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2016 Journal Article A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injuryZhussupbekova, Samal, Sinha, Rohit, Kuo, Paula, Lambert, Paul F., Frazer, Ian H. and Tuong, Zewen K. (2016). A mouse model of hyperproliferative human epithelium validated by keratin profiling ahows an aberrant cytoskeletal response to injury. Ebiomedicine, 9, 314-323. doi: 10.1016/j.ebiom.2016.06.011 |
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2016 Journal Article Role of ultraviolet radiation in papillomavirus-induced diseaseUberoi, Aayushi, Yoshida, Satoshi, Frazer, Ian H., Pitot, Henry C. and Lambert, Paul F. (2016). Role of ultraviolet radiation in papillomavirus-induced disease. PLoS Pathogens, 12 (5) e1005664, e1005664. doi: 10.1371/journal.ppat.1005664 |
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2016 Journal Article Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacityChandra, Janin, Miao, Yan, Romoff, Natasha and Frazer, Ian H. (2016). Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity. Plos One, 11 (3) e0152886, e0152886. doi: 10.1371/journal.pone.0152886 |
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2016 Journal Article A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patientsChai, Ryan C., Lim, Yenkai, Frazer, Ian H., Wan, Yunxia, Perry, Christopher, Jones, Lee, Lambie, Duncan and Punyadeera, Chamindie (2016). A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patients. Bmc Cancer, 16 (1) 178, 178. doi: 10.1186/s12885-016-2217-1 |
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2016 Conference Publication Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skinJung, Ji-Won, Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne Exhibition and Convention Centre, Melbourne, Australia, 7-9 November 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing. |
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2016 Conference Publication CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skinCruz, Gonzalez J. L., Overgaard, N. H., Bridge, J. A., Jung, J. -W, He, J., Nel, H. J., Watson, K., Frazer, I. H., La Gruta, N. L., Steptoe, R. J. and Wells, J. W. (2016). CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Novel regulators of CD8 T-cell functions in the skinBridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L. G., Veitch, Margaret, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2016). Novel regulators of CD8 T-cell functions in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular and Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia , November 7–9, 2016. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/wrr.12489 |
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2016 Conference Publication The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinomaJung, Ji-Won, Taylor, Paul J., Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-B055 |
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2016 Conference Publication Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced epithelium hyperplasiaKuo, P., Tuong, K., Mattarollo, S. and Frazer, I. (2016). Pre-malignant immune suppressive environment is dependent on HPV16E7-Rb interaction induced epithelium hyperplasia. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Novel regulators of CD8(+) T-cell functions in the skinBridge, J. A., Overgaard, N. H., Cruz, J. L. G., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Novel regulators of CD8(+) T-cell functions in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-16 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Immunotherapy for persisting viral infection and associated cancerFrazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Uncovering novel regulators of CD8(+) T-cell functions in the skinBridge, J. A., Overgaard, N. H., Cruz, J. L., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Uncovering novel regulators of CD8(+) T-cell functions in the skin. Asia-Pacific Combined Dermatology Research Conference, Noosa, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/ajd.12584 |
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2016 Conference Publication Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancersMattarollo, Stephen, Leggatt, Graham, Wells, James, Lambert, Paul and Frazer, Ian H. (2016). Modeling checkpoint blockade inhibitor resistant immunoregulation induced by squamous epithelial cancers. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-A064 |
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2016 Conference Publication Trafficking of E7 specific CD8 T cells from the host to hyperproliferative graftJazayeri, S. D. and Frazer, I. H. (2016). Trafficking of E7 specific CD8 T cells from the host to hyperproliferative graft. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancersBridge, Jennifer A., Overgaard, Nana H., Steptoe, Raymond J., Frazer, Ian H. and Wells, James W. (2016). Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancers. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, La, United States, Apr 16-20, 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3999 |
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2016 Conference Publication Exhausted T cell signature enriched in HPV16 E7 mouse model and cervical intraepithelial neoplasia grade IIITuong, Z. K. , Kuo, P. , Sinha, R. , Tolley, L. and Frazer, I. H. (2016). Exhausted T cell signature enriched in HPV16 E7 mouse model and cervical intraepithelial neoplasia grade III. ICI 2016 International Congress of Immunology, Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley-VCH. doi: 10.1002/eji.201670200 |
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2015 Journal Article Interleukin-17A promotes arginase-1 production and 2,4-dinitrochlorobenzene-induced acute hyperinflammation in human papillomavirus E7 oncoprotein-expressing skinTran, Le Son, Mittal, Deepak, Mattarollo, Stephen R. and Frazer, Ian H. (2015). Interleukin-17A promotes arginase-1 production and 2,4-dinitrochlorobenzene-induced acute hyperinflammation in human papillomavirus E7 oncoprotein-expressing skin. Journal of Innate Immunity, 7 (4), 392-404. doi: 10.1159/000374115 |
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2015 Journal Article Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermisAbd Warif, Nor Malia, Stoitzner, Patrizia, Leggatt, Graham R., Mattarollo, Stephen R., Frazer, Ian H. and Hibma, Merilyn H. (2015). Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis. PLoS One, 10 (5) e0127155, e0127155-e0127155. doi: 10.1371/journal.pone.0127155 |
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2015 Journal Article Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450 |
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2015 Journal Article HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesionsBergot, Anne-Sophie, Monnet, Nastasia, Tran, Son Le, Mittal, Deepak, Al-Kouba, Jane, Steptoe, Raymond J., Grimbaldeston, Michele A., Frazer, Ian H. and Wells, James W. (2015). HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunology and Cell Biology, 93 (6), 540-547. doi: 10.1038/icb.2014.123 |
