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2018 Journal Article An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysisRyan, Timothy M., Trewhella, Jill, Murphy, James M., Keown, Jeremy R., Casey, Lachlan, Pearce, F. Grant, Goldstone, David C., Chen, Kelan, Luo, Zhenyao, Kobe, Bostjan, McDevitt, Christopher A., Watkin, Serena A., Hawley, Adrian M., Mudie, Stephen T., Boban, Vesna Samardzic and Kirby, Nigel (2018). An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis. Journal of Applied Crystallography, 51 (1), 97-111. doi: 10.1107/S1600576717017101 |
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2018 Journal Article Structural and functional characterization of a cross-reactive dengue virus neutralizing antibody that recognizes a cryptic epitopeLi, Jie, Watterson, Daniel, Chang, Chiung-Wen, Che, Xiao-Yan, Li, Xiao-Quan, Ericsson, Daniel J., Qiu, Li-Wen, Cai, Jian-Piao, Chen, Jing, Fry, Scott R., Cheung, Stacey T. M., Cooper, Matthew A., Young, Paul R. and Kobe, Bostjan (2018). Structural and functional characterization of a cross-reactive dengue virus neutralizing antibody that recognizes a cryptic epitope. Structure, 26 (1), 51-59. doi: 10.1016/j.str.2017.11.017 |
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2018 Other Outputs Structural and Functional Characterization of a Cross‐Reactive Dengue Virus Neutralizing Antibody That Recognizes a Cryptic EpitopeLi, Jie, Watterson, Daniel, Chang, Chiung-Wen, Che, Xiao-Yan, Li, Xiao-Quan, Ericsson, Daniel J., Qiu, Li-Wen, Cai, Jian-Piao, Chen, Jing, Fry, Scott R., Cooper, Matthew, Young, Paul and Kobe, Bostjan (2018). Structural and Functional Characterization of a Cross‐Reactive Dengue Virus Neutralizing Antibody That Recognizes a Cryptic Epitope. doi: 10.2139/ssrn.3155754 |
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2018 Conference Publication Crystallographic and calorimetric studies with nuclear transport of DNA repair proteinsde Mattos Fontes, Marcos Roberto, de Barros, Andrea, Bernardes, Natalia, Takeda, Agnes, Dreyer, Thiago, Bertolini, Maria Celia and Kobe, Bostjan (2018). Crystallographic and calorimetric studies with nuclear transport of DNA repair proteins. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1107/S2053273318092434 |
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2017 Journal Article DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathwayde Barros, Andrea C, Takeda, Agnes A S, Dreyer, Thiago R, Velazquez-Campoy, Adrian, Kobe, Boštjan and Fontes, Marcos R M (2017). DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway. Biochimie, 146, 87-96. doi: 10.1016/j.biochi.2017.11.013 |
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2017 Journal Article Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein PZhang, Xiaoxiao, Farah, Nadya, Rolston, Laura, Ericsson, Daniel J., Catanzariti, Ann-Maree, Bernoux, Maud, Ve, Thomas, Bendak, Katerina, Chen, Chunhong, Mackay, Joel P., Lawrence, Gregory J., Hardham, Adrienne, Ellis, Jeffrey G., Williams, Simon J., Dodds, Peter N., Jones, David A. and Kobe, Bostjan (2017). Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P. Molecular Plant Pathology, 19 (5), 1196-1209. doi: 10.1111/mpp.12597 |
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2017 Journal Article Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signalingHughes, Mark M., Lavrencic, Peter, Coll, Rebecca C., Ve, Thomas, Ryan, Dylan G., Williams, Niamh C., Menon, Deepthi, Mansell, Ashley, Board, Philip G., Mobli, Mehdi, Kobe, Bostjan and O'Neill, Luke A. J. (2017). Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. Proceedings of the National Academy of Sciences, 114 (32), E6480-E6489. doi: 10.1073/pnas.1701868114 |
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2017 Journal Article Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signalingVe, Thomas, Vajjhala, Parimala, Hedger, Andrew, Croll, Tristan, DiMaio, Frank, Horsefield, Shane, Yu, Xiong, Lavrencic, Peter, Hassan, Zahid, Morgan, Garry P., Mansell, Ashley, Mobli, Mehdi, O'Carroll, Ailis, Chauvin, Brieuc, Gambin, Yann, Sierecki, Emma, Landsberg, Michael J., Stacey, Katryn, Egelman, Edward H. and Kobe, Bostjan (2017). Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling. Nature Structural and Molecular Biology, 24 (9), 743-751. doi: 10.1038/nsmb.3444 |
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2017 Journal Article Emerging insights into the functions of pathogenesis-related protein 1Breen, Susan, Williams, Simon J., Outram, Megan, Kobe, Bostjan and Solomon, Peter S. (2017). Emerging insights into the functions of pathogenesis-related protein 1. Trends in Plant Science, 22 (10), 871-879. doi: 10.1016/j.tplants.2017.06.013 |
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2017 Journal Article Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug designChitty, Jessica L., Blake, Kirsten L., Blundell, Ross D., Koh, Y. Q. Andre E., Thompson, Merinda, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kappler, Ulrike, Williams, Simon J., Kobe, Bostjan and Fraser, James A. (2017). Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design. Journal of Biological Chemistry, 292 (28), 11829-11839. doi: 10.1074/jbc.M117.787994 |
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2017 Journal Article The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathwaysVajjhala, Parimala R., Ve, Thomas, Bentham, Adam, Stacey, Katryn J. and Kobe, Bostjan (2017). The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways. Molecular Immunology, 86, 23-37. doi: 10.1016/j.molimm.2017.02.012 |
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2017 Journal Article Towards the structure of the TIR-domain signalosomeNimma, Surekha, Ve, Thomas, Williams, Simon J. and Kobe, Bostjan (2017). Towards the structure of the TIR-domain signalosome. Current Opinion In Structural Biology, 43, 122-130. doi: 10.1016/j.sbi.2016.12.014 |
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2017 Conference Publication Prion ‐ like protein polymerisation underlies signal transduction in innate immunity: The emergence of a universal mechanism ?O'Carroll, Ailis, Ve, Thomas, Moustaqil, Mehdi, Giles, Nichole, Bhumkar, Akshay, Hunter, Dominic, Kobe, Bostjan, Sierecki, Emma and Gambin, Yann (2017). Prion ‐ like protein polymerisation underlies signal transduction in innate immunity: The emergence of a universal mechanism ?. Experimental Biology 2017 Meeting, Chicago, IL United States, 22-26 April 2017. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.31.1_supplement.937.1 |
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2017 Journal Article GMP synthase is required for virulence factor production and infection by cryptococcus neoformansChitty, Jessica L., Tatzenko, Tayla L. , Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2017). GMP synthase is required for virulence factor production and infection by cryptococcus neoformans. Journal of Biological Chemistry, 292 (7), 3049-3059. doi: 10.1074/jbc.M116.767533 |
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2017 Journal Article A non-uniform sampling approach enables studies of dilute and unstable proteinsMiljenović, Tomas, Jia, Xinying, Lavrencic, Peter, Kobe, Bostjan and Mobli, Mehdi (2017). A non-uniform sampling approach enables studies of dilute and unstable proteins. Journal of Biomolecular NMR, 68 (2), 1-9. doi: 10.1007/s10858-017-0091-z |
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2017 Journal Article PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylationPatrick, Ralph, Kobe, Bostjan, Lê Cao, Kim-Anh and Bodén, Mikael (2017). PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation. Bioinformatics, 33 (12), 1773-1781. doi: 10.1093/bioinformatics/btx072 |
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2017 Journal Article Multiple functional self-association interfaces in plant TIR domainsZhang, Xiaoxiao, Bernoux, Maud, Bentham, Adam R., Newman, Toby E., Ve, Thomas, Casey, Lachlan W., Raaymakers, Tom M., Hu, Jian, Croll, Tristan I., Schreiber, Karl J., Staskawicz, Brian J., Anderson, Peter A., Sohn, Kee Hoon, Williams, Simon J., Dodds, Peter N. and Kobe, Bostjan (2017). Multiple functional self-association interfaces in plant TIR domains. Proceedings of the National Academy of Sciences, 114 (10), E2046-E2052. doi: 10.1073/pnas.1621248114 |
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2017 Journal Article Blood group antigen recognition via the group A Streptococcal M protein mediates host colonizationDe Oliveira, David M. P., Hartley-Tassell, Lauren, Everest-Dass, Arun, Day, Christopher J., Dabbs, Rebecca A., Ve, Thomas, Kobe, Bostjan, Nizet, Victor, Packer, Nicolle H., Walker, Mark J., Jennings, Michael P. and Sanderson-Smith, Martina L. (2017). Blood group antigen recognition via the group A Streptococcal M protein mediates host colonization. MBio, 8 (1) e02237-16, e02237-16. doi: 10.1128/mBio.02237-16 |
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2017 Conference Publication Structural characterization of pseudo-dihyroorotase domain in yeast URA2Jeon, Yujung, Ross, Ian, Landsberg, Michael, Hankamer, Ben and Kobe, Bostjan (2017). Structural characterization of pseudo-dihyroorotase domain in yeast URA2. XXIV IUCr Congress, Hyderabad, India, 21-28 August 2017. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1107/s2053273317090325 |
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2017 Conference Publication Structural characterisation of SARM in axon degeneration and cell deathHorsefield, Shane Michael, Ve, Thomas, Zhang, Xiaoxiao, Casey, Lachlan and Kobe, Bostjan (2017). Structural characterisation of SARM in axon degeneration and cell death. IUCr Congress, Hyderabad, India, 21-28 August 2017. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1107/S205327331708740X |
