Overview
Background
Scaling-up fermentation processes is not straightforward due to the emergence of concentration gradients at scale. For gas fermentation processes, with CO2, CO and CH4 and H2, scaling is even more challenging as high mass transfer rates need to be obtained. In his work, Lars is developing a framework to reliably scale-up gas fermentation processes, considering both mass transfer and concentration gradients. We aim to employ mechanistic models, combined with wet-lab data, to develop relationships and fluid dynamic (CFD) models to estimate the fermentation performance at industrial scale. He specialised in topics like bioreactor and bioprocess design, bioprocess scale-up/scale-down, mass transfer and transport phenomena, metabolic and kinetic modelling and simulation techniques.
Availability
- Dr Lars Puiman is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Biochemical Engineering, Delft University of Technology
- Masters (Extended) of Innovation and Technology Management, Delft University of Technology
- Masters (Extended) of Biochemical Engineering, Delft University of Technology
- Doctor of Philosophy of Bioprocess Engineering, Delft University of Technology
Works
Search Professor Lars Puiman’s works on UQ eSpace
2024
Journal Article
Understanding microbial syngas fermentation rates
Kerkhof, Iris, Puiman, Lars and Straathof, Adrie J. J. (2024). Understanding microbial syngas fermentation rates. Applied Microbiology and Biotechnology, 108 (1) 540, 1-15. doi: 10.1007/s00253-024-13364-3
2024
Journal Article
Unsupervised Learning Bioreactor Regimes
Laborda, Víctor Puig I., Puiman, Lars, Groves, Teddy, Haringa, Cees and Nielsen, Lars Keld (2024). Unsupervised Learning Bioreactor Regimes. Computers & Chemical Engineering, 194 108891, 1-17. doi: 10.1016/j.compchemeng.2024.108891
2024
Journal Article
High-resolution computation predicts that low dissolved CO concentrations and CO gradients promote ethanol production at industrial-scale gas fermentation
Puiman, Lars, Almeida Benalcázar, Eduardo, Picioreanu, Cristian, Noorman, Henk J. and Haringa, Cees (2024). High-resolution computation predicts that low dissolved CO concentrations and CO gradients promote ethanol production at industrial-scale gas fermentation. Biochemical Engineering Journal, 207 109330, 109330-207. doi: 10.1016/j.bej.2024.109330
2024
Journal Article
Bubbles and Broth: a review on the impact of broth composition on bubble column bioreactor hydrodynamics
Volger, R., Puiman, L. and Haringa, C. (2024). Bubbles and Broth: a review on the impact of broth composition on bubble column bioreactor hydrodynamics. Biochemical Engineering Journal, 201 109124, 1-12. doi: 10.1016/j.bej.2023.109124
2023
Journal Article
Downscaling industrial-scale syngas fermentation to simulate frequent and irregular dissolved gas concentration shocks
Puiman, Lars, Almeida Benalcázar, Eduardo, Picioreanu, Cristian, Noorman, Henk J. and Haringa, Cees (2023). Downscaling industrial-scale syngas fermentation to simulate frequent and irregular dissolved gas concentration shocks. Bioengineering, 10 (5) 518, 1-22. doi: 10.3390/bioengineering10050518
2022
Journal Article
Alleviating mass transfer limitations in industrial external-loop syngas-to-ethanol fermentation
Puiman, Lars, Abrahamson, Britt, van der Lans, Rob G. J. M., Haringa, Cees, Noorman, Henk J. and Picioreanu, Cristian (2022). Alleviating mass transfer limitations in industrial external-loop syngas-to-ethanol fermentation. Chemical Engineering Science, 259 117770. doi: 10.1016/j.ces.2022.117770
2022
Journal Article
Gas mass transfer in syngas fermentation broths is enhanced by ethanol
Puiman, Lars, Elisiário, Marina P., Crasborn, Lilo M. L., Wagenaar, Liselot E. C. H., Straathof, Adrie J. J. and Haringa, Cees (2022). Gas mass transfer in syngas fermentation broths is enhanced by ethanol. Biochemical Engineering Journal, 185 108505. doi: 10.1016/j.bej.2022.108505
Supervision
Availability
- Dr Lars Puiman is:
- Available for supervision
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Media
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