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2008 Conference Publication Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090 |
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2008 Conference Publication Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, 3-8 August 2008. Germany: Georg Thieme Verlag. |
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2007 Journal Article Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?Nevin, Simon T., Clark, Richard J., Klimis, H., Christie, M. J., Craik, David J. and Adams, David J. (2007). Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?. Molecular Pharmacology, 72 (6), 1406-1410. doi: 10.1124/mol.107.040568 |
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2007 Journal Article Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamicsJin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28 |
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2007 Journal Article Potential therapeutic applications of the cyclotides and related cystine knot mini-proteinsCraik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595 |
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2007 Journal Article The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitroGunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540. |
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2007 Journal Article The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptidesPlan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097 |
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2007 Conference Publication Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptidesGruber, G. W., Cemazar, M., Clark, R., Horibe, T., Renda, R., Anderson, M. A. and Craik, D. J. (2007). Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides. 20th American-Peptide-Society Symposium, Montréal, Canada, 26-30 Jun 2007. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.20783 |
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2007 Journal Article A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteinsGruber, C. W, Cemazar, M., Clark, R. .J, Horibe, T, Renda, R. F., Anderson, M. A. and Craik, D. J. (2007). A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins. Journal of Biological Chemistry, 282 (28), 20435-20446. doi: 10.1074/jbc.M700018200 |
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2006 Journal Article The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200 |
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2006 Journal Article The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffoldDaly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200 |
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2006 Journal Article Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motifDaly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371 |
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2006 Journal Article Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug designClark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691 |
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2005 Journal Article Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1Korsinczky, M. L. J., Clark, R. J. and Craik, D. J. (2005). Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1. Biochemistry, 44 (4), 1145-1153. doi: 10.1021/bi048297r |
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2005 Book Chapter Structure-based drug design and NMR-based screeningCraik, D. J. and Clark, R. J. (2005). Structure-based drug design and NMR-based screening. Encyclopdeia of Molecular Cell Biology and Molecular Medicine. (pp. 517-605) edited by Robert A Meyers. Germany: Wiley-VCH. |
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2005 Journal Article Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MIIClark, R. J., Fischer, H., Dempster, L., Daly, N. L., Rosengren, K. J., Nevin, S. T., Meunier, F. A., Adams, D. J. and Craik, D. J. (2005). Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the alpha-conotoxin MII. Proceedings of The National Academy of Sciences of The United States of America, 102 (39), 13767-13772. doi: 10.1073/pnas.0504613102 |
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2005 Conference Publication A novel threaded ring structure for the antimicrobial peptide microcin J25Rosengren, KJ, Jen, FEC, Clark, RJ, Goransson, U, Daly, NL and Craik, DJ (2005). A novel threaded ring structure for the antimicrobial peptide microcin J25. Peptides 2004: 3rd International Peptide Symposium / 28th European Peptide Symposium, Prague, Czech Republic, 5 - 10 September 2004. Geneva, Switzerland: Kenes International. |
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2004 Conference Publication Design, Synthesis and Structural Studies of Cyclic Alpha-ConotoxinsClark, RJ, Dempster, L, Daly, NL, Rosengren, KJ and Craik, DJ (2004). Design, Synthesis and Structural Studies of Cyclic Alpha-Conotoxins. CHICHESTER: JOHN WILEY & SONS LTD. |
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2004 Conference Publication Cyclotides: Novel Peptidic Pesticides for Plant ProtectionPlan, MR, Goransson, U, Rosengren, KJ, Clark, RJ, Daly, NL, Evert, P, Chen, C, Cagauan, AG and Craik, DJ (2004). Cyclotides: Novel Peptidic Pesticides for Plant Protection. CHICHESTER: JOHN WILEY & SONS LTD. |
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2004 Journal Article Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteinsDutton, J. L., Renda, R. F., Waine, C., Clark, R. J., Daly, N. L., Jennings, C. V., Anderson, M. A. and Craik, D. J. (2004). Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. Journal of Biological Chemistry, 279 (45), 46858-46867. doi: 10.1074/jbc.M407421200 |
