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Professor Mark Smithers
Professor

Mark Smithers

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Overview

Background

Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.

He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.

He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.

Availability

Professor Mark Smithers is:
Not available for supervision
Media expert

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Honorary Fellow, American Surgical Association, American Surgical Association
  • Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
  • Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
  • Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England

Research interests

  • Cutaneous Melanoma

    epidemiology, public health issues and management of all stages

  • Management of Oesophageal and Gastric Cancer

    Investigation and management of benign and malignant diseases of the oesophagus and the stomach.

Works

Search Professor Mark Smithers’s works on UQ eSpace

410 works between 1983 and 2025

21 - 40 of 410 works

2023

Conference Publication

Gastric filling in neoadjuvant chemoradiotherapy for oesophageal cancer

Hwang, Yang, Chen, Beini, Mai, Tao, Lee, Dominique, Thomson, Iain, Smithers, Mark and Frankel, Adam (2023). Gastric filling in neoadjuvant chemoradiotherapy for oesophageal cancer. 19th ISDE World Congress for Esophageal Diseases, Toronto, ON, Canada, 8-10 September 2023. Los Angeles, CA, United States: John Wiley & Sons. doi: 10.1093/dote/doad052.183

Gastric filling in neoadjuvant chemoradiotherapy for oesophageal cancer

2023

Journal Article

Massive mixed epithelial-stromal tumour of seminal vesicle requiring challenging abdominoperineal resection: a case report and review of literature

Yu, Zirong, Choy, Kay Tai, Ong, Ferdinand, Williams, Evan, Naidu, Sanjeev, Smithers, Bernard M., Gurung, Anjan and Lutton, Nicholas (2023). Massive mixed epithelial-stromal tumour of seminal vesicle requiring challenging abdominoperineal resection: a case report and review of literature. Journal of Surgical Case Reports, 2023 (8) rjad490, 1-3. doi: 10.1093/jscr/rjad490

Massive mixed epithelial-stromal tumour of seminal vesicle requiring challenging abdominoperineal resection: a case report and review of literature

2023

Journal Article

Individual participant data network meta-analysis of neoadjuvant chemotherapy or chemoradiotherapy in esophageal or gastroesophageal junction carcinoma

Faron, Matthieu, Cheugoua-Zanetsie, Maurice, Tierney, Jayne, Thirion, Pierre, Nankivell, Matthew, Winter, Kathryn, Yang, Hong, Shapiro, Joel, Vernerey, Dewi, Smithers, B. Mark, Walsh, Thomas, Piessen, Guillaume, Nilsson, Magnus, Boonstra, Jurjen, Ychou, Marc, Law, Simon, Cunningham, David, de Vathaire, Florent, Stahl, Michael, Urba, Susan, Valmasoni, Michele, Williaume, Danièle, Thomas, Janine, Lordick, Florian, Tepper, Joel, Roth, Jack, Gebski, Val, Burmeister, Bryan, Paoletti, Xavier ... on behalf of the MANATEC-02 Collaborative Group (2023). Individual participant data network meta-analysis of neoadjuvant chemotherapy or chemoradiotherapy in esophageal or gastroesophageal junction carcinoma. Journal of Clinical Oncology, 41 (28) jco2202279, 4535-4547. doi: 10.1200/jco.22.02279

Individual participant data network meta-analysis of neoadjuvant chemotherapy or chemoradiotherapy in esophageal or gastroesophageal junction carcinoma

2023

Journal Article

Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy

M. Naeini, Marjan, Newell, Felicity, Aoude, Lauren G., Bonazzi, Vanessa F., Patel, Kalpana, Lampe, Guy, Koufariotis, Lambros T., Lakis, Vanessa, Addala, Venkateswar, Kondrashova, Olga, Johnston, Rebecca L., Sharma, Sowmya, Brosda, Sandra, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Xu, Qinying, Thomas, Janine, Walpole, Euan, Tao Mai, G., Ackland, Stephen P., Martin, Jarad, Burge, Matthew, Finch, Robert, Karapetis, Christos S., Shannon, Jenny, Nott, Louise, Bohmer, Robert, Wilson, Kate ... Waddell, Nicola (2023). Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy. Nature Communications, 14 (1) 3155, 3155. doi: 10.1038/s41467-023-38891-x

Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy

2023

Journal Article

Quality indicators in surgery for cancer: not just the operation

Smithers, B. Mark (2023). Quality indicators in surgery for cancer: not just the operation. ANZ Journal of Surgery, 93 (7-8), 1765-1767. doi: 10.1111/ans.18516

Quality indicators in surgery for cancer: not just the operation

2023

Journal Article

The association between <scp>BRAF‐V600E</scp> mutations and death from thin (≤1.00 mm) melanomas: a nested case‐case study from Queensland, Australia

Claeson, M., Tan, S. X., Lambie, D., Brown, S., Walsh, M. D., Baade, P. D., Pandeya, N., Whitehead, K. J., Soyer, H. P., Smithers, B. M., Whiteman, D. C. and Khosrotehrani, K. (2023). The association between BRAF‐V600E mutations and death from thin (≤1.00 mm) melanomas: a nested case‐case study from Queensland, Australia. Journal of the European Academy of Dermatology and Venereology, 37 (9), e1168-e1172. doi: 10.1111/jdv.19173

The association between <scp>BRAF‐V600E</scp> mutations and death from thin (≤1.00 mm) melanomas: a nested case‐case study from Queensland, Australia

2023

Journal Article

Regarding: predicting regional lymph node recurrence in the modern age of tumor-positive sentinel node melanoma

Thompson, John F., Hyngstrom, John, Caracò, Corrado, Zager, Jonathan S., Jahkola, Tiina, Bowles, Tawnya L., Pennacchioli, Elisabetta, Hoekstra, Harald J., Moncrieff, Marc, Ingvar, Christian, van Akkooi, Alexander, Sabel, Michael S., Levine, Edward A., Henderson, Michael, Dummer, Reinhard, Rossi, Carlo Riccardo, Kane, John M., Trocha, Steven, Wright, Frances, Byrd, David R., Matter, Maurice, MacKenzie-Ross, Alastair, Kelley, Mark C., Terheyden, Patrick, Huston, Tara L., Wayne, Jeffrey D., Neuman, Heather, Smithers, B. Mark, Desai, Darius ... Faries, Mark B. (2023). Regarding: predicting regional lymph node recurrence in the modern age of tumor-positive sentinel node melanoma. Annals of Surgical Oncology, 30 (7), 4359-4360. doi: 10.1245/s10434-023-13570-9

Regarding: predicting regional lymph node recurrence in the modern age of tumor-positive sentinel node melanoma

2023

Conference Publication

Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma

Tan, S. X., Aung, T. Nwe, Claeson, M., Zhou, C., Brown, S., Acs, B., Lambie, D., Baade, P., Pandeya, N., Soyer, H., Smithers, B., Whiteman, D., Rimm, D. and Khosrotehrani, K. (2023). Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 12 - 13 May 2023. Oxford, United Kingdom: Elsevier.

Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma

2023

Journal Article

Trends and patterns of care of sentinel node biopsy in cutaneous melanoma: a population‐based study in Queensland

Wong, Jessica, Moore, Julie, Soyer, H. Peter, Mar, Victoria and Smithers, B. Mark (2023). Trends and patterns of care of sentinel node biopsy in cutaneous melanoma: a population‐based study in Queensland. ANZ Journal of Surgery, 93 (9), 2172-2179. doi: 10.1111/ans.18372

Trends and patterns of care of sentinel node biopsy in cutaneous melanoma: a population‐based study in Queensland

2023

Conference Publication

Surgery and radiotherapy can successfully salvage isolated lymph node field recurrence after lymphadenectomy in patients with melanoma

Henderson, Michael A., Gyorki, David, Burmeister, Bryan, Fisher, Richard, Di Julio, Juliana, Smithers, Mark, Hong, Angela, Shannon, Kerwin, Scolyer, Richard A., Carruthers, Scott, Coventry, Brendon, Babington, Scott, Duprat, Joao, Hoekstra, Harald and Thompson, John (2023). Surgery and radiotherapy can successfully salvage isolated lymph node field recurrence after lymphadenectomy in patients with melanoma. Annual International Conference of the Society-of-Surgical-Oncology (SSO) on Surgical Cancer Care, Boston, MA United States, 22-25 March 2023. New York, NY United States: Springer. doi: 10.1245/s10434-023-13332-7

Surgery and radiotherapy can successfully salvage isolated lymph node field recurrence after lymphadenectomy in patients with melanoma

2023

Journal Article

Textbook outcomes for oesophagectomy: A valid composite measure assessment tool for surgical performance in a specialist unit

Wu, Michael Yulong, McGregor, Richard J., Scott, Justin, Smithers, B. Mark, Thomas, Janine, Frankel, Adam, Barbour, Andrew and Thomson, Iain (2023). Textbook outcomes for oesophagectomy: A valid composite measure assessment tool for surgical performance in a specialist unit. European Journal of Surgical Oncology, 49 (9) 106897, 106897. doi: 10.1016/j.ejso.2023.03.233

Textbook outcomes for oesophagectomy: A valid composite measure assessment tool for surgical performance in a specialist unit

2023

Journal Article

Conditional survival in patients with stage IB‐IIIA melanoma undergoing sentinel node biopsy in Queensland: a longitudinal study

Tedman, Alexander James, Liyanage, Upekha E., Chong, Sharene, Rowe, Casey, von Schuckmann, Lena A., Malt, Maryrose, Green, Adele C., Smithers, B. Mark and Khosrotehrani, Kiarash (2023). Conditional survival in patients with stage IB‐IIIA melanoma undergoing sentinel node biopsy in Queensland: a longitudinal study. Australasian Journal of Dermatology, 64 (1), e34-e40. doi: 10.1111/ajd.13974

Conditional survival in patients with stage IB‐IIIA melanoma undergoing sentinel node biopsy in Queensland: a longitudinal study

2023

Book Chapter

Gastroesophageal reflux disease

Frankel, Adam and Smithers, B. Mark (2023). Gastroesophageal reflux disease. Mastering endo-laparoscopic and thoracoscopic surgery: ELSA manual. (pp. 219-227) edited by Davide Lomanto, William Tzu-Liang Chen and Marilou B. Fuentes. Singapore: Springer Nature Singapore. doi: 10.1007/978-981-19-3755-2_34

Gastroesophageal reflux disease

2022

Journal Article

Does Residual Invasive Disease in Wide Local Excision after Diagnosis with Partial Biopsy Technique Influence Survival in Melanoma? Matched-Pair Analysis of Multicenter Selective Lymphadenectomy Trial I and II, (vol 235, pg 49 2022)

Morton, Donald L., Faries, Mark B., Wang, He-Jing, Elashoff, Robert, Thompson, John F., Coventry, Brendon J., Smithers, B. Mark, Cochran, Alistair J., Elashoff, Robert, Wang, He-Jing, Mozzillo, Nicola, Nieweg, Omgo E., Roses, Daniel F., Hoekstra, Harald J., Karakousis, Constantine P., Kraybill, William G., Puleo, Christopher A., Kashani-Sabet, Mohammed, Paul, Eberhard and McKinnon, J. Gregory (2022). Does Residual Invasive Disease in Wide Local Excision after Diagnosis with Partial Biopsy Technique Influence Survival in Melanoma? Matched-Pair Analysis of Multicenter Selective Lymphadenectomy Trial I and II, (vol 235, pg 49 2022). Journal of the American College of Surgeons, 235 (6), 973-974. doi: 10.1097/XCS.0000000000000411

Does Residual Invasive Disease in Wide Local Excision after Diagnosis with Partial Biopsy Technique Influence Survival in Melanoma? Matched-Pair Analysis of Multicenter Selective Lymphadenectomy Trial I and II, (vol 235, pg 49 2022)

2022

Journal Article

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

2022

Journal Article

Efficacy of laparoscopic fundoplication in patients with chronic cough and gastro-oesophageal reflux

Frankel, Adam, Ong, Hock Soo, Smithers, B. Mark, Nathanson, Les K. and Gotley, David C. (2022). Efficacy of laparoscopic fundoplication in patients with chronic cough and gastro-oesophageal reflux. Esophagus, 20 (1), 1-8. doi: 10.1007/s10388-022-00953-2

Efficacy of laparoscopic fundoplication in patients with chronic cough and gastro-oesophageal reflux

2022

Journal Article

It's time we measure more than Australia's gastrectomy mortality rate

Johnson, Mary Ann, Winter, Nicole and Smithers, Mark (2022). It's time we measure more than Australia's gastrectomy mortality rate. ANZ Journal of Surgery, 92 (9), 1972-1973. doi: 10.1111/ans.17997

It's time we measure more than Australia's gastrectomy mortality rate

2022

Conference Publication

Radiomics biomarkers are associated with survival in patients with oesophageal adenocarcinoma

Aoude, L.G., Bonazzi, V.F., Brosda, S., Wong, B., Moradi, H., Lonie, J., Bradford, J., Bloxham, C., Atkinson, V.G., Law, P., Lampe, G., Smithers, M., Waddell, N., Vegh, V., Miles, K. and Barbour, A.P. (2022). Radiomics biomarkers are associated with survival in patients with oesophageal adenocarcinoma. ESMO Congress 2022, Singapore, 9 - 13 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2022.07.1357

Radiomics biomarkers are associated with survival in patients with oesophageal adenocarcinoma

2022

Journal Article

Risk factors, diagnosis and management of chyle leak following esophagectomy for cancers: an international consensus statement

Kamarajah, Sivesh K., Siddaiah-Subramanya, Manjunath, Parente, Alessandro, Evans, Richard P. T., Adeyeye, Ademola, Ainsworth, Alan, Takahashi, Alberto M. L., Charalabopoulos, Alex, Chang, Andrew, Eroglue, Atila, Wijnhoven, Bas, Donohoe, Claire, Molena, Daniela, Talavera-Urquijo, Eider, Takeda, Flavio Roberto, Darling, Gail, Rosero, German, Piessen, Guillaume, Mahendran, Hans, Kuei, Hsu Po, Gockel, Ines, Negoi, Ionut, Weindelmayer, Jacopo, Rasanen, Jari, Bekele, Kebebe, Kim, Guowei, Depypere, Lieven, Ferri, Lorenzo, Nilsson, Magnus ... Griffiths, Ewen A. (2022). Risk factors, diagnosis and management of chyle leak following esophagectomy for cancers: an international consensus statement. Annals of Surgery Open, 3 (3) e192, 1-8. doi: 10.1097/as9.0000000000000192

Risk factors, diagnosis and management of chyle leak following esophagectomy for cancers: an international consensus statement

2022

Journal Article

Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer: a modified Delphi consensus process

Chidambaram, Swathikan, Patel, Nikhil M., Sounderajah, Viknesh, Alfieri, Rita, Bonavina, Luigi, Cheong, Edward, Cockbain, Andy, D'Journo, Xavier Benoit, Ferri, Lorenzo, Griffiths, Ewen A., Grimminger, Peter, Gronnier, Caroline, Gutschow, Christian, Hedberg, Jakob, Kauppila, Joonas H., Lagarde, Sjoerd, Low, Donald, Nafteux, Philippe, Nieuwenhuijzen, Grard, Nilsson, Magnus, Rosati, Riccardo, Schroeder, Wolfgang, Smithers, B. Mark, Henegouwen, Mark I. van Berge, van Hillegesberg, Richard, Watson, David, Vohra, Ravinder, Maynard, Nick and Markar, Sheraz R. (2022). Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer: a modified Delphi consensus process. Diseases of the Esophagus, 36 (1) doac038. doi: 10.1093/dote/doac038

Identifying a core symptom set triggering radiological and endoscopic investigations for suspected recurrent esophago-gastric cancer: a modified Delphi consensus process

Supervision

Availability

Professor Mark Smithers is:
Not available for supervision

Supervision history

Current supervision

  • Master Philosophy

    Retroperitoneal sarcoma: Impact of the patterns of care on patient outcomes in Queensland.

    Principal Advisor

    Other advisors: Professor Andrew Barbour

  • Master Philosophy

    Trends in the regional nodal management of cutaneous melanoma.

    Principal Advisor

    Other advisors: Professor Peter Soyer

  • Master Philosophy

    Factors Influencing Anastomotic Complications after Oesophagectomy

    Associate Advisor

  • Doctor Philosophy

    Utilising the Multi-Disciplinary Resources at Tertiary Centres to Improve Outcomes from Pancreatic Cancer

    Associate Advisor

    Other advisors: Dr David Cavallucci

Completed supervision

Media

Enquiries

Contact Professor Mark Smithers directly for media enquiries about:

  • Advanced endoscopic surgery
  • Cancer surgery
  • Endoscopic surgery
  • General surgery
  • Melanoma
  • Surgery - cancer
  • Surgery - oesophageal, gastric cancer
  • Surgery - upper GI
  • Upper GI surgery

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