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2008

Journal Article

The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans

WellsChristineA, Salvage-JonesJudithA, LiXin, HitchensKelly, ButcherSuzanne, MurrayRachaelZ, Beckhouse, Anthony G., LoYu-Lan-Sandra, ManzaneroSilvia, CobboldChristian, SchroderKate, MaBo, OrrSally, StewartLauren, LebusDaniel, SobieszczukPeter, HumeDavidA, StowJennifer, BlanchardHelen, AshmanRobertB, RRich and MHogan (2008). The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans. Journal of Immunology, 180 (11), 7404-7413. doi: 10.4049/jimmunol.180.11.7404

The macrophage-inducible C-type lectin, Mincle, is an essential component of the innate immune response to Candida albicans

2008

Journal Article

Increased TNF expression in CD43++ murine blood monocytes

Burke, Bernard, Ahmad, Rasheedah, Staples, Karl J., Snowden, Roger, Kadioglu, Aras, Frankenberger, Marion, Hume, David A. and Ziegler-Heitbrock, Loems (2008). Increased TNF expression in CD43++ murine blood monocytes. Immunology Letters, 118 (2), 142-147. doi: 10.1016/j.imlet.2008.03.012

Increased TNF expression in CD43++ murine blood monocytes

2008

Journal Article

The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene

Hume, David A., Sasmono, Tedjo, Himes, S. Roy, Sharma, Sudarshana M., Bronisz, Agnieszka, Constantin, Myrna, Ostrowski, Michael C. and Ross, Ian L. (2008). The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. The Journal of Immunology, 180 (10), 6733-6742. doi: 10.4049/jimmunol.180.10.6733

The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene

2008

Journal Article

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

Chang, Ming K., Raggatt, Liza-Jane, Alexander, Kylie A., Kuliwaba, Julia S., Fazzalari, Nicola L., Schroder, Kate, Maylin, Erin R., Ripoll, Vera M, Hume, David A. and Pettit, Allison R. (2008). Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo. The Journal of Immunology, 181 (2), 1232-1244. doi: 10.4049/jimmunol.181.2.1232

Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and In Vivo

2008

Journal Article

Expression analysis of G Protein-coupled receptors in mouse macrophages

Lattin, Jane E., Schroder, Kate, Su, Andrew I., Walker, John R., Zhang, Jie, Wiltshire, Tim, Saijo, Kaoru, Glass, Christopher K., Hume, David A., Kellie, Stuart and Sweet, Matthew J. (2008). Expression analysis of G Protein-coupled receptors in mouse macrophages. Immunome Research, 4 (5) 5, 5. doi: 10.1186/1745-7580-4-5

Expression analysis of G Protein-coupled receptors in mouse macrophages

2008

Journal Article

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

Pettit, Allison R., Hume, David A. and Raggatt, Liza-Jane (2008). Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats. Bone, 42 (4), 825-825. doi: 10.1016/j.bone.2007.12.217

Re: Structural and cellular differences between metaphyseal and diaphyseal periosteum in different-aged rats

2008

Journal Article

Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity

Lang, P., Van Harmelen, V., Kaaman, M., Parini, P., Carneheim, C., Cassady, A. I., Hume, D. A., Andersson, G. and Arner, P. (2008). Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity. PLoS One, 3 (3) e1713, e1713-e1713. doi: 10.1371/journal.pone.0001713

Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity

2008

Journal Article

Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice

Ovchinnikov, Dmitry A., van Zuylen, Wendy J. M., DeBats, Claire E. E., Alexander, Kylie A., Kellie, Stuart and Hume, David A. (2008). Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. Journal of Leukocyte Biology, 83 (2), 430-433. doi: 10.1189/jlb.0807585

Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice

2008

Journal Article

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

Ripoll, V. M, Meadows, N. A., Raggatt, L. J., Chang, M. K., Pettit, A. R., Cassady, A. I. and Hume, D. A. (2008). Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene, 413 (1-2), 32-41. doi: 10.1016/j.gene.2008.01.014

Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB

2008

Journal Article

The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis

Bonifer, Constanze and Hume, David A. (2008). The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis. Frontiers in Bioscience-Landmark, 13 (2), 549-560. doi: 10.2741/2700

The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis

2008

Journal Article

Differentiation and heterogeneity in the mononuclear phagocyte system

Hume, D. A. (2008). Differentiation and heterogeneity in the mononuclear phagocyte system. Mucosal Immunology, 1 (6), 432-441. doi: 10.1038/mi.2008.36

Differentiation and heterogeneity in the mononuclear phagocyte system

2008

Journal Article

Bring out your dead

Hume, David A. (2008). Bring out your dead. Nature Immunology, 9 (1), 12-14. doi: 10.1038/ni0108-12

Bring out your dead

2007

Journal Article

Systems biology of transcription control in macrophages

Ravasi, Timothy, Wells, Christine A. and Hume, David A. (2007). Systems biology of transcription control in macrophages. BioEssays, 29 (12), 1215-1226. doi: 10.1002/bies.20683

Systems biology of transcription control in macrophages

2007

Journal Article

Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients

McMorran, Brendan J., Patat, Severine A. Ouvry, Carlin, John B., Grimwood, Keith, Jones, Alun, Armstrong, David S., Galati, John C., Cooper, Peter J., Byrnes, Catherine A., Francis, Paul W., Robertson, Colin F., Hume, David A., Borchers, Christoph H., Wainwright, Claire E. and Wainwright, Brandon J. (2007). Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients. Clinical Chemistry, 53 (10), 1782-1791. doi: 10.1373/clinchem.2007.087650

Novel neutrophil-derived proteins in bronchoalveolar lavage fluid indicate an exaggerated inflammatory response in pediatric cystic fibrosis patients

2007

Journal Article

Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages

Schroder, K., Spille, M., Pilz, A., Lattin, J., Bode, K. A., Irvine, K. M., Burrows, A. D., Ravasi, T., Weighardt, H., Stacey, K. J., Decker, T., Hume, D. A., Dalpke, A. H. and Sweet, M. J. (2007). Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages. Journal of Immunology, 179 (6), 3495-3503. doi: 10.4049/jimmunol.179.6.3495

Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages

2007

Journal Article

Erratum: Genome-wide analysis of mammalian promoter architecture and evolution (Nature Genetics (2006) 38, (626-635))

Carninci, Piero, Sandelin, Albin, Lenhard, Boris, Katayama, Shintaro, Shimokawa, Kazuro, Ponjavic, Jasmina, Semple, Colin A. M., Taylor, Martin S., Engström, Pär G., Frith, Martin C., Forrest, Alistair R. R., Alkema, Wynand B., Tan, Sin Lam, Plessy, Charles, Kodzius, Rimantas, Ravasi, Timothy, Kasukawa, Takeya, Fukuda, Shiro, Kanamori-Katayama, Mutsumi, Kitazume, Yayoi, Kawaji, Hideya, Kai, Chikatoshi, Nakamura, Mari, Konno, Hideaki, Nakano, Kenji, Mottagui-Tabar, Salim, Arner, Peter, Chesi, Alessandra, Gustincich, Stefano ... Hayashizaki, Yoshihide (2007). Erratum: Genome-wide analysis of mammalian promoter architecture and evolution (Nature Genetics (2006) 38, (626-635)). Nature Genetics, 39 (9), 1174-1174. doi: 10.1038/ng0907-1174b

Erratum: Genome-wide analysis of mammalian promoter architecture and evolution (Nature Genetics (2006) 38, (626-635))

2007

Journal Article

G-protein-coupled receptor expression, function, and signaling in macrophages

Lattin, J., Zidar, D., Schroder, K., Kellie, S., Hume, D. and Sweet, M. (2007). G-protein-coupled receptor expression, function, and signaling in macrophages. Journal of Leukocyte Biology, 82 (1), 16-32. doi: 10.1189/jlb.0107051

G-protein-coupled receptor expression, function, and signaling in macrophages

2007

Journal Article

The role of schlafen in macrophages and inflammation

van Zuijlen, WJM, Cook, AD, Ovchinnikov, DA, Kellie, S and Hume, DA (2007). The role of schlafen in macrophages and inflammation. Inflammation Research, 56, S389-S389.

The role of schlafen in macrophages and inflammation

2007

Journal Article

Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation

Forwood, J., Thakur, A., Guncar, G., Marfori, M., Mouradov, D., Meng, W., Robinson, J., Huber, T., Kellie, S., Martin, J. L., Hume, D. and Kobe, B. (2007). Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of The National Academy of Sciences of The United States of America, 104 (25), 10382-10387. doi: 10.1073/pnas.0700974104

Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation

2007

Journal Article

Neutrophilic schizophrenia: Breaching the barrier between innate and adaptive immunity

Ferrante, Antonio, Hii, Charles and Hume, David (2007). Neutrophilic schizophrenia: Breaching the barrier between innate and adaptive immunity. Immunology and Cell Biology, 85 (4), 265-266. doi: 10.1038/sj.icb.7100036

Neutrophilic schizophrenia: Breaching the barrier between innate and adaptive immunity