
Overview
Background
Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.
He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.
He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.
Availability
- Professor Mark Smithers is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Honorary Fellow, American Surgical Association, American Surgical Association
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
- Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England
Research interests
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Cutaneous Melanoma
epidemiology, public health issues and management of all stages
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Management of Oesophageal and Gastric Cancer
Investigation and management of benign and malignant diseases of the oesophagus and the stomach.
Works
Search Professor Mark Smithers’s works on UQ eSpace
2004
Journal Article
Use of oesophagogastroscopy to assess the response of oesophageal carcinoma to neoadjuvant therapy
Brown, WA, Thomas, J, Gotley, D, Burmeister, BH, Lim, KH, Martin, I, Walpole, ET, Thomson, DB, Harvey, JA and Smithers, BM (2004). Use of oesophagogastroscopy to assess the response of oesophageal carcinoma to neoadjuvant therapy. British Journal of Surgery, 91 (2), 199-204. doi: 10.1002/bjs.4411
2004
Book Chapter
Primary melanomas of the gastrointestinal tract
Smithers, B. M. (2004). Primary melanomas of the gastrointestinal tract. Textbook of Melanoma. (pp. 648-662) edited by J. Thompson. London, United Kingdom: Martin Dunitz.
2003
Journal Article
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients
Stowasser, Michael, Gordon, Richard D., Gunasekera, Thanuja G., Cowley, Diane C., Ward, Gregory, Archibald, Colin and Smithers, B. Mark (2003). High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. Journal of Hypertension, 21 (11), 2149-2157. doi: 10.1097/01.hjh.0000098141.70956.53
2003
Journal Article
Relapse patterns after chemo-radiation for carcinoma of the oesophagus
Denham, J. W., Steigler, A., Kilmurray, J., Wratten, C., Burmeister, B., Lamb, D. S., Joseph, D., Delaney, G., Christie, D., Jamieson, G., Smithers, B. M., Ackland, S. and Walpole, E. (2003). Relapse patterns after chemo-radiation for carcinoma of the oesophagus. Clinical Oncology, 15 (3), 98-108. doi: 10.1053/clon.2003.0212
2003
Conference Publication
A randomized controlled trial of surgery alone compared with chemoradiation and surgery: A focus on the surgical outcomes
Smithers, B. M. (2003). A randomized controlled trial of surgery alone compared with chemoradiation and surgery: A focus on the surgical outcomes. SSO 56th Annual Cancer Symposium, Los Angeles, USA, 5-9 March 2003. USA: Society of Surgical Oncology.
2003
Conference Publication
A comparison of treatment outcome between adenocarcinoma and squamous cell carcinoma of the eosophagus
Lim, K. H., Thomas, J., Brown, W. A., Harvey, J., Burmeister, B., Walpole, E., Thomson, D., Martin, I., Gotley, D. C. and Smithers, B. M. (2003). A comparison of treatment outcome between adenocarcinoma and squamous cell carcinoma of the eosophagus. -, -, -. Carlton, Victoria: Blackwell Publishing. doi: 10.1111/j.1445-2197.2003.00009.x
2003
Conference Publication
A Phase I study of paclitaxel, fluorouracil and radiation for advanced esophageal carcinoma
Thomson, D. B., Walpole, E., Burmeister, B., Burmeister, E., Harvey, J., Woodward, N., Gotley, D. and Smithers, M. (2003). A Phase I study of paclitaxel, fluorouracil and radiation for advanced esophageal carcinoma. 2003 ASCO Annual Meeting, Chicago, IL United States, 31 May - 3 June 2003.
2003
Conference Publication
A randomized controlled trial of surgery alone compared with chemoradiation & surgery: a focus on the surgical outcomes
Smithers, B. M., Burmeister, B. H., Fitzgerald, L., Gebski, V., Denham, J., Devitt, P., Ackland, S., Joseph, D., Millar, J., North, J., Walpole, E. and Gotley, D. (2003). A randomized controlled trial of surgery alone compared with chemoradiation & surgery: a focus on the surgical outcomes. 56th Annual Cancer Symposium of the Society of Surgical Oncology, Los Angeles, CA, United States, 5-9 March 2003. New York, NY, United States: Springer.
2003
Conference Publication
A randomised controlled trial of surgery alone compared with chemoradiation and surgery: A focus on surgical outcomes
Smithers, B. M. and Burmeister, B. (2003). A randomised controlled trial of surgery alone compared with chemoradiation and surgery: A focus on surgical outcomes. 56th Annual Cancer Symposium of the Society-of-Surgical-Oncology, Los Angeles, CA, 5-9 March, 2003. Hagerstown, MD: Springer. doi: 10.1245/s10434-006-8001-8
2003
Journal Article
Clinical response after intradermal immature dendritic cell vaccination in metastatic melanoma is associated with immune response to particulate antigen
Smithers, Mark, O'Connell, Kathleen, MacFadyen, Susan, Chambers, Melita, Greenwood, Kathryn, Boyce, Amanda, Abdul-Jabbar, Ibtissam, Barker, Kylie, Grimmett, Karen, Walpole, Euan and Thomas, Ranjeny (2003). Clinical response after intradermal immature dendritic cell vaccination in metastatic melanoma is associated with immune response to particulate antigen. Cancer Immunology Immunotherapy, 52 (1), 41-52. doi: 10.1007/s00262-002-0318-y
2003
Conference Publication
The role of surgery in the management of locally advanced oesophageal carcinoma
Brown, W. A., Thomas, J., Gotley, D. C., Lim, K. H., Martin, I. and Smithers, B. M. (2003). The role of surgery in the management of locally advanced oesophageal carcinoma. Annual Scientific Congress – Royal Australasian College of Surgeons, Brisbane, Qld, Australia, 2003. Carlton, Vic. Australia: Blackwells Publishing. doi: 10.1111/j.1445-2197.2003.00009.x
2003
Conference Publication
Symptomatic and functional outcome 1 year after reoperative antireflux surgery for recurrent reflux, dysphagia and gas bloat
Byrne, J. P., Menzies, B., Martin, I. J., Smithers, B. M., Nathanson, L. and Gotley, D. C. (2003). Symptomatic and functional outcome 1 year after reoperative antireflux surgery for recurrent reflux, dysphagia and gas bloat. Annual Meeting of the Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland, Dublin, Ireland, 26-27 September 2002. West Sussex, United Kingdom: John Wiley & Sons.
2003
Conference Publication
Assessing the response of eosophageal carcinoma to neoadjuvant therapy using oesophagogastroscopy
Brown, W. A., Thomas, J., Gotley, D. C., Lim, K. H., Martin, I., Burmeister, B., Harvey, J., Walpole, E., Thomson, D. and Smithers, B. M. (2003). Assessing the response of eosophageal carcinoma to neoadjuvant therapy using oesophagogastroscopy. RACS Annual Scientific Congress 2003, Brisbane, Australia, 5-9 May, 2003. Carlton, Vic.: Blackwell Publishing.. doi: 10.1046/j.1445-2197.73.s.9.x
2002
Journal Article
TEM and SEM studies of microstructural transformations of thin iron films during annealing
Lisowski, W, Keim, EG and Smithers, M (2002). TEM and SEM studies of microstructural transformations of thin iron films during annealing. Applied Surface Science, 189 (1-2) PII S0169-4332(02)00016-8, 148-156. doi: 10.1016/S0169-4332(02)00016-8
2002
Journal Article
The triad of bilateral retinoblastoma, dysplastic naevus syndrome and multiple cutaneous malignant melanomas: a case report and review of the literature
Belt, P.J., Smithers, M. and Elston, T. (2002). The triad of bilateral retinoblastoma, dysplastic naevus syndrome and multiple cutaneous malignant melanomas: a case report and review of the literature. Melanoma Research, 12 (2), 179-182. doi: 10.1097/00008390-200204000-00012
2002
Journal Article
Radiation therapy following nodal surgery for melanoma: An analysis of late toxicity
Burmeister, B. H., Smithers, B. M., Davis, S., Spry, N., Johnson, C., Krawitz, H. and Baumann, K. C. (2002). Radiation therapy following nodal surgery for melanoma: An analysis of late toxicity. Anz Journal of Surgery, 72 (5), 344-348. doi: 10.1046/j.1445-2197.2002.02405.x
2002
Journal Article
Second primary oesophageal cancer following radiation for breast cancer
Matheson, JB, Burmeister, BH, Smithers, BM, Gotley, D, Harvey, JA and Doyle, L (2002). Second primary oesophageal cancer following radiation for breast cancer. Radiotherapy And Oncology, 65 (3), 159-163. doi: 10.1016/S0167-8140(02)00135-4
2002
Conference Publication
A randomized phase III trial of preoperative chemoradiation followed by surgery (CR-S) versus surgery alone (S) for localized resectable cancer of the esophagus
Burmeister, Bryan H., Smithers, Bernard M., Fitzgerald, L., Gebski, Val, Devitt, P., Ackland, Stephen, Joseph, David, Millar, J., North, J., Walpole, Euan T. and Denham, Jim W. (2002). A randomized phase III trial of preoperative chemoradiation followed by surgery (CR-S) versus surgery alone (S) for localized resectable cancer of the esophagus. 2002 ASCO Annual Meeting, xx, 2002.
2002
Journal Article
Gastric cancer in Australia
Ong H.S. and Smithers B.M. (2002). Gastric cancer in Australia. Gastric Cancer, 5 (2), 118-121. doi: 10.1007/s101200200020
2002
Journal Article
Early reoperation for acute dysphagia following laparoscopic fundoplication
Bessell, JR, Adair, WD, Smithers, BM, Martin, I, Menzies, B and Gotley, DC (2002). Early reoperation for acute dysphagia following laparoscopic fundoplication. British Journal of Surgery, 89 (6), 783-786. doi: 10.1046/j.1365-2168.2002.02112.x
Supervision
Availability
- Professor Mark Smithers is:
- Not available for supervision
Supervision history
Current supervision
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Master Philosophy
Retroperitoneal sarcoma: Impact of the patterns of care on patient outcomes in Queensland.
Principal Advisor
Other advisors: Professor Andrew Barbour
-
Master Philosophy
Trends in the regional nodal management of cutaneous melanoma.
Principal Advisor
Other advisors: Professor Peter Soyer
-
Master Philosophy
Factors Influencing Anastomotic Complications after Oesophagectomy
Associate Advisor
-
Doctor Philosophy
Utilising the Multi-Disciplinary Resources at Tertiary Centres to Improve Outcomes from Pancreatic Cancer
Associate Advisor
Other advisors: Dr David Cavallucci
Completed supervision
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2020
Master Philosophy
An assessment of the impacts of centralising complex upper-gastrointestinal surgery in Queensland
Principal Advisor
-
2024
Master Philosophy
In vivo Magnetic Resonance Spectroscopy (MRS) with 2-Dimensional (2D) COrrelated Spectroscopy (COSY) applied to breast cancer
Associate Advisor
-
2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
Other advisors: Professor Kiarash Khosrotehrani
-
2020
Doctor Philosophy
An evaluation of the role of locoregional treatments for the management of in-transit melanoma metastases
Associate Advisor
Other advisors: Professor Peter Soyer, Associate Professor Helmut Schaider
Media
Enquiries
Contact Professor Mark Smithers directly for media enquiries about:
- Advanced endoscopic surgery
- Cancer surgery
- Endoscopic surgery
- General surgery
- Melanoma
- Surgery - cancer
- Surgery - oesophageal, gastric cancer
- Surgery - upper GI
- Upper GI surgery
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