Dr Jobichen Chacko
Dr

Jobichen Chacko

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Background

Jobichen Chacko is a structural biologist with extensive experience in protein structural biology, protein-ligand interaction, proteases and drug discovery. He completed his PhD from National University of Singapore in the area of structural and functional studies on bacterial protein secretion system. He is proficient in the areas of Cryo-Electron microscopy (Single Particle Analysis), protein structure analysis and X-ray crystallography. He has published more than 49 research articles in high level journals and has more than 850 citations. His research interests are in host-pathogen interaction, Antiphage defense, Toll-like receptor proteins, protein secretion system, snake venom toxins and proteases. Jobichen is a member of the editorial advisory board for FEBS-openbio journal and serves as a reviewer for various scientific journals.

Availability

Dr Jobichen Chacko is:
Available for supervision

Qualifications

  • Doctor of Philosophy of Biological Sciences, National University of Singapore

Search Professor Jobichen Chacko’s works on UQ eSpace

51 works between 2006 and 2026
All (51) Journal Article (47) Other Outputs (2) Book Chapter (2)

41 - 51 of 51 works

2014

Journal Article

Dimerization of VirD2 binding protein is essential for Agrobacterium induced tumor formation in plants

Padavannil, Abhilash, Jobichen, Chacko, Yang Qinghua,, Seetharaman, Jayaraman, Velazquez-Campoy, Adrian, Yang, Liu, Pan, Shen Q. and Sivaraman, J. (2014). Dimerization of VirD2 binding protein is essential for Agrobacterium induced tumor formation in plants. PLoS Pathogens, 10 (3) e1003948, 1-12. doi: 10.1371/journal.ppat.1003948

Dimerization of VirD2 binding protein is essential for Agrobacterium induced tumor formation in plants

2013

Journal Article

Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes

Padavannil, Abhilash, Jobichen, Chacko, Mills, Erez, Velazquez-Campoy, Adrian, Li, Mo, Leung, Ka Yin, Mok, Yu Keung, Rosenshine, Ilan and Sivaraman, J. (2013). Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes. Nature Communications, 4 2546, 1-10. doi: 10.1038/ncomms3546

Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes

2013

Journal Article

Computer aided design of FtsZ targeting oligopeptides

Pieraccini, Stefano, Rendine, Stefano, Jobichen, Chacko, Domadia, Prerna, Sivaraman, J., Francescato, Pierangelo, Speranza, Giovanna and Sironi, Maurizio (2013). Computer aided design of FtsZ targeting oligopeptides. RSC Advances, 3 (6), 1739-1743. doi: 10.1039/c2ra21886k

Computer aided design of FtsZ targeting oligopeptides

2012

Journal Article

Crystal structure of mouse RhoA:GTPcS complex in a centered lattice

Jobichen, Chacko, Pal, Kuntal and Swaminathan, Kunchithapadam (2012). Crystal structure of mouse RhoA:GTPcS complex in a centered lattice. Journal of Structural and Functional Genomics, 13 (4), 241-245. doi: 10.1007/s10969-012-9143-5

Crystal structure of mouse RhoA:GTPcS complex in a centered lattice

2012

Journal Article

Identification and structural characterization of a new three-finger toxin Hemachatoxin from Hemachatus haemachatus venom

Girish, Vallerinteavide Mavelli, Kumar, Sundramurthy, Joseph, Lissa, Jobichen, Chacko, Kini, R. Manjunatha and Sivaraman, J. (2012). Identification and structural characterization of a new three-finger toxin Hemachatoxin from Hemachatus haemachatus venom. PLoS One, 7 (10) e48112, 1-9. doi: 10.1371/journal.pone.0048112

Identification and structural characterization of a new three-finger toxin Hemachatoxin from Hemachatus haemachatus venom

2012

Journal Article

Crystal structure of Der f 7, a dust mite allergen from Dermatophagoides farinae

Tan, Kang Wei, Jobichen, Chacko, Ong, Tan Ching, Gao, Yun Feng, Tiong, Yuen Sung, Wong, Kang Ning, Chew, Fook Tim, Sivaraman, J. and Mok, Yu Keung (2012). Crystal structure of Der f 7, a dust mite allergen from Dermatophagoides farinae. PLoS One, 7 (9) e44850, 1-8. doi: 10.1371/journal.pone.0044850

Crystal structure of Der f 7, a dust mite allergen from Dermatophagoides farinae

2010

Journal Article

Structural basis for the secretion of EvpC: A key type VI secretion system protein from Edwardsiella tarda

Jobichen, Chacko, Chakraborty, Smarajit, Li, Mo, Zheng, Jun, Joseph, Lissa, Mok, Yu-Keung, Leung, Ka Yin and Sivaraman, J. (2010). Structural basis for the secretion of EvpC: A key type VI secretion system protein from Edwardsiella tarda. PLoS One, 5 (9) e12910, 1-10. doi: 10.1371/journal.pone.0012910

Structural basis for the secretion of EvpC: A key type VI secretion system protein from Edwardsiella tarda

2009

Journal Article

Identification and characterization of the lipid-binding property of GrIR, a locus of enterocyte effacement regulator

Jobichen, Chacko, Fernandis, Aaron Z., Velazquez-Campoy, Adrian, Leung, Ka Yin, Mok, Yu-Keung, Wenk, Markus R. and Sivaraman, J. (2009). Identification and characterization of the lipid-binding property of GrIR, a locus of enterocyte effacement regulator. Biochemical Journal, 420 (2), 191-199. doi: 10.1042/BJ20081588

Identification and characterization of the lipid-binding property of GrIR, a locus of enterocyte effacement regulator

2007

Journal Article

Crystallization and preliminary X-ray diffraction analysis of hemextin A: a unique anticoagulant protein from Hemachatus haemachatus venom

Banerjee, Yajnavalka, Kumar, Sundramurthy, Jobichen, Chacko and Kini, R. Manjunatha (2007). Crystallization and preliminary X-ray diffraction analysis of hemextin A: a unique anticoagulant protein from Hemachatus haemachatus venom. Acta Crystallographica Section F-Structural Biology Communications, 63 (8), 701-703. doi: 10.1107/S1744309107034239

Crystallization and preliminary X-ray diffraction analysis of hemextin A: a unique anticoagulant protein from Hemachatus haemachatus venom

2007

Journal Article

Structure of GrIR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC

Jobichen, Chacko, Li, Mo, Yerushalmi, Gal, Tan, Yih Wan, Mok, Yu-Keung, Rosenshine, Ilan, Leung, Ka Yin and Sivaraman, J. (2007). Structure of GrIR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC. PLoS Pathogens, 3 (5) e69, 639-646. doi: 10.1371/journal.ppat.0030069

Structure of GrIR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC

2006

Journal Article

Biological characteristics of certain Diamondback moth ecotypes

Mohapatra, Purusottam, Chacko, Jobichen and Narayanasamy, P. (2006). Biological characteristics of certain Diamondback moth ecotypes. Journal of Entomology, 3 (4), 277-280. doi: 10.3923/je.2006.277.280

Biological characteristics of certain Diamondback moth ecotypes

Past funding

  • 2025
    Macromolecular crystallography on proteins involved in infection and innate immunity in bacterial, fungal, plants and mammalian systems
    Australian Nuclear Science and Technology Organisation
    Open grant

Availability

Dr Jobichen Chacko is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Structural basis of plant immune receptor signaling

    Associate Advisor

    Other advisors: Dr Natsumi Maruta, Professor Bostjan Kobe

  • Doctor Philosophy

    Structural and functional characterisation of TIR domain-containing proteins

    Associate Advisor

    Other advisors: Professor Bostjan Kobe

  • Doctor Philosophy

    Structural and functional analysis of bat MyD88

    Associate Advisor

    Other advisors: Professor Bostjan Kobe

Enquiries

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