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2020 Journal Article Heparan sulfate proteoglycans: key mediators of stem cell functionRavikumar, Maanasa, Smith, Raymond Alexander Alfred, Nurcombe, Victor and Cool, Simon M. (2020). Heparan sulfate proteoglycans: key mediators of stem cell function. Frontiers in Cell and Developmental Biology, 8 581213, 581213. doi: 10.3389/fcell.2020.581213 |
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2020 Journal Article A genomic biomarker that identifies human bone marrow-derived mesenchymal stem cells with high scalabilitySathiyanathan, Padmapriya, Samsonraj, Rebekah M., Tan, Clarissa L. L., Ling, Ling, Lezhava, Alexander, Nurconnbe, Victor, Stanton, Lawrence W. and Cool, Simon M. (2020). A genomic biomarker that identifies human bone marrow-derived mesenchymal stem cells with high scalability. Stem Cells, 38 (9), 1124-1136. doi: 10.1002/stem.3203 |
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2020 Journal Article Vascular endothelial growth factor 165-binding heparan sulfate promotes functional recovery from cerebral ischemiaChan, Su Jing, Esposito, Elga, Hayakawa, Kazuhide, Mandaville, Emiri, Smith, Raymond A. A., Guo, Shuzhen, Niu, Wanting, Wong, Peter Tsun-Hong, Cool, Simon M., Lo, Eng H. and Nurcombe, Victor (2020). Vascular endothelial growth factor 165-binding heparan sulfate promotes functional recovery from cerebral ischemia. Stroke, 51 (9), 2844-2853. doi: 10.1161/STROKEAHA.119.025304 |
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2020 Journal Article In replyCool, Simon M., Sathiyanathan, Padmapriya, Samsonraj, Rebekah M., Tan, Clarissa L. L., Ling, Ling, Lezhava, Alexander, Nurcombe, Victor and Stanton, Lawrence W. (2020). In reply. Stem Cells, 38 (11), E7-E8. doi: 10.1002/stem.3264 |
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2020 Journal Article Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2Dudakovic, Amel, Samsonraj, Rebekah M., Paradise, Christopher R., Galeano-Garces, Catalina, Mol, Merel O., Galeano-Garces, Daniela, Zan, Pengfei, Galvan, M Lizeth, Hevesi, Mario, Pichurin, Oksana, Thaler, Roman, Begun, Dana L., Kloen, Peter, Karperien, Marcel, Larson, A. Noelle, Westendorf, Jennifer J., Cool, Simon M. and van Wijnen, Andre J. (2020). Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. The Journal of Biological Chemistry, 295 (23), 7877-7893. doi: 10.1074/jbc.RA119.011685 |
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2020 Conference Publication A synthetic heparan sulphate mimetic for enhancing BMP-2-mediated osteogenesis and bone regenerationSmith, R.A., Lu, X., Tan, T., Luo, X., Le, B.Q., Zubkova, O.V., Cool, S. and Nurcombe, V. (2020). A synthetic heparan sulphate mimetic for enhancing BMP-2-mediated osteogenesis and bone regeneration. ISCT 2020, Paris, France, 26-29 May 2020. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jcyt.2020.03.017 |
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2020 Journal Article Ascorbate and iron are required for the specification and long-term self-renewal of human skeletal mesenchymal stromal cellsLiu, Tong Ming, Yildirim, Ege Deniz, Li, Pin, Fang, Hai Tong, Denslin, Vinitha, Kumar, Vibhor, Loh, Yuin Han, Lee, Eng Hin, Cool, Simon M., Teh, Bin Tean, Hui, James H., Lim, Bing and Shyh-Chang, Ng (2020). Ascorbate and iron are required for the specification and long-term self-renewal of human skeletal mesenchymal stromal cells. Stem Cell Reports, 14 (2), 210-225. doi: 10.1016/j.stemcr.2020.01.002 |
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2020 Journal Article Enhancing the efficacy of stem cell therapy with glycosaminoglycansLing, Ling, Ren, Xiafei, Cao, Xue, Hassan, Afizah Binte Mohd, Mah, Sophia, Sathiyanathan, Padmapriya, Smith, Raymond A. A., Tan, Clarissa L. L., Eio, Michelle, Samsonraj, Rebekah M., Van Wijnen, Andre J., Raghunath, Michael, Nurcombe, Victor, Hui, James H. and Cool, Simon M. (2020). Enhancing the efficacy of stem cell therapy with glycosaminoglycans. Stem Cell Reports, 14 (1), 105-121. doi: 10.1016/j.stemcr.2019.12.003 |
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2019 Journal Article Bringing heparan sulfate glycomics together with proteomics for the design of novel therapeutics: A historical perspectiveNurcombe, Victor, Ling, Ling, Hondermarck, Hubert, Cool, Simon M. and Smith, Raymond A. A. (2019). Bringing heparan sulfate glycomics together with proteomics for the design of novel therapeutics: A historical perspective. Proteomics, 19 (21-22) 1800466, 1800466. doi: 10.1002/pmic.201800466 |
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2019 Journal Article Vascular cells and tissue constructs derived from human pluripotent stem cells for toxicological screeningTitmarsh, Drew M., Nurcombe, Victor, Cheung, Christine and Cool, Simon M. (2019). Vascular cells and tissue constructs derived from human pluripotent stem cells for toxicological screening. Stem Cells and Development, 28 (20), 1347-1364. doi: 10.1089/scd.2018.0246 |
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2019 Conference Publication Biomimicry of glycosaminoglycans in the bone marrow microenvironment favour the expansion of highly potent human mesenchymal stem cellsLing, L., Ren, X., Hassan, A. Binte Mohd, Mah, S., Smith, R. A., Tan, C., van Wijnen, A., Raghunath, M., Nurcombe, V., Hui, J. and Cool, S. (2019). Biomimicry of glycosaminoglycans in the bone marrow microenvironment favour the expansion of highly potent human mesenchymal stem cells. ISCT 2019, Melbourne, VIC Australia, 29 May - 1 June 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jcyt.2019.03.463 |
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2019 Journal Article A heparan sulfate device for the regeneration of osteochondral defectsLee, Jonathan H., Luo, Xiaoman, Ren, Xiafei, Tan, Tuan Chun, Smith, Raymond A.A., Swaminathan, Kunchithapadam, Sekar, Sakthivel, Bhakoo, Kishore, Nurcombe, Victor, Hui, James H. and Cool, Simon M. (2019). A heparan sulfate device for the regeneration of osteochondral defects. Tissue Engineering - Part A, 25 (5-6), 352-363. doi: 10.1089/ten.tea.2018.0171 |
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2019 Journal Article Autologous bone marrow clot as an alternative to autograft for bone defect healingLim, Z. X.H., Rai, B., Tan, T. C., Ramruttun, A. K., Hui, J. H., Nurcombe, V., Teoh, S. H. and Cool, S. M. (2019). Autologous bone marrow clot as an alternative to autograft for bone defect healing. Bone and Joint Research, 8 (3), 107-117. doi: 10.1302/2046-3758.83.BJR-2018-0096.R1 |
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2019 Journal Article A polycaprolactone-beta-tricalcium phosphateeheparan sulphate device for cranioplastyLe, Bach Quang, Rai, Bina, Lim, Zophia Xue Hui, Tan, Tuan Chun, Lin, Tingxuan, Lee, Jaslyn Jie Lin, Murali, Sadasivam, Teoh, Swee Hin, Nurcombe, Victor and Cool, Simon McKenzie (2019). A polycaprolactone-beta-tricalcium phosphateeheparan sulphate device for cranioplasty. Journal of Cranio-Maxillofacial Surgery, 47 (2), 341-348. doi: 10.1016/j.jcms.2018.11.013 |
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2018 Journal Article Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphatePoon, Selina, Lu, Xiaohua, Smith, Raymond A. A., Ho, Pei, Bhakoo, Kishore, Nurcombe, Victor and Cool, Simon M. (2018). Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphate. Angiogenesis, 21 (4), 777-791. doi: 10.1007/s10456-018-9622-9 |
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2018 Journal Article Minimum structural requirements for BMP-2-binding of heparin oligosaccharidesSmith, Raymond A.A., Murali, Sadasivam, Rai, Bina, Lu, Xiaohua, Lim, Zophia Xue Hui, Lee, Jaslyn J.L., Nurcombe, Victor and Cool, Simon M. (2018). Minimum structural requirements for BMP-2-binding of heparin oligosaccharides. Biomaterials, 184, 41-55. doi: 10.1016/j.biomaterials.2018.08.056 |
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2018 Journal Article Validation of osteogenic properties of cytochalasin D by high-resolution RNA-sequencing in mesenchymal stem cells derived from bone marrow and adipose tissuesSamsonraj, Rebekah M., Paradise, Christopher R., Dudakovic, Amel, Sen, Buer, Nair, Asha A., Dietz, Allan B., Deyle, David R., Cool, Simon M., Rubin, Janet and Van Wijnen, Andre J. (2018). Validation of osteogenic properties of cytochalasin D by high-resolution RNA-sequencing in mesenchymal stem cells derived from bone marrow and adipose tissues. Stem Cells and Development, 27 (16), 1136-1145. doi: 10.1089/scd.2018.0037 |
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2018 Journal Article Immobilization of vitronectin-binding heparan sulfates onto surfaces to support human pluripotent stem cellsYap, Lynn, Murali, Sadasivam, Bhakta, Gajadhar, Titmarsh, Drew M., Chen, Allen Kuan-Liang, Chiin Sim, Lyn, Bardor, Muriel, Lim, Yu Ming, Goh, James C.H., Oh, Steve K.W., Choo, Andre B.H., van Wijnen, Andre J., Robinson, David E., Whittle, Jason D., Birch, William R., Short, Robert D., Nurcombe, Victor and Cool, Simon M. (2018). Immobilization of vitronectin-binding heparan sulfates onto surfaces to support human pluripotent stem cells. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 106 (5), 1887-1896. doi: 10.1002/jbm.b.33999 |
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2018 Journal Article Fibrin glue mediated delivery of bone anabolic reagents to enhance healing of tendon to boneSoreide, Endre, Denbeigh, Janet M., Lewallen, Eric A., Samsonraj, Rebekah M., Berglund, Lawrence J., Dudakovic, Amel, Cool, Simon M., Nordsletten, Lars, Kakar, Sanjeev and van Wijnen, Andre J. (2018). Fibrin glue mediated delivery of bone anabolic reagents to enhance healing of tendon to bone. Journal of Cellular Biochemistry, 119 (7), 5715-5724. doi: 10.1002/jcb.26755 |
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2018 Journal Article Retention of the structure and function of heparan sulfate biomaterials after gamma irradiationSmith, Raymond A. A., Chua, R. J. E., Carnachan, Susan M., Tan, Clarissa L. L., Sims, Ian M., Hinkley, Simon F. R., Nurcombe, Victor and Cool, Simon M. (2018). Retention of the structure and function of heparan sulfate biomaterials after gamma irradiation. Tissue Engineering - Part A, 24 (9-10), 729-739. doi: 10.1089/ten.tea.2017.0263 |
