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Dr Run Zhang
Dr

Run Zhang

Email: 
Phone: 
+61 7 334 63806

Overview

Background

  • 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
  • 2022-now Senior Research Fellow, AIBN, The University of Queensland
  • 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
  • 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
  • 2016-2017 Research Associate, AIBN, The University of Queensland
  • 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
  • 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
  • July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China

Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.

Research Support: Since 2011, Dr Zhang has attracted 12 research grants (> 4 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.

Research Output: Dr Zhang has published more than 190 research papers since his first publication in 2010 (>100 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received ~10,000 citations with an H-index of 57. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.

Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier, 7/85 in Biochemical Research), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.

Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022 by Stanford/Elsevier World’s Top 2% Scientist Ranking, and top 0.5% of all scholars worldwide for excellence in research productivity, impact and quality by ScholarGPS Ranking (ranked #183 Globally in Biomedical Engineering). He has delivered 40+ invited presentations and keynotes.

Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.

Availability

Dr Run Zhang is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Engineering, Dalian University of Technology

Research interests

  • Responsive probes to detect and visualise highly reactive biomolecules

    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.

  • Functional nanomaterial for early diseases diagnosis and treatment

    engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.

  • Sensors for the detection of food quality & safety and environmental pollutants

    development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.

  • Bionanoprobes for deep tissue sensing and imaging

    fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.

  • Redox monitoring and regulation for diagnosis and treatment

    development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation

Works

Search Professor Run Zhang’s works on UQ eSpace

198 works between 2010 and 2025

141 - 160 of 198 works

2018

Journal Article

Bioanalytical methods for hypochlorous acid detection: recent advances and challenges

Zhang, Run, Song, Bo and Yuan, Jingli (2018). Bioanalytical methods for hypochlorous acid detection: recent advances and challenges. Trends in Analytical Chemistry, 99, 1-33. doi: 10.1016/j.trac.2017.11.015

Bioanalytical methods for hypochlorous acid detection: recent advances and challenges

2018

Journal Article

Recent progress in upconversion luminescence nanomaterials for biomedical applications

Duan, Chengchen, Liang, Liuen, Li, Li, Zhang, Run and Xu, Zhi Ping (2018). Recent progress in upconversion luminescence nanomaterials for biomedical applications. Journal of Materials Chemistry B, 6 (2), 192-209. doi: 10.1039/c7tb02527k

Recent progress in upconversion luminescence nanomaterials for biomedical applications

2018

Journal Article

X-ray fluorescence imaging of metals and metalloids in biological systems

Zhang, Run, Li, Li, Sultanbawa, Yasmina and Xu, Zhi Ping (2018). X-ray fluorescence imaging of metals and metalloids in biological systems. American Journal of Nuclear Medicine and Molecular Imaging, 8 (3), 169-188.

X-ray fluorescence imaging of metals and metalloids in biological systems

2018

Journal Article

A ruthenium(ii) complex–cyanine energy transfer scaffold based luminescence probe for ratiometric detection and imaging of mitochondrial peroxynitrite

Zhang, Wenzhu, Liu, Yi, Gao, Quankun, Liu, Chaolong, Song, Bo, Zhang, Run and Yuan, Jingli (2018). A ruthenium(ii) complex–cyanine energy transfer scaffold based luminescence probe for ratiometric detection and imaging of mitochondrial peroxynitrite. Chemical Communications, 54 (97), 13698-13701. doi: 10.1039/c8cc08061e

A ruthenium(ii) complex–cyanine energy transfer scaffold based luminescence probe for ratiometric detection and imaging of mitochondrial peroxynitrite

2017

Journal Article

Magnetic metal organic frameworks (MOFs) composite for removal of lead and malachite green in wastewater

Shi, Zhennan, Xu, Chen, Guan, Han, Li, Ling, Fan, Lu, Wang, Yingxi, Liu, Li, Meng, Qingtao and Zhang, Run (2017). Magnetic metal organic frameworks (MOFs) composite for removal of lead and malachite green in wastewater. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 539, 382-390. doi: 10.1016/j.colsurfa.2017.12.043

Magnetic metal organic frameworks (MOFs) composite for removal of lead and malachite green in wastewater

2017

Journal Article

Selective detection of inorganic phosphates in live cells based on a responsive fluorescence probe

Feng, Huan, Wang, Yue, Jia, Hongmin, Zhang, Run, Han, Qian, Meng, Qingtao and Zhang, Zhiqiang (2017). Selective detection of inorganic phosphates in live cells based on a responsive fluorescence probe. New Journal of Chemistry, 41 (18), 9623-9630. doi: 10.1039/c7nj01983a

Selective detection of inorganic phosphates in live cells based on a responsive fluorescence probe

2017

Journal Article

A gadolinium(III)-coumarin complex based MRI/Fluorescence bimodal probe for the detection of fluoride ion in aqueous. medium

Wang, Yue, Wang, Xueyi, Meng, Qingtao, Jia, Hongmin, Zhang, Run, Zhu, Peixun, Song, Renfeng, Feng, Huan and Zhang, Zhiqiang (2017). A gadolinium(III)-coumarin complex based MRI/Fluorescence bimodal probe for the detection of fluoride ion in aqueous. medium. Tetrahedron, 73 (38), 5700-5705. doi: 10.1016/j.tet.2017.08.007

A gadolinium(III)-coumarin complex based MRI/Fluorescence bimodal probe for the detection of fluoride ion in aqueous. medium

2017

Journal Article

Mannose-conjugated layered double hydroxide nanocomposite for targeted siRNA delivery to enhance cancer therapy

Li, Li, Zhang, Run, Gu, Wenyi and Ping, Zhi (2017). Mannose-conjugated layered double hydroxide nanocomposite for targeted siRNA delivery to enhance cancer therapy. Nanomedicine: Nanotechnology, Biology and Medicine, 14 (7), 2355-2364. doi: 10.1016/j.nano.2017.06.006

Mannose-conjugated layered double hydroxide nanocomposite for targeted siRNA delivery to enhance cancer therapy

2017

Journal Article

A mitochondria-targeted ratiometric probe for the fluorescent and colorimetric detection of SO2 derivatives in live cells

Wang, Yongfei, Meng, Qingtao, Zhang, Run, Jia, Hongmin, Wang, Cuiping and Zhang, Zhiqiang (2017). A mitochondria-targeted ratiometric probe for the fluorescent and colorimetric detection of SO2 derivatives in live cells. Journal of Luminescence, 192, 297-302. doi: 10.1016/j.jlumin.2017.06.033

A mitochondria-targeted ratiometric probe for the fluorescent and colorimetric detection of SO2 derivatives in live cells

2017

Journal Article

Development of a novel lysosome-targeted ruthenium(II) complex for phosphorescence/ time-gated luminescence assay of biothiols

Gao, Quankun, Zhang, Wenzhu, Song, Bo, Zhang, Run, Guo, Weihua and Yuan, Jingli (2017). Development of a novel lysosome-targeted ruthenium(II) complex for phosphorescence/ time-gated luminescence assay of biothiols. Analytical Chemistry, 89 (8), 4517-4524. doi: 10.1021/acs.analchem.6b04925

Development of a novel lysosome-targeted ruthenium(II) complex for phosphorescence/ time-gated luminescence assay of biothiols

2017

Journal Article

A ratiometric fluorescence probe for imaging sulfur dioxide derivatives in the mitochondria of living cells

Wang, Yongfei, Meng, Qingtao, Zhang, Run, Jia, Hongmin, Zhang, Xuehu and Zhang, Zhiqiang (2017). A ratiometric fluorescence probe for imaging sulfur dioxide derivatives in the mitochondria of living cells. Organic and Biomolecular Chemistry, 15 (13), 2734-2739. doi: 10.1039/c6ob02779b

A ratiometric fluorescence probe for imaging sulfur dioxide derivatives in the mitochondria of living cells

2017

Journal Article

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374. doi: 10.1038/srep45374

Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury

2017

Journal Article

Deep-penetrating photodynamic therapy with KillerRed mediated by upconversion nanoparticles

Liang, Liuen, Lu, Yiqing, Zhang, Run, Care, Andrew, Ortega, Tiago A., Deyev, Sergey M., Qian, Yi and Zvyagin, Andrei V. (2017). Deep-penetrating photodynamic therapy with KillerRed mediated by upconversion nanoparticles. Acta Biomaterialia, 51, 461-470. doi: 10.1016/j.actbio.2017.01.004

Deep-penetrating photodynamic therapy with KillerRed mediated by upconversion nanoparticles

2017

Journal Article

Red-emitting ruthenium(II) and iridium(III) complexes as phosphorescent probes for methylglyoxal in vitro and in vivo

Zhang, Wenzhu, Zhang, Feiyue, Wang, Yong-Lei, Song, Bo, Zhang, Run and Yuan, Jingli (2017). Red-emitting ruthenium(II) and iridium(III) complexes as phosphorescent probes for methylglyoxal in vitro and in vivo. Inorganic Chemistry, 56 (3), 1309-1318. doi: 10.1021/acs.inorgchem.6b02443

Red-emitting ruthenium(II) and iridium(III) complexes as phosphorescent probes for methylglyoxal in vitro and in vivo

2017

Journal Article

A unique iridium(III) complex-based chemosensor for multi-signal detection and multi-channel imaging of hypochlorous acid in liver injury

Zhang, Feiyue, Liang, Xiaowen, Zhang, Wenzhu, Wang, Yong-Lei, Wang, Haolu, Mohammed, Yousuf H., Song, Bo, Zhang, Run and Yuan, Jingli (2017). A unique iridium(III) complex-based chemosensor for multi-signal detection and multi-channel imaging of hypochlorous acid in liver injury. Biosensors and Bioelectronics, 87, 1005-1011. doi: 10.1016/j.bios.2016.09.067

A unique iridium(III) complex-based chemosensor for multi-signal detection and multi-channel imaging of hypochlorous acid in liver injury

2017

Journal Article

Functionalization of mixed ligand metal-organic frameworks as the transport vehicles for drugs

Sun, Keke, Li, Ling, Yu, XiaoLan, Liu, Li, Meng, Qingtao, Wang, Fei and Zhang, Run (2017). Functionalization of mixed ligand metal-organic frameworks as the transport vehicles for drugs. Journal of Colloid and Interface Science, 486, 128-135. doi: 10.1016/j.jcis.2016.09.068

Functionalization of mixed ligand metal-organic frameworks as the transport vehicles for drugs

2017

Book Chapter

Development and Applications of Upconversion Nanoparticle in Biosensing

Liang, Liuen, Zvyagin, Andrei V. and Zhang, Run (2017). Development and Applications of Upconversion Nanoparticle in Biosensing. Advances in Biosensors: Reviews. (pp. 49-79) edited by Sergey Y. Yurish. Barcelona, Spain: International Frequency Sensor Association (IFSA).

Development and Applications of Upconversion Nanoparticle in Biosensing

2017

Journal Article

Renewable metal-organic-frameworks-coated 3D printing film for removal of malachite green

Shi, Zhennan, Xu, Chen, Chen, Fei, Wang, Yingxi, Li, Ling, Meng, Qingtao and Zhang, Run (2017). Renewable metal-organic-frameworks-coated 3D printing film for removal of malachite green. Rsc Advances, 7 (79), 49947-49952. doi: 10.1039/c7ra10912a

Renewable metal-organic-frameworks-coated 3D printing film for removal of malachite green

2017

Journal Article

Development and Applications of Upconversion Nanoparticle in Biosensing

Liang, Liuen, Zvyagin, Andrei V. and Zhang, Run (2017). Development and Applications of Upconversion Nanoparticle in Biosensing. Advances in Biosensors: Reviews, Vol 1, 1, 49-79.

Development and Applications of Upconversion Nanoparticle in Biosensing

2017

Conference Publication

In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe

Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2242978

In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe

Funding

Current funding

  • 2020 - 2025
    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2018
    Paper-based sensing devices for quick and effective monitoring of red meat quality
    UQ Early Career Researcher
    Open grant
  • 2017 - 2019
    X-ray Induced Photoacoustic Nanoprobe: Break Depth Dependency of Bioimaging
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2017 - 2019
    Visualisation and early prediction of ROS-mediated treatment response in liver cancer by a novel nanoplatform
    NHMRC Project Grant
    Open grant

Supervision

Availability

Dr Run Zhang is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Responsive molecules and nanomaterials for bisoensing and bioimaging

  • Sensors for environmental pollutants and food quality & safety

  • Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy

Supervision history

Current supervision

  • Doctor Philosophy

    Development of responsive nanoprobe for enzyme analysis in inflammation

    Principal Advisor

  • Doctor Philosophy

    Responsive nanoprobe for redox biomolecules quantification

    Principal Advisor

  • Doctor Philosophy

    Responsive probe for time-gated luminescence bioassay and imaging

    Principal Advisor

    Other advisors: Dr Jiaxi Yong

  • Doctor Philosophy

    Functional piezoelectric scaffolds for bone tissue regeneration

    Principal Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Activatable nanomaterials for cancer treatment

    Principal Advisor

    Other advisors: Dr Ruirui Qiao

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    New Strategies in Targeted Proteolysis with Nanoparticle-Mediated mRNA Delivery

    Associate Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology

    Associate Advisor

    Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa

  • Doctor Philosophy

    The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Optimization and Characterization of Seaweed Bioactive Materials for Encapsulation and Valorization of Seaweed based products

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa, Dr Dharini Sivakumar

  • Doctor Philosophy

    Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers

    Associate Advisor

    Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa

Completed supervision

Media

Enquiries

Contact Dr Run Zhang directly for media enquiries about:

  • Biosensing and imaging
  • Cancer
  • Environmental pollution
  • Food safety
  • Inflammation
  • Optical probe
  • Redox biomolecules
  • Sensor
  • Stress resilience
  • Theranostic nanomaterials

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