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2021 Journal Article IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetesGreenbaum, Carla J., Serti, Elisavet, Lambert, Katharina, Weiner, Lia J., Kanaparthi, Sai, Lord, Sandra, Gitelman, Stephen E., Wilson, Darrell M., Gaglia, Jason L., Griffin, Kurt J., Russell, William E., Raskin, Philip, Moran, Antoinette, Willi, Steven M., Tsalikian, Eva, DiMeglio, Linda A., Herold, Kevan C., Moore, Wayne V., Goland, Robin, Harris, Mark, Craig, Maria E., Schatz, Desmond A., Baidal, David A., Rodriguez, Henry, Utzschneider, Kristina M., Nel, Hendrik J., Soppe, Carol L., Boyle, Karen D., Cerosaletti, Karen ... Sanda, Srinath (2021). IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight, 6 (21) e150074. doi: 10.1172/jci.insight.150074 |
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2021 Journal Article Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registrySparks, Jeffrey A, Wallace, Zachary S, Seet, Andrea M, Gianfrancesco, Milena A, Izadi, Zara, Hyrich, Kimme L, Strangfeld, Anja, Gossec, Laure, Carmona, Loreto, Mateus, Elsa F, Lawson-Tovey, Saskia, Trupin, Laura, Rush, Stephanie, Katz, Patricia, Schmajuk, Gabriela, Jacobsohn, Lindsay, Wise, Leanna, Gilbert, Emily L, Duarte-Garciá, Ali, Valenzuela-Almada, Maria O, Pons-Estel, Guillermo J, Isnardi, Carolina A, Berbotto, Guillermo A, Hsu, Tiffany Y-T, D'Silva, Kristin M, Patel, Naomi J, Kearsley-Fleet, Lianne, Schäfer, Martin, Ribeiro, Sandra Lúcia Euzébio ... Yazdany, Jinoos (2021). Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry. Annals of the Rheumatic Diseases, 80 (9), 1137-1146. doi: 10.1136/annrheumdis-2021-220418 |
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2021 Journal Article Preclinical models of arthritis for studying immunotherapy and immune toleranceMeehan, Gavin R., Thomas, Ranjeny, Al Khabouri, Shaima, Wehr, Pascale, Hilkens, Catharien M.U., Wraith, David C., Sieghart, Daniela, Bonelli, Michael, Nagy, György, Garside, Paul, Tough, David F., Lewis, Huw D. and Brewer, James M. (2021). Preclinical models of arthritis for studying immunotherapy and immune tolerance. Annals of the Rheumatic Diseases, 80 (10), 1268-1277. doi: 10.1136/annrheumdis-2021-220043 |
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2021 Journal Article Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetesThomas, Ranjeny, Carballido, José M., Wesley, Johnna D. and Ahmed, Simi T. (2021). Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetes. Frontiers in Immunology, 12 730414, 730414. doi: 10.3389/fimmu.2021.730414 |
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2021 Journal Article Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosusRobinson, Sean and Thomas, Ranjeny (2021). Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus. Frontiers in Immunology, 12 654701, 654701. doi: 10.3389/fimmu.2021.654701 |
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2021 Journal Article Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG miceRomand, Xavier, Liu, Xiao, Rahman, M. Arifur, Bhuyan, Zaied Ahmed, Douillard, Claire, Arora Kedia, Reena, Stone, Nathan, Roest, Dominique, Chew, Zi Huai, Cameron, Amy J., Rehaume, Linda M., Bozon, Aurélie, Habib, Mohammed, Armitage, Charles W., Nguyen, Minh Vu Chuong, Favier, Bertrand, Beagley, Kenneth, Maurin, Max, Gaudin, Philippe, Thomas, Ranjeny, Wells, Timothy J. and Baillet, Athan (2021). Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice. Arthritis and Rheumatology, 73 (7) art.41653, 1200-1210. doi: 10.1002/art.41653 |
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2021 Journal Article Ankylosing spondylitis: an autoimmune or autoinflammatory disease?Mauro, Daniele, Thomas, Ranjeny, Guggino, Giuliana, Lories, Rik, Brown, Matthew A. and Ciccia, Francesco (2021). Ankylosing spondylitis: an autoimmune or autoinflammatory disease?. Nature Reviews Rheumatology, 17 (7), 387-404. doi: 10.1038/s41584-021-00625-y |
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2021 Journal Article Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosisGuggino, Giuliana, Mauro, Daniele, Rizzo, Aroldo, Alessandro, Riccardo, Raimondo, Stefania, Bergot, Anne-Sophie, Rahman, M Arifur, Ellis, Jonathan J., Milling, Simon, Lories, Rik, Elewaut, Dirk, Brown, Matthew A., Thomas, Ranjeny and Ciccia, Francesco (2021). Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis. Arthritis and Rheumatology, 73 (7) art.41644, 1189-1199. doi: 10.1002/art.41644 |
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2021 Journal Article A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectivesBenham, Helen, Chiu, Hedva, Tesiram, Joanne, Mehdi, Ahmed, Landsberg, Peter, Grosman, Sergei, Harrison, Andrew, Nash, Peter, Thomas, Ranjeny, Langbecker, Danette and Van Driel, Mieke (2021). A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives. International Journal of Rheumatic Diseases, 24 (3), 355-363. doi: 10.1111/1756-185x.14051 |
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2021 Journal Article Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in miceMoentadj, Rabia, Wang, Yiwen, Bowerman, Kate, Rehaume, Linda, Nel, Hendrik, O Cuiv, Paraic, Stephens, Juliette, Baharom, Amalina, Maradana, Muralidhara, Lakis, Vanessa, Morrison, Mark, Wells, Timothy, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2021). Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice. Annals of the Rheumatic Diseases, 80 (5) annrheumdis-2020-219009, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219009 |
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2021 Journal Article CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetesNarsale, Aditi, Lam, Breanna, Moya, Rosa, Lu, TingTing, Mandelli, Alessandra, Gotuzzo, Irene, Pessina, Benedetta, Giamporcaro, Gianmaria, Geoffrey, Rhonda, Buchanan, Kerry, Harris, Mark, Bergot, Anne-Sophie, Thomas, Ranjeny, Hessner, Martin J., Battaglia, Manuela, Serti, Elisavet and Davies, Joanna D. (2021). CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. JCI Insight, 6 (2) e136114. doi: 10.1172/jci.insight.136114 |
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2021 Journal Article Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ riskKoller‐Smith, Louise, Mehdi, Ahmed M., March, Lyn, Tooth, Leigh, Mishra, Gita and Thomas, Ranjeny (2021). Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ risk. Internal Medicine Journal, 52 (5), 711-716. doi: 10.1111/imj.15537 |
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2021 Journal Article Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetesMusthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315 |
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2020 Journal Article Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetesMusthaffa, Yassmin, Nel, Hendrik J., Ramnoruth, Nishta, Patel, Swati, Hamilton-Williams, Emma E., Harris, Mark and Thomas, Ranjeny (2020). Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetes. Frontiers in Immunology, 11 587469, 587469. doi: 10.3389/fimmu.2020.587469 |
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2020 Journal Article Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapyNel, Hendrik J., Malmström, Vivianne, Wraith, David C. and Thomas, Ranjeny (2020). Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy. The Lancet Rheumatology, 2 (11), e712-e723. doi: 10.1016/S2665-9913(20)30344-1 |
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2020 Journal Article Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cellsChan, Jack D., Scheidt, Bianca, Zeng, Bijun, Oliver, Amanda J., Davey, Ashleigh S., Ali, Aesha I., Thomas, Ranjeny, Trapani, Joseph A., Darcy, Phillip K., Kershaw, Michael H., Dolcetti, Riccardo and Slaney, Clare Y. (2020). Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells. Clinical and Translational Immunology, 9 (7) e1157, e1157. doi: 10.1002/cti2.1157 |
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2020 Journal Article The microbiome and rheumatoid arthritisBergot, Anne-Sophie, Giri, Rabina and Thomas, Ranjeny (2020). The microbiome and rheumatoid arthritis. Best Practice and Research: Clinical Rheumatology, 33 (6) 101497, 101497. doi: 10.1016/j.berh.2020.101497 |
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2020 Journal Article T‐cell receptor immunosequencing reveals altered repertoire diversity and disease‐associated clonal expansions in ankylosing spondylitis patientsHanson, Aimee L., Nel, Hendrik J., Bradbury, Linda, Phipps, Julie, Thomas, Ranjeny, Lê Cao, Kim‐Anh, Kenna, Tony J. and Brown, Matthew A. (2020). T‐cell receptor immunosequencing reveals altered repertoire diversity and disease‐associated clonal expansions in ankylosing spondylitis patients. Arthritis and Rheumatology, 72 (8) art.41252, 1289-1302. doi: 10.1002/art.41252 |
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2020 Journal Article Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating AntibodiesChew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019 |
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2020 Journal Article RelB suppresses type I Interferon signaling in dendritic cellsSaha, Irene, Jaiswal, Hemant, Mishra, Richa, Nel, Hendrik J., Schreuder, Jaring, Kaushik, Monika, Singh Chauhan, Kuldeep, Singh Rawat, Bhupendra, Thomas, Ranjeny, Naik, Shalin, Kumar, Himanshu and Tailor, Prafullakumar (2020). RelB suppresses type I Interferon signaling in dendritic cells. Cellular Immunology, 349 104043, 104043. doi: 10.1016/j.cellimm.2020.104043 |
