Dr Angeline Chan
Dr

Angeline Chan

Email: 
Phone: 
+61 7 344 36299

Availability

Dr Angeline Chan is:
Available for supervision

Fields of research

Analytical biochemistry Analytical chemistry Analytical spectrometry Basic pharmacology Bioassays Biochemistry and cell biology Biological Sciences Biomedical and Clinical Sciences Cardiovascular medicine and haematology Cell metabolism Chemical Sciences Health Sciences Medical biochemistry - proteins and peptides (incl. medical proteomics) Medical biochemistry and metabolomics Medicinal and biomolecular chemistry Pharmacology and pharmaceutical sciences Proteins and peptides Proteomics and intermolecular interactions (excl. medical proteomics) Receptors and membrane biology

Qualifications

  • Bachelor, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Angeline Chan’s works on UQ eSpace

58 works between 2009 and 2025
All (58) Journal Article (54) Other Outputs (1) Conference Publication (3)

21 - 40 of 58 works

2022

Journal Article

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

Xie, Jing, Robinson, Samuel D., Gilding, Edward K., Jami, Sina, Deuis, Jennifer R., Rehm, Fabian B.H., Yap, Kuok, Ragnarsson, Lotten, Chan, Lai Yue, Hamilton, Brett R., Harvey, Peta J., Craik, David J., Vetter, Irina and Durek, Thomas (2022). Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox. Journal of Biological Chemistry, 298 (8) 102218, 1-12. doi: 10.1016/j.jbc.2022.102218

Neurotoxic and cytotoxic peptides underlie the painful stings of the tree nettle Urtica ferox

2022

Journal Article

Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides

Dang, Tien T., Harvey, Peta J., Chan, Lai Yue, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2022). Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides. Peptide Science, 114 (6) e24284. doi: 10.1002/pep2.24284

Mutagenesis of cyclotide Cter 27 exemplifies a robust folding strategy for bracelet cyclotides

2022

Journal Article

Antinociceptive peptides from venomous arthropods

Muller, Jessica A. I., Chan, Lai Y., Toffoli-Kadri, Monica C., Mortari, Marcia R., Craik, David J. and Koehbach, Johannes (2022). Antinociceptive peptides from venomous arthropods. Toxin Reviews, 42 (1), 1-20. doi: 10.1080/15569543.2022.2065510

Antinociceptive peptides from venomous arthropods

2022

Journal Article

Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming

Doffek, Benjamin, Huang, Yvonne, Huang, Yen-Hua, Chan, Lai Yue, Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2022). Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming. Phytochemistry, 195 113053, 1-10. doi: 10.1016/j.phytochem.2021.113053

Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming

2021

Conference Publication

An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

Silva Cardoso, Marlon Henrique E., Chan, Lai Yue, Candido, Elizabete De Souza, Torres, Marcelo D. T., Oshiro, Karen G. N., Silva, Itala C., Goncalves, S., Buccini, Danieli Fernanda, Lu, Timothy K., Santos, Nuno C., De la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octavio L. (2021). An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. 20th IUPAB International Congress, 45th SBBf Congress and 50th Annual Meeting of SBBq, Online, 4-8 October 2021. London, United Kingdom: Springer.

An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

2021

Journal Article

Antimicrobial and anticancer properties of synthetic peptides derived from the wasp Parachartergus fraternus

Muller, Jessica A. I., Lawrence, Nicole, Chan, Lai Yue, Harvey, Peta J., Elliott, Alysha G., Blaskovich, Mark A. T., Gonçalves, Jacqueline C., Galante, Priscilla, Mortari, Marcia R., Toffoli-Kadri, Mônica C., Koehbach, Johannes and Craik, David (2021). Antimicrobial and anticancer properties of synthetic peptides derived from the wasp Parachartergus fraternus. Chembiochem , 22 (8) cbic.202000716, 1415-1423. doi: 10.1002/cbic.202000716

Antimicrobial and anticancer properties of synthetic peptides derived from the wasp Parachartergus fraternus

2021

Journal Article

Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity

Nadal-Bufi, Ferran, Mason, Jody M., Chan, Lai Yue, Craik, David J., Kaas, Quentin and Troeira Henriques, Sónia (2021). Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of Medicinal Chemistry, 64 (7) acs.jmedchem.0c01898, 3767-3779. doi: 10.1021/acs.jmedchem.0c01898

Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity

2021

Journal Article

In planta discovery and chemical synthesis of bracelet cystine knot peptides from Rinorea bengalensis

Dang, Tien T., Chan, Lai Y., Tombling, Benjamin J., Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2021). In planta discovery and chemical synthesis of bracelet cystine knot peptides from Rinorea bengalensis. Journal of Natural Products, 84 (2), 395-407. doi: 10.1021/acs.jnatprod.0c01065

In planta discovery and chemical synthesis of bracelet cystine knot peptides from Rinorea bengalensis

2021

Journal Article

Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytes

Pinto, Meri Emili F., Chan, Lai Yue, Koehbach, Johannes, Devi, Seema, Gründemann, Carsten, Gruber, Christian W., Gomes, Mario, Bolzani, Vanderlan S., Cilli, Eduardo Maffud and Craik, David J. (2021). Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytes. Journal of Natural Products, 84 (1) acs.jnatprod.0c01069, 81-90. doi: 10.1021/acs.jnatprod.0c01069

Cyclotides from Brazilian Palicourea sessilis and their effects on human lymphocytes

2021

Journal Article

Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells

Benfield, Aurélie H., Defaus, Sira, Lawrence, Nicole, Chaousis, Stephanie, Condon, Nicholas, Cheneval, Olivier, Huang, Yen-Hua, Chan, Lai Yue, Andreu, David, Craik, David J. and Henriques, Sónia Troeira (2021). Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells. Biochimica et Biophysica Acta - Biomembranes, 1863 (1) 183480, 183480. doi: 10.1016/j.bbamem.2020.183480

Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells

2020

Journal Article

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L. and Craik, David J. (2020). Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes. Peptide Science, 113 (4) e24209. doi: 10.1002/pep2.24209

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

2020

Journal Article

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

Yap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h

An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides

2020

Journal Article

Exploring the sequence diversity of cyclotides from Vietnamese Viola species

Dang, Tien T., Chan, Lai Y., Huang, Yen-Hua, Nguyen, Linh T. T., Kaas, Quentin, Huynh, Tien and Craik, David J. (2020). Exploring the sequence diversity of cyclotides from Vietnamese Viola species. Journal of Natural Products, 83 (6) acs.jnatprod.9b01218, 1817-1828. doi: 10.1021/acs.jnatprod.9b01218

Exploring the sequence diversity of cyclotides from Vietnamese Viola species

2020

Journal Article

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

Du, Qingdan, Chan, Lai Y., Gilding, Edward K., Henriques, Sónia Troeira, Condon, Nicholas D., Ravipati, Anjaneya S., Kaas, Quentin, Huang, Yen-Hua and Craik, David J. (2020). Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus. Journal of Biological Chemistry, 295 (32), jbc.RA120.012627-10925. doi: 10.1074/jbc.ra120.012627

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

2019

Journal Article

Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties

Oshiro, Karen G. N., Cândido, Elizabete S., Chan, Lai Y., Torres, Marcelo D. T., Monges, Bruna E. D., Rodrigues, Silvia G., Porto, William F., Ribeiro, Suzana M., Henriques, Sónia T., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2019). Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties. Journal of Medicinal Chemistry, 62 (17), 8140-8151. doi: 10.1021/acs.jmedchem.9b00915

Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties

2019

Journal Article

Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential

Cândido, Elizabete S., Cardoso, Marlon H., Chan, Lai Y., Torres, Marcelo D. T., Oshiro, Karen G. N., Porto, William F., Ribeiro, Suzana M., Haney, Evan F., Hancock, Robert E. W., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2019). Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential. ACS Infectious Diseases, 5 (7) acsinfecdis.9b00073, 1081-1086. doi: 10.1021/acsinfecdis.9b00073

Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential

2019

Journal Article

Discovery and characterization of cyclic and acyclic trypsin inhibitors from Momordica dioica

Du, Junqiao, Chan, Lai Yue, Poth, Aaron G. and Craik, David J. (2019). Discovery and characterization of cyclic and acyclic trypsin inhibitors from Momordica dioica. Journal of Natural Products, 82 (2) acs.jnatprod.8b00716, 293-300. doi: 10.1021/acs.jnatprod.8b00716

Discovery and characterization of cyclic and acyclic trypsin inhibitors from Momordica dioica

2018

Journal Article

Discovery and characterization of cyclotides from Rinorea species

Niyomploy, Ploypat, Chan, Lai Yue, Harvey, Peta J., Poth, Aaron G., Colgrave, Michelle L. and Craik, David J. (2018). Discovery and characterization of cyclotides from Rinorea species. Journal of Natural Products, 81 (11) acs.jnatprod.8b00572, 2512-2520. doi: 10.1021/acs.jnatprod.8b00572

Discovery and characterization of cyclotides from Rinorea species

2018

Journal Article

A computationally designed peptide derived from Escherichia coli as a potential drug template for antibacterial and antibiofilm therapies

Cardoso, Marlon, Cândido, Elizabete, Chan, Lai, Torres, Marcelo Der Torossian, Oshiro, Karen, Rezende, Samilla, Porto, William F., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2018). A computationally designed peptide derived from Escherichia coli as a potential drug template for antibacterial and antibiofilm therapies. ACS Infectious Diseases, 4 (12) acsinfecdis.8b00219, 1727-1736. doi: 10.1021/acsinfecdis.8b00219

A computationally designed peptide derived from Escherichia coli as a potential drug template for antibacterial and antibiofilm therapies

2018

Journal Article

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

Past funding

  • 2017
    Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy
    The Cass Foundation Limited
    Open grant
  • 2016 - 2017
    Dr Lai Yue (Angeline) Chan - Maternity Funding (Advance Queensland Women's Academic Fund)
    Queensland Government Advance Queensland Women's Academic Fund
    Open grant

Availability

Dr Angeline Chan is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Development of novel cell penetrating peptides as cancer therapies.

    Associate Advisor

    Other advisors: Professor David Craik

  • Doctor Philosophy

    Investigating the antifungal activity of cyclotides from butterfly pea

    Associate Advisor

    Other advisors: Professor David Craik

  • Doctor Philosophy

    Expression of anti-cancer cyclotides in plant bio-factories

    Associate Advisor

    Other advisors: Professor David Craik

Completed supervision

Enquiries

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