
Overview
Background
Professor Peter Sly is the Director, Children's Health and Environment Program. Professor Sly is a NHMRC Leadership Fellow (L3) and an emeritus paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. Professor Sly’s research aims to understand the mechanisms underlying chronic childhood lung diseases in order to improve clinical management and to delay or prevent their onset, with consequent reductions in adult lung diseases. A combination of basic science, longitudinal cohort studies and translation of research findings into clinical practice, including clinical trials, are included in three main areas: asthma, cystic fibrosis and children’s environmental health
Professor Sly is an advisor to the World Health Organisation Department of Public Health, Environmental and Social Determinants of Disease and currently serves on International Advisory Boards and committees, including: WHO network of Collaborating Centres in Children’s Environmental Health; Canadian Healthy Infant Longitudinal Development (CHILD) Study, Canada; the Infant Lung Health Study, Paarl, South Africa; and A SHARED Future: Achieving Strength, Health, and Autonomy, through Renewable Energy Development for the Future.
Availability
- Professor Peter Sly is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctoral Diploma of Medicine, University of Melbourne
- Doctoral Diploma of Science (Advanced), University of Western Australia
Research interests
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Asthma
Understanding mechanisms that underlie risks for developing asthma in susceptible children
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Cystic Fibrosis
Understanding the mechanisms underlying the development of lung disease early in life and why and how this progresses
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Impact of environmental exposures in early life
Improving methods of assessing environmental exposures during fetal development and in early postnatal life. Improving methods for assessing the effects of early life environmental exposures and understanding how these increase long-tern risk of chronic disease.
Works
Search Professor Peter Sly’s works on UQ eSpace
2011
Journal Article
Useful models of asthma need to properly phenotype airway narrowing
Hantos, Zoltan, Lundblad, Lennart, Bates, Jason, Irvin, Charles, Sly, Peter and Mitzner, Wayne (2011). Useful models of asthma need to properly phenotype airway narrowing. American Journal of Respiratory Cell and Molecular Biology, 45 (6), 1272-1272. doi: 10.1165/ajrcmb.45.6.1272
2011
Journal Article
Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependent
Boylen, Catherine E., Sly, Peter D., Zosky, Graeme R. and Larcombe, Alexander N. (2011). Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependent. Inhalation Toxicology, 23 (14), 906-917. doi: 10.3109/08958378.2011.625454
2011
Journal Article
Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study
Hollams, E.M., Hart, P.H., Holt, B.J., Serralha, M., Parsons, F., de Klerk, N.H., Zhang, G., Sly, P.D. and Holt, P.G. (2011). Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study. European Respiratory Journal, 38 (6), 1320-1327. doi: 10.1183/09031936.00029011
2011
Journal Article
Medical Research Results in the General Media: worthwhile and rewarding if presented well, potentially harmful if prepared poorly
Sly, Peter D. and Brand, Paul L.P. (2011). Medical Research Results in the General Media: worthwhile and rewarding if presented well, potentially harmful if prepared poorly. Paediatric Respiratory Reviews, 12 (4), 277-280. doi: 10.1016/j.prrv.2011.01.013
2011
Journal Article
Exhaled breath temperature in healthy children is influenced by room temperature and lung volume
Logie, Karla M., Kusel, Merci M.H., Sly, Peter D. and Hall, Graham L. (2011). Exhaled breath temperature in healthy children is influenced by room temperature and lung volume. Pediatric Pulmonology, 46 (11), 1062-1068. doi: 10.1002/ppul.21488
2011
Journal Article
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Artigas, M.S., Loth, D.W., Wain, L.V., Gharib, S.A., Obeidat, M., Tang, W.B., Zhai, G.J., Zhao, J.H., Smith, A.V., Huffman, J.E., Albrecht, E., Jackson, C.M., Evans, D.M., Cadby, G., Fornage, M., Manichaikul, A., Lopez, L.M., Johnson, T., Aldrich, M.C., Aspelund, T., Barroso, I., Campbell, H., Cassano, P.A., Couper, D.J., Eiriksdottir, G., Franceschini, N., Garcia, M., Gieger, C., Gislason, G.K. ... GIANT Consortium (2011). Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nature Genetics, 43 (11), 1082-1090. doi: 10.1038/ng.941
2011
Journal Article
In utero cigarette smoke exposure impairs somatic and lung growth in BALB/c mice
Larcombe, A.N., Foong, R.E., Berry, L.J., Zosky, G.R. and Sly, P.D. (2011). In utero cigarette smoke exposure impairs somatic and lung growth in BALB/c mice. European Respiratory Journal, 38 (4), 932-938. doi: 10.1183/09031936.00156910
2011
Journal Article
Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+T cell proliferation during the induction of inhalation tolerance
Fear, Vanessa S., Burchell, Jennifer T., Lai, Siew Ping, Wikstrom, Matthew E., Blank, Fabian, von Garnier, Christophe, Turner, Debra J., Sly, Peter D., Holt, Patrick G., Strickland, Deborah S. and Stumbles, Philip A. (2011). Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+T cell proliferation during the induction of inhalation tolerance. Journal of Immunology, 187 (9), 4561-4570. doi: 10.4049/jimmunol.1004189
2011
Journal Article
Sexual dimorphism in lung function responses to acute influenza A infection
Larcombe, Alexander N., Foong, Rachel E., Bozanich, Elizabeth M., Berry, Luke J., Garratt, Luke W., Gualano, Rosa C., Jones, Jessica E., Dousha, Lovisa F., Zosky, Graeme R. and Sly, Peter D. (2011). Sexual dimorphism in lung function responses to acute influenza A infection. Influenza and Other Respiratory Viruses, 5 (5), 334-342. doi: 10.1111/j.1750-2659.2011.00236.x
2011
Journal Article
Elemental carbon exposure and lung function in schoolchildren from Mexico City
Barraza-Villarreal, A., Escamilla-Nunez, M. C., Hernandez-Cadena, L., Texcalac-Sangrador, J. L., Sienra-Monge, J. J., del Rio-Navarro, B. E., Cortez-Lugo, M., Sly, P. D. and Romieu, I. (2011). Elemental carbon exposure and lung function in schoolchildren from Mexico City. European Respiratory Journal, 38 (3), 548-552. doi: 10.1183/09031936.00111410
2011
Journal Article
Inflammatory responses to individual microorganisms in the lungs of children With Cystic Fibrosis
Gangell, Catherine, Gard, Samantha, Douglas, Tonia, Park, Judy, de Klerk, Nicholas, Keil, Tony, Brennan, Siobhain, Ranganathan, Sarath, Robins-Browne, Roy, Sly, Peter D. and on behalf of AREST CF (2011). Inflammatory responses to individual microorganisms in the lungs of children With Cystic Fibrosis. Clinical Infectious Diseases, 53 (5), 425-432. doi: 10.1093/cid/cir399
2011
Journal Article
Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis Diagnosed following Newborn Screening
Hall, Graham L., Logie, Karla M., Parsons, Faith, Schulzke, Sven M., Nolan, Gary, Murray, Conor, Ranganathan, Sarah, Robinson, Phil, Sly, Peter D., Stick, Stephen M. and Arest CF (2011). Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis Diagnosed following Newborn Screening. PLoS One, 6 (8) e23932, e23932. doi: 10.1371/journal.pone.0023932
2011
Journal Article
Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic status
Collins, Rachel A., Parsons, Faith, Deverell, Marie, Hollams, Elysia M., Holt, Patrick G. and Sly, Peter D. (2011). Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic status. Journal of Allergy and Clinical Immunology, 128 (2), 301-307. doi: 10.1016/j.jaci.2011.03.016
2011
Journal Article
Infection, inflammation, and lung function decline in infants with cystic fibrosis
Pillarisetti, Naveen, Williamson, Elizabeth, Linnane, Barry, Skoric, Billy, Robertson, Colin F., Robinson, Phil, Massie, John, Hall, Graham L., Sly, Peter, Stick, Stephen, Ranganathan, Sarath and on behalf of the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) (2011). Infection, inflammation, and lung function decline in infants with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 184 (1), 75-81. doi: 10.1164/rccm.201011-1892OC
2011
Journal Article
Codetecção viral em lactentes hospitalizados com doença respiratória: Detectar é importante?
Sly, Peter D. and Jones, Carmen M. (2011). Codetecção viral em lactentes hospitalizados com doença respiratória: Detectar é importante?. Jornal De Pediatria, 87 (4), 277-280. doi: 10.2223/JPED.2117
2011
Journal Article
Validation of a school-based written questionnaire for asthma case identification in Argentina
Busi, Luciano E., Sly, Peter, Restuccia, Sebastian and Llancaman, Lidia (2011). Validation of a school-based written questionnaire for asthma case identification in Argentina. Pediatric Pulmonology, 47 (1), 1-7. doi: 10.1002/ppul.21500
2011
Journal Article
Exciting new clinical trials in cystic fibrosis: Infants need not apply
Stick, Stephen M. and Sly, Peter David (2011). Exciting new clinical trials in cystic fibrosis: Infants need not apply. American Journal of Respiratory and Critical Care Medicine, 183 (12), 1577-1578. doi: 10.1164/rccm.201102-0251ED
2011
Journal Article
Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood
Custovic, Adnan, Soderstrom, Lars, Ahlstedt, Staffan, Sly, Peter D., Simpson, Angela and Holt, Patrick G. (2011). Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood. Journal of Allergy and Clinical Immunology, 127 (6), 1480-1485. doi: 10.1016/j.jaci.2011.03.014
2011
Journal Article
Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: Operation of a lung/bone marrow axis
Holt, Patrick G. and Sly, Peter D. (2011). Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: Operation of a lung/bone marrow axis. Chest, 139 (5), 1165-1171. doi: 10.1378/chest.10-2397
2011
Journal Article
Randomised controlled trials in cystic fibrosis: what, when and how?
Sly, P.D., Ware, R.S., de Klerk, N. and Stick, S.M. (2011). Randomised controlled trials in cystic fibrosis: what, when and how?. European Respiratory Journal, 37 (5), 991-993. doi: 10.1183/09031936.00166810
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Sly is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Characterizing the Environmental Burden and Health Impact of Electronic Waste (e-waste) in Bangladesh
Principal Advisor
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Doctor Philosophy
Maternal exposure to phthalates and allergic disease in children
Principal Advisor
Other advisors: Dr Dwan Vilcins
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Doctor Philosophy
Respiratory Guidelines for the Management of Paediatric Neuromuscular Disease
Principal Advisor
Other advisors: Dr Zephanie Tyack
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Doctor Philosophy
Role of airway obstruction in the development of asthma
Principal Advisor
Other advisors: Dr Tamara Blake
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Doctor Philosophy
Air pollution, oxidative stress and dietary antioxidants
Associate Advisor
Other advisors: Dr Dwan Vilcins
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Doctor Philosophy
Providing evidence to guide public health messages during bushfire smoke events
Associate Advisor
Other advisors: Dr Dwan Vilcins
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Doctor Philosophy
Investigations into the importance of antimicrobial residues in the surveillance of antimicrobial resistance in peri-urban dairy farms of Nepal
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Improving detection of pulmonary graft-vs-host disease (pGVHD) post haematopoietic stem cell transplantation (HSCT)
Associate Advisor
Other advisors: Dr Tamara Blake, Professor Paul Robinson
Completed supervision
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2023
Doctor Philosophy
Traffic-related air pollution: impact on respiratory health and attitudes to self-protective behaviours amongst urban Vietnamese children
Principal Advisor
Other advisors: Associate Professor Phong Thai, Associate Professor Dung Phung
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2020
Doctor Philosophy
Enteropathogen infection and Household Factors Associated with Linear Child Growth in Bangladesh
Principal Advisor
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2020
Doctor Philosophy
Novel green space measures and birthweight in Queensland, Australia
Principal Advisor
Other advisors: Professor Paul Jagals, Dr Peter Baker
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2019
Doctor Philosophy
Incorporating Epidemiological Studies into Integrated Environmental Health Impact Assessment of Coal Mining
Principal Advisor
Other advisors: Professor Paul Jagals
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2019
Doctor Philosophy
Evaluating the Effects of Atmospheric Environment on Children's Health in Hanoi, Vietnam
Principal Advisor
Other advisors: Professor Jochen Mueller, Associate Professor Phong Thai, Associate Professor Dung Phung
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2018
Doctor Philosophy
Improving the clinical utility of the Forced Oscillation Technique in preschool-aged children
Principal Advisor
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2018
Doctor Philosophy
Assessing Exposure of Young Australian Children to Toxicants in the Home Environment using a Web-Based Questionnaire
Principal Advisor
Other advisors: Professor Paul Jagals
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2025
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia: From research to policy.
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
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2025
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
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2023
Doctor Philosophy
Children's Environmental Health in Least Developed Countries: a modelling approach to support policy decisions
Associate Advisor
Other advisors: Professor Paul Jagals
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2023
Doctor Philosophy
Trajectories of asthma symptom and their associations with family, neighbourhood, and psychosocial environmental factors among children in Australia
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2022
Master Philosophy
Investigating the molecular mechanisms of macrophage polarisation
Associate Advisor
Other advisors: Dr Abdullah Tarique
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2021
Doctor Philosophy
Assessing Early-life Human Exposure to Selected Pesticides Using Urinary Biomarkers
Associate Advisor
Other advisors: Professor Jochen Mueller
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2020
Doctor Philosophy
Early Life Predictors of Peak Lung function at 21 years Findings from a Longitudinal Cohort Study
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2020
Doctor Philosophy
Statistical methods for analysing the health effects of prenatal exposure to mixtures of correlated endocrine-disrupting chemicals
Associate Advisor
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2019
Doctor Philosophy
Establishing a wound healing model in well differentiated cultures of primary human nasal epithelial cells
Associate Advisor
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2017
Doctor Philosophy
Assessing body burden of persistent organic pollutants (POPs) in infants/toddlers through analysis of faeces
Associate Advisor
Other advisors: Professor Jochen Mueller
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2016
Doctor Philosophy
Understanding the cellular and molecular processes that link RAGE gene-deletion with the development of pneumovirus-induced bronchiolitis and paucigranulocytic asthma
Associate Advisor
Other advisors: Honorary Professor John Upham
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2016
Doctor Philosophy
The antiviral defects of the airway epithelium associated with wheeze and atopy in children and asthma in adults
Associate Advisor
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2015
Doctor Philosophy
Immunomodulation of allergic airway inflammation by mesenchymal stem cells
Associate Advisor
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2014
Doctor Philosophy
Acute lower respiratory infections in infants in the tropics: Environmental drivers of seasonal epidemics
Associate Advisor
Other advisors: Emeritus Professor Gail Williams
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2014
Doctor Philosophy
Assessing environmental exposures in Australian children. A case study of bisphenol A
Associate Advisor
Other advisors: Professor Jochen Mueller
Media
Enquiries
Contact Professor Peter Sly directly for media enquiries about:
- Child health
- Children and environment
- Cystic fibrosis
- Paediatric asthma
- Respiratory physiology
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