Overview
Background
Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Availability
- Professor Peter Nestor is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctor of Philosophy, University of Cambridge
Research interests
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Cognitive neurology
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frontotemporal lobar degeneration
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progressive aphasia
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Alzheimer's disease
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Neurodegenerative diseases
Works
Search Professor Peter Nestor’s works on UQ eSpace
2015
Journal Article
Basal forebrain and hippocampus as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment-a multicenter DTI and volumetry study
Brueggen, Katharina, Dyrba, Martin, Barkhof, Frederik, Hausner, Lucrezia, Filippi, Massimo, Nestor, Peter J., Hauenstein, Karlheinz, Kloeppel, Stefan, Grothe, Michel J., Kasper, Elisabeth and Teipel, Stefan J. (2015). Basal forebrain and hippocampus as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment-a multicenter DTI and volumetry study. Journal of Alzheimers Disease, 48 (1), 197-204. doi: 10.3233/JAD-150063
2015
Journal Article
Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes
Schreiber, Stefanie, Abdulla, Susanne, Debska-Vielhaber, Grazyna, Machts, Judith, Dannhardt-Stieger, Verena, Feistner, Helmut, Oldag, Andreas, Goertler, Michael, Petri, Susanne, Kollewe, Katja, Kropf, Siegfried, Schreiber, Frank, Heinze, Hans-Jochen, Dengler, Reinhard, Nestor, Peter J. and Vielhaber, Stefan (2015). Peripheral nerve ultrasound in amyotrophic lateral sclerosis phenotypes. Muscle & Nerve, 51 (5), 669-675. doi: 10.1002/mus.24431
2014
Journal Article
Hippocampal degeneration in patients with amyotrophic lateral sclerosis
Abdulla, Susanne, Machts, Judith, Kaufmann, Joern, Patrick, Karina, Kollewe, Katja, Dengler, Reinhard, Heinze, Hans-Jochen, Petri, Susanne, Vielhaber, Stefan and Nestor, Peter J. (2014). Hippocampal degeneration in patients with amyotrophic lateral sclerosis. Neurobiology of Aging, 35 (11), 2639-2645. doi: 10.1016/j.neurobiolaging.2014.05.035
2014
Journal Article
A new fast accurate nonlinear medical image registration program including surface preserving regularization
Gruslys, Audrunas, Acosta-Cabronero, Julio, Nestor, Peter J., Williams, Guy B. and Ansorge, Richard E. (2014). A new fast accurate nonlinear medical image registration program including surface preserving regularization. IEEE Transactions on Medical Imaging, 33 (11) A6, 2118-2127. doi: 10.1109/TMI.2014.2332370
2014
Journal Article
Comparing voxel-based iterative sensitivity and voxel-based morphometry to detect abnormalities in T2-weighted MRI
Diaz-de-Grenu, Lara Z., Acosta-Cabronero, Julio, Williams, Guy B. and Nestor, Peter J. (2014). Comparing voxel-based iterative sensitivity and voxel-based morphometry to detect abnormalities in T2-weighted MRI. NeuroImage, 100, 379-384. doi: 10.1016/j.neuroimage.2014.06.030
2014
Journal Article
Diffusion tensor imaging in Alzheimer's disease: insights into the limbic-diencephalic network and methodological considerations
Acosta-Cabronero, Julio and Nestor, Peter J. (2014). Diffusion tensor imaging in Alzheimer's disease: insights into the limbic-diencephalic network and methodological considerations. Frontiers in Aging Neuroscience, 6 (SEP) 266. doi: 10.3389/fnagi.2014.00266
2014
Journal Article
Logopenic, mixed, or Alzheimer-related aphasia?
Sajjadi, Seyed Ahmad, Patterson, Karalyn and Nestor, Peter J. (2014). Logopenic, mixed, or Alzheimer-related aphasia?. Neurology, 82 (13), 1127-1131. doi: 10.1212/WNL.0000000000000271
2014
Journal Article
A brief history of voxel-based grey matter analysis in Alzheimer's disease
Diaz-de-Grenu, Lara Z., Acosta-Cabronero, Julio, Chong, Yao Feng Victor, Pereira, Joao M. S., Sajjadi, Seyed A., Williams, Guy B. and Nestor, Peter J. (2014). A brief history of voxel-based grey matter analysis in Alzheimer's disease. Journal of Alzheimers Disease, 38 (3), 647-659. doi: 10.3233/JAD-130362
2014
Journal Article
CADASIL presenting with a behavioural variant frontotemporal dementia phenotype
Alexander, S. K., Brown, J. M., Graham, A. and Nestor, P. J. (2014). CADASIL presenting with a behavioural variant frontotemporal dementia phenotype. Journal of Clinical Neuroscience, 21 (1), 165-167. doi: 10.1016/j.jocn.2013.02.025
2014
Journal Article
Central white matter degeneration in bulbar-and limb-onset amyotrophic lateral sclerosis
Cardenas-Blanco, Arturo, Machts, Judith, Acosta-Cabronero, Julio, Kaufmann, Joern, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2014). Central white matter degeneration in bulbar-and limb-onset amyotrophic lateral sclerosis. Journal of Neurology, 261 (10), 1961-1967. doi: 10.1007/s00415-014-7434-4
2013
Journal Article
In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease
Acosta-Cabronero, Julio, Williams, Guy B., Cardenas-Blanco, Arturo, Arnold, Robert J., Lupson, Victoria and Nestor, Peter J. (2013). In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease. PLoS One, 8 (11) e81093, e81093. doi: 10.1371/journal.pone.0081093
2013
Journal Article
Degenerator tau/TDP-43: rise of the machines
Nestor, Peter J. (2013). Degenerator tau/TDP-43: rise of the machines. Journal of Neurology, Neurosurgery and Psychiatry, 84 (9), 945-945. doi: 10.1136/jnnp-2012-304681
2013
Journal Article
VBM with viscous fluid registration of gray matter segments in SPM
Pereira, Joao S., Acosta-Cabronero, Julio, Pengas, George, Xiong, Li, Nestor, Peter J. and Williams, Guy B. (2013). VBM with viscous fluid registration of gray matter segments in SPM. Frontiers in Aging Neuroscience, 5 (JUL) Article 30. doi: 10.3389/fnagi.2013.00030
2013
Journal Article
The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation
Nathan, Pradeep J., Boardley, Rebecca, Scott, Nicola, Berges, Alienor, Maruff, Paul, Sivananthan, Tharani, Upton, Neil, Lowy, Martin T., Nestor, Peter J. and Lai, Robert (2013). The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation. Current Alzheimer Research, 10 (3), 240-251. doi: 10.2174/1567205011310030003
2013
Journal Article
The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder
Smith, Bradley N., Newhouse, Stephen, Shatunov, Aleksey, Vance, Caroline, Topp, Simon, Johnson, Lauren, Miller, Jack, Lee, Younbok, Troakes, Claire, Scott, Kirsten M., Jones, Ashley, Gray, Ian, Wright, Jamie, Hortobagyi, Tibor, Al-Sarraj, Safa, Rogelj, Boris, Powell, John, Lupton, Michelle, Lovestone, Simon, Sapp, Peter C., Weber, Markus, Nestor, Peter J., Schelhaas, Helenius J., ten Asbroek, Anneloor A. L. M., Silani, Vincenzo, Gellera, Cinzia, Taroni, Franco, Ticozzi, Nicola, Van den Berg, Leonard ... Shaw, Christopher E. (2013). The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. European Journal of Human Genetics, 21 (1), 102-108. doi: 10.1038/ejhg.2012.98
2013
Journal Article
Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases
Sajjadi, Seyed A., Acosta-Cabronero, Julio, Patterson, Karalyn, Diaz-de-Grenu, Lara Z., Williams, Guy B. and Nestor, Peter J. (2013). Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain, 136 (7), 2253-2261. doi: 10.1093/brain/awt118
2012
Journal Article
EFNS task force: the use of neuroimaging in the diagnosis of dementia
Filippi, M., Agosta, F., Barkhof, F., Dubois, B., Fox, N. C., Frisoni, G. B., Jack, C. R., Johannsen, P., Miller, B. L., Nestor, P. J., Scheltens, P., Sorbi, S., Teipel, S., Thompson, P. M. and Wahlund, L. -O. (2012). EFNS task force: the use of neuroimaging in the diagnosis of dementia. European Journal of Neurology, 19 (12), 1487-1501. doi: 10.1111/j.1468-1331.2012.03859.x
2012
Journal Article
Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease
Acosta-Cabronero, Julio, Alley, Stephanie, Williams, Guy B., Pengas, George and Nestor, Peter J. (2012). Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease. Plos One, 7 (11) e49072, e49072. doi: 10.1371/journal.pone.0049072
2012
Journal Article
Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia. Aphasiology, 26 (10), 1219-1237. doi: 10.1080/02687038.2012.710318
2012
Journal Article
Abnormalities of connected speech in semantic dementia vs Alzheimer's disease
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in semantic dementia vs Alzheimer's disease. Aphasiology, 26 (6), 847-866. doi: 10.1080/02687038.2012.654933
Supervision
Availability
- Professor Peter Nestor is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.
Principal Advisor
Other advisors: Associate Professor John O'Sullivan, Dr Amir Fazlollahi
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Doctor Philosophy
Clinical utility of autobiographical memory in dementia diagnoses
Principal Advisor
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Doctor Philosophy
Diagnostic specificity in frontotemporal dementia
Principal Advisor
Completed supervision
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2024
Doctor Philosophy
The `What' and `Where' of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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2025
Doctor Philosophy
Attentional Switching in Healthy Ageing and Neurodegenerative Disorders
Associate Advisor
Other advisors: Professor Gail Robinson
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Associate Advisor
Other advisors: Professor Fatima Nasrallah
Media
Enquiries
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