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2014

Journal Article

Dendritic cells as targets or therapeutics in rheumatic autoimmune disease

Thomas, Ranjeny (2014). Dendritic cells as targets or therapeutics in rheumatic autoimmune disease. Current Opinion in Rheumatology, 26 (2), 211-218. doi: 10.1097/BOR.0000000000000032

Dendritic cells as targets or therapeutics in rheumatic autoimmune disease

2014

Journal Article

Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis

Law, Soi-Chen, Benham, Helen, Reid, Hugh H., Rossjohn, Jamie and Thomas, Ranjeny (2014). Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis. Rheumatic Disease Clinics of North America, 40 (4), 735-752. doi: 10.1016/j.rdc.2014.07.015

Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis

2013

Journal Article

Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly

Zeng, B. J., Chuan, Y. P., O’Sullivan, B., Caminschi, I., Lahoud, M. H., Thomas, R. and Middelberg, A. P. J. (2013). Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly. Small, 9 (22), 3736-3742. doi: 10.1002/smll.201300078

Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly

2013

Journal Article

RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface

Thomas, Ranjeny (2013). RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface. Immunology and Cell Biology, 91 (9), 543-544. doi: 10.1038/icb.2013.51

RelB, AhR and dendritic cells RelB and the aryl hydrocarbon receptor: dendritic cell tolerance at the epithelial interface

2013

Journal Article

Th17 and Th22 cells in psoriatic arthritis and psoriasis

Benham, Helen, Norris, Paul, Goodall, Jane, Wechalekar, Mihir D., FitzGerald, Oliver, Szentpetery, Agnes, Smith, Malcolm, Thomas, Ranjeny and Gaston, Hill (2013). Th17 and Th22 cells in psoriatic arthritis and psoriasis. Arthritis Research and Therapy, 15 (5) R136. doi: 10.1186/ar4317

Th17 and Th22 cells in psoriatic arthritis and psoriasis

2013

Journal Article

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

2013

Journal Article

Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges

Thomas, Ranjeny (2013). Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges. Arthritis Research & Therapy, 15 (6) 128. doi: 10.1186/ar4420

Synovial fluid CD1c(+) myeloid dendritic cells - the inflammatory picture emerges

2013

Journal Article

Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort

White, Douglas, Pahau, Helen, Duggan, Emily, Paul, Sanjoy and Thomas, Ranjeny (2013). Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort. BMJ Open, 3 (7) e003083, e003083.1-e003083.10. doi: 10.1136/bmjopen-2013-003083

Trajectory of intensive treat-to-target disease modifying drug regimen in an observational study of an early rheumatoid arthritis cohort

2013

Journal Article

Targeted delivery of curcumin for treating type 2 diabetes

Maradana, Muralidhara Rao, Thomas, Ranjeny and O'Sullivan, Brendan J. (2013). Targeted delivery of curcumin for treating type 2 diabetes. Molecular Nutrition and Food Research, 57 (9), 1550-1556. doi: 10.1002/mnfr.201200791

Targeted delivery of curcumin for treating type 2 diabetes

2013

Journal Article

Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis

Thomas, Ranjeny (2013). Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis. Arthritis Research & Therapy, 15 (1) 204, 204.1-204.10. doi: 10.1186/ar4130

Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis

2012

Journal Article

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

Law, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012). T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 (3) R118, R118.1-R118.12. doi: 10.1186/ar3848

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

2012

Journal Article

Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis

Kenna, Tony J., Davidson, Stuart I., Duan, Ran, Bradbury, Linda A., McFarlane, Janelle, Smith, Malcolm, Weedon, Helen, Street, Shayna, Thomas, Ranjeny, Thomas, Gethin P. and Brown, Matthew A. (2012). Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis. Arthritis and Rheumatism, 64 (5), 1420-1429. doi: 10.1002/art.33507

Enrichment of circulating IL-17-secreting IL-23 receptor-positive gamma-delta T cells in patients with active ankylosing spondylitis

2012

Journal Article

Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes

Irvine, Katharine M., Gallego, Patricia, An, Xiaoyu, Best, Shannon E., Thomas, Gethin, Wells, Christine, Harris, Mark, Cotterill, Andrew and Thomas, Ranjeny (2012). Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes. Diabetes, 61 (5), 1281-1290. doi: 10.2337/db11-1549

Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes

2012

Journal Article

Autoimmunity: innovation in pathogenesis and therapy

Thomas, Ranjeny (2012). Autoimmunity: innovation in pathogenesis and therapy. Immunology and Cell Biology, 90 (3), 255-255. doi: 10.1038/icb.2012.5

Autoimmunity: innovation in pathogenesis and therapy

2012

Journal Article

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

Sakaguchi, Shimon, Benham, Helen, Cope, Andrew P. and Thomas, Ranjeny (2012). T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man. Immunology and Cell Biology, 90 (3), 277-287. doi: 10.1038/icb.2012.4

T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man

2012

Journal Article

Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion

Chuan, Yap Pang, Zeng, Bi Yun, O'Sullivan, Brendan, Thomas, Ranjeny and Middelberg, Anton P. J. (2012). Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion. Journal of Colloid and Interface Science, 368 (1), 616-624. doi: 10.1016/j.jcis.2011.11.014

Co-delivery of antigen and a lipophilic anti-inflammatory drug to cells via a tailorable nanocarrier emulsion

2011

Journal Article

Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice

Yekollu, Suman Kumar, Thomas, Ranjeny and O'Sullivan, Brendan (2011). Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice. Diabetes, 60 (11), 2928-2938. doi: 10.2337/db11-0275

Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice

2011

Journal Article

Langerhans cells are precommitted to immune tolerance induction

Shklovskaya, Elena, O'Sullivan, Brendan J., Ng, Lai Guan, Roediger, Ben, Thomas, Ranjeny, Weninger, Wolfgang and de St Groth, Barbara Fazekas (2011). Langerhans cells are precommitted to immune tolerance induction. Proceedings of the National Academy of Sciences of the United States of America, 108 (44), 18049-18054. doi: 10.1073/pnas.1110076108

Langerhans cells are precommitted to immune tolerance induction

2011

Journal Article

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

O'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

2011

Journal Article

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis