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2025 Journal Article JAK inhibition and axial spondyloarthritis: new steps on the path to understanding pathophysiologyCiccia, Francesco, Mcgonagle, Dennis, Thomas, Ranjeny, Marzo-Ortega, Helena, Martin, David A., Yndestad, Arne and Volkov, Mikhail (2025). JAK inhibition and axial spondyloarthritis: new steps on the path to understanding pathophysiology. Frontiers in Immunology, 16 1488357, 1-11. doi: 10.3389/fimmu.2025.1488357 |
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2025 Journal Article Comparative study of management strategies for immune checkpoint inhibitor-induced inflammatory arthritis: rheumatologists versus oncologistsYoon, Jang S., Zhao, Frances, Masood, Hafsa, De Silva, Ravini, Binns, Jessie, Atkinson, Victoria, Thomas, Ranjeny and Terrill, Matthew (2025). Comparative study of management strategies for immune checkpoint inhibitor-induced inflammatory arthritis: rheumatologists versus oncologists. Internal Medicine Journal, 55 (3), 426-434. doi: 10.1111/imj.16629 |
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2025 Journal Article Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful diseaseDeane, Kevin D, Holers, V Michael, Emery, Paul, Mankia, Kulveer, El Gabalawy, Hani, Sparks, Jeffrey A, Costenbader, Karen H, Schett, Georg, van der Helm-van Mil, Annette, van Schaardenburg, Dirkjan, Thomas, Ranjeny and Cope, Andrew P (2025). Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease. Annals of the Rheumatic Diseases, 84 (1) 224211, 14-28. doi: 10.1136/ard-2023-224211 |
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2024 Journal Article Exploring the association between circulating endothelial protein C receptor and disease activity of rheumatoid arthritis in a pilot studyXue, Meilang, Lin, Haiyan, Lynch, Tom, Bereza-Malcolm, Lara, Sinnathurai, Premarani, Thomas, Ranjeny, Keen, Helen, Hill, Catherine, Lester, Susan, Wechalekar, Mihir and March, Lyn (2024). Exploring the association between circulating endothelial protein C receptor and disease activity of rheumatoid arthritis in a pilot study. Rheumatology Advances in Practice, 8 (3) rkae096, rkae096. doi: 10.1093/rap/rkae096 |
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2024 Journal Article A novel method to monitor rheumatoid arthritis prevalence using hospital and medication databasesKoller-Smith, Louise, Mehdi, Ahmed, March, Lyn, Tooth, Leigh, Mishra, Gita D. and Thomas, Ranjeny (2024). A novel method to monitor rheumatoid arthritis prevalence using hospital and medication databases. Arthritis Research and Therapy, 26 (1) 133, 133. doi: 10.1186/s13075-024-03366-x |
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2024 Journal Article CD8<sup>+</sup>tissue-resident memory T cells are expanded in primary Sjögren’s disease and can be therapeutically targeted by CD103 blockadeMauro, Daniele, Lin, Xiang, Pontarini, Elena, Wehr, Pascale, Guggino, Giuliana, Tang, Yuan, Deng, Chong, Gandolfo, Saviana, Xiao, Fan, Rui, Ke, Huang, Enyu, Tian, Jie, Raimondo, Stefania, Rischmueller, Maureen, Boroky, Jane, Downie-Doyle, Sarah, Nel, Hendrik, Baz-Morelli, Adriana, Hsu, Arthur, Maraskovsky, Eugene, Barr, Adele, Hemon, Patrice, Chatzis, Loukas, Boschetti, Ciro Emiliano, Colella, Giuseppe, Alessandro, Riccardo, Rizzo, Aroldo, Pers, Jacques-Olivier, Bombardieri, Michele ... Ciccia, Francesco (2024). CD8+tissue-resident memory T cells are expanded in primary Sjögren’s disease and can be therapeutically targeted by CD103 blockade. Annals of the Rheumatic Diseases, 83 (10), 1-13. doi: 10.1136/ard-2023-225069 |
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2024 Journal Article IDH mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activationHong, Lih En, Wechalekar, Mihir D., Kutyna, Monika M, Small, Annabelle, Lim, Kelly, Thompson-Peach, Chloe AL, Li, Joule J, Chhetri, Rakchha, Scott, Hamish S, Brown, Anna L, Hahn, Christopher N, Yeung, David T, Sajid, Salvia, Robinson, Nirmal, Thomas, Ranjeny, Branford, Susan, D'Andrea, Richard J. J, Samaraweera, Saumya E. E, Patnaik, Mrinal M., Proudman, Susanna, Thomas, Daniel, Kok, Chung Hoow, Shah, Mithun Vinod and Hiwase, Devendra K. (2024). IDH mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation. Blood Journal, 143 (18), 1873-1877. doi: 10.1182/blood.2023023593 |
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2024 Journal Article Dendritic cells and antigen-specific immunotherapy in autoimmune rheumatic diseasesCai, Benjamin and Thomas, Ranjeny (2024). Dendritic cells and antigen-specific immunotherapy in autoimmune rheumatic diseases. Best Practice and Research: Clinical Rheumatology, 38 (2) 101940, 101940. doi: 10.1016/j.berh.2024.101940 |
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2024 Journal Article Immune tolerance of citrullinated peptidesThomas, Ranjeny and Robinson, William H. (2024). Immune tolerance of citrullinated peptides. Nature Reviews Rheumatology, 20 (3), 141-142. doi: 10.1038/s41584-024-01081-0 |
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2024 Journal Article Liposomal delivery of self‐peptide and calcitriol as tolerogenic immunotherapy in rheumatoid arthritis: an exploration using sensory scienceHee, Jia Yi, Cai, Benjamin and Thomas, Ranjeny (2024). Liposomal delivery of self‐peptide and calcitriol as tolerogenic immunotherapy in rheumatoid arthritis: an exploration using sensory science. Immunology & Cell Biology, 102 (5), 353-357. doi: 10.1111/imcb.12719 |
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2023 Journal Article Reinforcing the Checkpoint in Rheumatoid ArthritisGravallese, Ellen M. and Thomas, Ranjeny (2023). Reinforcing the Checkpoint in Rheumatoid Arthritis. The New England journal of medicine, 388 (20), 1905-1907. doi: 10.1056/NEJMe2300734 |
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2023 Journal Article Antigen specific immunotherapy to restore antigen-specific tolerance in type 1 diabetes and Graves’ diseaseZala, Aakansha and Thomas, Ranjeny (2023). Antigen specific immunotherapy to restore antigen-specific tolerance in type 1 diabetes and Graves’ disease. Clinical and Experimental Immunology, 211 (2), 164-175. doi: 10.1093/cei/uxac115 |
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2023 Journal Article Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathyBhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara Rao, Mehdi, Ahmed M., Bergot, Anne-Sophie, Simone, Davide, El-Kurdi, Marya, Garrido-Mesa, Jose, Cai, Cheng Bang Benjamin, Cameron, Amy J., Hanson, Aimee L., Nel, Hendrik J., Kenna, Tony, Leo, Paul, Rehaume, Linda, Brown, Matthew A., Ciccia, Francesco and Thomas, Ranjeny (2023). Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. Clinical Immunology, 247 109220, 1-14. doi: 10.1016/j.clim.2022.109220 |
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2022 Journal Article Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associationsMuralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Syeda Farah, Ali, Rubbiya A., Chandra, Janin, Frazer, Ian H., Thomas, Ranjeny and Mehdi, Ahmed M. (2022). Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations. Scientific Reports, 12 (1) 18710, 1-19. doi: 10.1038/s41598-022-21988-6 |
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2022 Journal Article Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritisSonigra, Amee, Nel, Hendrik J., Wehr, Pascale, Ramnoruth, Nishta, Patel, Swati, van Schie, Karin A., Bladen, Maxwell W., Mehdi, Ahmed M., Tesiram, Joanne, Talekar, Meghna, Rossjohn, Jamie, Reid, Hugh H., Stuurman, Frederik E., Roberts, Helen, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Becart, Stephane, Toes, Rene E.M., Scherer, Hans Ulrich, Lê Cao, Kim-Anh, Campbell, Kim and Thomas, Ranjeny (2022). Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis. JCI Insight, 7 (20) e160964, 1-18. doi: 10.1172/jci.insight.160964 |
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2022 Journal Article Global epidemiology of rheumatoid arthritisFinckh, Axel, Gilbert, Benoît, Hodkinson, Bridget, Bae, Sang-Cheol, Thomas, Ranjeny, Deane, Kevin D., Alpizar-Rodriguez, Deshiré and Lauper, Kim (2022). Global epidemiology of rheumatoid arthritis. Nature Reviews Rheumatology, 18 (10), 591-602. doi: 10.1038/s41584-022-00827-y |
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2022 Journal Article Immune tolerance therapies for autoimmune diseases: shifting the goalpost to cureSharkey, Patrick and Thomas, Ranjeny (2022). Immune tolerance therapies for autoimmune diseases: shifting the goalpost to cure. Current Opinion in Pharmacology, 65 102242, 102242. doi: 10.1016/j.coph.2022.102242 |
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2022 Journal Article Secreted NF-κB suppressive microbial metabolites modulate gut inflammationGiri, Rabina, Hoedt, Emily C., Khushi, Shamsunnahar, Salim, Angela A., Bergot, Anne-Sophie, Schreiber, Veronika, Thomas, Ranjeny, McGuckin, Michael A., Florin, Timothy H., Morrison, Mark, Capon, Robert J., Ó Cuív, Páraic and Begun, Jakob (2022). Secreted NF-κB suppressive microbial metabolites modulate gut inflammation. Cell Reports, 39 (2) 110646, 110646. doi: 10.1016/j.celrep.2022.110646 |
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2022 Journal Article Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer stainingPatel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh H., Campbell, Kim, Nel, Hendrik J. and Thomas, Ranjeny (2022). Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining. Clinical and Experimental Immunology, 207 (1), 72-83. doi: 10.1093/cei/uxab008 |
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2022 Journal Article Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitopeBuckle, Irina, Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Zhang, Vivian, Talekar, Meghna, Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2022). Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope. Immunology and Cell Biology, 100 (1), 33-48. doi: 10.1111/imcb.12506 |