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2012 Journal Article Engineering cyclic peptide toxinsClark, Richard J. and Craik, David J. (2012). Engineering cyclic peptide toxins. Methods in Enzymology, 503, 57-74. doi: 10.1016/B978-0-12-396962-0.00003-3 |
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2012 Conference Publication Novel single-chain ligands for the relaxin-3 receptor RXFP3Rosengren, K. J., Haugaard-Kedstroem, L. M., Jones, M., Clark, R. J. and Bathgate, R. A. D. (2012). Novel single-chain ligands for the relaxin-3 receptor RXFP3. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2448 |
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2011 Journal Article Engineering of conotoxins for the treatment of painCarstens, Bodil B., Clark, Richard J., Daly, Norelle L., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2011). Engineering of conotoxins for the treatment of pain. Current Pharmaceutical Design, 17 (38), 4242-4253. doi: 10.2174/138161211798999401 |
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2011 Journal Article Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffoldsChan, Lai Y., Gunasekera, Sunithi, Henriques, Sonia T., Worth, Natalie F., Le, Sarah-Jane, Clark, Richard J., Campbell, Julie H., Craik, David J. and Daly, Norelle L. (2011). Engineering pro-angiogenic peptides using stable disulfide-rich cyclic scaffolds. Blood, 118 (25), 6709-6717. doi: 10.1182/blood-2011-06-359141 |
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2011 Journal Article Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptorHalai, Reena, Callaghan, Brid, Daly, Norelle L., Clark, Richard J., Adams, David J. and Craik, David J. (2011). Effects of cyclization on stability, structure, and activity of alpha-conotoxin RgIA at the alpha 9 alpha 10 nicotinic acetylcholine receptor and GABA(B) receptor. Journal of Medicinal Chemistry, 54 (19), 6984-6992. doi: 10.1021/jm201060r |
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2011 Journal Article The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutantWang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153 |
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2011 Journal Article Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D. and Rosengren, K. Johan (2011). Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society, 133 (13), 4965-4974. doi: 10.1021/ja110567j |
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2011 Journal Article Understanding the structure/activity relationships of the iron regulatory peptide hepcidinClark, Richard J., Tan, Chia Chia, Preza, Gloria C., Nemeth, Elizabeta, Ganz, Tomas and Craik, David J. (2011). Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry and Biology, 18 (3), 336-343. doi: 10.1016/j.chembiol.2010.12.009 |
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2011 Journal Article Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channelsDaly, Norelle L., Callaghan, Brid, Clark, Richard J., Nevin, Simon T., Adams, David J. and Craik, David J. (2011). Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. Journal of Biological Chemistry, 286 (12), 10233-10237. doi: 10.1074/jbc.M110.196170 |
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2011 Journal Article Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapyAkcan, M, Stroud, MR, Hansen, SJ, Clark, RJ, Daly, NL, Craik, DJ and Olson, JM (2011). Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry, 54 (3), 782-787. doi: 10.1021/jm101018r |
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2011 Conference Publication Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptorAdams, D. J., Grishin, A. A., Hung, A., Clark, R. J., Akondi, K., Alewood, P. F. and Craik, D. J. (2011). Scanning mutagenesis of alpha-conotoxin AuIB reveals a critical residue for activity at the alpha-3-beta-4 nicotinic acetylcholine receptor. nAChR2011: Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science, Washington, DC, U.S.A., 9-11 November 2011. Philadelphia, PA, U.S.A.: Elsevier. doi: 10.1016/j.bcp.2011.07.017 |
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2011 Journal Article Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of CyclotidesAboye, Teshome Leta, Clark, Richard J., Burman, Robert, Roig, Marta Bajona, Craik, David J. and Goransson, Ulf (2011). Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides. Antioxidants & Redox Signaling, 14 (1), 77-86. doi: 10.1089/ars.2010.3112 |
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2011 Journal Article Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclizationLovelace, Erica S., Gunasekera, Sunithi, Alvarmo, Charlotta, Clark, Richard J., Nevin, Simon T., Grishin, Anton A., Adams, David J., Craik, David J. and Daly, Norelle L. (2011). Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization. Antioxidants and Redox Signaling, 14 (1), 87-95. doi: 10.1089/ars.2009.3068 |
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2010 Journal Article Structural and functional analysis of human liver-expressed antimicrobial peptide 2Henriques, Sonia Troeira, Tan, Chia Chia, Craik, David J. and Clark, Richard J. (2010). Structural and functional analysis of human liver-expressed antimicrobial peptide 2. ChemBioChem, 11 (15), 2148-2157. doi: 10.1002/cbic.201000400 |
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2010 Journal Article Isolation, sequencing, and structure - Activity relationships of cyclotidesIreland, David C., Clark, Richard J., Daly, Norelle L. and Craik, David J. (2010). Isolation, sequencing, and structure - Activity relationships of cyclotides. Journal of Natural Products, 73 (9), 1610-1622. doi: 10.1021/np1000413 |
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2010 Journal Article ChemInform Abstract: Native Chemical Ligation Applied to the Synthesis and Bioengineering of Circular Peptides and ProteinsClark, Richard J. and Craik, David J. (2010). ChemInform Abstract: Native Chemical Ligation Applied to the Synthesis and Bioengineering of Circular Peptides and Proteins. ChemInform, 41 (41). doi: 10.1002/chin.201041266 |
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2010 Journal Article The engineering of an orally active conotoxin for the treatment of neuropathic painClark, Richard J., Jensen, Jonas, Nevin, Simon T., Callaghan, Brid P., Adams, David J. and Craik, David J. (2010). The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angewandte Chemie (International Edition), 49 (37), 6545-6548. doi: 10.1002/anie.201000620 |
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2010 Journal Article Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activityHuang, Yen-Hua (黃彥華), Colgrave, Michelle L., Clark, Richard J., Kotze, Andrew C. and Craik, David J. (2010). Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity. Journal of Biological Chemistry, 285 (14), 10797-10805. doi: 10.1074/jbc.M109.089854 |
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2010 Conference Publication Evaluation of toxicity and antitumor activity of cycloviolacin O2 in miceBurman, Robert, Svedlund, Erika, Felth, Jenny, Hassan, Saadia, Hermann, Anders, Clark, Richard James, Craik, David J., Bohlin, Lars, Claeson, Per, Goransson, Ulf and Gullbo, Joachim (2010). Evaluation of toxicity and antitumor activity of cycloviolacin O2 in mice. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October, 2009. Hoboken, NJ, U.S.A: Wiley Interscience. doi: 10.1002/bip.21408 |
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2010 Conference Publication Sunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogsColgrave, Michelle, Korsinczky, Michael Laszlo Jonas, Clark, Richard James, Foley, Fiona and Craik, David J. (2010). Sunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogs. 1st International Conference on Circular Proteins, Heron Island, Qld, Australia, 18-21 October 2009. Hoboken, N.J., U.S.: John Wiley & Sons. doi: 10.1002/bip.21415 |
