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Dr Meihua Yu
Dr

Meihua Yu

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Overview

Background

Dr Meihua Yu is a NHMRC Early Career Fellow in Prof Ian Frazer’s lab, University Queensland Diamantina Institute (UQDI). She received her PhD degree in Biomedical Engineering from the Australian Institute for Bioengineering and Nanotechnology (AIBN), UQ in 2014, under the guidance of Prof Chengzhong (Michael) Yu.

Dr Yu’s current research focuses on developing nanotechnology vaccines for the treatment of diseases and cancers. She has extensive experience in development of sophisticated nanotechnology with controllable architecture, composition and functionality, and delivery of anticancer drugs, genetic molecules and therapeutic proteins for enhanced cancer treatment.

Dr Yu was awarded two prestigious fellowships (Advance Queensland Research Fellow in 2016 and a NHMRC Early Career Fellow in 2017). She has secured over $1.2 million in funding from internal and external funding agencies (UQ Early Career grant, ARC Linkage, Queensland Biomedical Assistance Fund). In recognition of her research achievements, she was awarded the prestigious 2017 UQ Foundation Research Excellence Award, the 2017 Monash Engineering Women Leader Award and the 2018 Frazer Family Foundation Travel Award.

Dr Yu has published 59 papers in international top refereed journals such as Journal of the American Chemical Society, Small, Chemical Communications, Nanoscale, and so on. Her innovative research has led to three patents. She has actively explored the potential of these discoveries in commercial translation by engaging with industry partners (e.g. Ridley, Ellume, Jingang Medicines).

Dr Yu is an invited reviewer for national grants (e.g. ARC DP and ARC DECRA) and 19 journals including Vaccines, ACS Omega, Biomaterials Science and Journal of Hazardous Materials.

Availability

Dr Meihua Yu is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Meihua Yu’s works on UQ eSpace

154 works between 2006 and 2026

1 - 20 of 154 works

2026

Journal Article

Self-Assembled Metal-Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis

Centurion, Franco, Zhang, Xiuwen, Dai, Chen, Kundi, Varun, Kumar, Priyank, Yu, Meihua, Appadoo, Dominique, Rawal, Aditya, Misra, Ashish, Patel, Sanjay, Chen, Yu and Gu, Zi (2026). Self-Assembled Metal-Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis. Angewandte Chemie-International Edition, 65 (7) PMID 370543. doi: 10.1002/anie.202514547

Self-Assembled Metal-Polyphenol Colchicine Nanoparticles Targeting Oxidative Stress and Inflammation for Treatment of Atherosclerosis

2025

Journal Article

Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment

Nan, Jin, Xia, Chundongqiu, Zhang, Jingyi, Xie, Yujie, Shi, Shuyu, Yang, Wei, Yu, Meihua, Chen, Yu and Zhang, Jun (2025). Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment. Biomaterials, 322 123379, 1-14. doi: 10.1016/j.biomaterials.2025.123379

Gadolinium-ceria hybrid system enables synergistic alleviation of oxidative stress and metabolic thrombo-inflammation for efficient ischemic stroke treatment

2025

Journal Article

Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination

Zhu, Anqi, Ren, Hongze, Li, Xiaolong, Yang, Wei, Han, Xiaoxia, Hou, Xiaodong, Zhang, Shen, Li, Shaoyue, Xie, Yujie, Yu, Meihua, Chen, Yu and Xu, Huixiong (2025). Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination. Nano Today, 61 102590. doi: 10.1016/j.nantod.2024.102590

Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination

2025

Journal Article

DNA origami-based composite nanosandwich for iteratively potentiated chemo-immunotherapy

Li, Mengyue, Zhang, Hanxi, Xiong, Peizheng, He, Yuhan, Zhou, Wanyi, Wu, Chunhui, Liao, Xiaoling, Zhang, Wei, Yang, Hong and Liu, Yiyao (2025). DNA origami-based composite nanosandwich for iteratively potentiated chemo-immunotherapy. Journal of Controlled Release, 379, 452-465. doi: 10.1016/j.jconrel.2025.01.031

DNA origami-based composite nanosandwich for iteratively potentiated chemo-immunotherapy

2025

Journal Article

Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation

Jia, Wencong, Wu, Ye, Xie, Yujie, Yu, Meihua and Chen, Yu (2025). Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation. Advanced Materials, 37 (8) 2413603, 1-70. doi: 10.1002/adma.202413603

Advanced polymeric nanoparticles for cancer immunotherapy: materials engineering, immunotherapeutic mechanism and clinical translation

2025

Journal Article

One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor

Yang, Wei, Di, Sichen, Yang, Zihuan, Cao, Jianwei, Fu, Qingqiao, Ren, Hongze, Cheng, Hui, Xie, Yujie, Jia, Wencong, Dai, Xinyue, Yu, Meihua, Chen, Yu and Cui, Xingang (2025). One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor. Science Advances, 11 (5) eado7373, 1-23. doi: 10.1126/sciadv.ado7373

One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor

2025

Journal Article

A digital twin system for rock triaxial mechanical tests incorporating probabilistic parameter updates and model prediction through data assimilation technique

Lyu, Changhao, Xu, Weiya, Wang, Haijiang, Wu, Yizhe and Wang, Huanling (2025). A digital twin system for rock triaxial mechanical tests incorporating probabilistic parameter updates and model prediction through data assimilation technique. Rock Mechanics and Rock Engineering, 58 (5), 5845-5860. doi: 10.1007/s00603-025-04406-x

A digital twin system for rock triaxial mechanical tests incorporating probabilistic parameter updates and model prediction through data assimilation technique

2025

Journal Article

Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment

Wang, Huijing, He, Wenjin, Liao, Jing, Wang, Shuangshuang, Dai, Xinyue, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment. Advanced Materials, 37 (1) 2411967, 1-47. doi: 10.1002/adma.202411967

Catalytic biomaterials-activated in situ chemical reactions: Strategic modulation and enhanced disease treatment

2025

Journal Article

External stimuli-driven catalytic hydrogels for biomedical applications

Liao, Jing, Sun, Jijun, Jia, Wencong, He, Wenjin, Wang, Huijing, Huang, Weiyun, Wang, Yanmei, Yu, Meihua, Xie, Yujie and Chen, Yu (2025). External stimuli-driven catalytic hydrogels for biomedical applications. Chemical Communications, 61 (20), 3946-3966. doi: 10.1039/d4cc05256k

External stimuli-driven catalytic hydrogels for biomedical applications

2024

Journal Article

Deterioration mechanism and statistical damage constitutive model of red-bed soft rock with different moisture content

Wu, Yizhe, Wang, Huanling, Zhang, Yanjie, Lyu, Changhao, Liu, Yuxuan and Wang, Wenxiu (2024). Deterioration mechanism and statistical damage constitutive model of red-bed soft rock with different moisture content. Pure and Applied Geophysics, 182 (1), 189-208. doi: 10.1007/s00024-024-03609-7

Deterioration mechanism and statistical damage constitutive model of red-bed soft rock with different moisture content

2024

Journal Article

R(3780) resonance interpreted as the 13D1-wave dominant state of charmonium from precise measurements of the cross section of e+ e- → hadrons

Ablikim, M., Achasov, M. N., Adlarson, P., Ai, X. C., Aliberti, R., Amoroso, A., An, M. R., An, Q., Bai, Y., Bakina, O., Balossino, I., Ban, Y., Batozskaya, V., Begzsuren, K., Berger, N., Berlowski, M., Bertani, M., Bettoni, D., Bianchi, F., Bianco, E., Bloms, J., Bortone, A., Boyko, I., Briere, R. A., Brueggemann, A., Cai, H., Cai, X., Calcaterra, A., Cao, G. F. ... Zu, J. (2024). R(3780) resonance interpreted as the 13D1-wave dominant state of charmonium from precise measurements of the cross section of e+ e- → hadrons. Physical Review Letters, 133 (24) 241902, 1-10. doi: 10.1103/PhysRevLett.133.241902

R(3780) resonance interpreted as the 13D1-wave dominant state of charmonium from precise measurements of the cross section of e+ e- → hadrons

2024

Journal Article

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

Jia, Wencong, Chandra, Janin, Teoh, Siok Min, Tolley, Lynn, Yang, Haotian, Tse, Brian W. C., Sokolowski, Kamil A., Liang, Xiaowen, Crawford, Darrell H. G., Steel, Jason C., Yu, Chengzhong, Roberts, Michael S., Frazer, Ian H., Chen, Yu, Wang, Haolu and Yu, Meihua (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24 (49), 1-10. doi: 10.1021/acs.nanolett.4c03846

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

2024

Journal Article

Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasu's arteritis

Fang, Chenglong, Du, Lihong, Gao, Shang, Chen, Yuexin, Chen, Zuoguan, Wu, Zhiyuan, Li, Lili, Li, Jing, Zeng, Xiaofeng, Li, Mengtao, Li, Yongjun and Tian, Xinping (2024). Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasu's arteritis. Annals of the Rheumatic Diseases, 83 (11), 1522-1535. doi: 10.1136/ard-2024-225630

Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasu's arteritis

2024

Conference Publication

Angiography-Derived Radial Wall Strain Predicts Efficacy of Drug-Coated Balloon Angioplasty for De Novo Small Vessel Disease: Insights From the PEPCAD China SVD Study

Xu, Ke, Fu, Xi, Wu, Yizhe, Wang, Zhiqing, Chu, Miao, Qian, Juying, He, Ben, Tu, Shengxian, Shen, Linghong and Ge, Junbo (2024). Angiography-Derived Radial Wall Strain Predicts Efficacy of Drug-Coated Balloon Angioplasty for De Novo Small Vessel Disease: Insights From the PEPCAD China SVD Study. 36th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Washington Dc, Oct 27-30, 2024. NEW YORK: ELSEVIER SCIENCE INC.

Angiography-Derived Radial Wall Strain Predicts Efficacy of Drug-Coated Balloon Angioplasty for De Novo Small Vessel Disease: Insights From the PEPCAD China SVD Study

2024

Conference Publication

Five-Year Clinical Outcomes of Patients Treated With the Xinsorb Bioresorbable Sirolimus-Eluting Scaffolds

Yin, Jiasheng, Xu, Qiang, Wu, Yizhe, Chen, Jiahui, Shen, Li, Qian, Juying, Ge, Lei and Ge, Junbo (2024). Five-Year Clinical Outcomes of Patients Treated With the Xinsorb Bioresorbable Sirolimus-Eluting Scaffolds. 36th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Washington Dc, Oct 27-30, 2024. NEW YORK: ELSEVIER SCIENCE INC.

Five-Year Clinical Outcomes of Patients Treated With the Xinsorb Bioresorbable Sirolimus-Eluting Scaffolds

2024

Conference Publication

Multi-omics integration analysis identifies pathogenic candidate genes of congenital heart defects with vascular malformation

Ding, X. W., Huang, J. X., Chen, Y. H., Li, Z. Y., Wu, Y. Z., Qian, Z. L., Feng, W. Q., Li, Y. R., Zhao, L. D., Zhao, P. J., Lu, Y. N. and Yu, Y. (2024). Multi-omics integration analysis identifies pathogenic candidate genes of congenital heart defects with vascular malformation. European-Society-of-Cardiology Congress (ESC), London England, Aug 30-Sep 02, 2024. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/eurheartj/ehae666.2109

Multi-omics integration analysis identifies pathogenic candidate genes of congenital heart defects with vascular malformation

2024

Journal Article

2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor

Ren, Hongze, Zhu, Anqi, Yang, Wei, Jia, Yiwen, Cheng, Hui, Wu, Ye, Tang, Zhengqi, Ye, Weifan, Sun, Mayu, Xie, Yujie, Yu, Meihua and Chen, Yu (2024). 2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor. Advanced Science, 11 (40) 2405729. doi: 10.1002/advs.202405729

2D differential metallic immunopotentiators drive high diversity and capability of antigen-specific immunity against tumor

2024

Journal Article

Study of the decay and production properties of Ds1 (2536) and Ds2* (2573)

Ablikim, M., Achasov, M. N., Adlarson, P., Afedulidis, O., Ai, X. C., Aliberti, R., Amoroso, A., An, Q., Bai, Y., Bakina, O., Balossino, I., Ban, Y., Bao, H. -R., Batozskay, V., Begzsuren, K., Berger, N., Berlowski, M., Bertani, M., Bettoni, D., Bianchi, F., Bianco, E., Bortone, A., Boyko, I., Briere, R. A., Brueggemann, A., Cai, H., Cai, X., Calcaterra, A., Cao, G. F. ... Zu, J. (2024). Study of the decay and production properties of Ds1 (2536) and Ds2* (2573). Physical Review Letters, 133 (17) 171903, 1-10. doi: 10.1103/PhysRevLett.133.171903

Study of the decay and production properties of Ds1 (2536) and Ds2* (2573)

2024

Journal Article

Search for the exclusive W boson hadronic decays W± → π±γ, W± → K±γ and W± → ρ±γ with the ATLAS Detector

Aad, G., Abbott, B., Abeling, K., Abicht, N. J., Abidi, S. H., Aboulhorma, A., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Bourdarios, C. Adam, Adamczyk, L., Addepalli, S. V., Addison, M. J., Adelman, J., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agaras, M. N., Agarwala, J., Aggarwal, A., Agheorghiesei, C., Ahmad, A., Ahmadov, F., Ahmed, W. S., Ahuja, S., Ai, X., Aielli, G. ... Zwalinski, L. (2024). Search for the exclusive W boson hadronic decays W± → π±γ, W± → K±γ and W± → ρ±γ with the ATLAS Detector. Physical Review Letters, 133 (16) 161804, 1-23. doi: 10.1103/PhysRevLett.133.161804

Search for the exclusive W boson hadronic decays W± → π±γ, W± → K±γ and W± → ρ±γ with the ATLAS Detector

2024

Journal Article

Hydrogen sulphide reduces renal ischemia-reperfusion injury by enhancing autophagy and reducing oxidative stress

Li, Hui, Wang, Shuaiwei, An, Shuangshuang, Gao, Biao, Wu, Dongdong and Li, Yanzhang (2024). Hydrogen sulphide reduces renal ischemia-reperfusion injury by enhancing autophagy and reducing oxidative stress. Nephrology, 29 (10), 645-654. doi: 10.1111/nep.14368

Hydrogen sulphide reduces renal ischemia-reperfusion injury by enhancing autophagy and reducing oxidative stress

Funding

Past funding

  • 2018 - 2022
    A Nano-platform for Affordable and Ultra-sensitive Bio-marker Detection
    ARC Linkage Projects
    Open grant
  • 2018
    Assessment of Novel Nanoadjuvants for the Development of Potent Therapeutic Cancer Vaccines
    UQ Foundation
    Open grant
  • 2018
    Nanotechnology-medicated therapeutic HPV DNA vaccines
    UQ Early Career Researcher
    Open grant
  • 2017 - 2020
    Engineered Spiky Silica Nanoparticles as Effective Immune Adjuvants by Activating Inflammasome and Enhancing Cellular Uptake
    NHMRC Early Career Fellowships
    Open grant
  • 2016
    Advance Queensland Research Fellowship (Early): Nano-pollen encapsulated lysozyme: a safe alternative to antibiotics for livestock
    Advance Queensland Research Fellowships
    Open grant
  • 2012 - 2013
    A general platform technology for functional nanocomposites with advanced applications
    UWA-UQ Bilateral Research Collaboration Award
    Open grant

Supervision

Availability

Dr Meihua Yu is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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