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2002 Journal Article Generation of Diversity in the Innate Immune System: Macrophage Heterogeneity Arises From Gene-Autonomous Transcriptional Probability of Individual Inducible GenesRavasi, T., Wells, C., Forrest, A., Walsh, N., Underhill, D. M., Wainwright, B. J., Aderem, A., Grimmond, S. and Hume, D. A. (2002). Generation of Diversity in the Innate Immune System: Macrophage Heterogeneity Arises From Gene-Autonomous Transcriptional Probability of Individual Inducible Genes. Journal of Immunology, 168 (1), 44-50. doi: 10.4049/jimmunol.168.1.44 |
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2002 Journal Article Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cellsTagoh, H., Himes, R., Clarke, D., Leenen, P. J. M., Riggs, A. D., Hume, D. and Bonifer, C. (2002). Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells. Genes and Development, 16 (13), 1721-1737. doi: 10.1101/gad.222002 |
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2002 Journal Article The mononuclear phagocyte system revisitedHume, David A., Ross, Ian L., Himes, S. Roy, Sasmono, R. Tedjo, Wells, Christine A. and Ravasi, Timothy (2002). The mononuclear phagocyte system revisited. Journal of Leukocyte Biology, 72 (4), 621-627. doi: 10.1189/jlb.72.4.621 |
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2002 Journal Article The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoterMansky, K. C., Sulzbacher, S., Purdom, G., Nelsen, L., Hume, D. A., Rehli, M. and Ostrowski, M. C. (2002). The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. Journal of Leukocyte Biology, 71 (2), 304-310. doi: 10.1189/jlb.71.2.304 |
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2002 Journal Article Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolismWardrop, S. L., Wells, C., Ravasi, T., Hume, D. A. and Richardson, D. R. (2002). Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism. Journal of Leukocyte Biology, 71 (1), 99-106. doi: 10.1189/jlb.71.1.99 |
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2002 Journal Article Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophagesSweet, Matthew J., Campbell, Carol C., Sester, David P., Xu, Damo, McDonald, Rebecca C., Stacey, Katryn J., Hume, David A. and Liew, Foo Y. (2002). Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. Journal of Immunology, 168 (1), 392-399. doi: 10.4049/jimmunol.168.1.392 |
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2001 Journal Article A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expressionHimes, S. R., Tagoh, H., Goonetilleke, N., Sasmono, T., Oceandy, D., Clark, R., Bonifer, C. and Hume, D. A. (2001). A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression. Journal of Leukocyte Biology, 70 (5), 812-820. doi: 10.1189/jlb.70.5.812 |
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2001 Journal Article Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation stateHume, D. A., Underhill, D. M., Sweet, M. J., Ozinsky, A.O., Liew, F.Y. and Aderem, A. (2001). Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. BMC Immunology, 2 (11) 11, 1-12. doi: 10.1186/1471-2172-2-11 |
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2001 Journal Article G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung diseaseMcmorran, B., Palmer, J., Lunn, D., Oceandy, D., Costelloe, E. O., Thomas, G., Hume, D. A. and Wainwright, B. J. (2001). G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung disease. AJP-Lung Cellular and Molecular Physiology, 281 (3), 740-747. doi: 10.1152/ajplung.2001.281.3.L740 |
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2001 Journal Article Transcriptional regulation of c-fms gene expressionXie, Y., Chen, C. M. and Hume, D. A. (2001). Transcriptional regulation of c-fms gene expression. Cell Biochemistry And Biophysics, 34 (1), 1-16. doi: 10.1385/CBB:34:1:001 |
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2001 Journal Article Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiationLuchin, A., Suchting, S., Merson, T., Rosol, T. J., Hume, D. A., Cassady, A. I. and Ostrowski, M. C. (2001). Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation. Journal of Biological Chemistry, 276 (39), 36703-36710. doi: 10.1074/jbc.M106418200 |
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2001 Journal Article Structural genomics: Protein structures for the masses?Walsh, C. R., Hume, D. A., Kobe, B. and Martin, J. L. (2001). Structural genomics: Protein structures for the masses?. Australian Biochemist, 32 (2), 13-16. |
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2000 Journal Article Heat shock enhances transcriptional activation of the murine-inducible nitric oxide synthase geneGoldring, C. E., Reveneau, S., Chantome, A., Pance, A., Fleury, C., Hume, D. A., Sester, D., Mignotte, B. and Jeannin, J. F. (2000). Heat shock enhances transcriptional activation of the murine-inducible nitric oxide synthase gene. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14 (15), 2393-2395. doi: 10.1096/fj.98-0509fje |
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2000 Journal Article Structure, function and regulation of tartrate-resistant acid phosphataseOddie, G. W., Schenk, G., Angel, N. Z., Walsh, N., Guddat, L. W., deJersey, J., Cassady, A. I., Hamilton, S. E. and Hume, D. A. (2000). Structure, function and regulation of tartrate-resistant acid phosphatase. Bone, 27 (5), 575-584. doi: 10.1016/S8756-3282(00)00368-9 |
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2000 Journal Article G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophagesThomas, Gordon R., Costelloe, E. A., Lunn, D. P., Stacey, K. J., Passey, R., McGlinn, E. C., McMorran, B. J., Ahadizadeh, A., Geczy, C. L., Wainwright, B. J. and Hume, D. A. (2000). G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophages. The Journal of Immunology, 164 (7), 3870-3877. doi: 10.4049/jimmunol.164.7.3870 |
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2000 Journal Article Regulation of rat 25-hyrdoxyvitamin D3 24-hydroxylase (CYP024) gene expression: Evidence for cooperation of ras-activated Ets transcription factors with vitamin D receptor in 1,25-hihyroxyvitamin D3 mediated inductionDwidedi, P. P., Omdahl, J. L., Kola, I., Hume, D. A. and Kay, B. K. (2000). Regulation of rat 25-hyrdoxyvitamin D3 24-hydroxylase (CYP024) gene expression: Evidence for cooperation of ras-activated Ets transcription factors with vitamin D receptor in 1,25-hihyroxyvitamin D3 mediated induction. Journal of Biological Chemistry, 275 (1), 47-55. doi: 10.1074/jbc.275.1.47 |
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2000 Journal Article Phosphorothioate backbone modification modulates macrophage activation by CpG DNA1Sester, D. P., Naik, S., Beasley, S. J., Hume, D. A. and Stacey, K. J. (2000). Phosphorothioate backbone modification modulates macrophage activation by CpG DNA1. The Journal of Immunology, 165 (8), 4165-4173. doi: 10.4049/jimmunol.165.8.4165 |
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2000 Journal Article Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expressionHume, David A. (2000). Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression. Blood, 96 (7), 2323-2328. doi: 10.1182/blood.v96.7.2323.h8002323_2323_2328 |
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2000 Journal Article The microphthalmia transcription factor regulates expression of the tartrate resistant acid phosphatase gene during terminal differentiation of osteoclastsLuchin, A., Purdom, G., Murphy, K. M., Clark, M., Angel, N., Cassady, A. I., Hume, D. A. and Ostrowski, M. (2000). The microphthalmia transcription factor regulates expression of the tartrate resistant acid phosphatase gene during terminal differentiation of osteoclasts. Journal of Bone and Mineral Research, 15 (3), 451-460. doi: 10.1359/jbmr.2000.15.3.451 |
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2000 Journal Article Regulation of the urokinase plasminogen activator gene in macrophages by macrophage colony-stimulating factor (CSF-1) is dependent upon the level of cell surface receptorFowles, L. F., Stacey, K. J., Marks, D., Hamilton, J. A. and Hume, D. A. (2000). Regulation of the urokinase plasminogen activator gene in macrophages by macrophage colony-stimulating factor (CSF-1) is dependent upon the level of cell surface receptor. Biochemical Journal, 347 (1), 313-320. doi: 10.1042/0264-6021:3470313 |
