
Overview
Background
Emeritus Professor Mark Smithers is a surgical oncologist who specialises in surgery for oesophago-gastric diseases, melanoma, advanced skin cancer and soft tissue sarcoma. He was the Director of the Upper GI and Soft Tissue Unit at the Princess Alexandra Hospital, in Brisbane, Australia from 1998 - 2023. Commencing his academic career with the University of Queensland in 1987, he progressed to be the Mayne Chair in Surgery and head of the Academy of Surgery. He is the second University of Queensland Medical graduate to be appointed to this role. His research has been focussed on the development and assessment of outcomes from minimally invasive upper GI surgery, and trials assessing the role of perioperative multidisciplinary therapy for esophageal and gastric cancer. As well he has led, or been involved with, clinical trials from phase I to III, for all stages of melanoma through his role as the Chair of the Queensland Melanoma Project. More recently he has been involved with the assessment of access to, and outcomes from, surgery for cancer in Queensland, Australia.
He has overseen the administration and development of the surgery curriculum, and the teaching, in the Academy of Surgery, in the UQ Faculty of Medicine. He was on a number of committees relevant to the implementation of the UQ MD design course. He has held various leadership and committee roles with the Royal Australasian College of Surgeons, as well as leadership roles, including the Presidency, in the Australian and New Zealand Oesophago Gastric Surgeons Association. He has also been on the committees of international organisations related to oesophageal and gastric surgery. He has published 250 articles, eight book chapters, and has been on the editorial board of a number of surgical journals.
He has been recognised for his clinical and academic roles by the award of Member of the Order of Australia (AM). The citation reads, "for service to medicine in the fields of gastro-intestinal and melanoma surgery, to medical education and to professional organisations". The Royal Australasian College of Surgeons awarded him the Sir Hugh Devine medal, for services to surgery and the community. This is the College’s highest honour. Internationally, he has been awarded an honorary fellowship of the Royal College of Surgeons of Edinburgh and recently, in the United States, he was elected as an Honarary Fellow of the American Surgical Association.
Availability
- Professor Mark Smithers is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Honorary Fellow, American Surgical Association, American Surgical Association
- Fellow, Royal Australasian College of Surgeons, Royal Australasian College of Surgeons
- Fellow, Royal College of Surgeons of Edinburgh, Royal College of Surgeons of Edinburgh
- Fellow, Royal College of Surgeons of England, Royal College of Surgeons of England
Research interests
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Cutaneous Melanoma
epidemiology, public health issues and management of all stages
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Management of Oesophageal and Gastric Cancer
Investigation and management of benign and malignant diseases of the oesophagus and the stomach.
Works
Search Professor Mark Smithers’s works on UQ eSpace
2010
Journal Article
Symptoms, investigations and management of patients with cancer of the oesophagus and gastro-oesophageal junction in Australia
Smithers, Bernard M., Fahey, Paul P., Corish, Tracie, Gotley, David C, Falk, Gregory L., Smith, Garett S., Kiroff, George K., Clouston, Andrew D., Watson, David I. and Whiteman, David C. (2010). Symptoms, investigations and management of patients with cancer of the oesophagus and gastro-oesophageal junction in Australia. Medical Journal of Australia, 193 (10), 572-577. doi: 10.5694/j.1326-5377.2010.tb04064.x
2010
Journal Article
No role for melanoma treatment in the association between melanoma and amyotrophic lateral sclerosis or Parkinson's disease
Baade, Peter D., Herrero Hernández, Elena, Freedman, D. Michal, Smithers, B. Mark and Fritschi, Lin (2010). No role for melanoma treatment in the association between melanoma and amyotrophic lateral sclerosis or Parkinson's disease. Neuroepidemiology, 35 (4), 303-304. doi: 10.1159/000321177
2010
Journal Article
Risk stratification for early esophageal adenocarcinoma: Analysis of lymphatic spread
Barbour, Andrew P., Jones, Mark, Brown, Ian, Gotley, David C., Martin, Ian, Thomas, Janine, Clouston, Andre and Smithers, B. Mark (2010). Risk stratification for early esophageal adenocarcinoma: Analysis of lymphatic spread. Annals of Surgical Oncology, 17 (9), 2494-2502. doi: 10.1245/s10434-010-1025-0
2010
Journal Article
High-risk human papillomavirus in esophageal squamous cell carcinoma
Antonsson, Annika, Nancarrow, Derek J., Brown, Ian S., Green, Adele C., Drew, Paul A., Watson, David I., Hayward, Nicholas K., Whiteman, David C., For the Australian Cancer Study, Gotley, David and Smithers, B. Mark (2010). High-risk human papillomavirus in esophageal squamous cell carcinoma. Cancer Epidemiology Biomarkers & Prevention, 19 (8), 2080-2087. doi: 10.1158/1055-9965.EPI-10-0033
2010
Journal Article
Thoracoscopic-assisted esophagectomy for esophageal cancer: Analysis of patterns and prognostic factors for recurrence
Thomson, Iain G., Smithers, Bernard M., Gotley, David C., Martin, Ian, Thomas, Janine M., O'Rourke, Peter and Barbour, Andrew P. (2010). Thoracoscopic-assisted esophagectomy for esophageal cancer: Analysis of patterns and prognostic factors for recurrence. Annals of Surgery, 252 (2), 281-291. doi: 10.1097/SLA.0b013e3181e909a2
2010
Journal Article
Minimally invasive esophagectomy: An overview
Smithers, B. Mark (2010). Minimally invasive esophagectomy: An overview. Expert Review of Gastroenterology and Hepatology, 4 (1), 91-99. doi: 10.1586/EGH.09.62
2010
Journal Article
A novel treatment for metastatic melanoma with intralesional rose bengal and radiotherapy: A case series
Foote, Matthew C., Burmeister, Bryan H., Thomas, Janine and Smithers, B. Mark (2010). A novel treatment for metastatic melanoma with intralesional rose bengal and radiotherapy: A case series. Melanoma Research, 20 (1), 48-51. doi: 10.1097/CMR.0b013e328331caa2
2010
Conference Publication
Chemoablation of metastatic melanoma with rose bengal (PV-10)
Agarwala, S. S., Thompson, J. F., Smithers, B. M., Rose, M. I., Coventry, B. J., Minor, D. R., Scoggins, C. R. and Wachter, E. A. (2010). Chemoablation of metastatic melanoma with rose bengal (PV-10). Melanoma 2010 Congress, Sydney, Australia, 4-7 November 2010. Alexandria, VA, United States: American Society of Clinical Oncology .
2009
Journal Article
Isolated limb infusion for malignant melanoma: Predictors of response and outcome
Barbour, A. P., Thomas, J., Suffolk, J., Beller, E. and Smithers, B. M, (2009). Isolated limb infusion for malignant melanoma: Predictors of response and outcome. Annals of Surgical Oncology, 16 (12), 3463-3472. doi: 10.1245/s10434-009-0717-9
2009
Journal Article
Prognostic value maximum standardized uptake value from preoperative positron emission tomography in resectable adenocarcinoma of the esophagus treated by surgery alone
Shenfine, J., Barbour, A. P., Wong, D., Martin, I., Gotley, D. C. and Smithers, B. M. (2009). Prognostic value maximum standardized uptake value from preoperative positron emission tomography in resectable adenocarcinoma of the esophagus treated by surgery alone. Diseases of the Esophagus, 22 (8), 668-675. doi: 10.1111/j.1442-2050.2009.00941.x
2009
Conference Publication
Successful management of an aortoesophageal fistula caused by a fish bone - Case report and review of literature
Kelly, Stephen L., Peters, Paul, Ogg, Murray J., Li, Alan and Smithers, Bernard M. (2009). Successful management of an aortoesophageal fistula caused by a fish bone - Case report and review of literature. Conjoint Annual Scientific Congress of the Royal Australian College of Surgeons/College of Surgeons of Hong Kong, Hong Kong, Peoples Republic of China, May 2008. London, United Kingdom: BioMed Central. doi: 10.1186/1749-8090-4-21
2009
Journal Article
Salvage definitive chemo-radiotherapy for locally recurrent oesophageal carcinoma after primary surgery: Retrospective review
Baxi, S.H., Burmeister, B., Harvey, J., Smithers, B.M. and Thomas, J. (2009). Salvage definitive chemo-radiotherapy for locally recurrent oesophageal carcinoma after primary surgery: Retrospective review. Journal of Medical Imaging and Radiation Oncology, 52 (6), 583-587. doi: 10.1111/j.1440-1673.2008.02023.x
2009
Conference Publication
Adjuvant Radiotherapy Improves Regional (Lymph Node Field) Control in Melanoma Patients after Lymphadenectomy: Results of an Intergroup Randomized Trial (TROG 02.01/ANZMTG 01.02)
Burmeister, B., Henderson, M., Thompson, J., Fisher, R., Di Iulio, J., Smithers, M., Hong, A., Carruthers, S., Hoekstra, H. and Ainslie, J. (2009). Adjuvant Radiotherapy Improves Regional (Lymph Node Field) Control in Melanoma Patients after Lymphadenectomy: Results of an Intergroup Randomized Trial (TROG 02.01/ANZMTG 01.02). 51st Annual Meeting of the American-Society-for-Radiation-Oncology, Chicago, IL, 1-5 November 2009. United States: Elsevier. doi: 10.1016/j.ijrobp.2009.07.031
2009
Journal Article
A phase II trial of chemoradiation therapy with weekly oxaliplatin and protracted infusion of 5-fluorouracil for esophageal cancer
Burmeister, B., Walpole, E., D'Arcy, N., Burmeister, E.A., Cox, S., Thomson, D.B., Harvey, J. and Smithers, B.M. (2009). A phase II trial of chemoradiation therapy with weekly oxaliplatin and protracted infusion of 5-fluorouracil for esophageal cancer. Investigational New Drugs, 27 (3), 275-279. doi: 10.1007/s10637-008-9178-4
2009
Conference Publication
Chemoablation of melanoma with intralesional rose bengal (PV-10)
Agarwala, S. S., Thompson, J., Smithers, M., Ross, M., Coventry, B., Minor, D., Scoggins, C., Hersey, P. and Wachter, E. (2009). Chemoablation of melanoma with intralesional rose bengal (PV-10). 45th Annual Meeting of the American Society of Clinical Oncology, Orlando, FL, U.S.A., 29 May - 2 June 2009. Alexandria, VA, U.S.A.: American Society of Clinical Oncology.
2008
Journal Article
Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma
Smith, Eric, De Young, Neville J., Pavey, Sandra J., Hayward, Nicholas K., Nancarrow, Derek J., Whiteman, David C., Smithers, B. Mark, Ruszkiewicz, Andrew R., Clouston, Andrew D., Gotley, David C., Devitt, Peter G., Jamieson, Glyn G. and Drew, Paul A. (2008). Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma. Molecular Cancer, 7 (1) 75, 75.1-75.12. doi: 10.1186/1476-4598-7-75
2008
Journal Article
Refining esophageal cancer staging after neoadjuvant therapy: importance of treatment response
Barbour, A.P., Jones, M., Gonen, M., Gotley, D.C., Thomas, J., Thomson, D.B., Burmeister, B. and Smithers, B.M. (2008). Refining esophageal cancer staging after neoadjuvant therapy: importance of treatment response. Annals of Surgical Oncology, 15 (10), 2894-2902. doi: 10.1245/s10434-008-0084-y
2008
Journal Article
Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays
Nancarrow, D.J., Handoko, H. Y., Smithers, B.M., Gotley, D. C., Drew, P.A., Watson, D.I., Clouston, A. D., Hayward, N. and Whiteman, D. C. (2008). Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays. Cancer Research, 68 (11), 4163-4172. doi: 10.1158/0008-5472.CAN-07-6710
2008
Journal Article
Consideration of mesh-related complications: Letters and comments
Shenfine, Jon, Barbour, Andrew, Martin, Ian, Smithers, B. Mark and Gotley, David C. (2008). Consideration of mesh-related complications: Letters and comments. Annals of the Royal College of Surgeons of England, 90 (2), 175-176. doi: 10.1308/003588408X261780
2008
Journal Article
Re: Comparison of the outcomes between open and minimally invasive esophagectomy - Reply
Smithers, Bernard M. and Gotley, David (2008). Re: Comparison of the outcomes between open and minimally invasive esophagectomy - Reply. Annals of Surgery, 247 (2), 397-398. doi: 10.1097/SLA.0b013e3181640266
Supervision
Availability
- Professor Mark Smithers is:
- Not available for supervision
Supervision history
Current supervision
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Master Philosophy
Trends in the regional nodal management of cutaneous melanoma.
Principal Advisor
Other advisors: Professor Peter Soyer
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Master Philosophy
Retroperitoneal sarcoma: Impact of the patterns of care on patient outcomes in Queensland.
Principal Advisor
Other advisors: Professor Andrew Barbour
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Master Philosophy
Factors Influencing Anastomotic Complications after Oesophagectomy
Associate Advisor
-
Doctor Philosophy
Utilising the Multi-Disciplinary Resources at Tertiary Centres to Improve Outcomes from Pancreatic Cancer
Associate Advisor
Other advisors: Dr David Cavallucci
Completed supervision
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2020
Master Philosophy
An assessment of the impacts of centralising complex upper-gastrointestinal surgery in Queensland
Principal Advisor
-
2024
Master Philosophy
In vivo Magnetic Resonance Spectroscopy (MRS) with 2-Dimensional (2D) COrrelated Spectroscopy (COSY) applied to breast cancer
Associate Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
Other advisors: Professor Kiarash Khosrotehrani
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2020
Doctor Philosophy
An evaluation of the role of locoregional treatments for the management of in-transit melanoma metastases
Associate Advisor
Other advisors: Professor Peter Soyer, Associate Professor Helmut Schaider
Media
Enquiries
Contact Professor Mark Smithers directly for media enquiries about:
- Advanced endoscopic surgery
- Cancer surgery
- Endoscopic surgery
- General surgery
- Melanoma
- Surgery - cancer
- Surgery - oesophageal, gastric cancer
- Surgery - upper GI
- Upper GI surgery
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