
Overview
Background
Associate Prof Amy McCart Reed holds a PhD in molecular biology from The University of Queensland. She is a Fellow of the Faculty of Science of the Royal College of Pathologists Australasia. Her early postdoctoral work focused on understanding the genetic basis of colorectal cancer using experimental disease models, as part of a Cancer Research UK-funded colorectal cancer program led by Professors Ian Tomlinson and Andrew Silver. After returning to Australia, she was recruited to the Molecular Breast Pathology group at UQ’s Centre for Clinical Research and has undertaken a series of studies investigating the genomic landscape of breast cancer special types. Amy's research program includes studies on Metaplastic breast cancer and Invasive Lobular Carcinoma, two breast cancer special types in need of targetted therapy options. A/Prof McCart Reed is the scientific lead on an MRFF-funded genomics program investigating the potential for the application of Whole Genome Sequencing in the breast cancer care pathway in Australia, 'Q-IMPROvE'. She applies genomics and spatial transcriptomics methodologies to archival clinical samples to understand the differences between tumour types and their potential for treatment. Amy is passionate about clinical research, biobanking and precision oncology. In addition to her breast cancer research portfolio, she is on the steering committee for the Brisbane Breast Bank and the Scientific Advisory Board for Breast Cancer Trials.
Availability
- Associate Professor Amy McCart Reed is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Breast Cancer
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Genomics
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Biobanking
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Molecular pathology
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Precision medicine
Works
Search Professor Amy McCart Reed’s works on UQ eSpace
2007
Journal Article
Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma
Patel, Heena, Polanco-Echeverry, Guadalupe, Segditsas, Stefania, Volikos, Emmanouil, McCart, Amy, Lai, Cecilia, Guenther, Thomas, Zaitoun, Abed, Ilyas, Mohammed, Northover, John and Silver, Anrew (2007). Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma. International Journal of Cancer, 121 (12), 2668-2673. doi: 10.1002/ijc.23028
2007
Journal Article
Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP
Suraweera, Nirosha, Latchford, Andrew, McCart, Amy, Rogers, Pauline, Spain, Sarah, Sieber, Oliver, Phillips, Robin, Tomlinson, Ian and Silver, Andrew (2007). Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP. Journal of Medical Genetics, 44 (8), 541-544. doi: 10.1136/jmg.2007.049965
2006
Journal Article
Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice
Suraweera, N., Haines, J., McCart, A., Rogers, P., Latchford, A., Coster, M., Polanco-Echeverry, G., Guenther, T., Wang, J., Sieber, O. and Silver, A. (2006). Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice. Human Molecular Genetics, 15 (23), 3429-3435. doi: 10.1093/hmg/ddl419
2006
Journal Article
A novel exon duplication event leading to a truncating germ-line mutation of the APC gene in a Familial Adenomatous Polyposis family
McCart, Amy, Latchford, Andrew, Volikos, Emmanouil, Rowan, Andrew, Tomlinson, Ian and Silver, Andrew (2006). A novel exon duplication event leading to a truncating germ-line mutation of the APC gene in a Familial Adenomatous Polyposis family. Familial Cancer, 5 (2), 205-208. doi: 10.1007/s10689-006-7471-y
2005
Other Outputs
Analysis of kinesin light chain 1 isoforms
McCart, Amy Ellen (2005). Analysis of kinesin light chain 1 isoforms. PhD Thesis, School of Molecular and Microbial Sciences, The University of Queensland. doi: 10.14264/107279
2004
Conference Publication
Alternative splicing of KNS2 (Kinesin Light Chain 1)
McCart, Amy, Mahony, Donna and Rothnagel, Joseph (2004). Alternative splicing of KNS2 (Kinesin Light Chain 1). 25th Annual Lorne Conference on the Organization and Expression of the Genome, Lorne, VIC, Australia, 15-19 February 2004.
2003
Conference Publication
Alternative splicing of Kinesin Light Chain 1 (KNS2)
McCart, Amy, Mahony, Donna and Rothnagel, Joseph (2003). Alternative splicing of Kinesin Light Chain 1 (KNS2). ComBio 2003, Melbourme, VIC, Australia, 28 September - 2 October 2003.
2003
Journal Article
Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene
McCart, A. E., Mahony, D. and Rothnagel, J. A. (2003). Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene. Traffic, 4 (8), 576-580. doi: 10.1034/j.1600-0854.2003.00113.x
2002
Conference Publication
Alternative splicing of kinesin light chain 1 (KNS2) gene
McCart, Amy, Mahony Donna and Rothnagel Joseph (2002). Alternative splicing of kinesin light chain 1 (KNS2) gene. Boden Conference Developmental Cutaneous Biology, Stradbroke Island, Australia, 14-18 April 2002. St Lucia QLD, Australia: The Uniiversity of Queensland.
1999
Conference Publication
Comparative genomic and detailed structural analysis of the GABA neurotransmitter transporter gene family between vertebrates and the invertebrates, Apis Mellifera and C.elegans
Dutton, P., Mccart, A., Whitehall, V. L. and Ebert, P. R. (1999). Comparative genomic and detailed structural analysis of the GABA neurotransmitter transporter gene family between vertebrates and the invertebrates, Apis Mellifera and C.elegans. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Aust. Society for Biochemistry and Molecular Biology.
Funding
Current funding
Past funding
Supervision
Availability
- Associate Professor Amy McCart Reed is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Investigating therapeutic vulnerabilities in breast cancer.
Principal Advisor
Other advisors: Professor Sunil Lakhani, Associate Professor Peter Simpson
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Doctor Philosophy
Circulating biomarkers in invasive lobular breast carcinoma
Principal Advisor
Other advisors: Professor Sunil Lakhani, Associate Professor Peter Simpson
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Master Philosophy
E-cadherin, ROS1 and synthetic lethality in ILC
Associate Advisor
Other advisors: Professor Sunil Lakhani
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Master Philosophy
Application of molecular genetics in Translational Breast Cancer Research
Associate Advisor
Other advisors: Associate Professor Peter Simpson, Professor Sunil Lakhani
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Master Philosophy
Applications of Molecular Genetics in Translational Breast Cancer Research
Associate Advisor
Other advisors: Associate Professor Peter Simpson, Professor Sunil Lakhani
Completed supervision
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2024
Doctor Philosophy
Identifying and characterising targetable proteins in breast cancer brain metastasis
Principal Advisor
Other advisors: Professor Sunil Lakhani
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2021
Doctor Philosophy
Detailed Characterisation of Metaplastic Breast Carcinoma
Principal Advisor
Other advisors: Dr Jodi Saunus, Professor Sunil Lakhani
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2021
Doctor Philosophy
Multi-omics: Leveraging omics data integration to identify dysregulated biology in breast cancer
Associate Advisor
Other advisors: Dr Katia Nones, Associate Professor Peter Simpson
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2019
Doctor Philosophy
Identifying novel potential prognostic biomarkers in breast cancer
Associate Advisor
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2018
Doctor Philosophy
Genomic and transcriptomic biomarkers of prognosis in invasive lobular breast cancer.
Associate Advisor
Other advisors: Professor Sunil Lakhani, Associate Professor Peter Simpson
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2016
Doctor Philosophy
Intratumour heterogeneity in the development and progression of breast cancer
Associate Advisor
Other advisors: Professor Sunil Lakhani, Associate Professor Peter Simpson
Media
Enquiries
Contact Associate Professor Amy McCart Reed directly for media enquiries about:
- breast cancer
- DNA
- genomics
- lobular breast cancer
- metaplastic breast cancer
- personalised medicine
- precision medicine
- precision oncology
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