
Overview
Background
Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Availability
- Professor Peter Nestor is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctor of Philosophy, University of Cambridge
Research interests
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Cognitive neurology
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frontotemporal lobar degeneration
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progressive aphasia
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Alzheimer's disease
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Neurodegenerative diseases
Works
Search Professor Peter Nestor’s works on UQ eSpace
2013
Journal Article
VBM with viscous fluid registration of gray matter segments in SPM
Pereira, Joao S., Acosta-Cabronero, Julio, Pengas, George, Xiong, Li, Nestor, Peter J. and Williams, Guy B. (2013). VBM with viscous fluid registration of gray matter segments in SPM. Frontiers in Aging Neuroscience, 5 (JUL) Article 30. doi: 10.3389/fnagi.2013.00030
2013
Journal Article
The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation
Nathan, Pradeep J., Boardley, Rebecca, Scott, Nicola, Berges, Alienor, Maruff, Paul, Sivananthan, Tharani, Upton, Neil, Lowy, Martin T., Nestor, Peter J. and Lai, Robert (2013). The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation. Current Alzheimer Research, 10 (3), 240-251. doi: 10.2174/1567205011310030003
2013
Journal Article
The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder
Smith, Bradley N., Newhouse, Stephen, Shatunov, Aleksey, Vance, Caroline, Topp, Simon, Johnson, Lauren, Miller, Jack, Lee, Younbok, Troakes, Claire, Scott, Kirsten M., Jones, Ashley, Gray, Ian, Wright, Jamie, Hortobagyi, Tibor, Al-Sarraj, Safa, Rogelj, Boris, Powell, John, Lupton, Michelle, Lovestone, Simon, Sapp, Peter C., Weber, Markus, Nestor, Peter J., Schelhaas, Helenius J., ten Asbroek, Anneloor A. L. M., Silani, Vincenzo, Gellera, Cinzia, Taroni, Franco, Ticozzi, Nicola, Van den Berg, Leonard ... Shaw, Christopher E. (2013). The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. European Journal of Human Genetics, 21 (1), 102-108. doi: 10.1038/ejhg.2012.98
2013
Journal Article
Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases
Sajjadi, Seyed A., Acosta-Cabronero, Julio, Patterson, Karalyn, Diaz-de-Grenu, Lara Z., Williams, Guy B. and Nestor, Peter J. (2013). Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain, 136 (7), 2253-2261. doi: 10.1093/brain/awt118
2012
Journal Article
EFNS task force: the use of neuroimaging in the diagnosis of dementia
Filippi, M., Agosta, F., Barkhof, F., Dubois, B., Fox, N. C., Frisoni, G. B., Jack, C. R., Johannsen, P., Miller, B. L., Nestor, P. J., Scheltens, P., Sorbi, S., Teipel, S., Thompson, P. M. and Wahlund, L. -O. (2012). EFNS task force: the use of neuroimaging in the diagnosis of dementia. European Journal of Neurology, 19 (12), 1487-1501. doi: 10.1111/j.1468-1331.2012.03859.x
2012
Journal Article
Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease
Acosta-Cabronero, Julio, Alley, Stephanie, Williams, Guy B., Pengas, George and Nestor, Peter J. (2012). Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease. Plos One, 7 (11) e49072, e49072. doi: 10.1371/journal.pone.0049072
2012
Journal Article
Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia. Aphasiology, 26 (10), 1219-1237. doi: 10.1080/02687038.2012.710318
2012
Journal Article
Abnormalities of connected speech in semantic dementia vs Alzheimer's disease
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in semantic dementia vs Alzheimer's disease. Aphasiology, 26 (6), 847-866. doi: 10.1080/02687038.2012.654933
2012
Journal Article
Primary progressive aphasia: a tale of two syndromes and the rest
Sajjadi, S. A., Patterson, K., Arnold, R. J., Watson, P. C. and Nestor, P. J. (2012). Primary progressive aphasia: a tale of two syndromes and the rest. Neurology, 78 (21), 1670-1677. doi: 10.1212/WNL.0b013e3182574f79
2012
Journal Article
Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate
Nestor, Peter J. (2012). Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate. Journal of Neurology Neurosurgery and Psychiatry, 83 (3), 349-350. doi: 10.1136/jnnp.2010.238899
2012
Journal Article
The relationship of topographical memory performance to regional neurodegeneration in Alzheimer's disease
Pengas, George, Williams, Guy B., Acosta-Cabronero, Julio, Ash, Tom W. J., Hong, Young T., Izquierdo-Garcia, David, Fryer, Tim D., Hodges, John R. and Nestor, Peter J. (2012). The relationship of topographical memory performance to regional neurodegeneration in Alzheimer's disease. Frontiers in Aging Neuroscience, 4 (JULY) 17. doi: 10.3389/fnagi.2012.00017
2011
Journal Article
Magnetoencephalography of frontotemporal dementia: spatiotemporally localized changes during semantic decisions
Hughes, Laura E., Nestor, Peter J., Hodges, John R. and Rowe, James B. (2011). Magnetoencephalography of frontotemporal dementia: spatiotemporally localized changes during semantic decisions. Brain, 134 (9), 2513-2522. doi: 10.1093/brain/awr196
2011
Journal Article
Attenuation correction methods suitable for brain imaging with a PET/MRI scanner: A comparison of tissue atlas and template attenuation map approaches
Malone, Ian B., Ansorge, Richard E., Williams, Guy B., Nestor, Peter J., Carpenter, T. Adrian and Fryer, Tim D. (2011). Attenuation correction methods suitable for brain imaging with a PET/MRI scanner: A comparison of tissue atlas and template attenuation map approaches. Journal of Nuclear Medicine, 52 (7), 1142-1149. doi: 10.2967/jnumed.110.085076
2011
Journal Article
Atrophy, hypometabolism and white matter abnormalities in semantic dementia tell a coherent story
Acosta-Cabronero, Julio, Patterson, Karalyn, Fryer, Tim D., Hodges, John R., Pengas, George, Williams, Guy B. and Nestor, Peter J. (2011). Atrophy, hypometabolism and white matter abnormalities in semantic dementia tell a coherent story. Brain, 134 (7), 2025-2035. doi: 10.1093/brain/awr119
2011
Journal Article
Profiles of recent autobiographical memory retrieval in semantic dementia, behavioural-variant frontotemporal dementia, and Alzheimer's disease
Irish, M., Hornberger, M., Lah, S., Miller, L., Pengas, G., Nestor, P. J., Hodges, J. R. and Piguet, O. (2011). Profiles of recent autobiographical memory retrieval in semantic dementia, behavioural-variant frontotemporal dementia, and Alzheimer's disease. Neuropsychologia, 49 (9), 2694-2702. doi: 10.1016/j.neuropsychologia.2011.05.017
2011
Journal Article
Hippocampal dysfunction in patients with mild cognitive impairment: A functional neuroimaging study of a visuospatial paired associates learning task
de Rover, Mischa, Pironti, Valentino A., McCabe, Jonathan A., Acosta-Cabronero, Julio, Arana, F. Sergio, Morein-Zamir, Sharon, Hodges, John R., Robbins, Trevor W., Fletcher, Paul C., Nestor, Peter J. and Sahakian, Barbara J. (2011). Hippocampal dysfunction in patients with mild cognitive impairment: A functional neuroimaging study of a visuospatial paired associates learning task. Neuropsychologia, 49 (7), 2060-2070. doi: 10.1016/j.neuropsychologia.2011.03.037
2011
Journal Article
MRI detection of tissue pathology beyond atrophy in Alzheimer's disease: Introducing T2-VBM
Diaz-de-Grenu, Lara Z., Acosta-Cabronero, Julio, Pereira, Joao M. S., Pengas, George, Williams, Guy B. and Nestor, Peter J. (2011). MRI detection of tissue pathology beyond atrophy in Alzheimer's disease: Introducing T2-VBM. Neuroimage, 56 (4), 1946-1953. doi: 10.1016/j.neuroimage.2011.03.082
2011
Journal Article
Clinical comparison of progressive aphasia associated with Alzheimer versus FTD-spectrum pathology
Xiong, Li, Xuereb, John H., Spillantini, Maria Grazia, Patterson, Karalyn, Hodges, John R. and Nestor, Peter J. (2011). Clinical comparison of progressive aphasia associated with Alzheimer versus FTD-spectrum pathology. Journal of Neurology Neurosurgery and Psychiatry, 82 (3), 254-260. doi: 10.1136/jnnp.2010.209916
2010
Journal Article
The word processing deficit in semantic dementia: All categories are equal, but some categories are more equal than others
Pulvermueller, Friedemann, Cooper-Pye, Elisa, Dine, Clare, Hauk, Olaf, Nestor, Peter J. and Patterson, Karalyn (2010). The word processing deficit in semantic dementia: All categories are equal, but some categories are more equal than others. Journal of Cognitive Neuroscience, 22 (9), 2027-2041. doi: 10.1162/jocn.2009.21339
2010
Journal Article
Editorial: Dementia in Lewy body syndromes: A battle between hearts and minds
Nestor, Peter J. (2010). Editorial: Dementia in Lewy body syndromes: A battle between hearts and minds. Neurology, 74 (11), 872-873. doi: 10.1212/WNL.0b013e3181d55f79
Supervision
Availability
- Professor Peter Nestor is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.
Principal Advisor
Other advisors: Associate Professor John O'Sullivan
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Doctor Philosophy
Clinical utility of autobiographical memory in dementia diagnoses
Principal Advisor
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Doctor Philosophy
The `What¿ and `Where¿ of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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Doctor Philosophy
Diagnostic specificity in frontotemporal dementia
Principal Advisor
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Doctor Philosophy
Attentional Switching in Healthy Ageing and Neurodegenerative Disorders
Associate Advisor
Other advisors: Professor Gail Robinson
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Doctor Philosophy
Cognitive switching in ageing and preclinical neurodegenerative disorders
Associate Advisor
Other advisors: Professor Gail Robinson
Completed supervision
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2024
Doctor Philosophy
The `What' and `Where' of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
Media
Enquiries
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