Overview
Background
- Director, Herston Imaging Research Facility
- Professorial Research Fellow and Senior Group Leader, AIBN
- Nuclear Medicine Specialist, Dept Nuclear Medicine & PET Services, Royal Brisbane & Women’s Hospital
Ros Francis is an academic Nuclear Medicine specialist who has established an innovative and highly collaborative research career focused on clinical trials, novel radiopharmaceuticals for imaging and therapy, and innovative approaches for quantitative imaging. Her expertise spans diverse fields including oncology, cardiology, neurology and inflammatory diseases, with a focus on research translation. Ros is passionate about nuclear medicine clinical trials and has been integral in the establishment of Australasian Radiopharmaceutical Trials Network (ARTnet), for which she has been Scientific Chair since 2014.
Ros relocated to Brisbane in 2024 from Western Australia and is enjoying new opportunities in Queensland’s vibrant and innovative biodiscovery ecosystem. As Director of Herston Imaging Research Facility and Senior Group Leader AIBN, Ros aims to lead translational research to improve outcomes for patients
Availability
- Professor Roslyn Francis is:
- Available for supervision
Research impacts
Ros is an academic Nuclear Medicine Specialist and combines clinical practice with an active and impactful research career. After graduating from University of Western Australia in 1994 she held a Cancer Research UK Clinical Research Fellowship for 4 years, undertaking a PhD at the Royal Free Hospital London on antibody therapies. Following relocation back to Australia in 2003, Ros completed Australian requirements for physician training and specialisation in Nuclear Medicine. Ros has held positions in Western Australia as Nuclear Medicine Specialist at Sir Charles Gairdner Hospital from 2007 (Head of Department 2013-2023) and an academic appointment at UWA from 2010 as A/Prof Molecular Imaging, UWA Medical School. In 2024, Ros commenced in Brisbane as Nuclear Medicine Specialist at the Royal Brisbane and Women’s Hospital, Professor and Group Leader UQ-AIBN and Director Herston Imaging Research Facility.
Ros has a research portfolio encompassing discovery research to clinical trials with radiopharmaceuticals for imaging or therapy (theranostics). Her research has spanned preclinical and human imaging, with a strong focus on image quality and quantitation. Ros is chief investigator on competitive research grants > $36million in the last 10 years, including NHMRC CRE, MRFF clinical trials and ACRF infrastructure grants. In Queensland, Ros is leading an $1.8 million MRFF grant investigating a new radio-imaging agent to guide targeted therapy for epithelial ovarian cancer. Ros has 95 publications, 52 the last 5 years, including in leading journals Lancet x2, Lancet Oncol x4 and J Nucl Med x 5 (h index 31, >5000 citations).
Ros has been inaugural Scientific Chair of Australasian Radiopharmaceutical Trials network (ARTnet) since 2014. ARTnet has facilitated internationally impactful multicentre clinical trials in Australia, leading to high citation publications (Lancet 2020; Lancet 2021), social media and public interest, government/policy impact (Medicare recommendations) and incorporation into international practice guidelines. The ProPSMA trial, the first co-badged ARTnet/ANZUP study, was awarded the Australian Clinical Trials Alliance Trial of the Year in 2021. ARTnet has also established quality programs including PET camera accreditation, and radiopharmaceutical production standards which are critical for imaging validity in multicentre trials.
Ros has made a significant professional contribution to Nuclear Medicine in Australia. She is past President of Australian and New Zealand Society of Nuclear Medicine (ANZSNM), and is actively engaged with National Imaging Facility, including leading activity streams in the human molecular imaging translational network. She has participated in government/advisory roles including WA Radiological Council, MSAC radiopharmaceuticals working group committee, MSAC review subcommittee (Oncology) and ANSTO clinical advisory committee. Her strong international standing in clinical trials with radiopharmaceuticals is highlighted by invited presentations to EORTC imaging group, and participation in international working groups to enhance research facilitation. She has been an invited speaker at multiple national and international scientific meetings, including plenary sessions. She is a previous co-convenor of ANZSNM annual scientific meeting.
Ros values mentorship and supervision. She has supervised 4 PhD students to completion and is currently supervising 4 PhD students. She has provided clinical mentorship for Nuclear Medicine advanced trainees for over 15 years and provides mentorship for early career researchers. She has undertaken career engagement activities including clinician academic career events (Academy of Health and Medical Sciences) and as invited speaker for International Women’s Day.
Works
Search Professor Roslyn Francis’s works on UQ eSpace
2017
Conference Publication
Clinical management intent of Ga68 PSMA PET/CT imaging in prostate cancer: an Australian multicentre study
Roach, Paul, Francis, Roslyn, Emmett, Louise, McCarthy, Michael and Scott, Andrew (2017). Clinical management intent of Ga68 PSMA PET/CT imaging in prostate cancer: an Australian multicentre study. Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), Denver, CO United States, 10-14 June 2017. Reston, VA United States: Society of Nuclear Medicine.
2017
Conference Publication
ATYPICAL FOR PROSTATE METASTASIS
Culleton, S. and Francis, R. (2017). ATYPICAL FOR PROSTATE METASTASIS. HOBOKEN: WILEY.
2017
Conference Publication
A RARE CASE OF MERKEL CELL CARCINOMA CARDIAC METASTASIS CAUSING CARDIAC TAMPONADE: REVIEW OF THE ROLE OF FDG PET IN MERKEL CELL CARCINOMA
Di Loreto, M., Millward, M. and Francis, R. (2017). A RARE CASE OF MERKEL CELL CARCINOMA CARDIAC METASTASIS CAUSING CARDIAC TAMPONADE: REVIEW OF THE ROLE OF FDG PET IN MERKEL CELL CARCINOMA. HOBOKEN: WILEY.
2017
Journal Article
Is FCH PET able to identify foci of infection superiorly to FDG PET?
Hardy, Liesel Elisabeth, Hessamodini, Hannah, Wallace, Michael and Francis, Roslyn (2017). Is FCH PET able to identify foci of infection superiorly to FDG PET?. BMJ Case Reports, 2017 bcr-2017-219944, 1-1. doi: 10.1136/bcr-2017-219944
2016
Journal Article
A pilot study of the utility of choline PET-CT in prostate cancer biochemical relapse following radical prostatectomy
Tan, Hendrick, Joseph, David, Loh, Nelson K., McCarthy, Michael, Leong, Eugene, Siew, Teck, Segard, Tatiana, Morandeau, Laurence, Trevenen, Michelle and Francis, Roslyn J. (2016). A pilot study of the utility of choline PET-CT in prostate cancer biochemical relapse following radical prostatectomy. Journal of Medical Imaging and Radiation Oncology, 60 (3), 374-381. doi: 10.1111/1754-9485.12455
2015
Journal Article
A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma
Nowak, A. K., Cook, A. M., McDonnell, A. M., Millward, M. J., Creaney, J., Francis, R. J., Hasani, A., Segal, A., Musk, A. W., Turlach, B. A., McCoy, M. J., Robinson, B. W.S. and Lake, R. A. (2015). A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma. Annals of Oncology, 26 (12), 2483-2490. doi: 10.1093/annonc/mdv387
2015
Journal Article
Characterization of hypoxia in malignant pleural mesothelioma with FMISO PET-CT
Francis, Roslyn J., Segard, Tatiana, Morandeau, Laurence, Lee, Y.C. Gary, Millward, Michael J., Segal, Amanda and Nowak, Anna K. (2015). Characterization of hypoxia in malignant pleural mesothelioma with FMISO PET-CT. Lung Cancer, 90 (1), 55-60. doi: 10.1016/j.lungcan.2015.07.015
2015
Journal Article
A multicentre comparison of quantitative 90Y PET/CT for dosimetric purposes after radioembolization with resin microspheres: The QUEST Phantom Study
Willowson, Kathy P., Tapner, Michael, The QUEST Investigator Team, , Bailey, Dale L., Willowson, K. P., Tapner, M. J., Ahmadzadehfar, H., Amthauer, H., Großer, O. S., Arbizu, J., Martí-Climent, J. M., Rodriguez-Fraile, M., Attarwala, A. A., Glatting, G., Molina-Duran, F., Bagni, O., Filippi, L., Benard, F., Celler, A., Bonutti, F., Botta, F., Ferrari, M., Boucek, J. A., Francis, R., Bourgeois, A. C., Bradley, Y. C., Pasciak, A. S., Buchholz, H. G., Miederer, M. ... Yu, N. (2015). A multicentre comparison of quantitative 90Y PET/CT for dosimetric purposes after radioembolization with resin microspheres: The QUEST Phantom Study. European Journal of Nuclear Medicine and Molecular Imaging, 42 (8), 1202-1222. doi: 10.1007/s00259-015-3059-9
2014
Conference Publication
Characterization of the effect of pleurodesis on FLT and FDG PET/CT imaging in malignant pleural mesothelioma (MPM)
Francis, Roslyn, Nowak, Anna, Segard, Tatiana, Morandeau, Laurence, Lee, Gary, Boucek, Jan and Millward, Michael (2014). Characterization of the effect of pleurodesis on FLT and FDG PET/CT imaging in malignant pleural mesothelioma (MPM). Annual Meeting of the Society-of-Nuclear-Medicine-and-Molecular-Imaging (SNMMI), St Louis Mo, Jun 07-11, 2014. RESTON: SOC NUCLEAR MEDICINE INC.
2014
Journal Article
Observer variability in mesothelioma tumor thickness measurements: Defining minimally measurable lesions
Armato III, Samuel G., Nowak, Anna K., Francis, Roslyn J., Kocherginsky, Masha and Byrne, Michael J. (2014). Observer variability in mesothelioma tumor thickness measurements: Defining minimally measurable lesions. Journal of Thoracic Oncology, 9 (8), 1187-1194. doi: 10.1097/JTO.0000000000000211
2014
Journal Article
A Gelatin liver phantom of suspended 90Y resin microspheres to simulate the physiologic microsphere biodistribution of a postradioembolization liver
Kao, Yung Hsiang, Luddington, Oliver S., Culleton, Simone R., Francis, Roslyn J. and Boucek, Jan A. (2014). A Gelatin liver phantom of suspended 90Y resin microspheres to simulate the physiologic microsphere biodistribution of a postradioembolization liver. Journal of Nuclear Medicine Technology, 42 (4), 265-268. doi: 10.2967/jnmt.114.145292
2014
Journal Article
Interventional therapies for malignant pleural effusions: The present and the future
Thomas, Rajesh, Francis, Roslyn, Davies, Helen E. and Gary Lee, Y. C. (2014). Interventional therapies for malignant pleural effusions: The present and the future. Respirology, 19 (6), 809-822. doi: 10.1111/resp.12328
2013
Journal Article
Mycobacterium mimicking metastatic melanoma
Teh, R. W., Feeney, K., Francis, R. J., Phillips, M. and Millward, M. J. (2013). Mycobacterium mimicking metastatic melanoma. Internal Medicine Journal, 43 (12), 1342-1346. doi: 10.1111/imj.12209
2013
Journal Article
Post-radioembolization yttrium-90 PET/CT-part 2: Dose-response and tumor predictive dosimetry for resin microspheres
Kao, Yung-Hsiang, Steinberg, Jeffrey D., Tay, Young-Soon, Lim, Gabriel K. Y., Yan, Jianhua, Townsend, David W., Budgeon, Charley, Boucek, Jan A., Francis, Roslyn J., Cheo, Timothy S. T., Burgmans, Mark C., Irani, Farah G., Lo, Richard H. G., Tay, Kiang-Hiong, Tan, Bien-Soo, Chow, Pierce K. H., Satchithanantham, Somanesan, Tan, Andrew E. H., Ng, David C. E. and Goh, Anthony S. W. (2013). Post-radioembolization yttrium-90 PET/CT-part 2: Dose-response and tumor predictive dosimetry for resin microspheres. EJNMMI Research, 3 (1), 1-27. doi: 10.1186/2191-219X-3-57
2013
Journal Article
Detection of hypoxia with 18F-fluoromisonidazole ( 18F-FMISO) PET/CT in suspected or proven pancreatic cancer
Segard, Tatiana, Robins, Peter D., Yusoff, Ian F., Ee, Hooi, Morandeau, Laurence, Campbell, Elaine M. and Francis, Roslyn J. (2013). Detection of hypoxia with 18F-fluoromisonidazole ( 18F-FMISO) PET/CT in suspected or proven pancreatic cancer. Clinical Nuclear Medicine, 38 (1), 1-6. doi: 10.1097/RLU.0b013e3182708777
2012
Journal Article
A phase ii study of intermittent sunitinib malate as second-line therapy in progressive malignant pleural mesothelioma
Nowak, Anna K., Millward, Michael J., Creaney, Jenette, Francis, Roslyn J., Dick, Ian M., Hasani, Arman, Van Der Schaaf, Agatha, Segal, Amanda, Musk, Arthur W. and Byrne, Michael J. (2012). A phase ii study of intermittent sunitinib malate as second-line therapy in progressive malignant pleural mesothelioma. Journal of Thoracic Oncology, 7 (9), 1449-1456. doi: 10.1097/JTO.0b013e31825f22ee
2011
Journal Article
A snapshot of research activities at the WA PET service
Francis, Roslyn, Segard, Tatiana, Maton, Penny and Campbell, Elaine (2011). A snapshot of research activities at the WA PET service. Gamma Gazette, 1 (4), 24-25.
2011
Journal Article
Multimodality imaging review of malignant pleural mesothelioma diagnosis and staging
Gerbaudo, Victor H., Katz, Sharyn I., Nowak, Anna K. and Francis, Roslyn J. (2011). Multimodality imaging review of malignant pleural mesothelioma diagnosis and staging. PET Clinics, 6 (3), 275-297. doi: 10.1016/j.cpet.2011.04.001
2011
Journal Article
A multimodality imaging review of malignant pleural mesothelioma response assessment
Nowak, Anna K., Francis, Roslyn J., Katz, Sharyn I. and Gerbaudo, Victor H. (2011). A multimodality imaging review of malignant pleural mesothelioma response assessment. PET Clinics, 6 (3), 299-311. doi: 10.1016/j.cpet.2011.04.002
2011
Conference Publication
CHARACTERISATION AND PROGNOSTIC SIGNIFICANCE OF GLOBAL AND REGIONAL HYPOXIA IN MESOTHELIOMA USING 18F-MISO PET/CT IMAGING
Segard, Tatiana M. L., Nowak, Anna K., Lee, Y. C. Gary, Millward, Michael, Morandeau, Laurence M. J. A., Campbell, Elaine M. and Francis, Roslyn J. (2011). CHARACTERISATION AND PROGNOSTIC SIGNIFICANCE OF GLOBAL AND REGIONAL HYPOXIA IN MESOTHELIOMA USING 18F-MISO PET/CT IMAGING. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Funding
Current funding
Supervision
Availability
- Professor Roslyn Francis is:
- Available for supervision
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Media
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