Overview
Background
Louise Cullen is a Pre-Eminent Staff Specialist in Emergency Medicine, a clinical trialist and outcomes researcher in acute diseases. She is enthusiastically involved in the translation of research by clinical redesign and innovation.
As an accomplished acute disease researcher, Prof Cullen has focused on the diagnosis and management of patients presenting with possible Acute Coronary Syndromes (ACS) in the Emergency Department (ED). She has been engaged in many international collaborations (including ASPECT and ADAPT studies) She has authored over 100 publications in peer-reviewed journals including The Lancet, focussed on strategies to improve efficiency, whilst maintaining safety for patients with possible ACS, syncope, heart failure, shortness of breath and atrial fibrillation.
More recently Prof Cullen has focussed on Health Services research and investigating methods to use medications and other resources in the ED wisely. She led the CREDIT trail, aimed at reducing unnecessary peripheral intravenous cannulation in the ED.
Professor Cullen’s mantra is that “you do not do research for research sake” and as such, clinical redesign and translational research is a key part of her endeavours.
Pre-Eminent Staff Specialist, Department of Emergency Medicine
Prof, Queensland University of Technology
A/Prof, University of Queensland
Royal Brisbane and Women’s Hospital
Brisbane, Queensland 4029, AUSTRALIA.
Tel: (+ 61 7) 3636 7901. Fax: (+ 61 7) 3636 1643.
Email: louise.cullen@health.qld.gov.au
Twitter: @louiseacullen
Qualifications: MBBS (Hon) FACEM PhD
Availability
- Professor Louise Cullen is:
- Available for supervision
Fields of research
Research impacts
Prof Cullen has been extensively involved translation of research findings into changed clinical practice. She is currently the Clinical Lead in the Accelerated Chest pain Risk Evaluation project (ACRE 2012-8), implementing changed practice models of care across Queensland Health for ED patients based on her research. This change has translated into significant improvements in ED efficiency while maintaining patient safety. She was awarded the Metro North Chief Executive Award for Research in 2018, QH Metro North Research Excellence Award: Integrated Care and Health Services Research in 2016, the Australian Society for Medical Research: Clinical Research winner in 2016 and Most Outstanding Redesign Practitioner in 2013.
Works
Search Professor Louise Cullen’s works on UQ eSpace
2026
Journal Article
Incidence of acute coronary syndrome assessment among adult emergency department presentations: a multicentre study
Greenslade, Jaimi H, Stephensen, Laura, Parsonage, William and Cullen, Louise (2026). Incidence of acute coronary syndrome assessment among adult emergency department presentations: a multicentre study. Emergency Medicine Journal, emermed-2026. doi: 10.1136/emermed-2026-216302
2026
Journal Article
Geographical Access to Computed Tomography Coronary Angiography in Australia
Nesterenko, V., Cramb, S., Parsonage, W., Stephensen, L., Mahoney, R., Greenslade, J., Tyack, Z., Brown, N., Goodman, A., Scholte, C., McCreanor, V. and Cullen, L. (2026). Geographical Access to Computed Tomography Coronary Angiography in Australia. Heart, Lung and Circulation, 35, S146-S147. doi: 10.1016/j.hlc.2026.07.134
2026
Journal Article
A Shift in Mindset: From ST Elevation to Acute Coronary Occlusion Myocardial Infarction (ACOMI)
Makarious, David, Fairley, Sarah, Harding, Scott, Stehli, Julia, Cullen, Louise, Brieger, David and Zaman, Sarah (2026). A Shift in Mindset: From ST Elevation to Acute Coronary Occlusion Myocardial Infarction (ACOMI). Heart, Lung and Circulation. doi: 10.1016/j.hlc.2026.02.025
2026
Journal Article
Artificial Intelligence-based Clinical Decision Support May Reduce Sex Disparities in Suspected ACS: Sub-Analysis of a Multicentre Cluster-Randomised Trial
Rebecca, R., Lambrakis, K., Khan, E., Briffa, T., Cullen, L., Verjans, J., Karnon, J., Papendick, C. and Chew, D. (2026). Artificial Intelligence-based Clinical Decision Support May Reduce Sex Disparities in Suspected ACS: Sub-Analysis of a Multicentre Cluster-Randomised Trial. Heart, Lung and Circulation, 35, S399. doi: 10.1016/j.hlc.2026.07.597
2026
Journal Article
Utility of high-sensitivity cardiac troponin I normalized to left ventricular mass in detection of stable coronary artery disease
Fathieh, Sina, Gray, Michael P., Tang, Owen, Bate, Katharine A., Vernon, Stephen T., Genetzakis, Elijah, Saleh, Soloman, Murtagh, Gillian, Yang, Jean Y., Tran, Collin, Sullivan, David R., Bonnitcha, Paul, Celermajer, David S., Cullen, Louise, Bhindi, Ravinay, Mayet, Jamil, Nicholls, Stephen J., Grieve, Stuart M. and Figtree, Gemma A. (2026). Utility of high-sensitivity cardiac troponin I normalized to left ventricular mass in detection of stable coronary artery disease. Nature Cardiovascular Research, 5 (8), 763-776. doi: 10.1038/s44161-026-00837-z
2026
Journal Article
External validation of a universal laboratory pathway for early risk-stratification of myocardial infarction in the emergency setting
Kavsak, Peter A., Pickering, John W., Strauß, Bianca, Greenslade, Jaimi H., Thießen, Niklas, Haller, Paul M., Lehmacher, Jonas, Toprak, Betül, Twerenbold, Raphael, Sörensen, Nils Arne, Parsonage, William A., Pemberton, Christopher, Troughton, Richard, Richards, A. Mark, Pardhan, Alim, Mondoux, Shawn E., Sharif, Sameer, Ainsworth, Craig, Ma, Jinhui, Ko, Dennis T., Worster, Andrew, Cullen, Louise, Neumann, Johannes T. and Than, Martin (2026). External validation of a universal laboratory pathway for early risk-stratification of myocardial infarction in the emergency setting. Canadian Journal of Cardiology, 42 (7), 1648-1650. doi: 10.1016/j.cjca.2026.04.023
2026
Journal Article
Identifying symptom clusters predictive of acute myocardial infarction for Aboriginal and Torres Strait Islander and non‐Indigenous Australians
Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Rigney, Jeremy, Starmer, Katrina, Starmer, Gregory, Campbell, Virginia, Hall, Emma, Gaikwad, Niranjan, Perez, Siegfried, Cullen, Louise and the Legend investigators (2026). Identifying symptom clusters predictive of acute myocardial infarction for Aboriginal and Torres Strait Islander and non‐Indigenous Australians. Emergency Medicine Australasia, 38 (3) e70269, 1-9. doi: 10.1111/1742-6723.70269
2026
Journal Article
Current and future indication for testing and use of cardiac troponin in children
Aakre, Kristin M., Jeewa, Aamir, Cullen, Louise, McCrindle, Brian W., Geaghan, Sharon, Decrue, Fabienne, Apple, Fred S., Collinson, Paul O., Hammarsten, Ola, Omland, Torbjørn, Sandoval, Yader, Mills, Nicholas L. and Jaffe, Allan S. (2026). Current and future indication for testing and use of cardiac troponin in children. Clinical Chemistry, 72 (6) hvag021, 625-640. doi: 10.1093/clinchem/hvag021
2026
Journal Article
In reply:
Greenslade, Jaimi and Cullen, Louise (2026). In reply:. Annals of Emergency Medicine, 87 (5), 675-676. doi: 10.1016/j.annemergmed.2026.01.002
2026
Journal Article
The Limit of Detection in the Emergency Department Trial (LEGEND): a stepped-wedge cluster randomized trial to rule out acute myocardial infarction and reduce hospital length of stay for patients presenting to the emergency department
Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Parsons, Rex, Perez, Siegfried, Starmer, Katrina, Starmer, Gregory, Gaikwad, Niranjan, McPhail, Steven M., Hall, Emma, Brownlee, Emily, McCormick, Ellyse, Cullen, Louise, Greenslade, Jaimi, Parsonage, William, Stephensen, Laura, Perez, Siegfried, Starmer, Katrina, Starmer, Gregory, Gaikwad, Niranjan, McPhail, Steven M., Hall, Emma, Brownlee, Emily, McCormick, Ellyse, Bonnin, Robert, Brain, David, Campbell, Virginia, Charters, Brooke, Chew, Derek ... Cullen, Louise (2026). The Limit of Detection in the Emergency Department Trial (LEGEND): a stepped-wedge cluster randomized trial to rule out acute myocardial infarction and reduce hospital length of stay for patients presenting to the emergency department. Annals of Emergency Medicine, 87 (4), 424-434. doi: 10.1016/j.annemergmed.2025.10.014
2026
Journal Article
High-sensitivity point-of-care measurement of cardiac troponin: a scientific statement of the association for acute cardiovascular care of the ESC
Cullen, Louise, Mair, Johannes, Hammarsten, Ola, Stengaard, Carsten, Boeddinghaus, Jasper, Daniels, Lori B, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan S, Kimenai, Dorien M, Krychtiuk, Konstantin A, Lindahl, Bertil, Möckel, Martin, Mueller, Christian, Thielmann, Matthias, Thygesen, Kristian and Mills, Nicholas L (2026). High-sensitivity point-of-care measurement of cardiac troponin: a scientific statement of the association for acute cardiovascular care of the ESC. European Heart Journal, 47 (12) ehaf407, 1392-1402. doi: 10.1093/eurheartj/ehaf407
2026
Journal Article
Modifiers of the effectiveness of point-of-care troponin testing and determinants of concordance between diagnostic pathway recommendations and disposition in patients with chest pain: a post hoc analysis of a randomised controlled trial
Thulin, Viola IL, Myrmel, Gard Mikael Sæle, Jordalen, Silje Marie Farestveit, Lekven, Ole Christian, Krishnapillai, Jeyaseelan, Steiro, Ole-Thomas, Body, Richard, Collinson, Paul O, Apple, Fred, Cullen, Louise, Norekvål, Tone Merete, Wisløff, Torbjørn, Vikenes, Kjell, Bjørneklett, Rune Oskar, Omland, Torbjørn and Aakre, Kristin Moberg (2026). Modifiers of the effectiveness of point-of-care troponin testing and determinants of concordance between diagnostic pathway recommendations and disposition in patients with chest pain: a post hoc analysis of a randomised controlled trial. Emergency Medicine Journal. doi: 10.1136/emermed-2025-215527
2026
Journal Article
Best of cardiovascular biomarkers in 2025
Mair, Johannes, Mills, Nicholas L., Lindahl, Bertil, Boeddinghaus, Jasper, Cullen, Louise, Daniels, Lori, Hammarsten, Ola, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan S., Kimenai, Dorien M., Krychtiuk, Konstantin A., Möckel, Martin, Mueller, Christian, Thielmann, Matthias and Thygesen, Kristian (2026). Best of cardiovascular biomarkers in 2025. European Heart Journal: Acute Cardiovascular Care, 15 (2), 144-147. doi: 10.1093/ehjacc/zuaf151
2026
Journal Article
National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025
Brieger, David B., Cullen, Louise A., Briffa, Tom G., Zaman, Sarah, Scott, Ian A., Papendick, Cynthia, Ho, Elaine, Leitch, Victoria, Dougherty, Dannii and Jennings, Garry (2026). National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025. Medical Journal of Australia, 224 (2) e70127, 1-19. doi: 10.5694/mja2.70127
2026
Journal Article
New pathways with high-sensitivity cardiac troponin testing at the point of care in the ambulance and primary care
Johannessen, Tonje Rambøll, Body, Richard, Mair, Johannes, Mills, Nicholas L., Cullen, Louise, Lindahl, Bertil, Boeddinghaus, Jasper, Daniels, Lori, Hammarsten, Ola, Huber, Kurt, Giannitsis, Evangelos, Jaffe, Allan, Kimenai, Dorien M., Krychtiuk, Konstantin A., Möckel, Martin, Mueller, Christian, Thielmann, Matthias, Thygesen, Kristian and Study Group on Biomarkers of the ESC Association for Acute Cardiovascular Care (2026). New pathways with high-sensitivity cardiac troponin testing at the point of care in the ambulance and primary care. European Heart Journal: Acute Cardiovascular Care, 15 (2), 148-150. doi: 10.1093/ehjacc/zuaf157
2026
Journal Article
Predictive symptoms for acute coronary syndrome in Aboriginal and Torres Strait Islander people assessed in the emergency department
Stephensen, Laura C., Gatton, Michelle L., Mahoney, Ray, Parsonage, William, Greenslade, Jaimi H. and Cullen, Louise (2026). Predictive symptoms for acute coronary syndrome in Aboriginal and Torres Strait Islander people assessed in the emergency department. EMA - Emergency Medicine Australasia, 38 (1) e70222, 1-9. doi: 10.1111/1742-6723.70222
2026
Journal Article
A new 0- and 2-hour risk assessment for acute myocardial infarction in emergency department patients using a high sensitivity point of care troponin assay
Cullen, Louise, Greenslade, Jaimi H, Gaikwad, Niranjan, Stephensen, Laura, Brownlee, Emily, McCormick, Ellyse, Hall, Emma J, Van Niekerk, Megan, Bayat, Maryam Khorramshahi, Mahmoodi, Ehsan, Parsonage, William, SAMIE investigators, Cullen, Louise, Greenslade, Jaimi, Stephensen, Laura, Ranasinghe, Isuru, Gaikwad, Niranjan, Bayat, Maryam Khorramshahi, Mahmoodi, Eshan, Than, Martin, Apple, Fred S, Parsonage, William, Brownlee, Emily, Fincher, Gavin, Gangathimmaiah, Vinay, Hall, Emma, Hamilton-Craig, Christian, Hancock, Rebecca, Hobbins-King, Andrew ... Zournazi, Anna (2026). A new 0- and 2-hour risk assessment for acute myocardial infarction in emergency department patients using a high sensitivity point of care troponin assay. European Heart Journal: Acute Cardiovascular Care, 15 (1), 24-31. doi: 10.1093/ehjacc/zuaf143
2026
Journal Article
Corrigendum to: National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Comprehensive Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025” [Heart Lung Circ. 34(4) (2025) 309–397.]
Brieger, David, Cullen, Louise, Briffa, Tom, Zaman, Sarah, Scott, Ian, Papendick, Cynthia, Bardsley, Kimberley, Baumann, Angus, Bennett, Alexandra (Sasha), Clark, Robyn A., Edelman, J. James, Inglis, Sally C., Kuhn, Lisa, Livori, Adam, Redfern, Julie, Schneider, Hans, Stewart, Jeanine, Thomas, Liza, Wing-Lun, Edwina, Zhang, Ling, Ho, Elaine and Matthews, Stacey (2026). Corrigendum to: National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Comprehensive Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025” [Heart Lung Circ. 34(4) (2025) 309–397.]. Heart, Lung and Circulation, 35 (1), e12-e13. doi: 10.1016/j.hlc.2025.12.009
2026
Journal Article
Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting
Collinson, Paul, Lam, Leo, Pickering, John W., Christenson, Robert, Van Hoovels, Lieve, Jafri, Lena, Cullen, Louise, Jaffe, Allan S., Apple, Fred S., Hammarsten, Ola, Omland, Torbjorn, Sandoval, Yader, Mills, Nicholas L., Than, Martin, Buchan, Vanessa, Sandberg, Sverre and Aakre, Kristin M. (2026). Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting. Clinical Chemistry and Laboratory Medicine, 64 (7), 1467-1478. doi: 10.1515/cclm-2026-0210
2025
Journal Article
Text message incentives increased patient-reported outcomes survey response in emergency care: SWAT findings
Altinger, Gemma, Sharma, Sweekriti, Li, Qiang, Devaux, Anthony, Darby, Samantha, van Wyk, Aidan, Jones, Caitlin M.P., Maher, Chris G., Traeger, Adrian C., Cullen, Louise, McCaffery, Kirsten, Linder, Jeffrey A., Buchbinder, Rachelle, Harris, Ian A., Coiera, Enrico, Howard, Kirsten, Coggins, Andrew, Middleton, Paul M., Devaux, Anthony, Gunja, Naren, Ferguson, Ian, Chan, Trevor, Tambree, Karen, van Wyk, Aidan, Mallows, James, Pile, Kevin, Cracknell, Richard, Hermiz, Arsalan, Lawrence, Jeremy ... Gloss, Kayla (2025). Text message incentives increased patient-reported outcomes survey response in emergency care: SWAT findings. Journal of Clinical Epidemiology, 191 112116, 112116. doi: 10.1016/j.jclinepi.2025.112116
Funding
Supervision
Availability
- Professor Louise Cullen is:
- Available for supervision
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Supervision history
Completed supervision
-
2017
Doctor Philosophy
Decision Aid Derivation Methods for the Acute Coronary Syndrome Pathway
Principal Advisor
-
2024
Doctor Philosophy
Atrial Fibrillation in Critical Care
Associate Advisor
Other advisors: Associate Professor Robert Boots
Media
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