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2008 Journal Article The three-dimensional structure of the analgesic alpha-conotoxin, RgIAClark, Richard J., Daly, Norelle L., Halai, Reena, Nevin, Simon T., Adams, David J. and Craik, David J. (2008). The three-dimensional structure of the analgesic alpha-conotoxin, RgIA. FEBS Letters, 582 (5), 597-602. doi: 10.1016/j.febslet.2008.01.027 |
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2008 Journal Article The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicityHerrman, Anders, Burman, Robert, Mylne, Joshua S., Karlsson, Gustav, Gullbo, Joachim, Craik, David J., Clark, Richard J. and Goransson, Ulf (2008). The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity. Phytochemistry, 69 (4), 939-952. doi: 10.1016/j.phytochem.2007.10.023 |
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2008 Conference Publication Understanding the structure/activity relationships of hepcidinClark, Richard, Tan, Chia Chia, Nemeth, Elizabeta, Ganz, Thomas and Craik, David (2008). Understanding the structure/activity relationships of hepcidin. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090 |
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2008 Book Chapter Structure-based Drug Design and NMR-based screeningCraik, D. J. and Clark, R. J. (2008). Structure-based Drug Design and NMR-based screening. Pharmacology from drug development to gene therapy. (pp. 225-313) edited by R. A. Meyers. Weinheim: Wiley-VCH Verlag GMBH & Co. |
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2008 Journal Article Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2Aboye, T, Clark, Richard J., Craik, David J. and Goransson, U (2008). Utlra-stable peptide scaffolds for protein engineering synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. ChemBioChem, 9 (1), 103-113. doi: 10.1002/cbic.200700357 |
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2008 Conference Publication Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 30th European Peptide Symposium (30EPS), Helsinki, Finland, 31 August – 5 September 2008. United Kingdom: John Wiley & Sons Ltd.. doi: 10.1002/psc.1090 |
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2008 Conference Publication Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2Aboye, Teshome, Clark, Richard, Craik, David J. and Goransson, Ulf (2008). Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, 3-8 August 2008. Germany: Georg Thieme Verlag. |
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2008 Conference Publication Structural Aspects of Hepcidin-Ferroportin BindingPreza, G, Fernandes, A, Clark, RJ, Craik, DJ, Ganz, T and Nemeth, E (2008). Structural Aspects of Hepcidin-Ferroportin Binding. 50th Annual Meeting of the American- Society-of-Hematology, San Francisco Ca, Dec 06-09, 2008. WASHINGTON: AMER SOC HEMATOLOGY. |
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2008 Journal Article Cyclotides and conotoxins ultra-stable disulfide-rich peptidesCraik, David J., Clark, Richard J. and Daly, Norelle L. (2008). Cyclotides and conotoxins ultra-stable disulfide-rich peptides. Chimica Oggi -Chemistry Today, 26 (4), 20-22. |
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2007 Journal Article Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?Nevin, Simon T., Clark, Richard J., Klimis, H., Christie, M. J., Craik, David J. and Adams, David J. (2007). Are alpha 9 alpha 10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?. Molecular Pharmacology, 72 (6), 1406-1410. doi: 10.1124/mol.107.040568 |
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2007 Journal Article Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamicsJin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T., Tan, Chia Chia, Clark, Richard J., Adams, David J., Alewood, Paul F., Craik, David J. and Daly, Norelle L. (2007). Structure of alpha-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Structural Biology, 7 (28) 28, 1-13. doi: 10.1186/1472-6807-7-28 |
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2007 Journal Article Potential therapeutic applications of the cyclotides and related cystine knot mini-proteinsCraik, D. J, Clark, R. J and Daly, N. L (2007). Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins. Expert Opinion On Investigational Drugs, 16 (5), 595-604. doi: 10.1517/13543784.16.5.595 |
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2007 Journal Article The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitroGunasekera, S, Daly, NL, Clark, RJ, Simonsen, SM, Foley, FM, Saska, I, Lin, F, Wade, JD, Anderson, MA and Craik, DJ (2007). The conserved N-terminal repeat of the plant cyclotides does not assist folding of cyclotide precursor in vitro. Biopolymers, 88 (4), 540-540. |
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2007 Journal Article The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptidesPlan, M. R. R, Goransson, U, Clark, R. J, Daly, N. L, Colgrave, M. L and Craik, D.J (2007). The cyclotide fingerprint in Oldenlandia affinis: Elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem, 8 (9), 1001-1011. doi: 10.1002/cbic.200700097 |
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2007 Conference Publication Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptidesGruber, G. W., Cemazar, M., Clark, R., Horibe, T., Renda, R., Anderson, M. A. and Craik, D. J. (2007). Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides. 20th American-Peptide-Society Symposium, Montréal, Canada, 26-30 Jun 2007. Hoboken, N. J., U.S.: John Wiley & Sons. doi: 10.1002/bip.20783 |
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2007 Journal Article A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteinsGruber, C. W, Cemazar, M., Clark, R. .J, Horibe, T, Renda, R. F., Anderson, M. A. and Craik, D. J. (2007). A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins. Journal of Biological Chemistry, 282 (28), 20435-20446. doi: 10.1074/jbc.M700018200 |
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2006 Journal Article The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1Clark, Richard J., Fischer, Harald, Nevin, Simon T., Adams, David J. and Craik, David J. (2006). The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1. Journal of Biological Chemistry, 281 (32), 23254-23263. doi: 10.1074/jbc.M604550200 |
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2006 Journal Article Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motifDaly, N. L., Clark, R. J., Plan, M. R. and Craik, D. J. (2006). Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochemical Journal, 393 (Part 3), 619-626. doi: 10.1042/BJ20051371 |
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2006 Journal Article Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug designClark, R. J., Daly, N. L. and Craik, D. J. (2006). Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal, 394 (Part 1), 85-93. doi: 10.1042/BJ20051691 |
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2006 Journal Article The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffoldDaly, N. L., Chen, Y. K., Foley, F. M., Bansal, P. S., Bharathi, R., Clark, R. J., Sommerhoff, C. P. and Craik, D. J. (2006). The absolute structural requirement for a proline in the P3 '-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold. Journal of Biological Chemistry, 281 (33), 23668-23675. doi: 10.1074/jbc.M601426200 |
