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2011

Journal Article

Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization

Chen, Xianfeng, Fernando, Germain J. P., Crichton, Michael L., Flaim, Christopher, Yukiko, Sally R., Fairmaid, Emily J., Corbett, Holly J., Primiero, Clare A., Ansaldo, Alexander B., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2011). Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization. Journal of Controlled Release, 152 (3), 349-355. doi: 10.1016/j.jconrel.2011.02.026

Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization

2011

Journal Article

Increasing mechanical stimulus induces migration of Langerhans cells and impairs the immune response to intracutaneously delivered antigen

Ruutu, Merja P., Chen, Xianfeng, Joshi, Ojas, Kendall, Mark A. and Frazer, Ian H. (2011). Increasing mechanical stimulus induces migration of Langerhans cells and impairs the immune response to intracutaneously delivered antigen. Experimental Dermatology, 20 (6), 534-536. doi: 10.1111/j.1600-0625.2010.01234.x

Increasing mechanical stimulus induces migration of Langerhans cells and impairs the immune response to intracutaneously delivered antigen

2011

Journal Article

Human papillomavirus 16 E7 protein inhibits interferon-gamma-mediated enhancement of keratinocyte antigen processing and T-cell lysis

Zhou, Fang, Leggatt, Graham R. and Frazer, Ian H. (2011). Human papillomavirus 16 E7 protein inhibits interferon-gamma-mediated enhancement of keratinocyte antigen processing and T-cell lysis. The Federation of European Biochemical Societies (FEBS) Journal, 278 (6), 955-963. doi: 10.1111/j.1742-4658.2011.08011.x

Human papillomavirus 16 E7 protein inhibits interferon-gamma-mediated enhancement of keratinocyte antigen processing and T-cell lysis

2011

Journal Article

Prevention and treatment of papillomavirus-related cancers through immunization

Frazer, Ian H., Leggatt, Graham R. and Mattarollo, Stephen R. (2011). Prevention and treatment of papillomavirus-related cancers through immunization. Annual Review of Immunology, 29, 111-138. doi: 10.1146/annurev-immunol-031210-101308

Prevention and treatment of papillomavirus-related cancers through immunization

2011

Journal Article

Regulation of immune responses to HPVinfection and during HPV-directed immunotherapy

Bhat, Purnima, Mattarollo, Stephen R., Gosmann, Christina, Frazer, Ian H. and Leggatt, Graham R. (2011). Regulation of immune responses to HPVinfection and during HPV-directed immunotherapy. Immunological Reviews, 239 (1), 85-98. doi: 10.1111/j.1600-065X.2010.00966.x

Regulation of immune responses to HPVinfection and during HPV-directed immunotherapy

2010

Journal Article

Skin vaccination against cervical cancer associated human papillomavirus with a novel micro-projection array in a mouse model

Corbett, Holly J., Fernando, Germain J. P., Chen, Xianfeng, Frazer, Ian H. and Kendall, Mark A. F. (2010). Skin vaccination against cervical cancer associated human papillomavirus with a novel micro-projection array in a mouse model. PLoS One, 5 (10) e13460, e13460.1-e13460.9. doi: 10.1371/journal.pone.0013460

Skin vaccination against cervical cancer associated human papillomavirus with a novel micro-projection array in a mouse model

2010

Journal Article

Development of therapeutic HPV vaccines

Trimble, C. L. and Frazer, Ian H. (2010). Development of therapeutic HPV vaccines. Lancet Oncology, 10 (10), 975-980. doi: 10.1016/S1470-2045(09)70227-X

Development of therapeutic HPV vaccines

2010

Journal Article

Evaluation of a cervical cancer screening program based on HPV testing and LLETZ excision in a low resource setting

McAdam, Margaret, Sakita, Jerol, Tarivonda, Len, Pang, James and Frazer, Ian H. (2010). Evaluation of a cervical cancer screening program based on HPV testing and LLETZ excision in a low resource setting. PLoS One, 5 (10) e13266, e13266.1-e13266.6. doi: 10.1371/journal.pone.0013266

Evaluation of a cervical cancer screening program based on HPV testing and LLETZ excision in a low resource setting

2010

Journal Article

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

Hadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010). IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 (8), 723-729. doi: 10.1111/j.1600-0625.2010.01092.x

IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes

2010

Journal Article

Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice

Prow, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331

Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice

2010

Journal Article

Antigen-specific CD8 T cells can eliminate antigen-bearing keratinocytes with clonogenic potential via an IFN-γ-dependent mechanism

De Kluyver, Rachel L., Moritz, Linnea, Harris, Craig A., Azukizawa, Hiroaki and Frazer, Ian H. (2010). Antigen-specific CD8 T cells can eliminate antigen-bearing keratinocytes with clonogenic potential via an IFN-γ-dependent mechanism. Journal of Investigative Dermatology, 130 (7), 1841-1848. doi: 10.1038/jid.2010.49

Antigen-specific CD8 T cells can eliminate antigen-bearing keratinocytes with clonogenic potential via an IFN-γ-dependent mechanism

2010

Journal Article

Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes

Broom, Jennifer K., Lew, Andrew M., Azukizawa, Hiroaki, Kenna, Tony J., Leggatt, Graham R. and Frazer, Ian H. (2010). Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes. Journal of Investigative Dermatology, 130 (6), 1581-1589. doi: 10.1038/jid.2010.17

Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes

2010

Journal Article

Measuring serum antibody to human papillomavirus following infection or vaccination

Frazer, Ian H. (2010). Measuring serum antibody to human papillomavirus following infection or vaccination. Gynecologic Oncology, 118 (1 Supplement 1), S8-S11. doi: 10.1016/j.ygyno.2010.04.003

Measuring serum antibody to human papillomavirus following infection or vaccination

2010

Journal Article

Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen

Mattarollo, Stephen R., Yong, Michelle, Tan, Lieven, Frazer, Ian H. and Leggatt, Graham R. (2010). Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen. Journal of Immunology, 184 (10), 5663-5669. doi: 10.4049/jimmunol.0903730

Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen

2010

Journal Article

The two faces of human papillomavirus

Frazer, Ian H. (2010). The two faces of human papillomavirus. Gynecologic Oncology, 117 (2), S4-S4. doi: 10.1016/j.ygyno.2010.01.023

The two faces of human papillomavirus

2010

Journal Article

Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes

Ding, Jianmin, Doorbar, John, Li, Bo, Zhou, Fang, Gu, Wenyi, Zhao, Liang, Saunders, Nicholas A., Frazer, Ian H. and Zhao, Kong-Nan (2010). Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes. Virology, 399 (1), 46-58. doi: 10.1016/j.virol.2009.12.021

Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes

2010

Journal Article

Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-gamma Production

Mattarollo, Stephen R., Rahimpour, Azad, Choyce, Allison, Godfrey, Dale I., Leggatt, Graham R. and Frazer, Ian H. (2010). Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-gamma Production. Journal of Immunology, 184 (3), 1242-1250. doi: 10.4049/jimmunol.0902191

Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-gamma Production

2010

Journal Article

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control

Ferreira, Mar, Mangino, M, Brumme, CJ, Zhao, ZZ, Medland, SE, Wright, MJ, Nyholt, DR, Gordon, S, Campbell, M, McEvoy, BP, Henders, A, Evans, DM, Lanchbury, JS, Pereyra, F, Walker, BD, Haas, DW, Soranzo, N, Spector, TD, de Bakker, PIW, Frazer, IH, Montgomery, GW, Martin, NG and Int HIV Controllers Study (2010). Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. American Journal of Human Genetics, 86 (1), 88-92. doi: 10.1016/j.ajhg.2009.12.008

Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control

2010

Journal Article

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model

Fernando, Germain J. P., Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Fairmaid, Emily J., Roberts, Michael S., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2010). Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One, 5 (4) e10266, e10266.1-e10266.11. doi: 10.1371/journal.pone.0010266

Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model

2010

Book Chapter

Vaccines against human papillomaviruses

Jansen, Kathrin U. and Frazer, Ian H. (2010). Vaccines against human papillomaviruses. New generation vaccines. (pp. 954-961) edited by Myron M. Levine. New York, U.S.A.: Informa Healthcare.

Vaccines against human papillomaviruses