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2018 Journal Article Extracellular matrix protein production in human adipose-derived mesenchymal stem cells on three-dimensional polycaprolactone (PCL) scaffolds responds to GDF5 or FGF2Su, Yan, Denbeigh, Janet M., Camilleri, Emily T., Riester, Scott M., Parry, Joshua A., Wagner, Eric R., Yaszemski, Michael J., Dietz, Allan B., Cool, Simon M., van Wijnen, Andre J. and Kakar, Sanjeev (2018). Extracellular matrix protein production in human adipose-derived mesenchymal stem cells on three-dimensional polycaprolactone (PCL) scaffolds responds to GDF5 or FGF2. Gene Reports, 10, 149-156. doi: 10.1016/j.genrep.2017.12.004 |
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2018 Journal Article Osteogenic stimulation of human adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the polycomb group protein EZH2Samsonraj, Rebekah M., Dudakovic, Amel, Manzar, Bushra, Sen, Buer, Dietz, Allan B., Cool, Simon M., Rubin, Janet and van Wijnen, Andre J. (2018). Osteogenic stimulation of human adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the polycomb group protein EZH2. Stem Cells Translational Medicine, 7 (2), 197-209. doi: 10.1002/sctm.17-0086 |
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2017 Journal Article The components of bone and what they can teach us about regenerationLe, Bach Quang, Nurcombe, Victor, Cool, Simon McKenzie, van Blitterswijk, Clemens A., de Boer, Jan and LaPointe, Vanessa Lydia Simone (2017). The components of bone and what they can teach us about regeneration. Materials, 11 (1) 14, 14. doi: 10.3390/ma11010014 |
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2017 Journal Article Fabrication of polycaprolactone-silanated β-tricalcium phosphate-heparan sulfate scaffolds for spinal fusion applicationsBhakta, Gajadhar, Ekaputra, Andrew K., Rai, Bina, Abbah, Sunny A., Tan, Tuan Chun, Le, Bach Quang, Chatterjea, Anindita, Hu, Tao, Lin, Tingxuan, Arafat, M. Tarik, van Wijnen, Andre J., Goh, James, Nurcombe, Victor, Bhakoo, Kishore, Birch, William, Xu, Li, Gibson, Ian, Wong, Hee-Kit and Cool, Simon M. (2017). Fabrication of polycaprolactone-silanated β-tricalcium phosphate-heparan sulfate scaffolds for spinal fusion applications. Spine Journal, 18 (5), 818-830. doi: 10.1016/j.spinee.2017.12.002 |
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2017 Journal Article Concise review: Multifaceted characterization of human mesenchymal stem cells for use in regenerative medicineSamsonraj, Rebekah M., Raghunath, Michael, Nurcombe, Victor, Hui, James H., van Wijnen, Andre J. and Cool, Simon M. (2017). Concise review: Multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine. Stem Cells Translational Medicine, 6 (12), 2173-2185. doi: 10.1002/sctm.17-0129 |
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2017 Journal Article A versatile protocol for studying calvarial bone defect healing in a mouse modelSamsonraj, Rebekah M., Dudakovic, Amel, Zan, Pengfei, Pichurin, Oksana, Cool, Simon M. and Van Wijnen, Andre J. (2017). A versatile protocol for studying calvarial bone defect healing in a mouse model. Tissue Engineering - Part C: Methods, 23 (11), 686-693. doi: 10.1089/ten.tec.2017.0205 |
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2017 Journal Article Endogenous regeneration: Engineering growth factors for strokeChan, Su Jing, Love, Christopher, Spector, Myron, Cool, Simon M., Nurcombe, Victor and Lo, Eng H. (2017). Endogenous regeneration: Engineering growth factors for stroke. Neurochemistry International, 107, 57-65. doi: 10.1016/j.neuint.2017.03.024 |
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2017 Journal Article Long-term culture of self-renewing pancreatic progenitors derived from human pluripotent stem cellsTrott, Jamie, Tan, Ee Kim, Ong, Sheena, Titmarsh, Drew M., Denil, Simon L. I. J., Giam, Maybelline, Wong, Cheng Kit, Wang, Jiaxu, Shboul, Mohammad, Eio, Michelle, Cooper-White, Justin, Cool, Simon M., Rancati, Giulia, Stanton, Lawrence W., Reversade, Bruno and Dunn, N. Ray (2017). Long-term culture of self-renewing pancreatic progenitors derived from human pluripotent stem cells. Stem Cell Reports, 8 (6), 1675-1688. doi: 10.1016/j.stemcr.2017.05.019 |
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2017 Journal Article Growth differentiation factor 5-mediated enhancement of chondrocyte phenotype is inhibited by heparin: implications for the use of heparin in the clinic and in tissue engineering applicationsAyerst, Bethanie I., Smith, Raymond A.A., Nurcombe, Victor, Day, Anthony J., Merry, Catherine L.R. and Cool, Simon M. (2017). Growth differentiation factor 5-mediated enhancement of chondrocyte phenotype is inhibited by heparin: implications for the use of heparin in the clinic and in tissue engineering applications. Tissue Engineering - Part A, 23 (7-8), 275-292. doi: 10.1089/ten.tea.2016.0364 |
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2017 Journal Article Microfluidic screening reveals heparan sulfate enhances human mesenchymal stem cell growth by modulating fibroblast growth factor-2 transportTitmarsh, Drew M., Tan, Clarissa L. L., Glass, Nick R., Nurcombe, Victor, Cooper-White, Justin J. and Cool, Simon M. (2017). Microfluidic screening reveals heparan sulfate enhances human mesenchymal stem cell growth by modulating fibroblast growth factor-2 transport. Stem Cells Translational Medicine, 6 (4), 1178-1190. doi: 10.1002/sctm.16-0343 |
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2017 Journal Article Affinity selection of FGF2-binding heparan sulfates for ex vivo expansion of human mesenchymal stem cellsWijesinghe, Sampath Jeewantha, Ling, Ling, Murali, Sadasivam, Qing, Yeong Hui, Hinkley, Simon F.R., Carnachan, Susan M., Bell, Tracey J., Swaminathan, Kunchithapadam, Hui, James H., van Wijnen, Andre J., Nurcombe, Victor and Cool, Simon M. (2017). Affinity selection of FGF2-binding heparan sulfates for ex vivo expansion of human mesenchymal stem cells. Journal of Cellular Physiology, 232 (3), 566-575. doi: 10.1002/jcp.25454 |
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2016 Journal Article Determining the extent of heparan sulfate depolymerisation following heparin lyase treatmentCarnachan, Susan M., Bell, Tracey J., Sims, Ian M., Smith, Raymond A.A., Nurcombe, Victor, Cool, Simon M. and Hinkley, Simon F.R. (2016). Determining the extent of heparan sulfate depolymerisation following heparin lyase treatment. Carbohydrate Polymers, 152, 592-597. doi: 10.1016/j.carbpol.2016.07.024 |
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2016 Journal Article The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytesLewallen, Eric A., Bonin, Carolina A., Li, Xin, Smith, Jay, Karperien, Marcel, Larson, A. Noelle, Lewallen, David G., Cool, Simon M., Westendorf, Jennifer J., Krych, Aaron J., Leontovich, Alexey A., Im, Hee-Jeong and van Wijnen, Andre J. (2016). The synovial microenvironment of osteoarthritic joints alters RNA-seq expression profiles of human primary articular chondrocytes. Gene, 591 (2), 456-464. doi: 10.1016/j.gene.2016.06.063 |
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2016 Journal Article Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant productionCamilleri, Emily T., Gustafson, Michael P., Dudakovic, Amel, Riester, Scott M., Garces, Catalina Galeano, Paradise, Christopher R., Takai, Hideki, Karperien, Marcel, Cool, Simon, Sampen, Hee-Jeong Im, Larson, A. Noelle, Qu, Wenchun, Smith, Jay, Dietz, Allan B. and Van Wijnen, Andre J. (2016). Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production. Stem Cell Research and Therapy, 7 (1) 107, 1-16. doi: 10.1186/s13287-016-0370-8 |
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2016 Journal Article Heparin-based polyelectrolyte complex enhances the therapeutic efficacy of bone morphogenetic protein-2 for posterolateral fusion in a large animal modelWang, Ming, Lam, Raymond W.M., Abbah, Sunny A., Hu, Tao, Toh, Soo Y., Cool, Simon, Bhakoo, Kishore, Li, Jun, Goh, James C.H. and Wong, Hee-Kit (2016). Heparin-based polyelectrolyte complex enhances the therapeutic efficacy of bone morphogenetic protein-2 for posterolateral fusion in a large animal model. Spine, 41 (15), 1199-1207. doi: 10.1097/BRS.0000000000001543 |
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2016 Journal Article Effect of heparin on the biological properties and molecular signature of human mesenchymal stem cellsLing, Ling, Camilleri, Emily T., Helledie, Torben, Samsonraj, Rebekah M., Titmarsh, Drew M., Chua, Ren Jie, Dreesen, Oliver, Dombrowski, Christian, Rider, David A., Galindo, Mario, Lee, Ian, Hong, Wanjin, Hui, James H., Nurcombe, Victor, van Wijnen, Andre J. and Cool, Simon M. (2016). Effect of heparin on the biological properties and molecular signature of human mesenchymal stem cells. Gene, 576 (1), 292-303. doi: 10.1016/j.gene.2015.10.039 |
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2015 Journal Article Mode of heparin attachment to nanocrystalline hydroxyapatite affects its interaction with bone morphogenetic protein-2Goonasekera, Chandhi S., Jack, Kevin S., Bhakta, Gajadhar, Rai, Bina, Luong-Van, Emma, Nurcombe, Victor, Cool, Simon M., Cooper-White, Justin J. and Grondahl, Lisbeth (2015). Mode of heparin attachment to nanocrystalline hydroxyapatite affects its interaction with bone morphogenetic protein-2. Biointerphases, 10 (4) 04A308, 1-12. doi: 10.1116/1.4933109 |
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2015 Journal Article Repair of segmental ulna defects using a β-TCP implant in combination with a heparan sulfate glycosaminoglycan variantRai, B., Chatterjea, A., Lim, Z. X.H., Tan, T. C., Sawyer, A. A., Hosaka, Y. Z., Murali, S., Lee, J. J.L., Fenwick, S. A., Hui, J. H., Nurcombe, V. and Cool, S. M. (2015). Repair of segmental ulna defects using a β-TCP implant in combination with a heparan sulfate glycosaminoglycan variant. Acta Biomaterialia, 28, 193-204. doi: 10.1016/j.actbio.2015.09.008 |
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2015 Journal Article Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signalingLee, Jonathan, Wee, Sheena, Gunaratne, Jayantha, Chua, R. J. E., Smith, Raymond A. A., Ling, Ling, Fernig, David G., Swaminathan, Kunchithapadam, Nurcombe, Victor and Cool, Simon M. (2015). Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signaling. Glycobiology, 25 (12), 1491-1504. doi: 10.1093/glycob/cwv064 |
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2015 Journal Article Human mesenchymal stem cells retain multilineage differentiation capacity including neural marker expression after extended in vitro expansionOkolicsanyi, Rachel K., Camilleri, Emily T., Oikari, Lotta E., Yu, Chieh, Cool, Simon M., Van Wijnen, Andre J., Griffiths, Lyn R. and Haupt, Larisa M. (2015). Human mesenchymal stem cells retain multilineage differentiation capacity including neural marker expression after extended in vitro expansion. PLoS One, 10 (9) e0137255, 1-29. doi: 10.1371/journal.pone.0137255 |
