2015 Conference Publication High-throughput microfluidic screening of human mesenchymal Stem Cell proliferative responses to FGF-2 and heparan sulfatesTitmarsh, D., Glass, N., Nurcombe, V., Cooper-White, J. and Cool, S. (2015). High-throughput microfluidic screening of human mesenchymal Stem Cell proliferative responses to FGF-2 and heparan sulfates. 4th TERMIS World Congress, Boston, MA USA, 8-11 September 2015. New Rochelle, NY USA: Mary Ann Liebert. |
2015 Journal Article Establishing criteria for human mesenchymal stem cell potencySamsonraj, Rebekah M., Rai, Bina, Sathiyanathan, Padmapriya, Puan, Kia Joo, Rötzschke, Olaf, Hui, James H., Raghunath, Michael, Stanton, Lawrence W., Nurcombe, Victor and Cool, Simon M. (2015). Establishing criteria for human mesenchymal stem cell potency. Stem Cells, 33 (6), 1878-1891. doi: 10.1002/stem.1982 |
2014 Journal Article Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicityOkolicsanyi, Rachel K., Van Wijnen, Andre J., Cool, Simon M., Stein, Gary S., Griffiths, Lyn R. and Haupt, Larisa M. (2014). Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity. Journal of Cellular Biochemistry, 115 (5), 967-976. doi: 10.1002/jcb.24746 |
2014 Journal Article Engineering a vascular endothelial growth factor 165-binding heparan sulfate for vascular therapyWang, Chunming, Poon, Selina, Murali, Sadasivam, Koo, Chuay-Yeng, Bell, Tracey J., Hinkley, Simon F., Yeong, Huiqing, Bhakoo, Kishore, Nurcombe, Victor and Cool, Simon M. (2014). Engineering a vascular endothelial growth factor 165-binding heparan sulfate for vascular therapy. Biomaterials, 35 (25), 6776-6786. doi: 10.1016/j.biomaterials.2014.04.084 |
2014 Journal Article New strategies for cartilage regeneration exploiting selected glycosaminoglycans to enhance cell fate determinationAyerst, Bethanie I., Day, Anthony J., Nurcombe, Victor, Cool, Simon M. and Merry, Catherine L.R. (2014). New strategies for cartilage regeneration exploiting selected glycosaminoglycans to enhance cell fate determination. Biochemical Society Transactions, 42 (3), 703-709. doi: 10.1042/BST20140031 |
2013 Journal Article FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1Dombrowski, Christian, Helledie, Torben, Ling, Ling, Grünert, Martin, Canning, Claire A., Jones, C. Michael, Hui, James H., Nurcombe, Victor, Van Wijnen, Andre J. and Cool, Simon M. (2013). FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1. Stem Cells, 31 (12), 2724-2736. doi: 10.1002/stem.1514 |
2013 Journal Article MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaVan Der Deen, Margaretha, Taipaleenmäki, Hanna, Zhang, Ying, Teplyuk, Nadiya M., Gupta, Anurag, Cinghu, Senthilkumar, Shogren, Kristen, Maran, Avudaiappan, Yaszemski, Michael J., Ling, Ling, Cool, Simon M., Leong, David T., Dierkes, Christian, Zustin, Jozef, Salto-Tellez, Manuel, Ito, Yoshiaki, Bae, Suk-Chul, Zielenska, Maria, Squire, Jeremy A., Lian, Jane B., Stein, Janet L., Zambetti, Gerard P., Jones, Stephen N., Galindo, Mario, Hesse, Eric, Stein, Gary S. and Van Wijnen, Andre J. (2013). MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma. Journal of Biological Chemistry, 288 (29), 21307-21319. doi: 10.1074/jbc.M112.445890 |
2013 Journal Article Affinity-selected heparan sulfate for bone repairMurali, S., Rai, B., Dombrowski, C., Lee, J. L.J., Lim, Z. X.H., Bramono, D. S., Ling, L., Bell, T., Hinkley, S., Nathan, S. S., Hui, J. H., Wong, H. K., Nurcombe, V. and Cool, S. M. (2013). Affinity-selected heparan sulfate for bone repair. Biomaterials, 34 (22), 5594-5605. doi: 10.1016/j.biomaterials.2013.04.017 |
2013 Journal Article Telomere length analysis of human mesenchymal stem cells by quantitative PCRSamsonraj, Rebekah M., Raghunath, Michael, Hui, James H., Ling, Ling, Nurcombe, Victor and Cool, Simon M. (2013). Telomere length analysis of human mesenchymal stem cells by quantitative PCR. Gene, 519 (2), 348-355. doi: 10.1016/j.gene.2013.01.039 |
2013 Book Chapter Heparanated surfacesNurcombe, Victor, Birch, William R. and Cool, Simon M. (2013). Heparanated surfaces. Handbook of Biofunctional Surfaces. (pp. 617-638) Boca Raton, FL United States: Pan Stanford Publishing. |
2013 Journal Article The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formationBhakta, Gajadhar, Lim, Zophia X.H., Rai, Bina, Lin, Tingxuan, Hui, James H., Prestwich, Glenn D., Van Wijnen, Andre J., Nurcombe, Victor and Cool, Simon M. (2013). The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formation. Acta Biomaterialia, 9 (11), 9098-9106. doi: 10.1016/j.actbio.2013.07.008 |
2012 Journal Article Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2Bhakta, Gajadhar, Rai, Bina, Lim, Zophia X.H., Hui, James H., Stein, Gary S., van Wijnen, Andre J., Nurcombe, Victor, Prestwich, Glenn D. and Cool, Simon M. (2012). Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2. Biomaterials, 33 (26), 6113-6122. doi: 10.1016/j.biomaterials.2012.05.030 |
2012 Journal Article Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrowHelledie, Torben, Dombrowski, Christian, Rai, Bina, Lim, Zophia X.H., Hin, Ian Lee Hock, Rider, David A., Stein, Gary S., Hong, Wanjin, Van Wijnen, Andre J., Hui, James H., Nurcombe, Victor and Cool, Simon M. (2012). Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow. Stem Cells and Development, 21 (11), 1897-1910. doi: 10.1089/scd.2011.0367 |
2012 Journal Article Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfacesHeng, Boon Chin, Li, Jian, Chen, Allen Kuan-Liang, Reuveny, Shaul, Cool, Simon M., Birch, William R. and Oh, Steve Kah-Weng (2012). Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfaces. Stem Cells and Development, 21 (10), 1701-1715. doi: 10.1089/scd.2011.0509 |
2012 Journal Article Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2)Bramono, Diah S., Murali, Sadasivam, Rai, Bina, Ling, Ling, Poh, Wei Theng, Lim, Zophia Xuehui, Stein, Gary S., Nurcombe, Victor, van Wijnen, Andre J. and Cool, Simon M. (2012). Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2). Bone, 50 (4), 954-964. doi: 10.1016/j.bone.2011.12.013 |
2011 Journal Article The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (ɛ-caprolactone)/collagen fibers and hyaluronic acid hydrogelEkaputra, Andrew K., Prestwich, Glenn D., Cool, Simon M. and Hutmacher, Dietmar W. (2011). The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (ɛ-caprolactone)/collagen fibers and hyaluronic acid hydrogel. Biomaterials, 32 (32), 8108-8117. doi: 10.1016/j.biomaterials.2011.07.022 |
2011 Journal Article Multifunctional silica nanoparticles with potentials of imaging and gene deliveryBhakta, Gajadhar, Sharma, Rakesh Kumar, Gupta, Nikesh, Cool, Simon, Nurcombe, Victor and Maitra, Amarnath (2011). Multifunctional silica nanoparticles with potentials of imaging and gene delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 7 (4), 472-479. doi: 10.1016/j.nano.2010.12.008 |
2011 Journal Article The effect of human bone marrow stroma-derived heparan sulfate on the Ex vivo expansion of human cord blood hematopoietic stem cellsBramono, Diah S., Rider, David A., Murali, Sadasivam, Nurcombe, Victor and Cool, Simon M. (2011). The effect of human bone marrow stroma-derived heparan sulfate on the Ex vivo expansion of human cord blood hematopoietic stem cells. Pharmaceutical Research, 28 (6), 1385-1394. doi: 10.1007/s11095-010-0352-y |
2011 Journal Article Comparative assessment of the effects of gender-specific heparan sulfates on mesenchymal stem cellsMurali, Sadasivam, Leong, Denise F. M., Lee, Jaslyn J. L., Cool, Simon M. and Nurcombe, Victor (2011). Comparative assessment of the effects of gender-specific heparan sulfates on mesenchymal stem cells. Journal of Biological Chemistry, 286 (20), 17755-17765. doi: 10.1074/jbc.M110.148874 |
2011 Journal Article Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cellsYap, Lynn Y.W., Li, Jian, Phang, In Yee, Ong, Lay Ting, Ow, Jo'An Zhu-En, Goh, James C.H., Nurcombe, Victor, Hobley, Jonathan, Choo, Andre B.H., Oh, Steve K.W., Cool, Simon M. and Birch, William R. (2011). Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cells. Tissue Engineering - Part C: Methods, 17 (2), 193-207. doi: 10.1089/ten.tec.2010.0328 |