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2022

Conference Publication

Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues

Kulasinghe, Arutha, Tan, Chin Wee, Liu, Ning, Monkman, James, Killingbeck, Emily, Kim, Youngmi, Pan, Liuliu, Blick, Tony, Bhuva, Dharmesh, Feher, Kristen, Leon, Michael, Gregory, Mark, Short, Kirsty, Guimaraes, Fernando, Rhodes, Michael, Belz, Gabrielle and Davis, Melissa (2022). Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues. SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0923

Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues

2022

Conference Publication

High dimensional immuno-phenotyping of immunotherapy response in head and neck cancer

O'Byrne, K. J., Ma, N., Sadeghirad, H., Jhaveri, N., Monkman, J., Pratapa, A., Cheikh, B. Ben, Ladwa, R., Hughes, B. G. M., Braubach, O. and Kulasinghe, A. (2022). High dimensional immuno-phenotyping of immunotherapy response in head and neck cancer. Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), Electr Network, Sep 09-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1016/j.annonc.2022.07.778

High dimensional immuno-phenotyping of immunotherapy response in head and neck cancer

2022

Journal Article

Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications

Radfar, Payar, Aboulkheyr Es, Hamidreza, Salomon, Rob, Kulasinghe, Arutha, Ramalingam, Naveen, Sarafraz-Yazdi, Ehsan, Thiery, Jean Paul and Warkiani, Majid Ebrahimi (2022). Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications. Trends in Biotechnology, 40 (9), 1041-1060. doi: 10.1016/j.tibtech.2022.02.004

Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications

2022

Conference Publication

High dimensional spatial profiling of the NSCLC tumour microenvironment

Kulasinghe, A., Ma, N., Monkman, J., Pratapa, A., Braubach, O. and O'Byrne, K. (2022). High dimensional spatial profiling of the NSCLC tumour microenvironment. 2022 World Conference on Lung Cancer, Vienna, Austria, 6-9 August 2022. New York, United States: Elsevier. doi: 10.1016/j.jtho.2022.07.1111

High dimensional spatial profiling of the NSCLC tumour microenvironment

2022

Journal Article

Immunotherapeutic targets in non‐small cell lung cancer

Sadeghi Rad, Habib, Bahrami, Tayyeb, Layeghi, Sepideh Mehrpour, Yousefi, Hassan, Rezaei, Meysam, Hosseini‐Fard, Seyed Reza, Radfar, Payar, Warkiani, Majid Ebrahimi, O’Byrne, Ken and Kulasinghe, Arutha (2022). Immunotherapeutic targets in non‐small cell lung cancer. Immunology, 168 (2), 1-17. doi: 10.1111/imm.13562

Immunotherapeutic targets in non‐small cell lung cancer

2022

Journal Article

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

Tran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

2022

Conference Publication

Profiling spatial signatures in the microenvironment of non-small cell lung carcinomas in immunotherapy responsive and resistant disease cohorts

Kulasinghe, Arutha, Ma, Ning, Monkman, James, Mammadova, Najiba, Braubach, Oliver and O'Byrne, Ken (2022). Profiling spatial signatures in the microenvironment of non-small cell lung carcinomas in immunotherapy responsive and resistant disease cohorts. AACR Annual Meeting 2022, New Orleans, LA United States, 8-13 April 2022. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2022-1714

Profiling spatial signatures in the microenvironment of non-small cell lung carcinomas in immunotherapy responsive and resistant disease cohorts

2022

Conference Publication

Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types

Grice, Laura, Ni, Guiyan, Jin, Xinnan, Tran, Minh, Killingbeck, Emily, Gregory, Mark, Mulay, Onkar, Teoh, Siok-Min, Kulasinghe, Arutha, Leon, Michael, Murphy, Sarah, Warren, Sarah, Kim, Youngmi and Nguyen, Quan (2022). Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types. American Association for Cancer Research Annual Meeting, Philadelphia, PA, United States, 8-13 April 2022. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2022-3817

Abstract 3817: A single-cell, spatial multiomics atlas and cellular interactome of all major skin cancer types

2022

Conference Publication

Multi-omic dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC)

Kulasinghe, Arutha, Monkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott, Adams, Mark and O'Byrne, Ken (2022). Multi-omic dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC). AACR Annual Meeting 2022, New Orleans, LA United States, 8-13 April 2022. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2022-2036

Multi-omic dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC)

2022

Conference Publication

Multi-omic and spatial dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC)

O'Byrne, Kenneth John, Monkman, James, Kim, Honesty, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Adams, Mark N. and Kulasinghe, Arutha (2022). Multi-omic and spatial dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC). Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 03-07, 2022. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Multi-omic and spatial dissection of immunotherapy response groups in non-small cell lung cancer (NSCLC)

2022

Conference Publication

Multi-omic and spatial dissection of immunotherapy response groups in non–small cell lung cancer (NSCLC)

O'Byrne, Kenneth John, Monkman, James, Kim, Honesty, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Adams, Mark N. and Kulasinghe, Arutha (2022). Multi-omic and spatial dissection of immunotherapy response groups in non–small cell lung cancer (NSCLC). 2022 ASCO Annual Meeting, Chicago, IL, United States, 3-7 June 2022. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/jco.2022.40.16_suppl.8544

Multi-omic and spatial dissection of immunotherapy response groups in non–small cell lung cancer (NSCLC)

2022

Journal Article

Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas

Sadeghirad, Habib, Monkman, James, Mehdi, Ahmed M., Ladwa, Rahul, O’Byrne, Ken, Hughes, Brett G. M. and Kulasinghe, Arutha (2022). Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas. Frontiers in Immunology, 13 895513, 1-11. doi: 10.3389/fimmu.2022.895513

Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas

2022

Conference Publication

Mapping the spatial biology of COVID-19 immunopathology in placenta tissues

Ma, Ning, Braubach, Oliver, Rebutini, Patricia Zadorosnei, Machado-Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, de Noronha, Lucia, Souza-Fonseca-Guimaraes, Fernando and Kulasinghe, Arutha (2022). Mapping the spatial biology of COVID-19 immunopathology in placenta tissues. Immunology 2022 Meeting, Portland, OR United States, 6-10 May 2022. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.208.supp.125.20

Mapping the spatial biology of COVID-19 immunopathology in placenta tissues

2022

Journal Article

Immune checkpoint inhibitors in cancer therapy

Shiravand, Yavar, Khodadadi, Faezeh, Kashani, Seyyed Mohammad Amin, Hosseini-Fard, Seyed Reza, Hosseini, Shadi, Sadeghirad, Habib, Ladwa, Rahul, O’Byrne, Ken and Kulasinghe, Arutha (2022). Immune checkpoint inhibitors in cancer therapy. Current Oncology, 29 (5), 3044-3060. doi: 10.3390/curroncol29050247

Immune checkpoint inhibitors in cancer therapy

2022

Journal Article

Clinical applications of circulating tumour cells and circulating tumour dna in non-small cell lung cancer—an update

Kapeleris, Joanna, Ebrahimi Warkiani, Majid, Kulasinghe, Arutha, Vela, Ian, Kenny, Liz, Ladwa, Rahul, O’Byrne, Kenneth and Punyadeera, Chamindie (2022). Clinical applications of circulating tumour cells and circulating tumour dna in non-small cell lung cancer—an update. Frontiers in Oncology, 12 859152, 1-18. doi: 10.3389/fonc.2022.859152

Clinical applications of circulating tumour cells and circulating tumour dna in non-small cell lung cancer—an update

2022

Journal Article

The role of circulating biomarkers in lung cancer

Herath, Sayuri, Sadeghi Rad, Habib, Radfar, Payar, Ladwa, Rahul, Warkiani, Majid, O’Byrne, Ken and Kulasinghe, Arutha (2022). The role of circulating biomarkers in lung cancer. Frontiers in Oncology, 11 801269, 1-13. doi: 10.3389/fonc.2021.801269

The role of circulating biomarkers in lung cancer

2022

Journal Article

Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC)

Kulasinghe, Arutha, Monkman, James, Shah, Esha T., Matigian, Nicholas, Adams, Mark N. and O’Byrne, Ken (2022). Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC). Frontiers in Oncology, 11 798296, 798296. doi: 10.3389/fonc.2021.798296

Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC)

2022

Journal Article

Corrigendum: The effects of COVID-19 on the placenta during pregnancy

Rad, Habib Sadeghi, Röhl, Joan, Stylianou, Nataly, Allenby, Mark C., Bazaz, Sajad Razavi, Warkiani, Majid E., Guimaraes, Fernando S F, Clifton, Vicki L. and Kulasinghe, Arutha (2022). Corrigendum: The effects of COVID-19 on the placenta during pregnancy. Frontiers in immunology, 13 998406, 998406. doi: 10.3389/fimmu.2022.998406

Corrigendum: The effects of COVID-19 on the placenta during pregnancy

2022

Journal Article

Understanding the tumor microenvironment in head and neck squamous cell carcinoma

Rad, Habib Sadeghi, Shiravand, Yavar, Radfar, Payar, Ladwa, Rahul, Perry, Chris, Han, Xiaoyuan, Warkiani, Majid Ebrahimi, Adams, Mark N., Hughes, Brett G.M., O'Byrne, Ken and Kulasinghe, Arutha (2022). Understanding the tumor microenvironment in head and neck squamous cell carcinoma. Clinical & Translational Immunology, 11 (6) e1397, e1397. doi: 10.1002/cti2.1397

Understanding the tumor microenvironment in head and neck squamous cell carcinoma

2022

Journal Article

Modelling the tumor immune microenvironment for precision immunotherapy

Mackenzie, Nathan J, Nicholls, Clarissa, Templeton, Abby R, Perera, Mahasha PJ, Jeffery, Penny L, Zimmermann, Kate, Kulasinghe, Arutha, Kenna, Tony J, Vela, Ian, Williams, Elizabeth D and Thomas, Patrick B (2022). Modelling the tumor immune microenvironment for precision immunotherapy. Clinical and Translational Immunology, 11 (6) e1400, 1-22. doi: 10.1002/cti2.1400

Modelling the tumor immune microenvironment for precision immunotherapy