Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2026
Journal Article
Text message incentives increased patient-reported outcomes survey response in emergency care: SWAT findings
Altinger, Gemma, Sharma, Sweekriti, Li, Qiang, Devaux, Anthony, Darby, Samantha, van Wyk, Aidan, Jones, Caitlin M.P., Maher, Chris G., Traeger, Adrian C., Cullen, Louise, McCaffery, Kirsten, Linder, Jeffrey A., Buchbinder, Rachelle, Harris, Ian A., Coiera, Enrico, Howard, Kirsten, Coggins, Andrew, Middleton, Paul M., Devaux, Anthony, Gunja, Naren, Ferguson, Ian, Chan, Trevor, Tambree, Karen, van Wyk, Aidan, Mallows, James, Pile, Kevin, Cracknell, Richard, Hermiz, Arsalan, Lawrence, Jeremy ... Gloss, Kayla (2026). Text message incentives increased patient-reported outcomes survey response in emergency care: SWAT findings. Journal of Clinical Epidemiology, 191 112116, 112116-191. doi: 10.1016/j.jclinepi.2025.112116
2026
Journal Article
Modifiers of the effectiveness of point-of-care troponin testing and determinants of concordance between diagnostic pathway recommendations and disposition in patients with chest pain: a post hoc analysis of a randomised controlled trial
Thulin, Viola IL, Myrmel, Gard Mikael Sæle, Jordalen, Silje Marie Farestveit, Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole-Thomas, Body, Richard, Collinson, Paul O, Apple, Fred, Cullen, Louise, Norekvål, Tone Merete, Wisløff, Torbjørn, Vikenes, Kjell, Bjørneklett, Rune Oskar, Omland, Torbjørn and Aakre, Kristin Moberg (2026). Modifiers of the effectiveness of point-of-care troponin testing and determinants of concordance between diagnostic pathway recommendations and disposition in patients with chest pain: a post hoc analysis of a randomised controlled trial. Emergency Medicine Journal, emermed-2025. doi: 10.1136/emermed-2025-215527
2026
Journal Article
National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025
Brieger, David B., Cullen, Louise A., Briffa, Tom G., Zaman, Sarah, Scott, Ian A., Papendick, Cynthia, Ho, Elaine, Leitch, Victoria, Dougherty, Dannii and Jennings, Garry (2026). National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025. Medical Journal of Australia, 224 (2) e70127, e70127-2. doi: 10.5694/mja2.70127
2026
Journal Article
New pathways with high-sensitivity cardiac troponin testing at the point of care in the ambulance and primary care
Johannessen, Tonje Rambøll, Body, Richard, Mair, Johannes, Mills, Nicholas L., Cullen, Louise, Lindahl, Bertil, Boeddinghaus, Jasper, Daniels, Lori, Hammarsten, Ola, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan, Kimenai, Dorien M., Krychtiuk, Konstantin A., Möckel, Martin, Mueller, Christian, Thielmann, Matthias and Thygesen, Kristian (2026). New pathways with high-sensitivity cardiac troponin testing at the point of care in the ambulance and primary care. European Heart Journal: Acute Cardiovascular Care, 15 (2), 148-150. doi: 10.1093/ehjacc/zuaf157
2026
Journal Article
Predictive Symptoms for Acute Coronary Syndrome in Aboriginal and Torres Strait Islander People Assessed in the Emergency Department
Stephensen, Laura C., Gatton, Michelle L., Mahoney, Ray, Parsonage, William, Greenslade, Jaimi H. and Cullen, Louise (2026). Predictive Symptoms for Acute Coronary Syndrome in Aboriginal and Torres Strait Islander People Assessed in the Emergency Department. EMA - Emergency Medicine Australasia, 38 (1) e70222, 1. doi: 10.1111/1742-6723.70222
2026
Journal Article
Best of cardiovascular biomarkers in 2025
Mair, Johannes, Mills, Nicholas L., Lindahl, Bertil, Boeddinghaus, Jasper, Cullen, Louise, Daniels, Lori, Hammarsten, Ola, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan S., Kimenai, Dorien M., Krychtiuk, Konstantin A., Möckel, Martin, Mueller, Christian, Thielmann, Matthias and Thygesen, Kristian (2026). Best of cardiovascular biomarkers in 2025. European Heart Journal: Acute Cardiovascular Care, 15 (2), 144-147. doi: 10.1093/ehjacc/zuaf151
2026
Journal Article
Corrigendum to: National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Comprehensive Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025” [Heart Lung Circ. 34(4) (2025) 309–397.]
Brieger, David, Cullen, Louise, Briffa, Tom, Zaman, Sarah, Scott, Ian, Papendick, Cynthia, Bardsley, Kimberley, Baumann, Angus, Bennett, Alexandra (Sasha), Clark, Robyn A., Edelman, J. James, Inglis, Sally C., Kuhn, Lisa, Livori, Adam, Redfern, Julie, Schneider, Hans, Stewart, Jeanine, Thomas, Liza, Wing-Lun, Edwina, Zhang, Ling, Ho, Elaine and Matthews, Stacey (2026). Corrigendum to: National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Comprehensive Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025” [Heart Lung Circ. 34(4) (2025) 309–397.]. Heart, Lung and Circulation, 35 (1), e12-e13. doi: 10.1016/j.hlc.2025.12.009
2026
Journal Article
Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting
Collinson, Paul, Lam, Leo, Pickering, John W., Christenson, Robert, Van Hoovels, Lieve, Jafri, Lena, Cullen, Louise, Jaffe, Allan S., Apple, Fred S., Hammarsten, Ola, Omland, Torbjorn, Sandoval, Yader, Mills, Nicholas L., Than, Martin, Buchan, Vanessa, Sandberg, Sverre and Aakre, Kristin M. (2026). Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting. Clinical Chemistry and Laboratory Medicine. doi: 10.1515/cclm-2026-0210
2025
Journal Article
The Limit of Detection in the Emergency Department Trial (LEGEND): a stepped-wedge cluster randomized trial to rule out acute myocardial infarction and reduce hospital length of stay for patients presenting to the emergency department
Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Parsons, Rex, Perez, Siegfried, Starmer, Katrina, Starmer, Gregory, Gaikwad, Niranjan, McPhail, Steven M., Hall, Emma, Brownlee, Emily, McCormick, Ellyse, Cullen, Louise, Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Perez, Siegfried, Starmer, Katrina, Starmer, Gregory, Gaikwad, Niranjan, McPhail, Steven M., Hall, Emma, Brownlee, Emily, McCormick, Ellyse, Bonnin, Robert, Brain, David, Campbell, Virginia, Charters, Brooke, Chew, Derek ... Cullen, Louise (2025). The Limit of Detection in the Emergency Department Trial (LEGEND): a stepped-wedge cluster randomized trial to rule out acute myocardial infarction and reduce hospital length of stay for patients presenting to the emergency department. Annals of Emergency Medicine. doi: 10.1016/j.annemergmed.2025.10.014
2025
Journal Article
Health Services and Economic Impacts of the Limit of Detection in Emergency Department (LEGEND) Rule-Out Strategy in Australian Emergency Departments: A Stepped-Wedge Cluster Randomised Trial
Dobson, Olivia, Cullen, Louise, Parsonage, William, Stephensen, Laura, Brain, David, Mcphail, Steven, Hall, Emma, Gaikwad, Niranjan, Perez, Siegfried, Starmer, Katrina, Starmer, Gregory, Greenslade, Jaimi, Greenslade, Jaimi, Cullen, Louise, Parsonage, William, Stephensen, Laura, Bonnin, Robert, Brain, David, Brownlee, Emily, Campbell, Virginia, Charters, Brooke, Chew, Derek, Figtree, Gemma, Funk, Vanessa, Fincher, Gavin, Gaikwad, Niranjan, Hall, Emma, Hamilton-Craig, Christian, McCormick, Ellyse ... Stone, Richard (2025). Health Services and Economic Impacts of the Limit of Detection in Emergency Department (LEGEND) Rule-Out Strategy in Australian Emergency Departments: A Stepped-Wedge Cluster Randomised Trial. EMA - Emergency Medicine Australasia, 37 (5) e70129, 5. doi: 10.1111/1742-6723.70129
2025
Journal Article
The assessment and management of patients with type 2 myocardial infarction: an international Delphi study
Taggart, Caelan, Ferry, Amy V, Chapman, Andrew R, Schulberg, Stacey D, Bularga, Anda, Wereski, Ryan, Boeddinghaus, Jasper, Kimenai, Dorien M, Lowry, Matthew T H, Chew, Derek P, Cullen, Louise, Daniels, Lori B, Devereaux, P J, French, John, Gaggin, Hanna K, Huynh, Thao, Jacquin, Laurent, Jaffe, Allan S, Jernberg, Tomas, Koronowski, Ran, McCarthy, Cian, McCord, James, Mamas, Mamas A, Mickley, Hans, Morrow, David A, Mueller, Christian, Newby, L Kristin, Parsonage, William, Raphael, Claire E ... Mills, Nicholas L (2025). The assessment and management of patients with type 2 myocardial infarction: an international Delphi study. European Heart Journal - Quality of Care and Clinical Outcomes, 11 (8) qcaf069, 1421-1430. doi: 10.1093/ehjqcco/qcaf069
2025
Journal Article
Cost-effectiveness of the transition from conventional to high-sensitivity troponin assay for the investigation and management of suspected acute coronary syndrome in the emergency department
Pincombe, Aubyn, Gray, Jodi, Hickling, Siobhan, Sanfilippo, Frank, Briffa, Tom, Cullen, Louise, Chew, Derek, Hillis, Graham, Fatovich, Daniel, Rankin, Jamie, Nedkoff, Lee, Scanlan, Samuel, Hickman, Peter E., Stapleton, Stuart, Parsonage, William, Mitra, Biswadev, Schneider, Hans G., Wilkes, Garry, Robinson, Teagan and Karnon, Jonathan (2025). Cost-effectiveness of the transition from conventional to high-sensitivity troponin assay for the investigation and management of suspected acute coronary syndrome in the emergency department. American Heart Journal, 287, 107-118. doi: 10.1016/j.ahj.2025.03.022
2025
Journal Article
Potential impact of a point-of-care high-sensitivity cardiac troponin assay on emergency department length of stay and patient disposition: findings from a cardiac emergency department
Meek, Robert, Lu, Zhong Xian, Senarathne, Udara Dilrukshi, Tan, Sean, Cullen, Louise, Pickering, John W, Than, Martin Paul, Hayden, Georgina, Damianopoulos, Adam, Charteris, Claire, Duong, Alex and Egerton-Warburton, Diana (2025). Potential impact of a point-of-care high-sensitivity cardiac troponin assay on emergency department length of stay and patient disposition: findings from a cardiac emergency department. Emergency Medicine Journal, 43 (1), emermed-2025. doi: 10.1136/emermed-2025-214985
2025
Conference Publication
Acute Coronary Syndrome Symptomatology in Aboriginal and Torres Strait Islander People
Stephensen, L., Mahoney, R., Parsonage, W., Cullen, L., Greenslade, J. and Gatton, M. (2025). Acute Coronary Syndrome Symptomatology in Aboriginal and Torres Strait Islander People. 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Brisbane, QLD Australia, 14-17 August 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.06.801
2025
Journal Article
Effectiveness of point-of-care high-sensitivity troponin testing in the emergency department: a randomized controlled trial
Thulin, Viola I.L., Jordalen, Silje M.F., Myrmel, Gard M.S., Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole Thomas, Body, Richard, Collinson, Paul, Apple, Fred S., Cullen, Louise, Norekvål, Tone M., Wisløff, Torbjørn, Vikenes, Kjell, Bjørneklett, Rune O., Omland, Torbjørn and Aakre, Kristin M. (2025). Effectiveness of point-of-care high-sensitivity troponin testing in the emergency department: a randomized controlled trial. Annals of Emergency Medicine, 86 (2), 124-135. doi: 10.1016/j.annemergmed.2025.03.005
2025
Journal Article
Re-engineering the clinical approach to suspected cardiac chest pain assessment in the emergency department by expediting research evidence to practice using artficial intelligence. (RAPIDx AI) – a cluster randomised study design
Khan, Ehsan, Lambrakis, Kristina, Briffa, Tom, Cullen, Louise A., Karnon, Jonathon, Papendick, Cynthia, Quinn, Stephen, Tideman, Phil, Hengel, Anton Van Den, Verjans, Johan and Chew, Derek P. (2025). Re-engineering the clinical approach to suspected cardiac chest pain assessment in the emergency department by expediting research evidence to practice using artficial intelligence. (RAPIDx AI) – a cluster randomised study design. American Heart Journal, 285, 106-118. doi: 10.1016/j.ahj.2025.02.016
2025
Conference Publication
Listening to See: Co-Designing the Powerful Pictures Model of Care With Aboriginal and Torres Strait Islander Communities and Health Services
Goodman, A., Allen, M., McKivett, A., Thorne, T., Stephenson, L., Cullen, L., Parsonage, W. and Mahoney, R. (2025). Listening to See: Co-Designing the Powerful Pictures Model of Care With Aboriginal and Torres Strait Islander Communities and Health Services. Cardiac Society of Australia and New Zealand 4th Indigenous Cardiovascular Health Conference 2025, Sydney, NSW Australia, 17–19 June 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.05.012
2025
Conference Publication
Costs and Healthcare Utilisation for Aboriginal and Torres Strait Islander People With Suspected Acute Coronary Syndrome
Stephensen, L., Mahoney, R., Cullen, L. and Parsonage, W. (2025). Costs and Healthcare Utilisation for Aboriginal and Torres Strait Islander People With Suspected Acute Coronary Syndrome. Cardiac Society of Australia and New Zealand 4th Indigenous Cardiovascular Health Conference 2025, Sydney, NSW Australia, 17–19 June 2025. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.05.069
2025
Journal Article
Implementing best practice for peripheral intravenous cannula use in Australian emergency departments: a stepped-wedge cluster-controlled trial and health economic analysis protocol
Egerton-Warburton, Diana, Kuhn, Lisa, Enticott, Joanne, Yang, Sundy Ni-Yen, Buntine, Paul, Callander, Emily, Cullen, Louise, Fatovich, Daniel, Hullick, Carolyn, Heiss, Leah, Keijzers, Gerben, Le, Long Khanh-Dao, Mihalopoulos, Cathrine, Morphet, Julia, O’Reilly, Gerard, Pokhrel, Bibesh, Rickard, Claire, Tran, Viet, Cameron, Peter and Teede, Helena J. (2025). Implementing best practice for peripheral intravenous cannula use in Australian emergency departments: a stepped-wedge cluster-controlled trial and health economic analysis protocol. BMJ Open, 15 (6) e096962, 1-10. doi: 10.1136/bmjopen-2024-096962
2025
Journal Article
Prognostic implications of machine learning algorithm–supported diagnostic classification of myocardial injury using the fourth universal definition of myocardial infarction
Lambrakis, Kristina, Khan, Ehsan, Liao, Zhibin, Gerlach, Joey, Nelson, Adam J., Goodman, Shaun G., Briffa, Tom, Cullen, Louise, Verjans, Johan and Chew, Derek P. (2025). Prognostic implications of machine learning algorithm–supported diagnostic classification of myocardial injury using the fourth universal definition of myocardial infarction. Heart Lung and Circulation, 34 (5), 497-505. doi: 10.1016/j.hlc.2024.11.023
Funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Completed supervision
-
2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
-
2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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