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2013

Journal Article

Identifying key amino acid residues that affect alpha-conotoxin AuIB inhibition of alpha3beta4 nicotinic acetylcholine receptors

Grishin, Anton A., Cuny, Hartmut, Hung, Andrew, Clark, Richard J., Brust, Andreas, Akondi, Kalyana, Alewood, Paul F., Craik, David J. and Adams, David J. (2013). Identifying key amino acid residues that affect alpha-conotoxin AuIB inhibition of alpha3beta4 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 288 (48), 34428-34442. doi: 10.1074/jbc.M113.512582

Identifying key amino acid residues that affect alpha-conotoxin AuIB inhibition of alpha3beta4 nicotinic acetylcholine receptors

2013

Journal Article

Novel inhibitor cystine knot peptides from momordica charantia

He, Wen-Jun, Chan, Lai Yue, Clark, Richard J., Tang, Jun, Zeng, Guang-Zhi, Franco, Octavio L., Cantacessi, Cinzia, Craik, David J., Daly, Norelle L. and Tan, Ning-Hua (2013). Novel inhibitor cystine knot peptides from momordica charantia. PLoS ONE, 8 (10) e75334, e75334.1-e75334.10. doi: 10.1371/journal.pone.0075334

Novel inhibitor cystine knot peptides from momordica charantia

2013

Journal Article

Design, synthesis and characterisation of cyclic analogues of the iron regulatory peptide hormone hepcidin

Clark, Richard J., Preza, Gloria C., Tan, Chia Chia, van Dijk, Johannes W. A., Fung, Eileen, Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2013). Design, synthesis and characterisation of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers: Peptide Science, 100 (5), 519-526. doi: 10.1002/bip.22350

Design, synthesis and characterisation of cyclic analogues of the iron regulatory peptide hormone hepcidin

2013

Journal Article

The zebrafish reference genome sequence and its relationship to the human genome

Howe, Kerstin, Clark, Matthew D., Torroja, Carlos F., Torrance, James, Berthelot, Camille, Muffato, Matthieu, Collins, John E., Humphray, Sean, McLaren, Karen, Matthews, Lucy, McLaren, Stuart, Sealy, Ian, Caccamo, Mario, Churcher, Carol, Scott, Carol, Barrett, Jeffrey C., Koch, Romke, Rauch, Gerd-Joerg, White, Simon, Chow, William, Kilian, Britt, Quintais, Leonor T., Guerra-Assuncao, Jose A., Zhou, Yi, Gu, Yong, Yen, Jennifer, Vogel, Jan-Hinnerk, Eyre, Tina, Redmond, Seth ... Stemple, Derek L. (2013). The zebrafish reference genome sequence and its relationship to the human genome. Nature, 496 (7446), 498-503. doi: 10.1038/nature12111

The zebrafish reference genome sequence and its relationship to the human genome

2013

Journal Article

The genomes of four tapeworm species reveal adaptations to parasitism

Tsai, Isheng J., Zarowiecki, Magdalena, Holroyd, Nancy, Garciarrubio, Alejandro, Sanchez-Flores, Alejandro, Brooks, Karen L., Tracey, Alan, Bobes, Raul J., Fragoso, Gladis, Sciutto, Edda, Aslett, Martin, Beasley, Helen, Bennett, Hayley M., Cai, Jianping, Camicia, Federico, Clark, Richard, Cucher, Marcela, De Silva, Nishadi, Day, Tim A., Deplazes, Peter, Estrada, Karel, Fernandez, Cecilia, Holland, Peter W. H., Hou, Junling, Hu, Songnian, Huckvale, Thomas, Hung, Stacy S., Kamenetzky, Laura, Keane, Jacqueline A. ... Berriman, Matthew (2013). The genomes of four tapeworm species reveal adaptations to parasitism. Nature, 496 (7443), 57-63. doi: 10.1038/nature12031

The genomes of four tapeworm species reveal adaptations to parasitism

2013

Conference Publication

Development of analgesic alpha-conotoxins for treatment of chronic pain

Adams, D. J., Berecki, G., Clark, R. and Craik, D. J. (2013). Development of analgesic alpha-conotoxins for treatment of chronic pain. 4th Meeting of the Australia Chinese Association for Biomedical Sciences Inc (ACABS), Hangzhou Peoples R China, 10-13 October 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/1440-1681.12170

Development of analgesic alpha-conotoxins for treatment of chronic pain

2013

Conference Publication

alpha-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency

Kompella, Shiva N., Hung, Andrew, Clark, Richard J. and Adams, David J. (2013). alpha-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency. 57th Annual Meeting of the Biophysical Society, Philadelphia Pa, 02-06 February 2013. Maryland Heights, MO United States: Cell Press. doi: 10.1016/j.bpj.2012.11.3505

alpha-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency

2012

Journal Article

Cyclization of conotoxins to improve their biopharmaceutical properties

Clark, Richard J., Akcan, Muharrem, Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2012). Cyclization of conotoxins to improve their biopharmaceutical properties. Toxicon, 59 (4), 446-455. doi: 10.1016/j.toxicon.2010.12.003

Cyclization of conotoxins to improve their biopharmaceutical properties

2012

Journal Article

Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2012). Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38). Current Pharmaceutical Design, 18 (8). doi: 10.2174/138161212799315858

Corrigendum: Engineering of Conotoxins for the Treatment of Pain (Current Pharmaceutical Design, (2011), 17, 38)

2012

Journal Article

Engineering cyclic peptide toxins

Clark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3

Engineering cyclic peptide toxins

2012

Conference Publication

Novel single-chain ligands for the relaxin-3 receptor RXFP3

Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

Novel single-chain ligands for the relaxin-3 receptor RXFP3

2012

Conference Publication

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

Clark, R. J., Tan, C., Preza, G. C., Nemeth, E., Ganz, T. and Craik, D. J. (2012). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 2-7 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448

Understanding the structure/activity relationships of the iron regulatory peptide hepcidin

2012

Conference Publication

Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds

Chan, L. A., Gunasekera, S., Henriques, S. T., Worth, N. F., Le, S., Clark, R. J., Campbell, J. H., Craik, D. J. and Daly, N. L. (2012). Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds. 32nd European Peptide Symposium, Athens, Greece, 2-7 September 2012. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.2448

Engineering pro-angiogenic peptides using stable disulfide-rich scaffolds

2011

Journal Article

Engineering of conotoxins for the treatment of pain

Carstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401

Engineering of conotoxins for the treatment of pain

2011

Journal Article

Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds

Chan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141

Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds

2011

Journal Article

Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor

Halai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r

Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor

2011

Journal Article

Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry

Joron, Mathieu, Frezal, Lise, Jones, Robert T., Chamberlain, Nicola L., Lee, Siu F., Haag, Christoph R., Whibley, Annabel, Becuwe, Michel, Baxter, Simon W., Ferguson, Laura, Wilkinson, Paul A., Salazar, Camilo, Davidson, Claire, Clark, Richard, Quail, Michael A., Beasley, Helen, Glithero, Rebecca, Lloyd, Christine, Sims, Sarah, Jones, Matthew C., Rogers, Jane, Jiggins, Chris D. and Ffrench-Constant, Richard H. (2011). Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry. Nature, 477 (7363), 203-U102. doi: 10.1038/nature10341

Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry

2011

Journal Article

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

Wang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

2011

Journal Article

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

2011

Journal Article

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

Daly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels