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Dr Run Zhang
Dr

Run Zhang

Email: 
Phone: 
+61 7 334 63806

Overview

Background

  • 2023-now Joint Senior Research Fellow, Centre for Nutrition and Food Sciences, The Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI)
  • 2022-now Senior Research Fellow, AIBN, The University of Queensland
  • 2020-now NHMRC Emerging Leadership Fellow, AIBN, The University of Queensland
  • 2017-2019 ARC DECRA Fellow, AIBN, The University of Queensland
  • 2016-2017 Research Associate, AIBN, The University of Queensland
  • 2013-2015 Macquarie University Research Fellow (MQRF), Department of Chemistry and Biomolecular Science (CBMS), Macquarie University
  • 2012-2013 Postdoc Research Fellow, Department of Physics and Astronomy, Macquarie University
  • July 2012 PhD, Analytical Chemistry, Dalian University of Technology (DLUT), China

Research Team: Dr Zhang is now leading more than 15 researchers, working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food/agricultural/environmental applications. He has collaborations with scientist in Chemistry, Materials Science, Molecular Biology and Biotechnology, Food and Agriculture Science, and Biophotonics from Australia, US, UK, Sweden, India, Russia and China.

Research Support: Since 2011, Dr Zhang has attracted 11 research grants (> 3 million) as chief investigator (lead CI and/or co-CI). These grants include 3 Fellowship (NHMRC Emerging Leadership, ARC DECRA and MQRF to develop responsive probes for redox biomarkers detection within body), 1 NHMRC Project grant in redox quantification in liver cancer chemotherapy, 1 UQ ECR grant, 1 NSFC grant, and another 3 grants from universities.

Research Output: Dr Zhang has published more than 180 research papers since his first publication in 2010 (>95 papers published as first and/or corresponding author), and 1 patent. He frequently publishes in a number of premier journals, such as Nature Photonics, Nature Plants, Journal of the American Chemical Society (JACS), Angewandte Chemie, Analytical Chemistry, Chemical Society Reviews, and Accounts of Chemical Research. These publications have received >9,000 citations with an H-index of 55. He has 8 Highly Cited Papers (7 in the ESI field of Chemistry-Analytical) and 3 Hot Articles.

Service: Dr Zhang is an Editor of TrAC Trends in Analytical Chemistry (Elsevier, 1/106 in Analytical Chemistry) and Methods (Elsevier, 7/85 in Biochemical Research), and Editorial Board Member of several international high impact journals, such as Chemistry-An Asian Journal (Wiley), Aggregate (Wiley), Journal of Pharmaceutical Analysis (Elsevier), Green Analytical Chemistry (Elsevier). He is a referee of ~80 international journals (2nd most contributions of all UQ researchers, with >20 awards from RSC and Elsevier journals), and grant assessor for more than 10 country and regions, such as Australia, UK, Europe, Netherland, New Zealand.

Award: Dr Zhang's national and international standing in the fields of chemistry (analytical and inorganic) and functional nanomaterials is evidenced by the awards of ACS Rising Star in Measurement Science, NJC Emerging Investigator, Biosensors Young Investigator Award, IAAM Scientist Medal, Vebleo Fellow, IAAM Fellow, ARC DECRA, NHMRC EL Fellow, MQRF, and more than 20 TOP Outstanding Reviewer awards from RSC and Elsevier. He has been a World's Top 2% Scientist in Chemistry (Analytical) and Nanoscience & Nanotechnology since 2022 by Stanford/Elsevier World’s Top 2% Scientist Ranking, and top 0.5% of all scholars worldwide for excellence in research productivity, impact and quality by ScholarGPS Ranking (ranked #183 Globally in Biomedical Engineering). He has delivered about 40 invited presentations and keynotes.

Teaching and Supervision: Dr Zhang has a strong commitment to training students. His students have received several awards, such as 4 "Dean’s Commendation for Outstanding Academic Performance", 1 "Dean’s Award for Excellence in Higher Degree Research", 1 "Dean's Award for Outstanding HDR Theses", ANFF-Q students award, 3MT Runner-UP and People's Choice. He has supervised 6 PhD and >20 Masters to completion. He is now co-coordinating and lecturing the MSE PP ENGY7112/7115/7114/7215 in School of Chem. Eng., EAIT. His teaching contributions in Faculty of Science, UQ are recognised by two nominations of "Dean’s Commendation for Excellent Teaching Awards" in semesters 1 and 2 in 2022.

Availability

Dr Run Zhang is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Engineering, Dalian University of Technology

Research interests

  • Responsive probes to detect and visualise highly reactive biomolecules

    design and synthesis of organic/organometallic complexes (including Ru(II) and Ir(III) complexes and lanthanide chelate) for sensing of bioactive ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), redox biomolecules, gasotransmitters, amino acid, and proteins in various diseases, such as cancer, cardiovascular, and inflammatory diseases.

  • Functional nanomaterial for early diseases diagnosis and treatment

    engineering of functional nanomaterials for disease detection and treatment through monitoring and regulation of redox state, including photodynamic therapy (PDT), photothermal therapy (PTT), and sonodynamic therapy (SDT) for diseases deeply seated in body.

  • Sensors for the detection of food quality & safety and environmental pollutants

    development of ultra-sensitive sensors for the detection of food additives, antibiotics, pesticides, spoilage, heavy metals, toxic anions and gases (greenhouse gases and VOCs), etc.

  • Bionanoprobes for deep tissue sensing and imaging

    fabrication of responsive nanomaterials for sensing and imaging of biomarkers located deeply inside the body. The probes allow the monitoring of specific disease-related biomarkers through optical, acoustic, and magnetic resonance spectroscopy.

  • Redox monitoring and regulation for diagnosis and treatment

    development of novel luminescent probes with long emission lifetime to eliminate autofluorescence, allowing background-free quantification and bioimaging of redox species in situ development of responsive nanomaterials for treatment through quantitative redox regulation

Works

Search Professor Run Zhang’s works on UQ eSpace

190 works between 2010 and 2025

161 - 180 of 190 works

2016

Journal Article

Synthesis and application of an aldazine-based fluorescence chemosensor for the sequential detection of Cu2+ and biological thiols in aqueous solution and living cells

Jia, Hongmin, Yang, Ming, Meng, Qingtao, He, Guangjie, Wang, Yue, Hu, Zhizhi, Zhang, Run and Zhang, Zhiqiang (2016). Synthesis and application of an aldazine-based fluorescence chemosensor for the sequential detection of Cu2+ and biological thiols in aqueous solution and living cells. Sensors, 16 (1) 79, 79. doi: 10.3390/s16010079

Synthesis and application of an aldazine-based fluorescence chemosensor for the sequential detection of Cu2+ and biological thiols in aqueous solution and living cells

2016

Journal Article

Controllable preparation and drug loading properties of core–shell microspheres Fe3O4@MOFs/GO

Li, Ling, Wu, Ya Q., Sun, Ke K., Zhang, Run, Fan, Lu, Liang, Ke K. and Mao, Le B. (2016). Controllable preparation and drug loading properties of core–shell microspheres Fe3O4@MOFs/GO. Materials Letters, 162, 207-210. doi: 10.1016/j.matlet.2015.09.096

Controllable preparation and drug loading properties of core–shell microspheres Fe3O4@MOFs/GO

2016

Journal Article

Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney

Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016). Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 (1), 387-395. doi: 10.1021/acsnano.5b05066

Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney

2016

Conference Publication

Upconversion nanocrystals doped glass: a new paradigm for integrated optical glass

Zhao, Jiangbo, Zheng, Xianlin, Schartner, Erik P., Ionescu, Paul, Zhang, Run, Nguyen, Tich-Lam, Jin, Dayong and Ebendorff-Heidepriem, Heike (2016). Upconversion nanocrystals doped glass: a new paradigm for integrated optical glass. Photonics and Fiber Technology , Sydney, Australia, 5–8 September 2016. Washington, DC, United States: OSA. doi: 10.1364/acoft.2016.am5c.7

Upconversion nanocrystals doped glass: a new paradigm for integrated optical glass

2015

Journal Article

A highly selective and sensitive ON-OFF-ON fluorescence chemosensor for cysteine detection in endoplasmic reticulum

Meng, Qingtao, Jia, Hongmin, Succar, Peter, Zhao, Liang, Zhang, Run, Duan, Chunying and Zhang, Zhigiang (2015). A highly selective and sensitive ON-OFF-ON fluorescence chemosensor for cysteine detection in endoplasmic reticulum. Biosensors and Bioelectronics, 74, 461-468. doi: 10.1016/j.bios.2015.06.077

A highly selective and sensitive ON-OFF-ON fluorescence chemosensor for cysteine detection in endoplasmic reticulum

2015

Journal Article

A ruthenium(II) complex-based lysosome-targetable multisignal chemosensor for in vivo detection of hypochlorous acid

Cao, Liyan, Zhang, Run, Zhang, Wenzhu, Du, Zhongbo, Liu, Chunjun, Ye, Zhiqiang, Song, Bo and Yuan, Jingli (2015). A ruthenium(II) complex-based lysosome-targetable multisignal chemosensor for in vivo detection of hypochlorous acid. Biomaterials, 68, 21-31. doi: 10.1016/j.biomaterials.2015.07.052

A ruthenium(II) complex-based lysosome-targetable multisignal chemosensor for in vivo detection of hypochlorous acid

2015

Journal Article

Fluorescence detection of Fe3+ ions in aqueous solution and living cells based on a high selectivity and sensitivity chemosensor

Jia, Hongmin, Gao, Xue, Shi, Yu, Sayyadi, Nima, Zhang, Zhiqiang, Zhao, Qi, Meng, Qingtao and Zhang, Run (2015). Fluorescence detection of Fe3+ ions in aqueous solution and living cells based on a high selectivity and sensitivity chemosensor. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 149, 674-681. doi: 10.1016/j.saa.2015.04.111

Fluorescence detection of Fe3+ ions in aqueous solution and living cells based on a high selectivity and sensitivity chemosensor

2015

Journal Article

A reversible fluorescence chemosensor for sequentially quantitative monitoring copper and sulfide in living cells

Meng, Qingtao, Zhang, Run, Jia, Hongmin, Gao, Xue, Wang, Cuiping, Shi, Yu, Everest-Dass, Arun V. and Zhang, Zhiqiang (2015). A reversible fluorescence chemosensor for sequentially quantitative monitoring copper and sulfide in living cells. Talanta, 143 15572, 294-301. doi: 10.1016/j.talanta.2015.04.072

A reversible fluorescence chemosensor for sequentially quantitative monitoring copper and sulfide in living cells

2015

Journal Article

NBD-based fluorescent chemosensor for the selective quantification of copper and sulfide in an aqueous solution and living cells

Meng, Qingtao, Shi, Yu, Wang, Cuiping, Jia, Hongmin, Gao, Xue, Zhang, Run, Wang, Yongfei and Zhang, Zhiqiang (2015). NBD-based fluorescent chemosensor for the selective quantification of copper and sulfide in an aqueous solution and living cells. Organic & Biomolecular Chemistry, 13 (10), 2918-2926. doi: 10.1039/c4ob02178a

NBD-based fluorescent chemosensor for the selective quantification of copper and sulfide in an aqueous solution and living cells

2015

Journal Article

A new fluorescent chemosensor for highly selective and sensitive detection of inorganic phosphate (Pi) in aqueous solution and living cells

Meng, Qingtao, Wang, Yue, Yang, Ming, Zhang, Run, Wang, Renjie and Zhang, Zhiqiang (2015). A new fluorescent chemosensor for highly selective and sensitive detection of inorganic phosphate (Pi) in aqueous solution and living cells. RSC Advances, 5 (66), 53189-53197. doi: 10.1039/c5ra08712k

A new fluorescent chemosensor for highly selective and sensitive detection of inorganic phosphate (Pi) in aqueous solution and living cells

2015

Journal Article

Reversible and Selective Fluorescence Detection of Histidine Using a Naphthalimide-Based Chemosensing Ensemble

Meng, Qingtao, Jia, Hongmin, Gao, Xue, Wang, Yue, Zhang, Run, Wang, Renjie and Zhang, Zhiqiang (2015). Reversible and Selective Fluorescence Detection of Histidine Using a Naphthalimide-Based Chemosensing Ensemble. Chemistry - An Asian Journal, 10 (11), 2411-2418. doi: 10.1002/asia.201500690

Reversible and Selective Fluorescence Detection of Histidine Using a Naphthalimide-Based Chemosensing Ensemble

2014

Journal Article

Development of a functional ruthenium(II) complex for probing hypochlorous acid in living cells

Ye, Zhiqiang, Zhang, Run, Song, Bo, Dai, Zhichao, Jin, Dayong, Goldys, Ewa M. and Yuan, Jingli (2014). Development of a functional ruthenium(II) complex for probing hypochlorous acid in living cells. Dalton Transactions, 43 (22), 8414-8420. doi: 10.1039/c4dt00179f

Development of a functional ruthenium(II) complex for probing hypochlorous acid in living cells

2014

Conference Publication

Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex

Zhang, Peng, Ruan, Shuai, Zhang, Run, Pullen, Benjamin, Zhang, Xiaozhou, Purdey, Malcolm Stuart, Ebendorff-Heidepriem, Heike, Abell, Andrew, Ding, Liyun, Tang, Ming and Ruan, Yinlan (2014). Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex. Asia-Pacific Optical Sensors Conference, APOS 2016, Shanghai China, 11-14 October 2016. Washington, DC United States: OSA - The Optical Society. doi: 10.1364/APOS.2016.W3A.5

Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex

2014

Journal Article

Tunable lifetime multiplexing using luminescent nanocrystals

Lu, Yiqing, Zhao, Jiangbo, Zhang, Run, Liu, Yujia, Liu, Deming, Goldys, Ewa M., Yang, Xusan, Xi, Peng, Sunna, Anwar, Lu, Jie, Shi, Yu, Leif, Robert C., Huo, Yujing, Shen, Jian, Piper, James A., Robinson, J. Paul and Jin, Dayong (2014). Tunable lifetime multiplexing using luminescent nanocrystals. Nature Photonics, 8 (1), 33-37. doi: 10.1038/NPHOTON.2013.322

Tunable lifetime multiplexing using luminescent nanocrystals

2013

Journal Article

Highly sensitive and selective phosphorescent chemosensors for hypochlorous acid based on ruthenium(II) complexes

Zhang, Run, Song, Bo, Dai, Zhichao, Ye, Zhiqiang, Xiao, Yunna, Liu, Yan and Yuan, Jingli (2013). Highly sensitive and selective phosphorescent chemosensors for hypochlorous acid based on ruthenium(II) complexes. Biosensors and Bioelectronics, 50, 1-7. doi: 10.1016/j.bios.2013.06.005

Highly sensitive and selective phosphorescent chemosensors for hypochlorous acid based on ruthenium(II) complexes

2013

Journal Article

A lanthanide complex-based ratiometric luminescence probe for time-gated luminescence detection of intracellular thiols

Dai, Zhichao, Tian, Lu, Ye, Zhiqiang, Song, Bo, Zhang, Run and Yuan, Jingli (2013). A lanthanide complex-based ratiometric luminescence probe for time-gated luminescence detection of intracellular thiols. Analytical Chemistry, 85 (23), 11658-11664. doi: 10.1021/ac403370g

A lanthanide complex-based ratiometric luminescence probe for time-gated luminescence detection of intracellular thiols

2013

Journal Article

Development and application of a ruthenium(II) complex-based photoluminescent and electrochemiluminescent dual-signaling probe for nitric oxide

Zhang, Wenzhu, Zhang, Jingmei, Zhang, Hailei, Cao, Liyan, Zhang, Run, Ye, Zhiqiang and Yuan, Jingli (2013). Development and application of a ruthenium(II) complex-based photoluminescent and electrochemiluminescent dual-signaling probe for nitric oxide. Talanta, 116, 354-360. doi: 10.1016/j.talanta.2013.05.064

Development and application of a ruthenium(II) complex-based photoluminescent and electrochemiluminescent dual-signaling probe for nitric oxide

2013

Journal Article

Design and synthesis of a ruthenium(II) complex-based luminescent probe for highly selective and sensitive luminescence detection of nitric oxide

Yu, Xiaojing, Zhang, Run, Ye, Zhiqiang, Song, Bo and Yuan, Jingli (2013). Design and synthesis of a ruthenium(II) complex-based luminescent probe for highly selective and sensitive luminescence detection of nitric oxide. Journal of Fluorescence, 23 (6), 1113-1120. doi: 10.1007/s10895-013-1240-8

Design and synthesis of a ruthenium(II) complex-based luminescent probe for highly selective and sensitive luminescence detection of nitric oxide

2013

Journal Article

Development of a ruthenium(II) complex-based luminescent probe for hypochlorous acid in living cells

Zhang, Run, Ye, Zhiqiang, Song, Bo, Dai, Zhichao, An, Xin and Yuan, Jingli (2013). Development of a ruthenium(II) complex-based luminescent probe for hypochlorous acid in living cells. Inorganic Chemistry, 52 (18), 10325-10331. doi: 10.1021/ic400767u

Development of a ruthenium(II) complex-based luminescent probe for hypochlorous acid in living cells

2013

Journal Article

Development of singlet oxygen-responsive phosphorescent ruthenium(ii) complexes

Ye, Zhiqiang, Song, Bo, Yin, Yuejiao, Zhang, Run and Yuan, Jingli (2013). Development of singlet oxygen-responsive phosphorescent ruthenium(ii) complexes. Dalton Transactions, 42 (40), 14380-14383. doi: 10.1039/c3dt52020j

Development of singlet oxygen-responsive phosphorescent ruthenium(ii) complexes

Funding

Current funding

  • 2020 - 2025
    Monitoring inflammation through quantitation of redox-mediated macrophage polarisation
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2018
    Paper-based sensing devices for quick and effective monitoring of red meat quality
    UQ Early Career Researcher
    Open grant
  • 2017 - 2019
    X-ray Induced Photoacoustic Nanoprobe: Break Depth Dependency of Bioimaging
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2017 - 2019
    Visualisation and early prediction of ROS-mediated treatment response in liver cancer by a novel nanoplatform
    NHMRC Project Grant
    Open grant

Supervision

Availability

Dr Run Zhang is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Responsive molecules and nanomaterials for bisoensing and bioimaging

  • Sensors for environmental pollutants and food quality & safety

  • Theranostic nanomaterials: especially the optical nanomaterials for diagnosis and therapy

Supervision history

Current supervision

  • Doctor Philosophy

    Responsive probe for time-gated luminescence bioassay and imaging

    Principal Advisor

    Other advisors: Dr Jiaxi Yong

  • Doctor Philosophy

    Development of responsive nanoprobe for enzyme analysis in inflammation

    Principal Advisor

  • Doctor Philosophy

    Sensitive Detection of Antibiotics with Nanoprobes

    Principal Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Responsive nanoprobe for redox biomolecules quantification

    Principal Advisor

  • Doctor Philosophy

    Functional piezoelectric scaffolds for bone tissue regeneration

    Principal Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Activatable nanomaterials for cancer treatment

    Principal Advisor

    Other advisors: Dr Ruirui Qiao

  • Doctor Philosophy

    Upconversion-encoded microspheres for glucocorticoids detection as food hazards or health markers

    Associate Advisor

    Other advisors: Dr Kayvan Etebari, Dr Zeinab Khalil, Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Thermo-triggered Release of Drug/Gene Carrier System by Lipid-Encapsulated Gold Nanoparticles for Tumour Therapy

    Associate Advisor

    Other advisors: Dr Li Li

  • Doctor Philosophy

    Optimization and Characterization of Seaweed Bioactive Materials for Encapsulation and Valorization of Seaweed based products

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa, Dr Dharini Sivakumar

  • Doctor Philosophy

    The efficacy of nanoencapsulation as a delivery system of Terminalia ferdinandiana extract for periodontal disease therapy

    Associate Advisor

    Other advisors: Professor Yasmina Sultanbawa

  • Doctor Philosophy

    Improving the Shelf-life of Salmon Fillets Using an Advanced Nanoencapsulation Technology

    Associate Advisor

    Other advisors: Dr Dharini Sivakumar, Professor Yasmina Sultanbawa

Completed supervision

Media

Enquiries

Contact Dr Run Zhang directly for media enquiries about:

  • Biosensing and imaging
  • Cancer
  • Environmental pollution
  • Food safety
  • Inflammation
  • Optical probe
  • Redox biomolecules
  • Sensor
  • Stress resilience
  • Theranostic nanomaterials

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