antibodies?

2021

Journal Article

Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq

Rødahl, Inga, Gotley, James, Andersen, Stacey B., Yu, Meihua, Mehdi, Ahmed M., Christ, Angelika N., Hamilton-Williams, Emma E., Frazer, Ian H., Lukowski, Samuel W. and Chandra, Janin (2021). Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq. STAR Protocols, 2 (4) 100842, 1-27. doi: 10.1016/j.xpro.2021.100842

Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq

2021

Journal Article

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

Tuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E. and Frazer, Ian H. (2021). A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience, 24 (11) 103326, 103326. doi: 10.1016/j.isci.2021.103326

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

2021

Journal Article

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

Begley, C. Glenn, Ashton, Mark, Baell, Jonathan, Bettess, Michael, Brown, Michael P., Carter, Brett, Charman, William N., Davis, Christopher, Fisher, Simon, Frazer, Ian, Gautam, Anand, Jennings, Michael P., Kearney, Philip, Keeffe, Eloise, Kelly, Darren, Lopez, Angel F., McGuckin, Michael, Parker, Michael W., Rayner, Craig, Roberts, Brett, Rush, James S. and Sullivan, Mark (2021). Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers. Science Translational Medicine, 13 (612) eabd5524, eabd5524. doi: 10.1126/scitranslmed.abd5524

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

2021

Journal Article

Intratumoral injection of caerin 1.1 and 1.9 peptides increases the efficacy of vaccinated TC‐1 tumor‐bearing mice with PD‐1 blockade by modulating macrophage heterogeneity and the activation of CD8+ T cells in the tumor microenvironment

Ni, Guoying, Yang, Xiaodan, Li, Junjie, Wu, Xiaolian, Liu, Ying, Li, Hejie, Chen, Shu, Fogarty, Conor E., Frazer, Ian H., Chen, Guoqiang, Liu, Xiaosong and Wang, Tianfang (2021). Intratumoral injection of caerin 1.1 and 1.9 peptides increases the efficacy of vaccinated TC‐1 tumor‐bearing mice with PD‐1 blockade by modulating macrophage heterogeneity and the activation of CD8+ T cells in the tumor microenvironment. Clinical and Translational Immunology, 10 (8) e1335, 1-25. doi: 10.1002/cti2.1335

Intratumoral injection of caerin 1.1 and 1.9 peptides increases the efficacy of vaccinated TC‐1 tumor‐bearing mice with PD‐1 blockade by modulating macrophage heterogeneity and the activation of CD8+ T cells in the tumor microenvironment

2021

Journal Article

Salivary high-risk human papillomavirus DNA as a biomarker for human papillomavirus–driven head and neck cancers

Ekanayake Weeramange, Chameera, Liu, Zhen, Hartel, Gunter, Li, Yinan, Vasani, Sarju, Langton-Lockton, Julian, Kenny, Lizbeth, Morris, Luc, Frazer, Ian, Tang, Kai Dun and Punyadeera, Chamindie (2021). Salivary high-risk human papillomavirus DNA as a biomarker for human papillomavirus–driven head and neck cancers. The Journal of Molecular Diagnostics, 23 (10), 1334-1342. doi: 10.1016/j.jmoldx.2021.07.005

Salivary high-risk human papillomavirus DNA as a biomarker for human papillomavirus–driven head and neck cancers

2021

Journal Article

The Australian Academy of Health and Medical Sciences: an authoritative, independent voice in the Australian landscape

Scheffer, Ingrid E. and Frazer, Ian H. (2021). The Australian Academy of Health and Medical Sciences: an authoritative, independent voice in the Australian landscape. Medical Journal of Australia, 214 (11), 502-504.e1. doi: 10.5694/mja2.51089

The Australian Academy of Health and Medical Sciences: an authoritative, independent voice in the Australian landscape

2021

Journal Article

Evolution of cancer vaccines—challenges, achievements and future directions

Tay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535

Evolution of cancer vaccines—challenges, achievements and future directions

2021

Journal Article

IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression

Zeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131

IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression

2021

Journal Article

Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration

Bastow, Cameron R., Bunting, Mark D., Kara, Ervin E., McKenzie, Duncan R., Caon, Adriana, Devi, Sapna, Tolley, Lynn, Mueller, Scott N., Frazer, Ian H., Harvey, Natasha, Condina, Mark R., Young, Clifford, Hoffmann, Peter, McColl, Shaun R. and Comerford, Iain (2021). Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration. Proceedings of the National Academy of Sciences, 118 (17) e2025763118, 1-9. doi: 10.1073/pnas.2025763118

Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration

2021

Journal Article

Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells

Lukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402

Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells

2021

Journal Article

An update on cervical cancer screening in Vanuatu

Allanson, Emma R., Velanova, Vera, Frazer, Ian H. and McAdam, Margaret (2021). An update on cervical cancer screening in Vanuatu. International Journal of Gynecological Cancer, 31 (4), 631-632. doi: 10.1136/ijgc-2020-002129

An update on cervical cancer screening in Vanuatu

2021

Journal Article

Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients

Budhwani, Megha, Turrell, Gavin, Yu, Meihua, Frazer, Ian H., Mehdi, Ahmed M. and Chandra, Janin (2021). Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients. Frontiers in Molecular Biosciences, 8 622643, 622643. doi: 10.3389/fmolb.2021.622643

Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients

2021

Journal Article

Editorial: Immunology of HPV infection and vaccination: progress and challenges

Licciardi, Paul V., Frazer, Ian H., Garland, Suzanne M. and Mulholland, Kim (2021). Editorial: Immunology of HPV infection and vaccination: progress and challenges. Frontiers in Immunology, 12 665463, 665463. doi: 10.3389/fimmu.2021.665463

Editorial: Immunology of HPV infection and vaccination: progress and challenges