|
2006 Journal Article The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200 |
|
2006 Journal Article Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motifDaly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371 |
|
2006 Journal Article Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug designClark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691 |
|
2006 Journal Article The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffoldDaly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200 |
|
2005 Book Chapter Structure-based drug design and NMR-based screeningCraik, D. J. and Clark, R. J. (2005). Structure-based drug design and NMR-based screening. Encyclopdeia of Molecular Cell Biology and Molecular Medicine. (pp. 517-605) edited by Robert A Meyers. Germany: Wiley-VCH. |
|
2005 Journal Article Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MIIClark, R. J., Fischer, H., Dempster, L., Daly, N. L., Rosengren, K. J., Nevin, S. T., Meunier, F. A., Adams, D. J. and Craik, D. J. (2005). Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII. Proceedings of The National Academy of Sciences of The United States of America, 102 (39), 13767-13772. doi: 10.1073/pnas.0504613102 |
|
2005 Conference Publication A novel threaded ring structure for the antimicrobial peptide microcin J25Rosengren, KJ, Jen, FEC, Clark, RJ, Goransson, U, Daly, NL and Craik, DJ (2005). A novel threaded ring structure for the antimicrobial peptide microcin J25. Peptides 2004: 3rd International Peptide Symposium / 28th European Peptide Symposium, Prague, Czech Republic, 5 - 10 September 2004. Geneva, Switzerland: Kenes International. |
|
2005 Journal Article Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1Korsinczky, M. L. J., Clark, R. J. and Craik, D. J. (2005). Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1. Biochemistry, 44 (4), 1145-1153. doi: 10.1021/bi048297r |
|
2004 Conference Publication Cyclotides: Novel Peptidic Pesticides for Plant ProtectionPlan, MR, Goransson, U, Rosengren, KJ, Clark, RJ, Daly, NL, Evert, P, Chen, C, Cagauan, AG and Craik, DJ (2004). Cyclotides: Novel Peptidic Pesticides for Plant Protection. CHICHESTER: JOHN WILEY & SONS LTD. |
|
2004 Journal Article Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteinsDutton, J. L., Renda, R. F., Waine, C., Clark, R. J., Daly, N. L., Jennings, C. V., Anderson, M. A. and Craik, D. J. (2004). Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. Journal of Biological Chemistry, 279 (45), 46858-46867. doi: 10.1074/jbc.M407421200 |
|
2004 Conference Publication A novel threaded ring structure for the antimicrobial peptide microcin J25Craik, D. J., Rosengren, K. J., Clark, R. J., Daly, N. L. and Goransson, U. (2004). A novel threaded ring structure for the antimicrobial peptide microcin J25. 3rd International and 28th European Peptide Symposium, Prague, Czech Republic, 5–10 September 2004. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.617 |
|
2004 Conference Publication Design, Synthesis and Structural Studies of Cyclic Alpha-ConotoxinsClark, RJ, Dempster, L, Daly, NL, Rosengren, KJ and Craik, DJ (2004). Design, Synthesis and Structural Studies of Cyclic Alpha-Conotoxins. CHICHESTER: JOHN WILEY & SONS LTD. |
|
2003 Conference Publication Probing nucleotide dissociation from myosin in vitro using microgram quantities of myosinClark, Richard J., Nyitrai, Miklós, Webb, Martin R. and Geeves, Michael A. (2003). Probing nucleotide dissociation from myosin in vitro using microgram quantities of myosin. |
|
2003 Journal Article Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotidesDaly, N. L., Clark, R. J. and Craik, D. J. (2003). Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides. The Journal of Biological Chemistry, 278 (8), 6314-6322. doi: 10.1074/jbc.M210492200 |
|
2003 Book Chapter NMR and Drug DiscoveryCraik, D. J. and Clark, R. J. (2003). NMR and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery, Vol 1, Drug Discovery. (pp. 507-582) edited by Donald J Abraham. USA: John Wiley & Sons. doi: 10.1002/0471266949.bmc011 |
|
2003 Journal Article Structure-function studies of the plant cyclotides: The role of a circular protein backboneCraik, David J., Barry, Daniel G., Clark, Richard J., Daly, Norelle L. and Sando, Lillian (2003). Structure-function studies of the plant cyclotides: The role of a circular protein backbone. Toxin Reviews, 22 (4), 555-576. doi: 10.1081/TXR-120026914 |
|
2003 Journal Article Structure-function studies of the plant cyclotides: the role of a circular protein backboneCraik, David J., Barry, Daniel G., Clark, Richard J., Daly, Norelle L. and Sando, Lillian (2003). Structure-function studies of the plant cyclotides: the role of a circular protein backbone. Journal of Toxicology: Toxin Reviews, 22 (4), 555-576. doi: 10.1081/TXR-120026914 |
|
2003 Journal Article Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activityBarry, D. G., Daly, N. L., Clark, R. J., Sando, L. and Craik, D. J. (2003). Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity. Biochemistry, 42 (22), 6688-6695. doi: 10.1021/bi027323n |
|
2003 Journal Article Diversity in the disulfide folding pathways of cystine knot peptidesDaly, N. L., Clark, R. J., Goransson, U. and Craik, D. J. (2003). Diversity in the disulfide folding pathways of cystine knot peptides. Letters in Peptide Science, 10 (5-6), 523-531. doi: 10.1007/BF02442584 |
|
2003 Journal Article Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backboneRosengren, K. J., Clark, R. J., Daly, N. L., Goransson, U., Jones, A. and Craik, D. J. (2003). Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. Journal of the American Chemical Society, 125 (41), 12464-12474. doi: 10.1021/JA0367703 |
