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2013

Journal Article

Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment

Doig, Tamasin N., Hume, David A., Theocharidis, Thanasis, Goodlad, John R., Gregory, Christopher D. and Freeman, Tom C. (2013). Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment. BMC Genomics, 14 (1) 469. doi: 10.1186/1471-2164-14-469

Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment

2013

Journal Article

Comparative analysis of monocyte subsets in the pig

Fairbairn, Lynsey, Kapetanovic, Ronan, Beraldi, Dario, Sester, David P., Tuggle, Chris K., Archibald, Alan L. and Hume, David A. (2013). Comparative analysis of monocyte subsets in the pig. Journal of Immunology, 190 (12), 6389-6396. doi: 10.4049/jimmunol.1300365

Comparative analysis of monocyte subsets in the pig

Featured

2013

Journal Article

Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages

Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281

Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages

2013

Journal Article

Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli

Dave, Richa K., Dinger, Marcel E., Andrew, Megan, Askarian-Amiri, Marjan, Hume, David A. and Kellie, Stuart (2013). Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli. PLoS One, 8 (6) e68306, e68306.1-e68306.13. doi: 10.1371/journal.pone.0068306

Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli

2013

Journal Article

Erratum: Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis [Immunity 38 (2013) 79-91]

Yona, Simon, Kim, Ki-Wook, Wolf, Yochai, Mildner, Alexander, Varol, Diana, Breker, Michal, Strauss-Ayali, Dalit, Viukov, Sergey, Guilliams, Martin, Misharin, Alexander, Hume, DavidA., Perlman, Harris, Malissen, Bernard, Zelzer, Elazar and Jung, Steffen (2013). Erratum: Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis [Immunity 38 (2013) 79-91]. Immunity, 38 (5), 1073-1079. doi: 10.1016/j.immuni.2013.05.008

Erratum: Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis [Immunity 38 (2013) 79-91]

2013

Journal Article

Structural and functional annotation of the porcine immunome

Dawson, Harry D., Loveland, Jane E., Pascal, Geraldine, Gilbert, James G. R., Uenishi, Hirohide, Mann, Katherine M., Sang, Yongming, Zhang, Jie, Carvalho-Silva, Denise, Hunt, Toby, Hardy, Matthew, Hu, Zhiliang, Zhao, Shu-Hong, Anselmo, Anna, Shinkai, Hiroki, Chen, Celine, Badaoui, Bouabid, Berman, Daniel, Amid, Clara, Kay, Mike, Lloyd, David, Snow, Catherine, Morozumi, T., Cheng, Ryan Pei-Yen, Bystrom, Megan, Kapetanovic, Ronan, Schwartz, John C., Kataria, Ranjit, Astley, Matthew ... Tuggle, Christopher K. (2013). Structural and functional annotation of the porcine immunome. BMC Genomics, 14 (1) 332, 332.1-332.16. doi: 10.1186/1471-2164-14-332

Structural and functional annotation of the porcine immunome

2013

Journal Article

Can DCs be distinguished from macrophages by molecular signatures?

Hume, David A., Mabbott, Neil, Raza, Sobia and Freeman, Tom C. (2013). Can DCs be distinguished from macrophages by molecular signatures?. Nature Immunology, 14 (3), 187-189. doi: 10.1038/ni.2516

Can DCs be distinguished from macrophages by molecular signatures?

2013

Journal Article

Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34)

Gow, Deborah J., Garceau, Valerie, Pridans, Clare, Gow, Adam G., Simpson, Kerry E., Gunn-Moore, Danielle and Hume, David A. (2013). Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). Cytokine, 61 (2), 630-638. doi: 10.1016/j.cyto.2012.11.014

Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34)

2013

Journal Article

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

Yona, Simon, Kim, Ki-Wook, Wolf, Yochai, Mildner, Alexander, Varol, Diana, Breker, Michal, Strauss-Ayali, Dalit, Viukov, Sergey, Guilliams, Martin, Misharin, Alexander, Hume, David A., Perlman, Harris, Malissen, Bernard, Zelzer, Elazar and Jung, Steffen (2013). Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity, 38 (1), 79-91. doi: 10.1016/j.immuni.2012.12.001

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

2013

Journal Article

The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus

Sauter, Kristin A., Bouhlel, M. Amine, O'Neal, Julie, Sester, David P., Tagoh, Hiromi, Ingram, Richard M. I, Pridans, Clare, Bonifer, Constanze and Hume, David A. (2013). The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus. PLoS One, 8 (1) e54935, e54935. doi: 10.1371/journal.pone.0054935

The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus

2012

Journal Article

Cloning and expression of porcine Colony Stimulating Factor-1 (CSF-1) and Colony Stimulating Factor-1 Receptor (CSF-1R) and analysis of the species specificity of stimulation by CSF-1 and Interleukin 34

Gow, Deborah J., Garceau, Valerie, Kapetanovic, Ronan, Sester, David P., Fici, Greg J., Shelly, John A., Wilson, Thomas L. and Hume, David A. (2012). Cloning and expression of porcine Colony Stimulating Factor-1 (CSF-1) and Colony Stimulating Factor-1 Receptor (CSF-1R) and analysis of the species specificity of stimulation by CSF-1 and Interleukin 34. Cytokine, 60 (3), 793-805. doi: 10.1016/j.cyto.2012.08.008

Cloning and expression of porcine Colony Stimulating Factor-1 (CSF-1) and Colony Stimulating Factor-1 Receptor (CSF-1R) and analysis of the species specificity of stimulation by CSF-1 and Interleukin 34

2012

Journal Article

Prediction of altered 3 '-UTR miRNA-binding sites from RNA-seq data: the swine leukocyte antigen complex (SLA) as a model region

Ahanda, Marie-Laure Endale, Fritz, Eric R., Estelle, Jordi, Hu, Zhi-Liang, Madsen, Ole, Groenen, Martien A. M., Beraldi, Dario, Kapetanovic, Ronan, Hume, David A., Rowland, Robert R. R., Lunney, Joan K., Rogel-Gaillard, Claire, Reecy, James M. and Giuffra, Elisabetta (2012). Prediction of altered 3 '-UTR miRNA-binding sites from RNA-seq data: the swine leukocyte antigen complex (SLA) as a model region. Plos One, 7 (11) e48607, e48607.1-e48607.11. doi: 10.1371/journal.pone.0048607

Prediction of altered 3 '-UTR miRNA-binding sites from RNA-seq data: the swine leukocyte antigen complex (SLA) as a model region

2012

Journal Article

A gene expression atlas of the domestic pig

Freeman, Tom C., Ivens, Alasdair, Baillie, J. Kenneth, Beraldi, Dario, Barnett, Mark W., Dorward, David, Downing, Alison, Fairbairn, Lynsey, Kapetanovic, Ronan, Raza, Sobia, Tomoiu, Andru, Alberio, Ramiro, Wu, Chunlei, Su, Andrew I., Summers, Kim M., Tuggle, Christopher K., Archibald, Alan L. and Hume, David A. (2012). A gene expression atlas of the domestic pig. BMC Biology, 10 (9) 90. doi: 10.1186/1741-7007-10-90

A gene expression atlas of the domestic pig

2012

Journal Article

Plenary perspective: the complexity of constitutive and inducible gene expression in mononuclear phagocytes

Hume, David A. (2012). Plenary perspective: the complexity of constitutive and inducible gene expression in mononuclear phagocytes. Journal of Leukocyte Biology, 92 (3), 433-444. doi: 10.1189/jlb.0312166

Plenary perspective: the complexity of constitutive and inducible gene expression in mononuclear phagocytes

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2012

Journal Article

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

Schroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012). Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 (16), E944-E953. doi: 10.1073/pnas.1110156109

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

2012

Journal Article

IFITM3 restricts the morbidity and mortality associated with influenza

Everitt, Aaron R., Clare, Simon, Pertel, Thomas, John, Sinu P., Wash, Rachael S., Smith, Sarah E., Chin, Christopher R., Feeley, Eric M., Sims, Jennifer S., Adams, David J., Wise, Helen M., Kane, Leanne, Goulding, David, Digard, Paul, Anttila, Verneri, Baillie, J. Kenneth, Walsh, Tim S., Hume, David A., Palotie, Aarno, Xue, Yali, Colonna, Vincenza, Tyler-Smith, Chris, Dunning, Jake, Gordon, Stephen B., Smyth, Rosalind L., Openshaw, Peter J., Dougan, Gordon, Brass, Abraham L. and Kellam, Paul (2012). IFITM3 restricts the morbidity and mortality associated with influenza. Nature, 484 (7395), 519-523. doi: 10.1038/nature10921

IFITM3 restricts the morbidity and mortality associated with influenza

2012

Journal Article

Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide

Kapetanovic, Ronan, Fairbairn, Lynsey, Beraldi, Dario, Sester, David P., Archibald, Alan L., Tuggle, Christopher K. and Hume, David A. (2012). Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide. The Journal of Immunology, 188 (7), 3382-3394. doi: 10.4049/jimmunol.1102649

Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide

2012

Journal Article

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

Hume, David A. and MacDonald, Kelli P. A. (2012). Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling. Blood, 119 (8), 1810-1820. doi: 10.1182/blood-2011-09-379214

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

2011

Journal Article

Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages

Bradford, Barry M., Sester, David P., Hume, David A. and Mabbott, Neil A. (2011). Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages. Immunobiology, 216 (11), 1228-1237. doi: 10.1016/j.imbio.2011.08.006

Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages

2011

Journal Article

Macrophages.com: an on-line community resource for innate immunity research

Robert, Christelle, Lu, Xiang, Law, Andrew, Freeman, Tom C. and Hume, David A. (2011). Macrophages.com: an on-line community resource for innate immunity research. Immunobiology, 216 (11), 1203-1211. doi: 10.1016/j.imbio.2011.07.025

Macrophages.com: an on-line community resource for innate immunity research