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2017

Journal Article

What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training

Eley, Diann S., Jensen, Charmaine, Thomas, Ranjeny and Benham, Helen (2017). What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training. BMC Medical Education, 14 (242) 242, 242. doi: 10.1186/s12909-017-1081-2

What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training

2017

Journal Article

Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response

Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017). Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 (OCT) 1350, 1350. doi: 10.3389/fimmu.2017.01350

Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response

2017

Journal Article

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation

Nair, Prema M, Starkey, Malcolm R, Haw, Tatt Jhong, Ruscher, Roland, Liu, Gang, Maradana, Muralidhara R, Thomas, Ranjeny, O'Sullivan, Brendan J and Hansbro, Philip M (2017). RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology, 58 (3), 352-365. doi: 10.1165/rcmb.2017-0242OC

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation

2017

Journal Article

WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice

Gatica-Andrades, Marcela, Vagenas, Dimitrios, Kling, Jessica, Nguyen, Tam T. K., Benham, Helen, Thomas, Ranjeny, Korner, Heinrich, Venkatesh, Bala, Cohen, Jeremy and Blumenthal, Antje (2017). WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice. Blood Advances, 1 (16), 1274-1286. doi: 10.1182/bloodadvances.2017006163

WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice

2017

Journal Article

Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study

Videm, Vibeke, Thomas, Ranjeny, Brown, Matthew A. and Hoff, Mari (2017). Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study. Journal of Rheumatology, 44 (8), 1134-1141. doi: 10.3899/jrheum.161396

Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study

2017

Journal Article

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

2017

Journal Article

Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey

Ramos-Remus, Cesar, Barajas-Ochoa, Aldo, Ramirez-Gomez, Andrea, Castillo-Ortiz, Jose D., Brambila-Barba, Victor, Adebajo, Adewale O., Espinoza, Luis R., Aceves-Avila, Francisco J., Sanchez-Gonzalez, Jorge M., Boudersa, Nadia, Slimani, Samy, Ladjouze-Rezig, Aicha, Diaz, Monica P., Kirmayr, Karin I., Asnal, Cecilia A., Catoggio, Luis J., Citera, Gustavo, Casado, Gustavo C., Alvarez, Analia P., Pisoni, Cecilia N., Benavente, Emilio, Lopez-Cabanillas, Adriana, Baez, Roberto M., Pons-Estel, Bernardo A., Sacnun, Monica P., Cavallasca, Javier A., Paniego, Raul H., Proudman, Susanna M., Thomas, Ranjeny ... Villegas-Morales, Sol (2017). Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology, 36 (3), 485-497. doi: 10.1007/s10067-016-3481-9

Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey

2017

Journal Article

Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis

Lau, Max C., Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda A., Hollis, Kelly A., Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2017). Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 76 (1), 261-269. doi: 10.1136/annrheumdis-2015-208677

Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis

2016

Journal Article

Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features

Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458

Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features

2016

Journal Article

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

2016

Journal Article

Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice

James, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7

Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice

2016

Journal Article

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

Mutalik, Srinivas, Suthar, Neelam A., Managuli, Renuka S., Shetty, Pallavi K., Avadhani, Kiran, Kalthur, Guruprasad, Kulkarni, Raghavendra V. and Thomas, Ranjeny (2016). Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. International Journal of Biological Macromolecules, 86, 709-720. doi: 10.1016/j.ijbiomac.2015.11.092

Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin

2015

Journal Article

Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis

Cummins, L., Katikireddi, V. S., Shankaranarayana, S., Su, K. Y. C., Duggan, E., Videm, V., Pahau, H. and Thomas, R. (2015). Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis. Internal Medicine Journal, 45 (12), 1266-1273. doi: 10.1111/imj.12896

Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis

2015

Journal Article

Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17

Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes

2015

Journal Article

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

Koning, Frits, Thomas, Ranjeny, Rossjohn, Jamie and Toes, Rene E. (2015). Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nature Reviews Rheumatology, 11 (8), 450-461. doi: 10.1038/nrrheum.2015.59

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

2015

Journal Article

IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.

Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh A. K., Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M., Cao, Kim-Anh Le, Isaacs, John D. and Thomas, Ranjeny (2015). IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, 75 (2), 466-473. doi: 10.1136/annrheumdis-2014-205850

IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.

2015

Journal Article

Role of genetics in infection-associated arthritis

Benham, Helen, Robinson, Philip C., Baillet, Athan C., Rehaume, Linda M. and Thomas, Ranjeny (2015). Role of genetics in infection-associated arthritis. Best Practice and Research: Clinical Rheumatology, 29 (2), 213-225. doi: 10.1016/j.berh.2015.02.002

Role of genetics in infection-associated arthritis

2014

Journal Article

Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.

Videm, Vibeke, Cortes, Adrian, Thomas, Ranjeny and Brown, Matthew A. (2014). Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.. Journal of Rheumatology, 41 (10), 2041-2048. doi: 10.3899/jrheum.140353

Current smoking is a risk factor for incident ankylosing spondylitis – HUNT population-based Norwegian health study.

2014

Journal Article

Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT)

Pahau, Helen, Brown, Matthew A., Paul, Sanjoy, Thomas, Ranjeny and Videm, Vibeke (2014). Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT). Arthritis Research and Therapy, 16 (2) R85, 1-9. doi: 10.1186/ar4527

Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT)

2014

Journal Article

Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation

McNally, Alice, McNally, Michael, Galea, Ryan, Thomas, Ranjeny and Steptoe, Raymond J. (2014). Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation. PloS One, 9 (1) e85455, e85455. doi: 10.1371/journal.pone.0085455

Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+T-cell effector differentiation by IL-2 modulation