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Associate Professor Amy McCart Reed
Associate Professor

Amy McCart Reed

Email: 
Phone: 
+61 7 334 66030

Overview

Background

Associate Prof Amy McCart Reed holds a PhD in molecular biology from The University of Queensland. She is a Fellow of the Faculty of Science of the Royal College of Pathologists Australasia. Her early postdoctoral work focused on understanding the genetic basis of colorectal cancer using experimental disease models, as part of a Cancer Research UK-funded colorectal cancer program led by Professors Ian Tomlinson and Andrew Silver. After returning to Australia, she was recruited to the Molecular Breast Pathology group at UQ’s Centre for Clinical Research and has undertaken a series of studies investigating the genomic landscape of breast cancer special types. Amy's research program includes studies on Metaplastic breast cancer and Invasive Lobular Carcinoma, two breast cancer special types in need of targetted therapy options. A/Prof McCart Reed is the scientific lead on an MRFF-funded genomics program investigating the potential for the application of Whole Genome Sequencing in the breast cancer care pathway in Australia, 'Q-IMPROvE'. She applies genomics and spatial transcriptomics methodologies to archival clinical samples to understand the differences between tumour types and their potential for treatment. Amy is passionate about clinical research, biobanking and precision oncology. In addition to her breast cancer research portfolio, she is on the steering committee for the Brisbane Breast Bank and the Scientific Advisory Board for Breast Cancer Trials.

Availability

Associate Professor Amy McCart Reed is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research interests

  • Breast Cancer

  • Genomics

  • Biobanking

  • Molecular pathology

  • Precision medicine

Works

Search Professor Amy McCart Reed’s works on UQ eSpace

110 works between 1999 and 2025

41 - 60 of 110 works

2020

Conference Publication

Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma

Simpson, P., Reed, A. McCart, Kutasovic, J., Coorey, C., Kuo, L., Nguyen, H., Pei, W., Ong, J., Sokolova, A., Evans, E., Porter, A. and Lakhani, S. (2020). Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma. ESMO Breast Cancer Virtual Meeting, Online, 23-24 May 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2020.03.186

Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma

2020

Journal Article

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

Kutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Lakhani, Sunil R. and Simpson, Peter T. (2020). Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer. Cancers, 12 (4) 848, 848. doi: 10.3390/cancers12040848

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

2020

Journal Article

Non-coding RNAs underlie genetic predisposition to breast cancer

Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). Non-coding RNAs underlie genetic predisposition to breast cancer. Genome Biology, 21 (1) 7, 7. doi: 10.1186/s13059-019-1876-z

Non-coding RNAs underlie genetic predisposition to breast cancer

2020

Book Chapter

Metaplastic breast cancer

Reis-Filho, J.S., Gobbi, H., McCart Reed, A.E., Rakha, E.A., Shin, S.J., Sortiriou, C. and Vincent-Salomon, A. (2020). Metaplastic breast cancer. WHO Classification of Tumours: Breast Tumours. (pp. 134-138) edited by WHO Classification of Tumours Editorial Board. Geneva, Switzerland: World Health Organization.

Metaplastic breast cancer

2019

Journal Article

LobSig is a multigene predictor of outcome in invasive lobular carcinoma

McCart Reed, Amy E., Lal, Samir, Kutasovic, Jamie R., Wockner, Leesa, Robertson, Alan, de Luca, Xavier M., Kalita-de Croft, Priyakshi, Dalley, Andrew J., Coorey, Craig P., Kuo, Luyu, Ferguson, Kaltin, Niland, Colleen, Miller, Gregory, Johnson, Julie, Reid, Lynne E., Males, Renique, Saunus, Jodi M., Chenevix-Trench, Georgia, Coin, Lachlan, Lakhani, Sunil R. and Simpson, Peter T. (2019). LobSig is a multigene predictor of outcome in invasive lobular carcinoma. npj Breast Cancer, 5 (1) 18, 18. doi: 10.1038/s41523-019-0113-y

LobSig is a multigene predictor of outcome in invasive lobular carcinoma

2019

Journal Article

A molecular and morphological deep-dive into metaplastic breast cancers

McCart Reed, Amy E. and Lakhani, Sunil R. (2019). A molecular and morphological deep-dive into metaplastic breast cancers. Cancer Informatics, 18, 1-2. doi: 10.1177/1176935119850155

A molecular and morphological deep-dive into metaplastic breast cancers

2019

Journal Article

Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers

Nones, K., Johnson, J., Newell, F., Patch, A. M., Thorne, H., Kazakoff, S. H., de Luca, X. M., Parsons, M. T., Ferguson, K., Reid, L. E., McCart Reed, A. E., Srihari, S., Lakis, V., Davidson, A. L., Mukhopadhyay, P., Holmes, O., Xu, Q., Wood, S., Leonard, C., The Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), The Australian Breast Cancer Tissue Bank (ABCTB), The Brisbane Breast Bank (BBB), Beesley, J., Harris, J. M., Barnes, D., Degasperi, A., Ragan, M. A., Spurdle, A. B., Khanna, K. K. ... Simpson, P. T. (2019). Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers. Annals of Oncology, 30 (7) mdz132, 1071-1079. doi: 10.1093/annonc/mdz132

Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers

2019

Journal Article

Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks

Fielding, David, Dalley, Andrew J., Bashirzadeh, Farzad, Singh, Mahendra, Nandakumar, Lakshmy, McCart Reed, Amy E., Black, Debra, Kazakoff, Stephen, Pearson, John V., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2019). Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks. Respiration, 97 (6), 1-14. doi: 10.1159/000495661

Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks

2019

Journal Article

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

McCart Reed, Amy Ellen, Kalaw, Emarene, Nones, Katia, Bettington, Mark, Lim, Malcolm, Bennett, James, Johnstone, Kate, Kutasovic, Jamie Rose, Saunus, Jodi Marie, Kazakoff, Stephen, Xu, Qinying, Wood, Scott, Holmes, Oliver, Leonard, Conrad, Reid, Lynne Estelle, Black, Debra, Niland, Colleen, Ferguson, Kaltin, Gresshoff, Irma, Raghavendra, Ashwini, Harvey, Kate, Cooper, Caroline, Liu, Cheng, Kalinowski, Lauren, Reid, Andrew Scott, Davidson, Morgan, Pearson, John V, Pathmanathan, Nirmala, Tse, Gary ... Lakhani, Sunil R. (2019). Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications. Journal of Pathology, 247 (2), 214-227. doi: 10.1002/path.5184

Phenotypic and molecular dissection of Metaplastic Breast Cancer and the prognostic implications

2019

Book Chapter

Breast cancer heterogeneity in primary and metastatic disease

Kalinowski, Lauren, Saunus, Jodi M., McCart Reed, Amy E. and Lakhani, Sunil R. (2019). Breast cancer heterogeneity in primary and metastatic disease. Breast cancer metastasis and drug resistance: challenges and progress. (pp. 75-104) edited by Aamir Ahmad. Cham, Switzerland: Springer. doi: 10.1007/978-3-030-20301-6_6

Breast cancer heterogeneity in primary and metastatic disease

2019

Conference Publication

LobSig, a prognostic signature for Invasive Lobular Carcinoma

McCart Reed, Amy E., Lal, Samir, Kutasovic, Jamie R., Wockner, Leesa, Robertson, Alan, de Croft, Priyakshi Kalıta, Dalley, Andrew, Coorey, Craig P., Kuo, Luyu, Ferguson, Kaltin, Niland, Colleen, Miller, Gregory, Johnson, Julie, Reid, Lynne E., Males, Renique, Saunus, Jodi M., Chenevix-Trench, Georgia, Coin, Lachlan, Lakhani, Sunil R. and Simpson, Peter T. (2019). LobSig, a prognostic signature for Invasive Lobular Carcinoma. 7th International PacRim Breast and Prostate Cancer Meeting, Barossa Novotel, South Australia, Australia, 17-20 March 2019.

LobSig, a prognostic signature for Invasive Lobular Carcinoma

2019

Journal Article

Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study

Kutasovic, Jamie R., McCart Reed, Amy E., Males, Renique, Sim, Sarah, Saunus, Jodi M., Dalley, Andrew, McEvoy, Christopher R., Dedina, Liana, Miller, Gregory, Peyton, Stephen, Reid, Lynne, Lal, Samir, Niland, Colleen, Ferguson, Kaltin, Fellowes, Andrew P., Al-Ejeh, Fares, Lakhani, Sunil R., Cummings, Margaret C. and Simpson, Peter T. (2019). Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study. The Journal of Pathology: Clinical Research, 5 (1), 25-39. doi: 10.1002/cjp2.118

Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study

2019

Conference Publication

Using whole genome sequencing and somatic mutation signatures to unravel insight into familial breast cancer aetiology

Simpson, P., Nones, K., Johnson, J., Newell, F., Patch, A-M, Thorne, H., Kazakoff, S., De Luca, X., Parsons, M., Ferguson, K., Reid, L., Reed, A. McCart, Srihari, S., Lakis, V., Davidson, A., Mukhopadhyay, P., Holmes, O., Xu, Q., Wood, S., Leonard, C., Beasley, J., Degasperi, A., Nik-Zainal, S., Ragan, M., Spurdle, A., Khanna, K. K., Lakhani, S., Pearson, J., Chenevix-Trench, G. and Waddell, N. (2019). Using whole genome sequencing and somatic mutation signatures to unravel insight into familial breast cancer aetiology. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P5-10-01

Using whole genome sequencing and somatic mutation signatures to unravel insight into familial breast cancer aetiology

2019

Conference Publication

Implementation of precision oncology in breast cancer care in Qld (Q-IMPROvE).

McCart Reed, Amy , Simpson, Peter , Inglis, Po , Green, Ben , Ung, Owen , Snell, Cameron , Woodward, Natasha , Pyke, Chris , Walpole, Euan , Waddell, Nic , Ladwa, Rahul , Santamaria, Gorane , O'Byrne, Ken , McCarthy, Nicole and Lakhani, Sunil (2019). Implementation of precision oncology in breast cancer care in Qld (Q-IMPROvE).. Australian Precision Oncology Symposium, Adelaide, SA Australia, 9-11 November 2019.

Implementation of precision oncology in breast cancer care in Qld (Q-IMPROvE).

2018

Journal Article

Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?

McCart Reed, Amy E, Kalita-de Croft, Priyakshi, Kutasovic, Jamie, Saunus, Jodi M and Lakhani, Sunil R (2018). Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?. The Journal of Pathology, 247 (5), 552-562. doi: 10.1002/path.5199

Recent advances in breast cancer research impacting clinical diagnostic practice : Breast cancer research - where are we now?

2018

Other Outputs

Breast cancer: molecular pathology driving precision oncology

McCart Reed, Amy and Lakhani, Sunil (2018). Breast cancer: molecular pathology driving precision oncology. MJA Insight website: Medical Journal of Australia.

Breast cancer: molecular pathology driving precision oncology

2018

Journal Article

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018). Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 (4), 460-468. doi: 10.1002/path.5040

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology

2018

Journal Article

Corrigendum to "Molecular signatures in breast cancer" [Methods 131 (2017) 135-146]

Lal, Samir, McCart Reed, Amy E., de Luca, Xavier M. and Simpson, Peter T. (2018). Corrigendum to "Molecular signatures in breast cancer" [Methods 131 (2017) 135-146]. Methods, 164-165, 120-120. doi: 10.1016/j.ymeth.2018.01.007

Corrigendum to "Molecular signatures in breast cancer" [Methods 131 (2017) 135-146]

2018

Book Chapter

Breast Cancer: Pathology and Genetics

McCart Reed, Amy E., Kalaw, Emarene, Reid, Andrew and Lakhani, Sunil R. (2018). Breast Cancer: Pathology and Genetics. Encyclopedia of Cancer, Third Edition: Volumes 1-3. (pp. V1:170-V1:183) Elsevier. doi: 10.1016/B978-0-12-801238-3.65263-7

Breast Cancer: Pathology and Genetics

2018

Book Chapter

Breast cancer - pathology and genetics

McCart Reed, Amy Ellen, Kalaw, Emarene, Reid, Andrew Scott and Lakhani, Sunil R. (2018). Breast cancer - pathology and genetics. Encyclopedia of cancer. (pp. 170-183) edited by Paolo Boffetta and Pierre Hainaut. Cambridge, MA United States: Academic Press. doi: 10.1016/B978-0-12-801238-3.65263-7

Breast cancer - pathology and genetics

Funding

Current funding

  • 2024 - 2028
    Reducing invasive lobular carcinoma mortality by enhanced liquid biopsy monitoring
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2024 - 2025
    Prognostic biomarkers in Invasive Lobular Carcinoma
    Peter MacCallum Cancer Centre
    Open grant
  • 2024 - 2029
    The EARLY study: Evaluating the Specificity and feasibility of the EARLY Test for Ovarian Cancer Detetion
    NHMRC Partnership Projects
    Open grant
  • 2024 - 2026
    Proof of concept studies for a novel immunotherapy for triple negative Breast cancer and companion diagnostic
    United States Congressionally Directed Medical Research Programs - Breast Cancer Research Program
    Open grant
  • 2023 - 2025
    High-resolution investigation of pre- and post-neoadjuvant treatment breast cancers
    National Breast Cancer Foundation Investigator Initiated Research Scheme
    Open grant
  • 2020 - 2025
    Whole Genome Sequencing in high-risk breast cancer patients.
    MRFF Genomics Health Futures Mission, Project Grant administered by AusIndustry
    Open grant

Past funding

  • 2019 - 2022
    Lobular Breast Cancer - can we identify the patients likely to have a poor prognosis?
    NHMRC Project Grant
    Open grant
  • 2014 - 2015
    The Brisbane Breast Bank
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2013 - 2015
    Prospective study of breast cancer progression by content analysis of circulating exosomes in serially collected blood samples
    Royal Brisbane and Women's Hospital
    Open grant

Supervision

Availability

Associate Professor Amy McCart Reed is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Associate Professor Amy McCart Reed directly for media enquiries about:

  • breast cancer
  • DNA
  • genomics
  • lobular breast cancer
  • metaplastic breast cancer
  • personalised medicine
  • precision medicine
  • precision oncology

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