Overview
Background
Dr Meihua Yu is a Research Fellow in Cancer Immunotherapy at the Australian Institute for Bioengineering and Nanotechnology (AIBN). She received her PhD in Biomedical Engineering from AIBN, UQ in 2014. Throughout her research career, she has held full-time research positions from 2014 to 2021 at UQ following completion of her PhD, followed by a position as Research-Teaching Associate Prof at Shanghai University, China (2021-2025). She returned to AIBN in 2026 to continue her research program.
Dr Yu's current research focuses on materials-immunology for cancer treatment and prevention of infectious diseases. Dr Yu has published 95 papers (H-index, 40) in top international journals including Science Advances, Angewandte Chemie International Edition, Advanced Materials, Journal of the American Chemical Society, Journal of Immunology, and Chemical Society Reviews. Her innovative research has resulted in 1 international patents and 14 Chinese patents.
Dr Yu has secured competitive research funding over $1.0M from the ARC, NHMRC, Queensland Government, National Natural Science Foundation of China, Shanghai Municipality, and Zhejiang Province (e.g., UQ Early Career grants, ARC Linkage projects, Queensland Biomedical Assistance Fund, and the 2017 UQ Foundation Research Excellence Award).
Dr Yu has been awarded four prestigious national and state fellowships, including 2017 NHMRC Early Career Fellowship, 2016 Advance Queensland Early Career Research Fellowship, 2021 Shanghai Excellent Overseas Young Scientists, and 2022 Zhejiang Overseas Thousand Talents Program (relinquished). She has actively pursued commercial translation of her discoveries through strategic collaborations with industry partners, including Ridley, Ellume, and Jingang Medicines.
Dr Yu serves as an invited reviewer for national competitive grants and manuscripts for more than 40 international journals, including Med, ACS Nano, and Advanced Materials.
Availability
- Dr Meihua Yu is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Meihua Yu’s works on UQ eSpace
2026
Journal Article
Enzyme-triggered self-immobilization of an NIR prodrug for tumor-selective cancer vaccination
Li, Yuyao, Ren, Hongze, Feng, Jiayi, Shan, Xiaochuan, Zhang, Chaoying, Nan, Jin, Tang, Zhengqi, Ding, Xueqin, Yu, Meihua, Xie, Hexin and Chen, Yu (2026). Enzyme-triggered self-immobilization of an NIR prodrug for tumor-selective cancer vaccination. Journal of the American Chemical Society, 148 (15), 15655-15671. doi: 10.1021/jacs.5c20321
2026
Journal Article
Hierarchically collapsible nanoactuator modulates mitochondrial ferroptosis-bioenergetic homeostasis cascade to decouple ischemic stroke
Sun, Guangjie, Dong, Yize, Wang, Ying, Su, Yihong, Chen, Jiajun, Deng, Jiali, Luo, Lan, Cao, Xinyue, Lu, Weiping, Chen, Kai, Yu, Meihua, Xie, Yujie, Huang, Bingcang and Chen, Yu (2026). Hierarchically collapsible nanoactuator modulates mitochondrial ferroptosis-bioenergetic homeostasis cascade to decouple ischemic stroke. Cell reports Medicine, 7 (3) 102640, 102640. doi: 10.1016/j.xcrm.2026.102640
2026
Journal Article
Self‐assembled two‐dimensional chiral meso‐topography determines the balance of cellular and humoral immunity against tumors
Dong, Lingkai, Yang, Wei, Li, Xingjin, Ma, Yanming, Huang, Xirui, Fan, Yu, Cao, Nan, Lu, Qianqian, Zhan, Yating, Shen, Jiacheng, Liu, Minchao, Chen, Liang, Chen, Yu, Yu, Meihua, Zhao, Tiancong and Zhao, Dongyuan (2026). Self‐assembled two‐dimensional chiral meso‐topography determines the balance of cellular and humoral immunity against tumors. Advanced Materials, 38 (12) e20552. doi: 10.1002/adma.202520552
2026
Journal Article
Self-assembled metal-polyphenol colchicine nanoparticles targeting oxidative stress and inflammation for treatment of atherosclerosis
Centurion, Franco, Zhang, Xiuwen, Dai, Chen, Kundi, Varun, Kumar, Priyank, Yu, Meihua, Appadoo, Dominique, Rawal, Aditya, Misra, Ashish, Patel, Sanjay, Chen, Yu and Gu, Zi (2026). Self-assembled metal-polyphenol colchicine nanoparticles targeting oxidative stress and inflammation for treatment of atherosclerosis. Angewandte Chemie (International Edition), 65 (7) e14547, 1-11. doi: 10.1002/anie.202514547
2026
Journal Article
NIR-actuated morphodynamic 2D nanopatches for interface-programmed immunoactivation and tumor regression
Wu, Ye, Jia, Wencong, Xia, Tianlai, Liao, Jing, He, Wenjin, Wang, Huijing, Yang, Wei, Dai, Xinyue, Feng, Wei, O'reilly, Rachel K., Tong, Zaizai, Yu, Meihua, Xie, Yujie and Chen, Yu (2026). NIR-actuated morphodynamic 2D nanopatches for interface-programmed immunoactivation and tumor regression. Journal of the American Chemical Society, 148 (3), 2902-2919. doi: 10.1021/jacs.5c11219
2026
Journal Article
Self‐Assembled Metal‐Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis
Centurion, Franco, Zhang, Xiuwen, Dai, Chen, Kundi, Varun, Kumar, Priyank, Yu, Meihua, Appadoo, Dominique, Rawal, Aditya, Misra, Ashish, Patel, Sanjay, Chen, Yu and Gu, Zi (2026). Self‐Assembled Metal‐Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis. Angewandte Chemie, 138 (7) e14547. doi: 10.1002/ange.202514547
2026
Journal Article
A multifunctional dicyanoisophorone-based fluorescent probe for Zn2+ and pyrophosphate detection: Practical applications in water, living sprout, and cell imaging
Liu, Lu, Luo, Pengwen, Guo, Xunsheng, Yang, Yihan, Chen, Hong, Chen, Xiaoxia, Feng, Yating, Hu, Bin, Xie, Yu and Yu, Meihua (2026). A multifunctional dicyanoisophorone-based fluorescent probe for Zn2+ and pyrophosphate detection: Practical applications in water, living sprout, and cell imaging. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 344 (Part 1) 126699. doi: 10.1016/j.saa.2025.126699
2025
Journal Article
Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment
Nan, Jin, Xia, Chundongqiu, Zhang, Jingyi, Xie, Yujie, Shi, Shuyu, Yang, Wei, Yu, Meihua, Chen, Yu and Zhang, Jun (2025). Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment. Biomaterials, 322 123379, 1-14. doi: 10.1016/j.biomaterials.2025.123379
2025
Journal Article
Dual-locked polymeric STING nano-agonist/sonosensitizer augments spatiotemporally controlled cancer sono-immunotherapy
Jia, Yiwen, Jia, Wencong, Tang, Zhengqi, Wu, Ye, Yang, Wei, Ye, Weifan, Ren, Hongze, Xie, Yujie, Chen, Yu and Yu, Meihua (2025). Dual-locked polymeric STING nano-agonist/sonosensitizer augments spatiotemporally controlled cancer sono-immunotherapy. Angewandte Chemie (International Edition), 64 (44) e202514516, 1-15. doi: 10.1002/anie.202514516
2025
Journal Article
Sono-destructive polymeric nanocapsules enable spatiotemporal orchestration of DC-T cell crosstalk in combined in situ vaccination and cytokine therapy
Jia, Wencong, Yang, Wei, Wu, Ye, Ren, Hongze, Jia, Yiwen, Ye, Weifan, Xie, Yujie, Chen, Yu and Yu, Meihua (2025). Sono-destructive polymeric nanocapsules enable spatiotemporal orchestration of DC-T cell crosstalk in combined in situ vaccination and cytokine therapy. Journal of the American Chemical Society, 147 (29), 25553-25570. doi: 10.1021/jacs.5c06120
2025
Journal Article
Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination
Zhu, Anqi, Ren, Hongze, Li, Xiaolong, Yang, Wei, Han, Xiaoxia, Hou, Xiaodong, Zhang, Shen, Li, Shaoyue, Xie, Yujie, Yu, Meihua, Chen, Yu and Xu, Huixiong (2025). Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination. Nano Today, 61 102590, 102590. doi: 10.1016/j.nantod.2024.102590
2025
Journal Article
Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation
Jia, Wencong, Wu, Ye, Xie, Yujie, Yu, Meihua and Chen, Yu (2025). Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation. Advanced Materials, 37 (8) 2413603, 1-70. doi: 10.1002/adma.202413603
2025
Journal Article
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor
Yang, Wei, Di, Sichen, Yang, Zihuan, Cao, Jianwei, Fu, Qingqiao, Ren, Hongze, Cheng, Hui, Xie, Yujie, Jia, Wencong, Dai, Xinyue, Yu, Meihua, Chen, Yu and Cui, Xingang (2025). One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor. Science Advances, 11 (5) eado7373, 1-23. doi: 10.1126/sciadv.ado7373
2025
Journal Article
Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment
Wang, Huijing, He, Wenjin, Liao, Jing, Wang, Shuangshuang, Dai, Xinyue, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment. Advanced Materials, 37 (1) 2411967, 1-47. doi: 10.1002/adma.202411967
2025
Journal Article
External stimuli-driven catalytic hydrogels for biomedical applications
Liao, Jing, Sun, Jijun, Jia, Wencong, He, Wenjin, Wang, Huijing, Huang, Weiyun, Wang, Yanmei, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). External stimuli-driven catalytic hydrogels for biomedical applications. Chemical Communications, 61 (20), 3946-3966. doi: 10.1039/d4cc05256k
2024
Journal Article
STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines
Jia, Wencong, Chandra, Janin, Teoh, Siok Min, Tolley, Lynn, Yang, Haotian, Tse, Brian W. C., Sokolowski, Kamil A., Liang, Xiaowen, Crawford, Darrell H. G., Steel, Jason C., Yu, Chengzhong, Roberts, Michael S., Frazer, Ian H., Chen, Yu, Wang, Haolu and Yu, Meihua (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24 (49), 1-10. doi: 10.1021/acs.nanolett.4c03846
2024
Journal Article
2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor
Ren, Hongze, Zhu, Anqi, Yang, Wei, Jia, Yiwen, Cheng, Hui, Wu, Ye, Tang, Zhengqi, Ye, Weifan, Sun, Mayu, Xie, Yujie, Yu, Meihua and Chen, Yu (2024). 2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor. Advanced Science, 11 (40) 2405729. doi: 10.1002/advs.202405729
2024
Journal Article
Immuno-nanocomplexes target heterogenous network of inflammation and immunity in myocardial infarction
Su, Fan, Ye, Weifan, Shen, Yi, Xie, Yujie, Zhang, Chong, Zhang, Qianyun, Tang, Zhengqi, Yu, Meihua, Chen, Yu and He, Bin (2024). Immuno-nanocomplexes target heterogenous network of inflammation and immunity in myocardial infarction. Advanced Science, 11 (36) 2402267. doi: 10.1002/advs.202402267
2024
Journal Article
Immunogenic material vaccine for cancer immunotherapy by structure‐dependent immune cell trafficking and modulation
Yang, Wei, Cao, Jianwei, Di, Sichen, Chen, Wenjin, Cheng, Hui, Ren, Hongze, Xie, Yujie, Chen, Liang, Yu, Meihua, Chen, Yu and Cui, Xingang (2024). Immunogenic material vaccine for cancer immunotherapy by structure‐dependent immune cell trafficking and modulation. Advanced Materials, 36 (27) 2402580. doi: 10.1002/adma.202402580
2024
Journal Article
Engineering nanoprobes for magnetic resonance imaging of brain diseases
Zhang, Jingyi, Yu, Luodan, Yu, Meihua, Yu, Dehong, Chen, Yu and Zhang, Jun (2024). Engineering nanoprobes for magnetic resonance imaging of brain diseases. Chemical Engineering Journal, 481 148472, 1-29. doi: 10.1016/j.cej.2023.148472
Funding
Past funding
Supervision
Availability
- Dr Meihua Yu is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Completed supervision
-
2019
Doctor Philosophy
Development of a Mesoporous Silica Based Nanosystem for Safe and Efficient Therapeutic Delivery
Joint Principal Advisor
Other advisors: Professor Chengzhong Yu
-
2021
Master Philosophy
Development of Silica Based Nanoparticles for Plasmid DNA Delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2020
Doctor Philosophy
Engineered iron-based nanomaterials for macrophage-centred anti-cancer application
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Synthesis and characterization of novel silica nanoparticles for delivery applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2019
Doctor Philosophy
Optimised multifunctionality of Mesoporous Carbon Hollow Spheres (MCHS) nanocarriers using carbonization temperature
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Synthesis of Novel Mesoporous Materials as High-performance Adsorbents
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineering Nanomaterials as Safe and Effective Immune Adjuvants
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2018
Doctor Philosophy
Engineered Silica nanoparticles for efficient biomolecules delivery
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2017
Doctor Philosophy
Mesoporous silica nanoparticles for biomedical application
Associate Advisor
Other advisors: Professor Amirali Popat, Professor Chengzhong Yu
-
2016
Doctor Philosophy
Design of Mesoporous Silica Nanoparticles as Drug Carriers
Associate Advisor
Other advisors: Professor Chengzhong Yu
-
2016
Master Philosophy
Designed synthesis of large pore mesoporous silica nanoparticles as nano-carriers for bio-applications
Associate Advisor
Other advisors: Professor Chengzhong Yu
Media
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