
Overview
Background
Professor Peter Sly is the Director, Children's Health and Environment Program. Professor Sly is a NHMRC Leadership Fellow (L3) and an emeritus paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. Professor Sly’s research aims to understand the mechanisms underlying chronic childhood lung diseases in order to improve clinical management and to delay or prevent their onset, with consequent reductions in adult lung diseases. A combination of basic science, longitudinal cohort studies and translation of research findings into clinical practice, including clinical trials, are included in three main areas: asthma, cystic fibrosis and children’s environmental health
Professor Sly is an advisor to the World Health Organisation Department of Public Health, Environmental and Social Determinants of Disease and currently serves on International Advisory Boards and committees, including: WHO network of Collaborating Centres in Children’s Environmental Health; Canadian Healthy Infant Longitudinal Development (CHILD) Study, Canada; the Infant Lung Health Study, Paarl, South Africa; and A SHARED Future: Achieving Strength, Health, and Autonomy, through Renewable Energy Development for the Future.
Availability
- Professor Peter Sly is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctoral Diploma of Medicine, University of Melbourne
- Doctoral Diploma of Science (Advanced), University of Western Australia
Research interests
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Asthma
Understanding mechanisms that underlie risks for developing asthma in susceptible children
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Cystic Fibrosis
Understanding the mechanisms underlying the development of lung disease early in life and why and how this progresses
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Impact of environmental exposures in early life
Improving methods of assessing environmental exposures during fetal development and in early postnatal life. Improving methods for assessing the effects of early life environmental exposures and understanding how these increase long-tern risk of chronic disease.
Works
Search Professor Peter Sly’s works on UQ eSpace
2019
Journal Article
The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis
Rosenow, Tim, Clara Mok, L., Turkovic, Lidija, Berry, Luke J., Sly, Peter D., Ranganathan, Sarath, Tiddens, Harm A.W.M. and Stick, Stephen M. (2019). The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis. European Respiratory Journal, 54 (1) 1801771, 1801771. doi: 10.1183/13993003.01771-2018
2019
Journal Article
Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia
Hu, Mingjing, Eviston, David, Hsu, Peter, Mariño, Eliana, Chidgey, Ann, Santner-Nanan, Brigitte, Wong, Kahlia, Richards, James L., Yap, Yu Anne, Collier, Fiona, Quinton, Ann, Joung, Steven, Peek, Michael, Benzie, Ron, Macia, Laurence, Wilson, David, Ponsonby, Ann-Louise, Tang, Mimi L. K., O’Hely, Martin, Daly, Norelle L., Mackay, Charles R., Dahlstrom, Jane E., Saffery, Richard, Allen, Katrina J., Ranganathan, Sarath, Burgner, David, Harrison, Leonard C., Sly, Peter, Dwyer, Terry ... Nanan, Ralph (2019). Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia. Nature Communications, 10 (1) 3031. doi: 10.1038/s41467-019-10703-1
2019
Journal Article
Early-life determinants of hypoxia-inducible factor 3A gene (HIF3A) methylation: a birth cohort study
Mansell, Toby, Ponsonby, Anne-Louise, Januar, Vania, Novakovic, Boris, Collier, Fiona, Burgner, David, Vuillermin, Peter, Ryan, Joanne, Saffery, Richard, Carlin, John, Allen, Katie, Tang, Mimi, Ranganathan, Sarath, Dwyer, Terry, Jachno, Kim and Sly, Peter (2019). Early-life determinants of hypoxia-inducible factor 3A gene (HIF3A) methylation: a birth cohort study. Clinical Epigenetics, 11 (1) 96. doi: 10.1186/s13148-019-0687-0
2019
Other Outputs
Neonatal genetics of gene expression reveal the origins of autoimmune and allergic disease risk
Huang, Qin Qin, Tang, Howard H. F., Teo, Shu Mei, Ritchie, Scott C., Nath, Artika P., Brozynska, Marta, Salim, Agus, Bakshi, Andrew, Holt, Barbara J., Mok, Danny, Khor, Chiea Chuen, Sly, Peter D., Holt, Patrick G., Holt, Kathryn E. and Inouye, Michael (2019). Neonatal genetics of gene expression reveal the origins of autoimmune and allergic disease risk. doi: 10.1101/683086
2019
Journal Article
Predicting which children have asthma: are we any closer to finding the Holy Grail?
Sly, Peter D. (2019). Predicting which children have asthma: are we any closer to finding the Holy Grail?. Respirology, 24 (6) resp.13529, 510-511. doi: 10.1111/resp.13529
2019
Journal Article
Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis
Hoskin, Teagan S., Crowther, Jennifer M., Cheung, Jeanette, Epton, Michael J., Sly, Peter D., Elder, Peter A., Dobson, Renwick C.J., Kettle, Anthony J. and Dickerhof, Nina (2019). Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis. Redox Biology, 24 101202, 101202. doi: 10.1016/j.redox.2019.101202
2019
Journal Article
High incidence of respiratory disease in Australian infants despite low rate of maternal cigarette smoking
Gray, Lawrence EK, Ponsonby, Anne-Louise, Lin, Tiffany X, O'Hely, Martin, Collier, Fiona, Ranganathan, Sarath, Sly, Peter D, Pezic, Angela, Tang, Mimi LK, Burgner, David and Vuillermin, Peter (2019). High incidence of respiratory disease in Australian infants despite low rate of maternal cigarette smoking. Journal of Paediatrics and Child Health, 55 (12) jpc.14436, 1437-1444. doi: 10.1111/jpc.14436
2019
Journal Article
Naïve regulatory T cells in infancy: Associations with perinatal factors and development of food allergy
Collier, Fiona, Ponsonby, Anne-Louise, O'Hely, Martin, Tang, Mimi L.K., Saffery, Richard, Molloy, John, Gray, Lawrence E., Ranganathan, Sarath, Burgner, David, Allen, Katrina J., Brix, Susanne, Vuillermin, Peter J., BIS Investigator Group, Sly, Peter, Harrison, Leonard C. and Dwyer, Terrence (2019). Naïve regulatory T cells in infancy: Associations with perinatal factors and development of food allergy. Allergy, 74 (9) all.13822, 1760-1768. doi: 10.1111/all.13822
2019
Journal Article
Glycoprotein acetyls (GlycA) at 12 months are associated with high-sensitivity C-reactive protein and early life inflammatory immune measures
Collier, Fiona, Ellul, Susan, Juonala, Markus, Ponsonby, Anne-Louise, Vuillermin, Peter, Saffery, Richard, Burgner, David, Carlin, John, Ranganathan, Sarath, Sly, Peter, Tang, Mimi, Allen, Katie, Harrison, Leonard C. and Dwyer, Terry (2019). Glycoprotein acetyls (GlycA) at 12 months are associated with high-sensitivity C-reactive protein and early life inflammatory immune measures. Pediatric Research, 85 (5), 584-585. doi: 10.1038/s41390-019-0307-x
2019
Journal Article
Asthma: moving toward a global children's charter
Lenney, Warren, Adachi, Yuichi, Bush, Andrew, Fischer, Gilberto B., Hong, Jianguo, Ostrem, Anders, Pedersen, Soren, Sly, Peter D., Szefler, Stanley J., Tilak, Raj, Zar, Heather J. and The GSK Global Children's Asthma Group (2019). Asthma: moving toward a global children's charter. The Lancet Respiratory Medicine, 7 (4), 299-300. doi: 10.1016/S2213-2600(19)30074-8
2019
Journal Article
Lifestyle and occupational factors affecting exposure to BTEX in municipal solid waste composting facility workers
Rafiee, Ata, Delgado-Saborit, Juana Maria, Sly, Peter D., Amiri, Hoda and Hoseini, Mohammad (2019). Lifestyle and occupational factors affecting exposure to BTEX in municipal solid waste composting facility workers. Science of the Total Environment, 656, 540-546. doi: 10.1016/j.scitotenv.2018.11.398
2019
Journal Article
Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity
Yeo, Abrey J., Henningham, Anna, Fantino, Emmanuelle, Galbraith, Sally, Krause, Lutz, Wainwright, Claire E., Sly, Peter D. and Lavin, Martin F. (2019). Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity. Scientific Reports, 9 (1) 2627, 2627. doi: 10.1038/s41598-019-38901-3
2019
Journal Article
Pollution and children's health
Landrigan, Philip J., Fuller, Richard, Fisher, Samantha, Suk, William A., Sly, Peter, Chiles, Thomas C. and Bose-O'Reilly, Stephan (2019). Pollution and children's health. Science of the Total Environment, 650 (Pt 2), 2389-2394. doi: 10.1016/j.scitotenv.2018.09.375
2019
Journal Article
Statistical methodology in studies of prenatal exposure to mixtures of endocrine-disrupting chemicals: a review of existing approaches and new alternatives
Lazarevic, Nina, Barnett, Adrian G., Sly, Peter D. and Knibbs, Luke D. (2019). Statistical methodology in studies of prenatal exposure to mixtures of endocrine-disrupting chemicals: a review of existing approaches and new alternatives. Environmental Health Perspectives, 127 (2). doi: 10.1289/EHP2207
2019
Journal Article
Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life
Gray, Diane M., Czovek, Dorottya, McMillan, Lauren, Turkovic, Lidija, Stadler, Jacob A.M., Vanker, Anessa, Radics, Bence L., Gingl, Zoltán, Hall, Graham L., Sly, Peter D., Zar, Heather J. and Hantos, Zoltán (2019). Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life. European Respiratory Journal, 53 (2) 1800998, 1800998. doi: 10.1183/13993003.00998-2018
2019
Journal Article
Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study
Vanker, Aneesa, Nduru, Polite M., Barnett, Whitney, Dube, Felix S., Sly, Peter D., Gie, Robert P., Nicol, Mark P. and Zar, Heather J. (2019). Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study. ERJ Open Research, 5 (1) 00052-2018, 00052-2018. doi: 10.1183/23120541.00052-2018
2019
Journal Article
Maternal asthma, pregnancy complications, and offspring wheeze: untangling the web
Sly, Peter D. (2019). Maternal asthma, pregnancy complications, and offspring wheeze: untangling the web. American Journal of Respiratory and Critical Care Medicine, 199 (1), 1-2. doi: 10.1164/rccm.201808-1584ed
2019
Conference Publication
Unique subpopulations of cord blood innate lymphoid cells are associated with lung function at 6 weeks of age in babies born to mothers with asthma during pregnancy
Gomes, G. M. C., Belinelo, P. G., Starkey, M. R., Jesson, K., Loering, S., Hansbro, P. M., Murphy, V. E., Hardaker, K., Robinson, P. D., Sly, P. D., Gibson, P. G., Mattes, J. and Collison, A. M. (2019). Unique subpopulations of cord blood innate lymphoid cells are associated with lung function at 6 weeks of age in babies born to mothers with asthma during pregnancy. Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Lisbon, Portugal, 1-05 June, 2019. Hoboken, NJ United States: Wiley-Blackwell Publishing.
2019
Book
Kendig's disorders of the respiratory tract in children
Wilmott, Robert William, Bush, Andrew, Deterding, Robin, Ratjen, Felix, Sly, Peter, Zar, Heather J. and Albert Li, eds. (2019). Kendig's disorders of the respiratory tract in children. 9th ed. Philadelphia, PA, United States: Elsevier. doi: 10.1016/C2015-0-01292-8
2019
Journal Article
Children’s environmental health in south and southeast Asia: networking for better child health outcomes
Sly, Peter D., Trottier, Brittany, Carpenter, David, Cha’on, Ubon, Cormier, Stephania, Galluzzo, Betsy, Ghosh, Samayita, Goldizen, Fiona, Heacock, Michelle, Jagals, Paul, Joshi, Hari Datt, Kathuria, Prachi, Ha, Le Thai, Magsumbol, Melina S., Navasumrit, Panida, Prabhakaran, Poornima, Sen, Banalata, Skelly, Chris, Suraweera, Inoka, Vong, Sathiarany, Wangdi, Chador and Suk, William A. (2019). Children’s environmental health in south and southeast Asia: networking for better child health outcomes. Annals of Global Health, 85 (1) 17. doi: 10.5334/aogh.2403
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Sly is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Characterising the Environmental Burden of E-waste and its Impacts on Children¿s and Women's Health
Principal Advisor
-
Doctor Philosophy
Maternal exposure to phthalates and allergic disease in children
Principal Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Respiratory Guidelines for the Management of Paediatric Neuromuscular Disease
Principal Advisor
Other advisors: Dr Zephanie Tyack
-
Doctor Philosophy
Characterizing the Environmental Burden and Health Impact of Electronic Waste (e-waste) in Bangladesh
Principal Advisor
-
Doctor Philosophy
Role of airway obstruction in the development of asthma
Principal Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Improving detection of pulmonary graft-vs-host disease (pGVHD) post haematopoietic stem cell transplantation (HSCT)
Associate Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Air pollution, oxidative stress and dietary antioxidants
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka¿s metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia: From research to policy.
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
-
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia. From research to policy
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
-
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Investigations into the importance of antimicrobial residues in the surveillance of antimicrobial resistance in peri-urban dairy farms of Nepal
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
Doctor Philosophy
Providing evidence to guide public health messages during bushfire smoke events
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Evaluation of Integrated Surveillance of Antimicrobial Resistance in South and South East Asian Countries
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
Completed supervision
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2023
Doctor Philosophy
Traffic-related air pollution: impact on respiratory health and attitudes to self-protective behaviours amongst urban Vietnamese children
Principal Advisor
Other advisors: Associate Professor Phong Thai, Associate Professor Dung Phung
-
2020
Doctor Philosophy
Novel green space measures and birthweight in Queensland, Australia
Principal Advisor
Other advisors: Professor Paul Jagals, Dr Peter Baker
-
2020
Doctor Philosophy
Enteropathogen infection and Household Factors Associated with Linear Child Growth in Bangladesh
Principal Advisor
-
2019
Doctor Philosophy
Incorporating Epidemiological Studies into Integrated Environmental Health Impact Assessment of Coal Mining
Principal Advisor
Other advisors: Professor Paul Jagals
-
2019
Doctor Philosophy
Evaluating the Effects of Atmospheric Environment on Children's Health in Hanoi, Vietnam
Principal Advisor
Other advisors: Professor Jochen Mueller, Associate Professor Phong Thai, Associate Professor Dung Phung
-
2018
Doctor Philosophy
Assessing Exposure of Young Australian Children to Toxicants in the Home Environment using a Web-Based Questionnaire
Principal Advisor
Other advisors: Professor Paul Jagals
-
2018
Doctor Philosophy
Improving the clinical utility of the Forced Oscillation Technique in preschool-aged children
Principal Advisor
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2025
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
-
2023
Doctor Philosophy
Children's Environmental Health in Least Developed Countries: a modelling approach to support policy decisions
Associate Advisor
Other advisors: Professor Paul Jagals
-
2023
Doctor Philosophy
Trajectories of asthma symptom and their associations with family, neighbourhood, and psychosocial environmental factors among children in Australia
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2022
Master Philosophy
Investigating the molecular mechanisms of macrophage polarisation
Associate Advisor
Other advisors: Dr Abdullah Tarique
-
-
2021
Doctor Philosophy
Assessing Early-life Human Exposure to Selected Pesticides Using Urinary Biomarkers
Associate Advisor
Other advisors: Professor Jochen Mueller
-
2020
Doctor Philosophy
Statistical methods for analysing the health effects of prenatal exposure to mixtures of correlated endocrine-disrupting chemicals
Associate Advisor
-
2020
Doctor Philosophy
Early Life Predictors of Peak Lung function at 21 years Findings from a Longitudinal Cohort Study
Associate Advisor
Other advisors: Professor Abdullah Mamun
-
2019
Doctor Philosophy
Establishing a wound healing model in well differentiated cultures of primary human nasal epithelial cells
Associate Advisor
-
2017
Doctor Philosophy
Assessing body burden of persistent organic pollutants (POPs) in infants/toddlers through analysis of faeces
Associate Advisor
Other advisors: Professor Jochen Mueller
-
2016
Doctor Philosophy
Understanding the cellular and molecular processes that link RAGE gene-deletion with the development of pneumovirus-induced bronchiolitis and paucigranulocytic asthma
Associate Advisor
Other advisors: Honorary Professor John Upham
-
-
2016
Doctor Philosophy
The antiviral defects of the airway epithelium associated with wheeze and atopy in children and asthma in adults
Associate Advisor
-
2015
Doctor Philosophy
Immunomodulation of allergic airway inflammation by mesenchymal stem cells
Associate Advisor
-
2014
Doctor Philosophy
Acute lower respiratory infections in infants in the tropics: Environmental drivers of seasonal epidemics
Associate Advisor
Other advisors: Emeritus Professor Gail Williams
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2014
Doctor Philosophy
Assessing environmental exposures in Australian children. A case study of bisphenol A
Associate Advisor
Other advisors: Professor Jochen Mueller
Media
Enquiries
Contact Professor Peter Sly directly for media enquiries about:
- Child health
- Children and environment
- Cystic fibrosis
- Paediatric asthma
- Respiratory physiology
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