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Professor Elizabeth Krenske
Professor

Elizabeth Krenske

Email: 
Phone: 
+61 7 336 54632

Overview

Background

Professor Elizabeth Krenske leads a computational chemistry laboratory that specialises in understanding molecular behaviour. Her laboratory has a particular focus on the study of chemical reaction mechanisms, including the computational prediction of reaction outcomes. Prof. Krenske obtained her PhD in synthetic main-group chemistry at The Australian National University's Research School of Chemistry, where she worked with Professor Bruce Wild. After two years of postdoctoral research at the ANU she was awarded a Fulbright Postdoctoral Scholarship and spent two years at the University of California, Los Angeles, working in the field of theoretical and computational chemistry with Professor Kendall Houk. She returned to Australia in 2009 as an ARC Australian Postdoctoral Fellow at the University of Melbourne, and moved to The University of Queensland in 2012 as an ARC Future Fellow. She is currently a Professor in the UQ School of Chemistry and Molecular Biosciences.

Prof. Krenske is a Fellow of the Royal Australian Chemical Institute, Fellow of the Royal Society of Chemistry, Fellow of the Higher Education Academy and former Associate Editor of the RSC journal Organic & Biomolecular Chemistry.

Availability

Professor Elizabeth Krenske is:
Available for supervision

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, Australian National University

Works

Search Professor Elizabeth Krenske’s works on UQ eSpace

130 works between 2002 and 2024

1 - 20 of 130 works

Featured

2024

Journal Article

Diastereo‐ and Enantioselective Construction of Stereochemical Arrays Exploiting Non‐Classical Hydrogen Bonding in Enolborates

Li, Matthew Tin-lok, Scheeff, Stephan, Chen, Jiahua, Johnston, Ryne C., Rizzo, Antonio, Krenske, Elizabeth H. and Chiu, Pauline (2024). Diastereo‐ and Enantioselective Construction of Stereochemical Arrays Exploiting Non‐Classical Hydrogen Bonding in Enolborates. Chemistry – A European Journal, 30 (46) e202401485, e202401485. doi: 10.1002/chem.202401485

Diastereo‐ and Enantioselective Construction of Stereochemical Arrays Exploiting Non‐Classical Hydrogen Bonding in Enolborates

Featured

2024

Journal Article

Data-efficient, chemistry-aware machine learning predictions of Diels-Alder reaction outcomes

Keto, Angus, Guo, Taicheng, Underdue, Morgan, Stuyver, Thijs, Coley, Connor W, Zhang, Xiangliang, Krenske, Elizabeth H. and Wiest, Olaf (2024). Data-efficient, chemistry-aware machine learning predictions of Diels-Alder reaction outcomes. Journal of the American Chemical Society, 146 (23), 16052-16061. doi: 10.1021/jacs.4c03131

Data-efficient, chemistry-aware machine learning predictions of Diels-Alder reaction outcomes

Featured

2024

Journal Article

Dearomative Intramolecular (4+3) Cycloadditions of Thiophenes

Zheng, Yufen, Chen, Yueyao, He, Yuxuan, Rizzo, Antonio, Zhou, Yuchen, Low, Kam-Hung, Krenske, Elizabeth H. and Chiu, Pauline (2024). Dearomative Intramolecular (4+3) Cycloadditions of Thiophenes. Angewandte Chemie, 63 (33) e202407059, e202407059. doi: 10.1002/ange.202407059

Dearomative Intramolecular (4+3) Cycloadditions of Thiophenes

Featured

2023

Journal Article

Mechanistic aspects of thiol additions to Michael acceptors: insights from computations

Roseli, Ras Baizureen, Keto, Angus B. and Krenske, Elizabeth H. (2023). Mechanistic aspects of thiol additions to Michael acceptors: insights from computations. WIREs Computational Molecular Science, 13 (2) e1636, 1-16. doi: 10.1002/wcms.1636

Mechanistic aspects of thiol additions to Michael acceptors: insights from computations

Featured

2022

Journal Article

Chemoselective and diastereoselective intramolecular (3+2) cycloadditions of epoxy and aziridinyl enolsilanes

Chen, Yueyao, Ling, Jesse, Keto, Angus B., He, Yun, Low, Kam‐Hung, Krenske, Elizabeth H. and Chiu, Pauline (2022). Chemoselective and diastereoselective intramolecular (3+2) cycloadditions of epoxy and aziridinyl enolsilanes. Angewandte Chemie International Edition, 61 (21) e202116099, 1-7. doi: 10.1002/anie.202116099

Chemoselective and diastereoselective intramolecular (3+2) cycloadditions of epoxy and aziridinyl enolsilanes

2024

Journal Article

Conformational Sampling in Computational Studies of Natural Products: Why Is It Important?

Zhou, Yuchen, Limbu, Ingso, Garson, Mary J. and Krenske, Elizabeth H. (2024). Conformational Sampling in Computational Studies of Natural Products: Why Is It Important?. Journal of Natural Products. doi: 10.1021/acs.jnatprod.4c00852

Conformational Sampling in Computational Studies of Natural Products: Why Is It Important?

2024

Journal Article

Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside

See, Nicholas W., Roseli, Ras Baizureen, Wimmer, Norbert, Le, Tri T., Krenske, Elizabeth H. and Ferro, Vito (2024). Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside. Chemistry – A European Journal, 30 (52) e202400331. doi: 10.1002/chem.202400331

Origins of temperature‐dependent anomeric selectivity in glycosylations with an L‐idose thioglycoside

2024

Journal Article

Highly Stable Red Emissive Organic Semiconductor Materials with Low Amplified Spontaneous Emission Thresholds

Rahane, Vijay P., Roseli, Ras Baizureen, Ireland, Alexander R., Gale, Innes, Shukla, Atul, Moore, Evan G., Krenske, Elizabeth H., Namdas, Ebinazar B., Jain, Nidhi and Lo, Shih‐Chun (2024). Highly Stable Red Emissive Organic Semiconductor Materials with Low Amplified Spontaneous Emission Thresholds. Advanced Optical Materials, 12 (25) 2400892. doi: 10.1002/adom.202400892

Highly Stable Red Emissive Organic Semiconductor Materials with Low Amplified Spontaneous Emission Thresholds

2024

Journal Article

Reassignment of the structure of a tryptophan‐containing cyclic tripeptide produced by the biarylitide crosslinking cytochrome P450blt

Coe, Laura J., Zhao, Yongwei, Padva, Leo, Keto, Angus, Schittenhelm, Ralf, Tailhades, Julien, Pierens, Greg, Krenske, Elizabeth H., Crüsemann, Max, De Voss, James and Cryle, Max J. (2024). Reassignment of the structure of a tryptophan‐containing cyclic tripeptide produced by the biarylitide crosslinking cytochrome P450blt. Chemistry: A European Journal, 30 (38) e202400988. doi: 10.1002/chem.202400988

Reassignment of the structure of a tryptophan‐containing cyclic tripeptide produced by the biarylitide crosslinking cytochrome P450blt

2024

Journal Article

Low amplified spontaneous emission threshold from solution processable excited‐state intramolecular proton transfer chromophores

Rahane, Vijay P., Shukla, Atul, Roseli, Ras Baizureen, Ireland, Alexander R., Gale, Innes, Krenske, Elizabeth H., Moore, Evan G., Namdas, Ebinazar B., Jain, Nidhi and Lo, Shih‐Chun (2024). Low amplified spontaneous emission threshold from solution processable excited‐state intramolecular proton transfer chromophores. Advanced Optical Materials, 12 (24). doi: 10.1002/adom.202400840

Low amplified spontaneous emission threshold from solution processable excited‐state intramolecular proton transfer chromophores

2024

Journal Article

Binding of the plant-derived toxin simplexin to bovine protein kinase C: insights from molecular dynamics

Zhou, Yuchen, Roseli, Ras Baizureen, Hungerford, Natasha L., Fletcher, Mary T., Ouwerkerk, Diane, Gilbert, Rosalind A. and Krenske, Elizabeth H. (2024). Binding of the plant-derived toxin simplexin to bovine protein kinase C: insights from molecular dynamics. Organic and Biomolecular Chemistry, 22 (14), 2863-2876. doi: 10.1039/d4ob00065j

Binding of the plant-derived toxin simplexin to bovine protein kinase C: insights from molecular dynamics

2024

Journal Article

Revisiting Staudinger and Ruzicka’s altered pyrethrolone: the cyclopentadienone dimers derived from pyrethrin I, cinerin I and jasmolin I

Hutt, Oliver E., Freemont, Jamie A., Kyi, Stella, Littler, Stuart W., McGeary, Ross P., Duggan, Peter J., Tsanaktsidis, John, Cole, Helen F., Kerr, Maurice G., Krenske, Elizabeth H. and Ryan, John H. (2024). Revisiting Staudinger and Ruzicka’s altered pyrethrolone: the cyclopentadienone dimers derived from pyrethrin I, cinerin I and jasmolin I. Australian Journal of Chemistry, 77 (3) CH23197. doi: 10.1071/ch23197

Revisiting Staudinger and Ruzicka’s altered pyrethrolone: the cyclopentadienone dimers derived from pyrethrin I, cinerin I and jasmolin I

2024

Journal Article

Structural insights into a side chain cross-linking Biarylitide P450 from RiPP biosynthesis

Hansen, Mathias H., Keto, Angus, Treisman, Maxine, Sasi, Vishnu Mini, Coe, Laura, Zhao, Yongwei, Padva, Leo, Hess, Caroline, Leichthammer, Victor, Machell, Daniel L., Schittenhelm, Ralf B., Jackson, Colin J., Tailhades, Julien, Crüsemann, Max, De Voss, James J., Krenske, Elizabeth H. and Cryle, Max J. (2024). Structural insights into a side chain cross-linking Biarylitide P450 from RiPP biosynthesis. ACS Catalysis, 14 (2), 812-826. doi: 10.1021/acscatal.3c05417

Structural insights into a side chain cross-linking Biarylitide P450 from RiPP biosynthesis

2024

Journal Article

Co(<scp>iii</scp>) complexes of the pentadentate NHC ligand PY4Im: carbene-induced <i>trans</i> influences and the non-disappearing <sup>13</sup>C NMR peak

Ismael, Fouad, Fleming, Cassandra L., Christopher, Timothy D., Söhnel, Tilo, Zhou, Yuchen, Krenske, Elizabeth H., Gahan, Lawrence R. and Blackman, Allan G. (2024). Co(iii) complexes of the pentadentate NHC ligand PY4Im: carbene-induced trans influences and the non-disappearing 13C NMR peak. Dalton Transactions, 53 (30), 12688-12697. doi: 10.1039/d4dt01579g

Co(<scp>iii</scp>) complexes of the pentadentate NHC ligand PY4Im: carbene-induced <i>trans</i> influences and the non-disappearing <sup>13</sup>C NMR peak

2023

Journal Article

Light blue rigid excited-state intramolecular proton transfer organic semiconductor laser chromophores

Allison, Ilene, Mamada, Mashashi, Shukla, Atul, McGregor, Sarah K. M., Roseli, Ras Baizureen, Gale, Innes, Rahane, Vijay P., Moore, Evan G., Krenske, Elizabeth H., Jain, Nidhi, Adachi, Chihaya, Namdas, Ebinazar B. and Lo, Shih-Chun (2023). Light blue rigid excited-state intramolecular proton transfer organic semiconductor laser chromophores. Journal of Materials Chemistry C, 11 (45), 15861-15872. doi: 10.1039/d3tc02707d

Light blue rigid excited-state intramolecular proton transfer organic semiconductor laser chromophores

2023

Journal Article

C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity

See, Nicholas W., Pierens, Gregory K., Krenske, Elizabeth and Ferro, Vito (2023). C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity. Synthesis, 56 (06), 966-974. doi: 10.1055/a-2149-4586

C-5 epimerisation of D-mannopyranosyl fluorides: the influence of anomeric configuration on radical reactivity

2023

Journal Article

The oxidation of oxygen and sulfur‐containing heterocycles by cytochrome P450 enzymes

Podgorski, Matthew N, Keto, Angus B, Coleman, Tom, Bruning, John B, De Voss, James J, Krenske, Elizabeth H and Bell, Stephen Graham (2023). The oxidation of oxygen and sulfur‐containing heterocycles by cytochrome P450 enzymes. Chemistry – A European Journal, 29 (50) e202301371, e202301371. doi: 10.1002/chem.202301371

The oxidation of oxygen and sulfur‐containing heterocycles by cytochrome P450 enzymes

2023

Journal Article

Synthesis, characterization and computational investigation of the phosphatase activity of a dinuclear Zinc(II) complex containing a new heptadentate asymmetric ligand

Costa, Luel M.O., Reis, Iago S., Fernandes, Christiane, Marques, Marcelo M., Resende, Jackson A.L.C., Krenske, Elizabeth H., Schenk, Gerhard, Gahan, Lawrence R. and Horn, Adolfo (2023). Synthesis, characterization and computational investigation of the phosphatase activity of a dinuclear Zinc(II) complex containing a new heptadentate asymmetric ligand. Journal of Inorganic Biochemistry, 239 112064, 1-13. doi: 10.1016/j.jinorgbio.2022.112064

Synthesis, characterization and computational investigation of the phosphatase activity of a dinuclear Zinc(II) complex containing a new heptadentate asymmetric ligand

2023

Journal Article

The mechanism of cleavage of Evans chiral auxiliaries by LiOOH: origins of the different regioselectivities obtained with LiOH, LiOOH, LiOBn and LiSBn

Chow, Ka Ho, Quinn, Ronald J., Jenkins, Ian D. and Krenske, Elizabeth H. (2023). The mechanism of cleavage of Evans chiral auxiliaries by LiOOH: origins of the different regioselectivities obtained with LiOH, LiOOH, LiOBn and LiSBn. Australian Journal of Chemistry, 76 (12), 847-853. doi: 10.1071/ch23086

The mechanism of cleavage of Evans chiral auxiliaries by LiOOH: origins of the different regioselectivities obtained with LiOH, LiOOH, LiOBn and LiSBn

2022

Journal Article

Enabling aromatic hydroxylation in a cytochrome P450 monooxygenase rnzyme through protein engineering

Coleman, Tom, Lee, Joel, Kirk, Alicia M, Doherty, Daniel Z, Podgorski, Matthew N, Pinidiya, Dilshi K, Bruning, John B, De Voss, James J, Krenske, Elizabeth H and Bell, Stephen Graham (2022). Enabling aromatic hydroxylation in a cytochrome P450 monooxygenase rnzyme through protein engineering. Chemistry: A European Journal, 28 (67) e202201895, 1-14. doi: 10.1002/chem.202201895

Enabling aromatic hydroxylation in a cytochrome P450 monooxygenase rnzyme through protein engineering

Funding

Current funding

  • 2022 - 2025
    Opening Up Access to L-Sugars through a Synergy of Experiment and Theory
    ARC Discovery Projects
    Open grant

Past funding

  • 2018 - 2022
    Computational Tools for Organic Synthesis
    ARC Discovery Projects
    Open grant
  • 2017 - 2020
    New Computational Technology to Drive Innovation in Molecular Science
    UQ Development Fellowships
    Open grant
  • 2017 - 2021
    Large area opto-electronics for Australia and India: from materials to advanced devices
    Department of Industry, Innovation, and Science - Australia-India Strategic Research Fund
    Open grant
  • 2015 - 2017
    Chiral Catalysts by Rational Design (ARC Discovery Project administered by Monash University)
    Monash University
    Open grant
  • 2014
    A parallel computer facility for modelling and simulation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2017
    Theoretical modelling and design of safe covalent anti-cancer drugs
    ARC Future Fellowships
    Open grant

Supervision

Availability

Professor Elizabeth Krenske is:
Available for supervision

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Available projects

  • Molecular modelling. Chemical Reactivity. Catalysis. Drug Design.

Supervision history

Current supervision

  • Doctor Philosophy

    Development of new computational techniques for carbohydrate and agricultural chemistry

    Principal Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Synthesis of L-sugars via radical chemistry

    Associate Advisor

    Other advisors: Professor Vito Ferro

Completed supervision

Media

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