Dr Lesley Lluka
Dr

Lesley Lluka

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Background

Transporters for Catecholamines and Serotonin. Science Education.

The overall theme of Lesley Lluka's research over 3 decades has been the structure and function of the noradrenaline transporter (NET) and the serotonin transporter (SERT). These transporters are important sites of action of drugs such as antidepressants.

More recently, Lesley Lluka's work has increasingly moved to Science Education, with a focus on areas such as student engagement in practical classes, innovative assessment practices to drive deep learning, and internationalization of the curriculum.

Availability

Dr Lesley Lluka is:
Not available for supervision

Fields of research

Clinical sciences Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Pharmacy, The University of Queensland
  • Masters (Coursework), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research interests

  • Internationalisation of the curriculum in biomedical science

  • Role of tutor training in determining student learning outcomes

  • Vertically integrated practical curriculum in physiology

  • Active learning in lectures and 'lectorials'

Search Professor Lesley Lluka’s works on UQ eSpace

90 works between 1991 and 2022
All (90) Journal Article (51) Conference Publication (38) Book (1)

81 - 90 of 90 works

1996

Journal Article

Evidence for uptake1-mediated efflux of catecholamines from pulmonary endothelial cells of perfused lungs of rats

Westwood N.N., Scarcella D.L. and Bryan-Lluka L.J. (1996). Evidence for uptake1-mediated efflux of catecholamines from pulmonary endothelial cells of perfused lungs of rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 353 (5), 528-535. doi: 10.1007/BF00169172

Evidence for uptake1-mediated efflux of catecholamines from pulmonary endothelial cells of perfused lungs of rats

1996

Journal Article

Amezinium and debrisoquine are substrates of uptake1 and potent inhibitors of monoamine oxidase in perfused lungs of rats

Bryan-Lluka L.J., Seers H. and Sharpe I. (1996). Amezinium and debrisoquine are substrates of uptake1 and potent inhibitors of monoamine oxidase in perfused lungs of rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 353 (5), 536-544. doi: 10.1007/BF00169173

Amezinium and debrisoquine are substrates of uptake1 and potent inhibitors of monoamine oxidase in perfused lungs of rats

1995

Journal Article

A kinetic investigation of the pulmonary metabolism of dopamine in rats shows marked differences compared with noradrenaline

Scarcella, D. L. and Bryan-Lluka, L. J. (1995). A kinetic investigation of the pulmonary metabolism of dopamine in rats shows marked differences compared with noradrenaline. Naunyn-Schmiedeberg's Archives of Pharmacology, 351 (5), 491-499. doi: 10.1007/BF00171040

A kinetic investigation of the pulmonary metabolism of dopamine in rats shows marked differences compared with noradrenaline

1995

Journal Article

Evidence for saturation of catechol-0-methyltransferase by low concentrations of noradrenaline in perfused lungs of rats

Bryan-Lluka, L. J. (1995). Evidence for saturation of catechol-0-methyltransferase by low concentrations of noradrenaline in perfused lungs of rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 351 (4), 408-416. doi: 10.1007/BF00169082

Evidence for saturation of catechol-0-methyltransferase by low concentrations of noradrenaline in perfused lungs of rats

1993

Journal Article

The effects of (-)-cromakalim and glibenclamide on uptake2 in guinea-pig trachealis muscle

Bryan-Lluka, L. J. and Vuocolo, H. E. (1993). The effects of (-)-cromakalim and glibenclamide on uptake2 in guinea-pig trachealis muscle. Naunyn-Schmiedeberg's Archives of Pharmacology, 348 (1), 65-69. doi: 10.1007/BF00168538

The effects of (-)-cromakalim and glibenclamide on uptake2 in guinea-pig trachealis muscle

1993

Journal Article

Types A and B monoamine oxidase contribute to the metabolism of norepinephrine in perfused lungs of rats

Westwood N.N. and Bryan-Lluka L.J. (1993). Types A and B monoamine oxidase contribute to the metabolism of norepinephrine in perfused lungs of rats. Journal of Pharmacology and Experimental Therapeutics, 267 (2), 815-821.

Types A and B monoamine oxidase contribute to the metabolism of norepinephrine in perfused lungs of rats

1992

Journal Article

Evidence from guinea-pig trachealis that Uptake2 of isoprenaline is enhanced by hyperpolarization of the smooth muscle

Bryan-Lluka, L. J. and Vuocolo, H. E. (1992). Evidence from guinea-pig trachealis that Uptake2 of isoprenaline is enhanced by hyperpolarization of the smooth muscle. Naunyn-Schmiedeberg's Archives of Pharmacology, 346 (4), 399-404. doi: 10.1007/BF00171081

Evidence from guinea-pig trachealis that Uptake2 of isoprenaline is enhanced by hyperpolarization of the smooth muscle

1992

Journal Article

Dopamine and adrenaline, but not isoprenaline, are substrates for uptake and metabolism in isolated perfused lungs of rats

Bryan-Lluka, L. J. and O'Donnell, S. R. (1992). Dopamine and adrenaline, but not isoprenaline, are substrates for uptake and metabolism in isolated perfused lungs of rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 346 (1), 20-26. doi: 10.1007/BF00167565

Dopamine and adrenaline, but not isoprenaline, are substrates for uptake and metabolism in isolated perfused lungs of rats

1991

Journal Article

Isolated perfused lungs of guinea-pig, in contrast with rat, lack an uptake process for noradrenaline

Bryan-Lluka L.J. and O'Donnell S.R. (1991). Isolated perfused lungs of guinea-pig, in contrast with rat, lack an uptake process for noradrenaline. Pulmonary Pharmacology, 4 (3), 146-150. doi: 10.1016/0952-0600(91)90004-M

Isolated perfused lungs of guinea-pig, in contrast with rat, lack an uptake process for noradrenaline

1991

Conference Publication

The effects of type 1 diabetes mellitus and of tobacco smoke on dissipation of catecholamines in pulmonary endothelial cells — a non-neuronal site of uptake1

Bryan-Lluka, L. J. and McKee, G. J. (1991). The effects of type 1 diabetes mellitus and of tobacco smoke on dissipation of catecholamines in pulmonary endothelial cells — a non-neuronal site of uptake1. Recent Advanced in Neuropharmacology, Würzburg, Germany, 22-24 March 1991. Vienna, Austria: Springer.

The effects of type 1 diabetes mellitus and of tobacco smoke on dissipation of catecholamines in pulmonary endothelial cells — a non-neuronal site of uptake1

Past funding

  • 2013 - 2016
    Development and implementation of MathBench for Australian universities to improve quantitative skills of science and mathematics students (OLT grant administered by Deakin University)
    Deakin University
    Open grant
  • 2009
    Liquid Scintillation Spectroscopy Facility
    UQ School/Centre Co-Funding
    Open grant
  • 2005 - 2007
    Determinants of Expression Assembly and Function of the Noradrenaline Transporter
    ARC Discovery Projects
    Open grant
  • 2003
    To Continue Established Collaboration With Professor Bonisch
    UQ Travel Grants Scheme
    Open grant
  • 2000 - 2002
    Molecular structure-function relationships of the moradrenaline transporter and drug action
    NHMRC Project Grant
    Open grant
  • 1998 - 2000
    Noradrenaline and Serotonin Transporter Regulation Implications for Therapy of Depression
    NHMRC Project Grant
    Open grant
  • 1996 - 1997
    Molecular identification and regulation of expression of monoamine transporters in pulmonary endothelial cells and other cell types - in collaboration with Professor H. Bonisch (Bonn, Germany) and Pro
    Quality Funds Round 3
    Open grant

Availability

Dr Lesley Lluka is:
Not available for supervision

Supervision history

Completed supervision

Enquiries

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