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2018 Journal Article Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient miceO'Sullivan, Brendan J., Yekollu, Suman, Ruscher, Roland, Mehdi, Ahmed M., Maradana, Muralidhara Rao, Chidgey, Ann P. and Thomas, Ranjeny (2018). Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice. Frontiers in Immunology, 9 (MAY) 1092, 1092. doi: 10.3389/fimmu.2018.01092 |
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2018 Journal Article Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol DevelopmentJansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny (2018). Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development. Frontiers in Immunology, 9 (JAN) 8, 1-10. doi: 10.3389/fimmu.2018.00008 |
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2018 Journal Article The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritisTing, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie (2018). The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. The Journal of Biological Chemistry, 293 (9), 3236-3251. doi: 10.1074/jbc.RA117.001013 |
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2018 Journal Article Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitisMaradana, Muralidhara Rao, Yekollu, Suman Kumar, Zeng, Bijun, Ellis, Jonathan, Clouston, Andrew, Miller, Gregory, Talekar, Meghna, Bhuyan, Zaied Ahmed, Mahadevaiah, Sachin, Powell, Elizabeth E., Irvine, Katharine M., Thomas, Ranjeny and O'Sullivan, Brendan John (2018). Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Metabolism: Clinical and Experimental, 78, 80-94. doi: 10.1016/j.metabol.2017.09.002 |
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2017 Journal Article What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist trainingEley, Diann S., Jensen, Charmaine, Thomas, Ranjeny and Benham, Helen (2017). What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training. BMC Medical Education, 14 (242) 242, 242. doi: 10.1186/s12909-017-1081-2 |
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2017 Journal Article Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune responseGarcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017). Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 (OCT) 1350, 1350. doi: 10.3389/fimmu.2017.01350 |
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2017 Journal Article RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway InflammationNair, Prema M, Starkey, Malcolm R, Haw, Tatt Jhong, Ruscher, Roland, Liu, Gang, Maradana, Muralidhara R, Thomas, Ranjeny, O'Sullivan, Brendan J and Hansbro, Philip M (2017). RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology, 58 (3), 352-365. doi: 10.1165/rcmb.2017-0242OC |
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2017 Journal Article WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in miceGatica-Andrades, Marcela, Vagenas, Dimitrios, Kling, Jessica, Nguyen, Tam T. K., Benham, Helen, Thomas, Ranjeny, Korner, Heinrich, Venkatesh, Bala, Cohen, Jeremy and Blumenthal, Antje (2017). WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice. Blood Advances, 1 (16), 1274-1286. doi: 10.1182/bloodadvances.2017006163 |
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2017 Journal Article Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health StudyVidem, Vibeke, Thomas, Ranjeny, Brown, Matthew A. and Hoff, Mari (2017). Self-reported diagnosis of rheumatoid arthritis or ankylosing spondylitis has low accuracy – data from the Nord-Trøndelag Health Study. Journal of Rheumatology, 44 (8), 1134-1141. doi: 10.3899/jrheum.161396 |
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2017 Journal Article Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cellsZhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152 |
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2017 Journal Article Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide surveyRamos-Remus, Cesar, Barajas-Ochoa, Aldo, Ramirez-Gomez, Andrea, Castillo-Ortiz, Jose D., Brambila-Barba, Victor, Adebajo, Adewale O., Espinoza, Luis R., Aceves-Avila, Francisco J., Sanchez-Gonzalez, Jorge M., Boudersa, Nadia, Slimani, Samy, Ladjouze-Rezig, Aicha, Diaz, Monica P., Kirmayr, Karin I., Asnal, Cecilia A., Catoggio, Luis J., Citera, Gustavo, Casado, Gustavo C., Alvarez, Analia P., Pisoni, Cecilia N., Benavente, Emilio, Lopez-Cabanillas, Adriana, Baez, Roberto M., Pons-Estel, Bernardo A., Sacnun, Monica P., Cavallasca, Javier A., Paniego, Raul H., Proudman, Susanna M., Thomas, Ranjeny ... Villegas-Morales, Sol (2017). Latitude gradient influences the age of onset of rheumatoid arthritis: a worldwide survey. Clinical Rheumatology, 36 (3), 485-497. doi: 10.1007/s10067-016-3481-9 |
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2017 Journal Article Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritisLau, Max C., Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda A., Hollis, Kelly A., Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2017). Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 76 (1), 261-269. doi: 10.1136/annrheumdis-2015-208677 |
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2016 Journal Article Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic featuresGarcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458 |
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2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
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2016 Journal Article Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcuminMutalik, Srinivas, Suthar, Neelam A., Managuli, Renuka S., Shetty, Pallavi K., Avadhani, Kiran, Kalthur, Guruprasad, Kulkarni, Raghavendra V. and Thomas, Ranjeny (2016). Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. International Journal of Biological Macromolecules, 86, 709-720. doi: 10.1016/j.ijbiomac.2015.11.092 |
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2016 Journal Article Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejectionColeman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418 |
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2015 Journal Article Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritisCummins, L., Katikireddi, V. S., Shankaranarayana, S., Su, K. Y. C., Duggan, E., Videm, V., Pahau, H. and Thomas, R. (2015). Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis. Internal Medicine Journal, 45 (12), 1266-1273. doi: 10.1111/imj.12896 |
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2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
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2015 Journal Article Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigensKoning, Frits, Thomas, Ranjeny, Rossjohn, Jamie and Toes, Rene E. (2015). Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nature Reviews Rheumatology, 11 (8), 450-461. doi: 10.1038/nrrheum.2015.59 |
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2015 Journal Article IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh A. K., Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M., Cao, Kim-Anh Le, Isaacs, John D. and Thomas, Ranjeny (2015). IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, 75 (2), 466-473. doi: 10.1136/annrheumdis-2014-205850 |
