
Overview
Background
Professor Peter Sly is the Director, Children's Health and Environment Program. Professor Sly is a NHMRC Leadership Fellow (L3) and an emeritus paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. Professor Sly’s research aims to understand the mechanisms underlying chronic childhood lung diseases in order to improve clinical management and to delay or prevent their onset, with consequent reductions in adult lung diseases. A combination of basic science, longitudinal cohort studies and translation of research findings into clinical practice, including clinical trials, are included in three main areas: asthma, cystic fibrosis and children’s environmental health
Professor Sly is an advisor to the World Health Organisation Department of Public Health, Environmental and Social Determinants of Disease and currently serves on International Advisory Boards and committees, including: WHO network of Collaborating Centres in Children’s Environmental Health; Canadian Healthy Infant Longitudinal Development (CHILD) Study, Canada; the Infant Lung Health Study, Paarl, South Africa; and A SHARED Future: Achieving Strength, Health, and Autonomy, through Renewable Energy Development for the Future.
Availability
- Professor Peter Sly is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctoral Diploma of Medicine, University of Melbourne
- Doctoral Diploma of Science (Advanced), University of Western Australia
Research interests
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Asthma
Understanding mechanisms that underlie risks for developing asthma in susceptible children
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Cystic Fibrosis
Understanding the mechanisms underlying the development of lung disease early in life and why and how this progresses
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Impact of environmental exposures in early life
Improving methods of assessing environmental exposures during fetal development and in early postnatal life. Improving methods for assessing the effects of early life environmental exposures and understanding how these increase long-tern risk of chronic disease.
Works
Search Professor Peter Sly’s works on UQ eSpace
2020
Journal Article
Variants associated withHHIP expression have sex-differential effects on lung function
Fawcett, Katherine A., Wain, Louise V., Obeidat, Ma'en, Melbourne, Carl, Shrine, Nick, Guyatt, Anna L., John, Catherine, Luan, Jian'an, Richmond, Anne, Moksnes, Marta R., Granell, Raquel, Weiss, Stefan, Imboden, Medea, May-Wilson, Sebastian, Hysi, Pirro, Boutin, Thibaud S., Portas, Laura, Flexeder, Claudia, Harris, Sarah E., Wang, Carol A., Lyytikäinen, Leo-Pekka, Palviainen, Teemu, Foong, Rachel E., Keidel, Dirk, Minelli, Cosetta, Langenberg, Claudia, Bossé, Yohan, Van den Berge, Maarten, Sin, Don D. ... Tobin, Martin D. (2020). Variants associated withHHIP expression have sex-differential effects on lung function. Wellcome Open Research, 5 111, 1-19. doi: 10.12688/wellcomeopenres.15846.1
2020
Journal Article
Systems biology and big data in asthma and allergy: recent discoveries and emerging challenges
Tang, Howard H. F., Sly, Peter D., Holt, Patrick G., Holt, Kathryn E. and Inouye, Michael (2020). Systems biology and big data in asthma and allergy: recent discoveries and emerging challenges. The European Respiratory Journal, 55 (1) 1900844, 1900844. doi: 10.1183/13993003.00844-2019
2020
Journal Article
The association of early life viral respiratory illness and atopy on asthma in children: systematic review and meta-analysis
Wadhwa, Vikas, Lodge, Caroline J., Dharmage, Shyamali C., Cassim, Raisa, Sly, Peter D. and Russell, Melissa Anne (2020). The association of early life viral respiratory illness and atopy on asthma in children: systematic review and meta-analysis. Journal of Allergy and Clinical Immunology: In Practice, 8 (8), 2663-2672.e7. doi: 10.1016/j.jaip.2020.03.032
2020
Conference Publication
The effect of oxidative stress on human airway epithelial cells
Yamamoto, A., Yeo, A. J., Deane, A., Sly, P. D. and Fantino, E. (2020). The effect of oxidative stress on human airway epithelial cells. International Conference of the American-Thoracic-Society, Electr Network, 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2304
2020
Journal Article
Genetic variation, intrauterine growth, and adverse pregnancy conditions predict leptin gene DNA methylation in blood at birth and 12 months of age
Mansell, Toby, Ponsonby, Anne-Louise, Collier, Fiona, Burgner, David, Vuillermin, Peter, Lange, Katherine, Ryan, Joanne, Saffery, Richard, Vuillermin, Peter, Ponsonby, Anne-Louise, Carlin, John, Allen, Katie, Tang, Mimi, Saffery, Richard, Ranganathan, Sarath, Burgner, David, Dwyer, Terry, Jachno, Kim and Sly, Peter (2020). Genetic variation, intrauterine growth, and adverse pregnancy conditions predict leptin gene DNA methylation in blood at birth and 12 months of age. International Journal of Obesity, 44 (1), 45-56. doi: 10.1038/s41366-019-0472-3
2019
Journal Article
Deserters on the atopic march: risk factors, immune profile, and clinical outcomes of food-sensitized-tolerant infants
Gray, Lawrence E. K., Ponsonby, Anne-Louise, Collier, Fiona, O'Hely, Martin, Sly, Peter D., Ranganathan, Sarath, Tang, Mimi L. K., Carlin, John B., Saffery, Richard, Vuillermin, Peter J., Burgner, David, Allen, Katrina J. and Pezic, Angela (2019). Deserters on the atopic march: risk factors, immune profile, and clinical outcomes of food-sensitized-tolerant infants. Allergy, 75 (6) all.14159, 1404-1413. doi: 10.1111/all.14159
2019
Journal Article
Early life microbial exposure, child neurocognition and behaviour at 2 years of age: A birth cohort study
Senn, Elizabeth, Symeonides, Christos, Vuillermin, Peter, Ponsonby, Anne-Louise, Carlin, John, Tang, Mimi, Collier, Fiona, Dwyer, Terry, Ranganathan, Sarath, Sly, Peter, Harrison, Len and Burgner, David (2019). Early life microbial exposure, child neurocognition and behaviour at 2 years of age: A birth cohort study. Journal of Paediatrics and Child Health, 56 (4), 590-599. doi: 10.1111/jpc.14695
2019
Journal Article
Pre-school child blood lead levels in a population-derived Australian birth cohort: the Barwon Infant Study
Symeonides, Christos, Vuillermin, Peter, Sly, Peter D., Collier, Fiona, Lynch, Victoria, Falconer, Sandra, Pezic, Angela, Wardrop, Nicole, Dwyer, Terence, Ranganathan, Sarath and Ponsonby, Anne-Louise B. (2019). Pre-school child blood lead levels in a population-derived Australian birth cohort: the Barwon Infant Study. Medical Journal of Australia, 212 (4) mja2.50427, 169-174. doi: 10.5694/mja2.50427
2019
Journal Article
Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections
Brealey, Jaelle C., Sly, Peter D., Young, Paul R. and Chappell, Keith J. (2019). Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections. Microbiology, 166 (1) 000870, 63-72. doi: 10.1099/mic.0.000870
2019
Journal Article
Environmentally Persistent Free Radicals: Linking Air Pollution and Poor Respiratory Health?
Sly, Peter D., Cormier, Stephania A., Lomnicki, Slawomir, Harding, Jeffrey N. and Grimwood, Keith (2019). Environmentally Persistent Free Radicals: Linking Air Pollution and Poor Respiratory Health?. American Journal of Respiratory and Critical Care Medicine, 200 (8), 1062-1063. doi: 10.1164/rccm.201903-0675LE
2019
Journal Article
Detection of expiratory flow limitation by forced oscillations during noninvasive ventilation
Sly, Peter D., Cormier, Stephania A., Lomnicki, Slawomir, Harding, Jeffrey N. and Grimwood, Keith (2019). Detection of expiratory flow limitation by forced oscillations during noninvasive ventilation. American Journal of Respiratory and Critical Care Medicine, 200 (8), 1063-1065. doi: 10.1164/rccm.201903-0570LE
2019
Journal Article
Using human epidemiological analyses to support the assessment of the impacts of coal mining on health
Cortes-Ramirez, Javier, Sly, Peter D., Ng, Jack and Jagals, Paul (2019). Using human epidemiological analyses to support the assessment of the impacts of coal mining on health. Reviews on Environmental Health, 34 (4), 391-401. doi: 10.1515/reveh-2019-0033
2019
Conference Publication
Intra-breath oscillometry for assessing respiratory outcomes in preterm-born children
Cousins, Michael, Hart, Kylie, Hantos, Zoltan, Sly, Peter, Henderson, John and Kotecha, Sailesh (2019). Intra-breath oscillometry for assessing respiratory outcomes in preterm-born children. European-Respiratory-Society (ERS) International Congress, Madrid Spain, Sep 28-Oct 02, 2019. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2019.PA921
2019
Journal Article
Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM85
Sly, Peter D., Galbraith, Sally, Islam, Zahir, Holt, Barbara, Troy, Niamh and Holt, Patrick G. (2019). Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM85. Journal of Allergy and Clinical Immunology, 144 (3), 870-872. doi: 10.1016/j.jaci.2019.05.032
2019
Journal Article
Pesticide metabolite concentrations in Queensland pre-schoolers – Exposure trends related to age and sex using urinary biomarkers
Li, Yan, Wang, Xianyu, Toms, Leisa-Maree L., He, Chang, Hobson, Peter, Sly, Peter D., Aylward, Lesa L. and Mueller, Jochen F. (2019). Pesticide metabolite concentrations in Queensland pre-schoolers – Exposure trends related to age and sex using urinary biomarkers. Environmental Research, 176 108532, 108532. doi: 10.1016/j.envres.2019.108532
2019
Journal Article
Changing prevalence of lower airway infections in young children with cystic fibrosis
Breuer, Oded, Schultz, Andre, Turkovic, Lidija, De Klerk, Nicholas, Keil, Anthony D., Brennan, Siobhain, Harrison, Joanne, Robertson, Colin, Robinson, Philip J., Sly, Peter D., Ranganathan, Sarath, Stick, Stephen M. and Caudri, Daan (2019). Changing prevalence of lower airway infections in young children with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 200 (5), 590-599. doi: 10.1164/rccm.201810-1919OC
2019
Journal Article
Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children
Leffler, Jonatan, Read, James F., Jones, Anya C., Mok, Danny, Hollams, Elysia M., Laing, Ingrid A., Le Souef, Peter N., Sly, Peter D., Kusel, Merci M.H., de Klerk, Nicholas H., Bosco, Anthony, Holt, Patrick G. and Strickland, Deborah H. (2019). Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children. Pediatric Allergy and Immunology, 30 (6) pai.13063, 646-653. doi: 10.1111/pai.13063
2019
Journal Article
Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles
Jones, Anya C, Anderson, Denise, Galbraith, Sally, Fantino, Emmanuelle, Cardenas, Diana Gutierrez, Read, James F, Serralha, Michael, Holt, Barbara J, Strickland, Deborah H, Sly, Peter D, Bosco, Anthony and Holt, Patrick G (2019). Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles. Journal of Allergy and Clinical Immunology, 144 (5), 1411-1413. doi: 10.1016/j.jaci.2019.07.043
2019
Journal Article
Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine
Heffernan, A.L., Gomez-Ramos, M.J., Symeonides, C., Hare, D.J., Vijayasarathy, S., Thompson, K., Mueller, J.F., Ponsonby, A.L. and Sly, P.D. (2019). Harmonizing analytical chemistry and clinical epidemiology for human biomonitoring studies. A case-study of plastic product chemicals in urine. Chemosphere, 238 124631, 124631. doi: 10.1016/j.chemosphere.2019.124631
2019
Journal Article
Development of a questionnaire-based insecticide exposure assessment method and comparison with urinary insecticide biomarkers in young Australian children
English, Karin, Li, Yan, Jagals, Paul, Ware, Robert S., Wang, Xianyu, He, Chang, Mueller, Jochen F. and Sly, Peter D. (2019). Development of a questionnaire-based insecticide exposure assessment method and comparison with urinary insecticide biomarkers in young Australian children. Environmental Research, 178 108613, 108613. doi: 10.1016/j.envres.2019.108613
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Sly is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Characterising the Environmental Burden of E-waste and its Impacts on Children¿s and Women's Health
Principal Advisor
-
Doctor Philosophy
Maternal exposure to phthalates and allergic disease in children
Principal Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Respiratory Guidelines for the Management of Paediatric Neuromuscular Disease
Principal Advisor
Other advisors: Dr Zephanie Tyack
-
Doctor Philosophy
Characterizing the Environmental Burden and Health Impact of Electronic Waste (e-waste) in Bangladesh
Principal Advisor
-
Doctor Philosophy
Role of airway obstruction in the development of asthma
Principal Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Improving detection of pulmonary graft-vs-host disease (pGVHD) post haematopoietic stem cell transplantation (HSCT)
Associate Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Air pollution, oxidative stress and dietary antioxidants
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia: From research to policy.
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
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Doctor Philosophy
Mitigating the health impacts of air pollution in Australia. From research to policy
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
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Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Investigations into the importance of antimicrobial residues in the surveillance of antimicrobial resistance in peri-urban dairy farms of Nepal
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Providing evidence to guide public health messages during bushfire smoke events
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Evaluation of Integrated Surveillance of Antimicrobial Resistance in South and South East Asian Countries
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
Completed supervision
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2023
Doctor Philosophy
Traffic-related air pollution: impact on respiratory health and attitudes to self-protective behaviours amongst urban Vietnamese children
Principal Advisor
Other advisors: Associate Professor Phong Thai, Associate Professor Dung Phung
-
2020
Doctor Philosophy
Novel green space measures and birthweight in Queensland, Australia
Principal Advisor
Other advisors: Professor Paul Jagals, Dr Peter Baker
-
2020
Doctor Philosophy
Enteropathogen infection and Household Factors Associated with Linear Child Growth in Bangladesh
Principal Advisor
-
2019
Doctor Philosophy
Incorporating Epidemiological Studies into Integrated Environmental Health Impact Assessment of Coal Mining
Principal Advisor
Other advisors: Professor Paul Jagals
-
2019
Doctor Philosophy
Evaluating the Effects of Atmospheric Environment on Children's Health in Hanoi, Vietnam
Principal Advisor
Other advisors: Professor Jochen Mueller, Associate Professor Phong Thai, Associate Professor Dung Phung
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2018
Doctor Philosophy
Assessing Exposure of Young Australian Children to Toxicants in the Home Environment using a Web-Based Questionnaire
Principal Advisor
Other advisors: Professor Paul Jagals
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2018
Doctor Philosophy
Improving the clinical utility of the Forced Oscillation Technique in preschool-aged children
Principal Advisor
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2025
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
2023
Doctor Philosophy
Children's Environmental Health in Least Developed Countries: a modelling approach to support policy decisions
Associate Advisor
Other advisors: Professor Paul Jagals
-
2023
Doctor Philosophy
Trajectories of asthma symptom and their associations with family, neighbourhood, and psychosocial environmental factors among children in Australia
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2022
Master Philosophy
Investigating the molecular mechanisms of macrophage polarisation
Associate Advisor
Other advisors: Dr Abdullah Tarique
-
-
2021
Doctor Philosophy
Assessing Early-life Human Exposure to Selected Pesticides Using Urinary Biomarkers
Associate Advisor
Other advisors: Professor Jochen Mueller
-
2020
Doctor Philosophy
Statistical methods for analysing the health effects of prenatal exposure to mixtures of correlated endocrine-disrupting chemicals
Associate Advisor
-
2020
Doctor Philosophy
Early Life Predictors of Peak Lung function at 21 years Findings from a Longitudinal Cohort Study
Associate Advisor
Other advisors: Professor Abdullah Mamun
-
2019
Doctor Philosophy
Establishing a wound healing model in well differentiated cultures of primary human nasal epithelial cells
Associate Advisor
-
2017
Doctor Philosophy
Assessing body burden of persistent organic pollutants (POPs) in infants/toddlers through analysis of faeces
Associate Advisor
Other advisors: Professor Jochen Mueller
-
2016
Doctor Philosophy
Understanding the cellular and molecular processes that link RAGE gene-deletion with the development of pneumovirus-induced bronchiolitis and paucigranulocytic asthma
Associate Advisor
Other advisors: Honorary Professor John Upham
-
-
2016
Doctor Philosophy
The antiviral defects of the airway epithelium associated with wheeze and atopy in children and asthma in adults
Associate Advisor
-
2015
Doctor Philosophy
Immunomodulation of allergic airway inflammation by mesenchymal stem cells
Associate Advisor
-
2014
Doctor Philosophy
Acute lower respiratory infections in infants in the tropics: Environmental drivers of seasonal epidemics
Associate Advisor
Other advisors: Emeritus Professor Gail Williams
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2014
Doctor Philosophy
Assessing environmental exposures in Australian children. A case study of bisphenol A
Associate Advisor
Other advisors: Professor Jochen Mueller
Media
Enquiries
Contact Professor Peter Sly directly for media enquiries about:
- Child health
- Children and environment
- Cystic fibrosis
- Paediatric asthma
- Respiratory physiology
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