Overview
Background
Prof Nestor joined the Queensland Brain Institute in October/2017 and has a conjoint appointment as a cognitive neurologist at Mater Misericordiae Ltd (Mater Hospital).
His particular interests include understanding the earliest stages of Alzheimer's disease (i.e. before dementia is established); atypical forms of dementia with a particular focus on primary progressive aphasia and dementias related to Parkinson's and Lewy body diseases; and improving differential diagnosis between the major categories of neurodegenerative diseases.
He works on development of neuropsychological tests of cognition, both to accurately track change over time and improve diagnostic accuracy between the major diseases causing dementia. He also uses multi-modal imaging (magnetic resonance imaging [MRI] and positron emission tomography [PET]) to understand the sequence of events occurring in degenerative brain diseases (particularly Alzheimer's disease, frontotemporal dementia, Parkinson's disease, motor neuron disease [ALS], progressive supranuclear palsy [PSP] and corticobasal degeneration [CBD]) and identify novel biomarkers. A major focus of his is on developing novel approaches to MR imaging for single subject pathological diagnoses that can be exported into the everyday clinical setting; recent examples include diffusion tensor imaging to identify PSP and CBD (Sajjadi et al, 2013) and quantitative susceptibility mapping in Parkinson's disease (Acosta-Cabornero et al, 2013).
Availability
- Professor Peter Nestor is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctor of Philosophy, University of Cambridge
Research interests
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Cognitive neurology
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frontotemporal lobar degeneration
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progressive aphasia
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Alzheimer's disease
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Neurodegenerative diseases
Works
Search Professor Peter Nestor’s works on UQ eSpace
2014
Journal Article
Diffusion tensor imaging in Alzheimer's disease: insights into the limbic-diencephalic network and methodological considerations
Acosta-Cabronero, Julio and Nestor, Peter J. (2014). Diffusion tensor imaging in Alzheimer's disease: insights into the limbic-diencephalic network and methodological considerations. Frontiers in Aging Neuroscience, 6 (SEP) 266. doi: 10.3389/fnagi.2014.00266
2014
Journal Article
Logopenic, mixed, or Alzheimer-related aphasia?
Sajjadi, Seyed Ahmad, Patterson, Karalyn and Nestor, Peter J. (2014). Logopenic, mixed, or Alzheimer-related aphasia?. Neurology, 82 (13), 1127-1131. doi: 10.1212/WNL.0000000000000271
2014
Journal Article
CADASIL presenting with a behavioural variant frontotemporal dementia phenotype
Alexander, S. K., Brown, J. M., Graham, A. and Nestor, P. J. (2014). CADASIL presenting with a behavioural variant frontotemporal dementia phenotype. Journal of Clinical Neuroscience, 21 (1), 165-167. doi: 10.1016/j.jocn.2013.02.025
2014
Journal Article
Central white matter degeneration in bulbar-and limb-onset amyotrophic lateral sclerosis
Cardenas-Blanco, Arturo, Machts, Judith, Acosta-Cabronero, Julio, Kaufmann, Joern, Abdulla, Susanne, Kollewe, Katja, Petri, Susanne, Heinze, Hans-Jochen, Dengler, Reinhard, Vielhaber, Stefan and Nestor, Peter J. (2014). Central white matter degeneration in bulbar-and limb-onset amyotrophic lateral sclerosis. Journal of Neurology, 261 (10), 1961-1967. doi: 10.1007/s00415-014-7434-4
2014
Journal Article
A brief history of voxel-based grey matter analysis in Alzheimer's disease
Diaz-de-Grenu, Lara Z., Acosta-Cabronero, Julio, Chong, Yao Feng Victor, Pereira, Joao M. S., Sajjadi, Seyed A., Williams, Guy B. and Nestor, Peter J. (2014). A brief history of voxel-based grey matter analysis in Alzheimer's disease. Journal of Alzheimers Disease, 38 (3), 647-659. doi: 10.3233/JAD-130362
2013
Journal Article
In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease
Acosta-Cabronero, Julio, Williams, Guy B., Cardenas-Blanco, Arturo, Arnold, Robert J., Lupson, Victoria and Nestor, Peter J. (2013). In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease. PLoS One, 8 (11) e81093, e81093. doi: 10.1371/journal.pone.0081093
2013
Journal Article
Degenerator tau/TDP-43: rise of the machines
Nestor, Peter J. (2013). Degenerator tau/TDP-43: rise of the machines. Journal of Neurology, Neurosurgery and Psychiatry, 84 (9), 945-945. doi: 10.1136/jnnp-2012-304681
2013
Journal Article
VBM with viscous fluid registration of gray matter segments in SPM
Pereira, Joao S., Acosta-Cabronero, Julio, Pengas, George, Xiong, Li, Nestor, Peter J. and Williams, Guy B. (2013). VBM with viscous fluid registration of gray matter segments in SPM. Frontiers in Aging Neuroscience, 5 (JUL) Article 30. doi: 10.3389/fnagi.2013.00030
2013
Journal Article
The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation
Nathan, Pradeep J., Boardley, Rebecca, Scott, Nicola, Berges, Alienor, Maruff, Paul, Sivananthan, Tharani, Upton, Neil, Lowy, Martin T., Nestor, Peter J. and Lai, Robert (2013). The Safety, Tolerability, Pharmacokinetics and Cognitive Effects of GSK239512, a Selective Histamine H-3 Receptor Antagonist in Patients with Mild to Moderate Alzheimer's Disease: A Preliminary Investigation. Current Alzheimer Research, 10 (3), 240-251. doi: 10.2174/1567205011310030003
2013
Journal Article
Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases
Sajjadi, Seyed A., Acosta-Cabronero, Julio, Patterson, Karalyn, Diaz-de-Grenu, Lara Z., Williams, Guy B. and Nestor, Peter J. (2013). Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain, 136 (7), 2253-2261. doi: 10.1093/brain/awt118
2013
Journal Article
The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder
Smith, Bradley N., Newhouse, Stephen, Shatunov, Aleksey, Vance, Caroline, Topp, Simon, Johnson, Lauren, Miller, Jack, Lee, Younbok, Troakes, Claire, Scott, Kirsten M., Jones, Ashley, Gray, Ian, Wright, Jamie, Hortobagyi, Tibor, Al-Sarraj, Safa, Rogelj, Boris, Powell, John, Lupton, Michelle, Lovestone, Simon, Sapp, Peter C., Weber, Markus, Nestor, Peter J., Schelhaas, Helenius J., ten Asbroek, Anneloor A. L. M., Silani, Vincenzo, Gellera, Cinzia, Taroni, Franco, Ticozzi, Nicola, Van den Berg, Leonard ... Shaw, Christopher E. (2013). The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. European Journal of Human Genetics, 21 (1), 102-108. doi: 10.1038/ejhg.2012.98
2012
Journal Article
EFNS task force: the use of neuroimaging in the diagnosis of dementia
Filippi, M., Agosta, F., Barkhof, F., Dubois, B., Fox, N. C., Frisoni, G. B., Jack, C. R., Johannsen, P., Miller, B. L., Nestor, P. J., Scheltens, P., Sorbi, S., Teipel, S., Thompson, P. M. and Wahlund, L. -O. (2012). EFNS task force: the use of neuroimaging in the diagnosis of dementia. European Journal of Neurology, 19 (12), 1487-1501. doi: 10.1111/j.1468-1331.2012.03859.x
2012
Journal Article
Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease
Acosta-Cabronero, Julio, Alley, Stephanie, Williams, Guy B., Pengas, George and Nestor, Peter J. (2012). Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease. Plos One, 7 (11) e49072, e49072. doi: 10.1371/journal.pone.0049072
2012
Journal Article
Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in the non-semantic variants of primary progressive aphasia. Aphasiology, 26 (10), 1219-1237. doi: 10.1080/02687038.2012.710318
2012
Journal Article
Abnormalities of connected speech in semantic dementia vs Alzheimer's disease
Sajjadi, Seyed Ahmad, Patterson, Karalyn, Tomek, Michal and Nestor, Peter J. (2012). Abnormalities of connected speech in semantic dementia vs Alzheimer's disease. Aphasiology, 26 (6), 847-866. doi: 10.1080/02687038.2012.654933
2012
Journal Article
Primary progressive aphasia: a tale of two syndromes and the rest
Sajjadi, S. A., Patterson, K., Arnold, R. J., Watson, P. C. and Nestor, P. J. (2012). Primary progressive aphasia: a tale of two syndromes and the rest. Neurology, 78 (21), 1670-1677. doi: 10.1212/WNL.0b013e3182574f79
2012
Journal Article
Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate
Nestor, Peter J. (2012). Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate. Journal of Neurology Neurosurgery and Psychiatry, 83 (3), 349-350. doi: 10.1136/jnnp.2010.238899
2012
Journal Article
The relationship of topographical memory performance to regional neurodegeneration in Alzheimer's disease
Pengas, George, Williams, Guy B., Acosta-Cabronero, Julio, Ash, Tom W. J., Hong, Young T., Izquierdo-Garcia, David, Fryer, Tim D., Hodges, John R. and Nestor, Peter J. (2012). The relationship of topographical memory performance to regional neurodegeneration in Alzheimer's disease. Frontiers in Aging Neuroscience, 4 (JULY) 17. doi: 10.3389/fnagi.2012.00017
2011
Journal Article
Magnetoencephalography of frontotemporal dementia: spatiotemporally localized changes during semantic decisions
Hughes, Laura E., Nestor, Peter J., Hodges, John R. and Rowe, James B. (2011). Magnetoencephalography of frontotemporal dementia: spatiotemporally localized changes during semantic decisions. Brain, 134 (9), 2513-2522. doi: 10.1093/brain/awr196
2011
Journal Article
Atrophy, hypometabolism and white matter abnormalities in semantic dementia tell a coherent story
Acosta-Cabronero, Julio, Patterson, Karalyn, Fryer, Tim D., Hodges, John R., Pengas, George, Williams, Guy B. and Nestor, Peter J. (2011). Atrophy, hypometabolism and white matter abnormalities in semantic dementia tell a coherent story. Brain, 134 (7), 2025-2035. doi: 10.1093/brain/awr119
Supervision
Availability
- Professor Peter Nestor is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
The evolution of cognitive deficits in Lewy body disorders and related degenerative diseases.
Principal Advisor
Other advisors: Associate Professor John O'Sullivan, Dr Amir Fazlollahi
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Doctor Philosophy
Clinical utility of autobiographical memory in dementia diagnoses
Principal Advisor
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Doctor Philosophy
Diagnostic specificity in frontotemporal dementia
Principal Advisor
Completed supervision
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2024
Doctor Philosophy
The `What' and `Where' of Visual Processing in Neurodegeneration: The essential yet overlooked component of diagnostic testing in dementia
Principal Advisor
Other advisors: Professor Jason Mattingley
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2025
Doctor Philosophy
Attentional Switching in Healthy Ageing and Neurodegenerative Disorders
Associate Advisor
Other advisors: Professor Gail Robinson
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Associate Advisor
Other advisors: Professor Fatima Nasrallah
Media
Enquiries
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