
Overview
Background
Professor Peter Sly is the Director, Children's Health and Environment Program. Professor Sly is a NHMRC Leadership Fellow (L3) and an emeritus paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. Professor Sly’s research aims to understand the mechanisms underlying chronic childhood lung diseases in order to improve clinical management and to delay or prevent their onset, with consequent reductions in adult lung diseases. A combination of basic science, longitudinal cohort studies and translation of research findings into clinical practice, including clinical trials, are included in three main areas: asthma, cystic fibrosis and children’s environmental health
Professor Sly is an advisor to the World Health Organisation Department of Public Health, Environmental and Social Determinants of Disease and currently serves on International Advisory Boards and committees, including: WHO network of Collaborating Centres in Children’s Environmental Health; Canadian Healthy Infant Longitudinal Development (CHILD) Study, Canada; the Infant Lung Health Study, Paarl, South Africa; and A SHARED Future: Achieving Strength, Health, and Autonomy, through Renewable Energy Development for the Future.
Availability
- Professor Peter Sly is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, University of Melbourne
- Doctoral Diploma of Medicine, University of Melbourne
- Doctoral Diploma of Science (Advanced), University of Western Australia
Research interests
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Asthma
Understanding mechanisms that underlie risks for developing asthma in susceptible children
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Cystic Fibrosis
Understanding the mechanisms underlying the development of lung disease early in life and why and how this progresses
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Impact of environmental exposures in early life
Improving methods of assessing environmental exposures during fetal development and in early postnatal life. Improving methods for assessing the effects of early life environmental exposures and understanding how these increase long-tern risk of chronic disease.
Works
Search Professor Peter Sly’s works on UQ eSpace
2010
Journal Article
Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study
Holt, Patrick G., Rowe, Julie, Kusel, Merci, Parsons, Faith, Hollams, Elysia M., Bosco, Anthony, McKenna, Kathy, Subrata, Lily, de Klerk, Nicholas, Serralha, Michael, Holt, Barbara J., Zhang, Guicheng, Loh, Richard, Ahlstedt, Staffan and Sly, Peter D. (2010). Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study. Journal of Allergy and Clinical Immunology, 125 (3), 653-659. doi: 10.1016/j.jaci.2009.12.018
2010
Book Chapter
Developmental physiology : Lung function during growth and development from birth to old age
Calogero, C. and Sly, P. D. (2010). Developmental physiology : Lung function during growth and development from birth to old age. Paediatric lung function. (pp. 1-15) Shieffield, United Kingdom: European Respiratory Society. doi: 10.1183/1025448x.00011109
2010
Journal Article
Toll-like receptor 7 function is reduced in adolescents with asthma
Roponen, M., Yerkovich, S. T., Hollams, E., Sly, P. D., Holt, P. G. and Upham, J. W. (2010). Toll-like receptor 7 function is reduced in adolescents with asthma. European Respiratory Journal, 35 (1), 64-71. doi: 10.1183/09031936.00172008
2010
Journal Article
The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze
Schultz, A., Devadason, S.G., Savenije, O.E.M., Sly, P.D., Le Souef, P.N. and Brand, P.L.P. (2010). The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze. Acta Paediatrica, 99 (1), 56-60. doi: 10.1111/j.1651-2227.2009.01508.x
2009
Journal Article
Frequent nocturnal awakening in early life is associated with nonatopic asthma in children
Kozyrskyj, A. L., Kendall, G. E., Zubrick, S. R., Newnham, J. P. and Sly, P. D. (2009). Frequent nocturnal awakening in early life is associated with nonatopic asthma in children. European Respiratory Journal, 34 (6), 1288-1295. doi: 10.1183/09031936.00040509
2009
Journal Article
Lung volume recruitment maneuvers and respiratory system mechanics in mechanically ventilated mice
Cannizzaro, Vincenzo, Berry, Luke J., Nicholls, Phillip K., Zosky, Graeme R., Turner, Debra J., Hantos, Zoltan and Sly, Peter D. (2009). Lung volume recruitment maneuvers and respiratory system mechanics in mechanically ventilated mice. Respiratory Physiology & Neurobiology, 169 (3), 243-251. doi: 10.1016/j.resp.2009.09.012
2009
Journal Article
Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: Potential role in maturation of the naive immune system
Tulic, Meri K., Sly, Peter D., Andrews, David, Crook, Maxine, Davoine, Francis, Odemuyiwa, Solomon O., Charles, Adrian, Hodder, Megan L., Prescott, Susan L., Holt, Patrick G. and Moqbel, Redwan (2009). Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: Potential role in maturation of the naive immune system. American Journal of Pathology, 175 (5), 2043-2052. doi: 10.2353/ajpath.2009.090015
2009
Journal Article
Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection
Zosky, Graeme R., Cannizzaro, Vincenzo, Hantos, Zoltan and Sly, Peter D. (2009). Protective mechanical ventilation does not exacerbate lung function impairment or lung inflammation following influenza A infection. Journal of Applied Physiology, 107 (5), 1472-1478. doi: 10.1152/japplphysiol.00393.2009
2009
Journal Article
Bronchiectasis in Infants and Preschool Children Diagnosed with Cystic Fibrosis after Newborn Screening
Stick, Stephen M., Brennan, Siobhain, Murray, Conor, Douglas, Tonia, von Ungern-Sternberg, Britta S., Garratt, Luke W., Gangell, Catherine L., De Klerk, Nicholas, Linnane, Barry, Ranganathan, Sarath, Robinson, Phillip, Robertson, Colin and Sly, Peter D. (2009). Bronchiectasis in Infants and Preschool Children Diagnosed with Cystic Fibrosis after Newborn Screening. Journal of Pediatrics, 155 (5), 623-628. doi: 10.1016/j.jpeds.2009.05.005
2009
Journal Article
Neutrophilic airway inflammation is a main feature of induced sputum in nonatopic asthmatic children
Drews, A. C., Pizzichini, M. M. M., Pizzichini, E., Pereira, M. U., Pitrez, P. M., Jones, M. H., Sly, P. D. and Stein, R. T. (2009). Neutrophilic airway inflammation is a main feature of induced sputum in nonatopic asthmatic children. Allergy, 64 (11), 1597-1601. doi: 10.1111/j.1398-9995.2009.02057.x
2009
Journal Article
Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing
Upham, John W., Zhang, Guicheng, Rate, Angela, Yerkovich, Stephanie T., Kusel, Merci, Sly, Peter D. and Holt, Patrick G. (2009). Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing. Journal of Allergy and Clinical Immunology, 124 (4), 707-713. doi: 10.1016/j.jaci.2009.07.009
2009
Journal Article
Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling
Hollams, Elysia M., Deverell, Marie, Serralha, Michael, Suriyaarachchi, Devinda, Parsons, Faith, Zhang, Guicheng, de Klerk, Nicholas, Holt, Barbara J., Ladyman, Claire, Sadowska, Agata, Rowe, Julie, Loh, Richard, Sly, Peter D. and Holt, Patrick G. (2009). Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling. Journal of Allergy And Clinical Immunology, 124 (3), 463-470. doi: 10.1016/j.jaci.2009.06.019
2009
Journal Article
Alveolar macrophages and the CC chemokines are increased in children with cystic fibrosis
Brennan, S., Sly, P. D., Gangell, C. L., Sturges, N., Winfield, K., Wikstrom, M., Gard, S. and Upham, J. W. (2009). Alveolar macrophages and the CC chemokines are increased in children with cystic fibrosis. The European Respiratory Journal, 34 (3), 655-661. doi: 10.1183/09031936.00178508
2009
Journal Article
Airway hyperresponsiveness is associated with activated CD4+ T cells in the airways
Zosky, Graeme R., Larcombe, Alexander N., White, Olivia J., Burchell, Jennifer T., von Garnier, Christophe, Holt, Patrick G., Turner, Debra J., Wikstrom, Matthew E., Sly, Peter D. and Stumbles, Philip A. (2009). Airway hyperresponsiveness is associated with activated CD4+ T cells in the airways. American Journal of Physiology: Lung Cellular and Molecular Physiology, 297 (2), L373-L379. doi: 10.1152/ajplung.00053.2009
2009
Journal Article
Ethical issues in measuring biomarkers in children's environmental health
Sly, Peter D., Eskenazi, Brenda, Pronczuk, Jenny, Sram, Radim, Diaz-Barriga, Fernando, Machin, Diego G., Carpenter, David O., Surdu, Simona and Meslin, Eric M. (2009). Ethical issues in measuring biomarkers in children's environmental health. Environmental Health Perspectives, 117 (8), 1185-1190. doi: 10.1289/ehp.0800480
2009
Journal Article
Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children
Subrata, Lily S., Bizzintino, Joelene, Mamessier, Emilie, Bosco, Anthony, McKenna, Katherine L., Wikstrom, Matthew E., Goldblatt, Jack, Sly, Peter D., Hales, BelindaJ, Thomas, Wayne R., Laing, Ingrid A., LeSouef, Peter N. and Holt, Patrick G. (2009). Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children. Journal of Immunology, 183 (4), 2793-2800. doi: 10.4049/jimmunol.0900695
2009
Journal Article
Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening
Sly, Peter D., Brennan, Siobhain, Gangell, Catherine, de Klerk, Nicholas, Murray, Conor, Mott, Lauren, Stick, Stephen M., Robinson, Philip J., Robertson, Colin F. and Ranganathan, Sarath C. (2009). Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. American Journal of Respiratory And Critical Care Medicine, 180 (2), 146-152. doi: 10.1164/rccm.200901-0069OC
2009
Journal Article
Bronchoscopic assessment of wheezy infants: Should this be a clinical routine?
Martinez, Manuel Soto and Sly, Peter D. (2009). Bronchoscopic assessment of wheezy infants: Should this be a clinical routine?. Salud(i)Ciencia, 16 (8), 845-847.
2009
Journal Article
Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening
Mott, Lauren S., Gangell, Catherine L., Murray, Conor P., Stick, Stephen M. and Sly, Peter D. (2009). Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening. Journal of Cystic Fibrosis, 8 (4), 285-287. doi: 10.1016/j.jcf.2009.04.009
2009
Journal Article
Application of a shortened inhaled adenosine-5′-monophosphate challenge in young children using the forced oscillation technique
Hall, Graham L., Gangell, Catherine, Fukushima, Takayoshi, Horak, Friedrich, Patterson, Hilary, Stick, Stephen M., Sly, Peter D. and Franklin, Peter J. (2009). Application of a shortened inhaled adenosine-5′-monophosphate challenge in young children using the forced oscillation technique. Chest, 136 (1), 184-189. doi: 10.1378/chest.08-2848
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Sly is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Maternal exposure to phthalates and allergic disease in children
Principal Advisor
Other advisors: Dr Dwan Vilcins
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Doctor Philosophy
Respiratory Guidelines for the Management of Paediatric Neuromuscular Disease
Principal Advisor
Other advisors: Dr Zephanie Tyack
-
Doctor Philosophy
Role of airway obstruction in the development of asthma
Principal Advisor
Other advisors: Dr Tamara Blake
-
Doctor Philosophy
Air pollution, oxidative stress and dietary antioxidants
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Providing evidence to guide public health messages during bushfire smoke events
Associate Advisor
Other advisors: Dr Dwan Vilcins
-
Doctor Philosophy
Investigations into the importance of antimicrobial residues in the surveillance of antimicrobial resistance in peri-urban dairy farms of Nepal
Associate Advisor
Other advisors: Dr Deirdre Mikkelsen, Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
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Doctor Philosophy
Improving detection of pulmonary graft-vs-host disease (pGVHD) post haematopoietic stem cell transplantation (HSCT)
Associate Advisor
Other advisors: Dr Tamara Blake, Professor Paul Robinson
Completed supervision
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2025
Doctor Philosophy
Characterizing the Environmental Burden and Health Impact of Electronic Waste (e-waste) in Bangladesh
Principal Advisor
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2023
Doctor Philosophy
Traffic-related air pollution: impact on respiratory health and attitudes to self-protective behaviours amongst urban Vietnamese children
Principal Advisor
Other advisors: Associate Professor Phong Thai, Associate Professor Dung Phung
-
2020
Doctor Philosophy
Enteropathogen infection and Household Factors Associated with Linear Child Growth in Bangladesh
Principal Advisor
-
2020
Doctor Philosophy
Novel green space measures and birthweight in Queensland, Australia
Principal Advisor
Other advisors: Professor Paul Jagals, Dr Peter Baker
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2019
Doctor Philosophy
Incorporating Epidemiological Studies into Integrated Environmental Health Impact Assessment of Coal Mining
Principal Advisor
Other advisors: Professor Paul Jagals
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2019
Doctor Philosophy
Evaluating the Effects of Atmospheric Environment on Children's Health in Hanoi, Vietnam
Principal Advisor
Other advisors: Professor Jochen Mueller, Associate Professor Phong Thai, Associate Professor Dung Phung
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2018
Doctor Philosophy
Improving the clinical utility of the Forced Oscillation Technique in preschool-aged children
Principal Advisor
-
2018
Doctor Philosophy
Assessing Exposure of Young Australian Children to Toxicants in the Home Environment using a Web-Based Questionnaire
Principal Advisor
Other advisors: Professor Paul Jagals
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2025
Doctor Philosophy
Mitigating the health impacts of air pollution in Australia: From research to policy.
Associate Advisor
Other advisors: Professor Brian Head, Associate Professor Nina Lansbury
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2025
Doctor Philosophy
Epidemiological investigations into avian influenza virus environmental contamination in live bird markets of Dhaka's metropolitan area, Bangladesh
Associate Advisor
Other advisors: Dr Nicholas Clark, Professor Ricardo Soares Magalhaes
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2023
Doctor Philosophy
Children's Environmental Health in Least Developed Countries: a modelling approach to support policy decisions
Associate Advisor
Other advisors: Professor Paul Jagals
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2023
Doctor Philosophy
Trajectories of asthma symptom and their associations with family, neighbourhood, and psychosocial environmental factors among children in Australia
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2022
Master Philosophy
Investigating the molecular mechanisms of macrophage polarisation
Associate Advisor
Other advisors: Dr Abdullah Tarique
-
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2021
Doctor Philosophy
Assessing Early-life Human Exposure to Selected Pesticides Using Urinary Biomarkers
Associate Advisor
Other advisors: Professor Jochen Mueller
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2020
Doctor Philosophy
Early Life Predictors of Peak Lung function at 21 years Findings from a Longitudinal Cohort Study
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2020
Doctor Philosophy
Statistical methods for analysing the health effects of prenatal exposure to mixtures of correlated endocrine-disrupting chemicals
Associate Advisor
-
2019
Doctor Philosophy
Establishing a wound healing model in well differentiated cultures of primary human nasal epithelial cells
Associate Advisor
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2017
Doctor Philosophy
Assessing body burden of persistent organic pollutants (POPs) in infants/toddlers through analysis of faeces
Associate Advisor
Other advisors: Professor Jochen Mueller
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2016
Doctor Philosophy
Understanding the cellular and molecular processes that link RAGE gene-deletion with the development of pneumovirus-induced bronchiolitis and paucigranulocytic asthma
Associate Advisor
Other advisors: Honorary Professor John Upham
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-
2016
Doctor Philosophy
The antiviral defects of the airway epithelium associated with wheeze and atopy in children and asthma in adults
Associate Advisor
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2015
Doctor Philosophy
Immunomodulation of allergic airway inflammation by mesenchymal stem cells
Associate Advisor
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2014
Doctor Philosophy
Acute lower respiratory infections in infants in the tropics: Environmental drivers of seasonal epidemics
Associate Advisor
Other advisors: Emeritus Professor Gail Williams
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2014
Doctor Philosophy
Assessing environmental exposures in Australian children. A case study of bisphenol A
Associate Advisor
Other advisors: Professor Jochen Mueller
Media
Enquiries
Contact Professor Peter Sly directly for media enquiries about:
- Child health
- Children and environment
- Cystic fibrosis
- Paediatric asthma
- Respiratory physiology
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