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2023 Journal Article Macrophage heterogeneity in the single cell era: facts and artefactsHume, David A., Millard, Susan M. and Pettit, Allison R. (2023). Macrophage heterogeneity in the single cell era: facts and artefacts. Blood Journal, 142 (16), 1339-1347. doi: 10.1182/blood.2023020597 |
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2023 Journal Article Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesisSehgal, Anuj, Carter‐Cusack, Dylan, Keshvari, Sahar, Patkar, Omkar, Huang, Stephen, Summers, Kim M., Hume, David A. and Irvine, Katharine M. (2023). Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis. European Journal of Immunology, 53 (8) 2250312, e2250312. doi: 10.1002/eji.202250312 |
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2023 Journal Article Rare genetic variants underlie outlying levels of DNA methylation and gene-expressionChundru, V. Kartik, Marioni, Riccardo E., Pendergast, James G. D., Lin, Tian, Beveridge, Allan J., Martin, Nicholas G, Montgomery, Grant W., Hume, David A., Deary, Ian J., Visscher, Peter M., Wray, Naomi R. and McRae, Allan F. (2023). Rare genetic variants underlie outlying levels of DNA methylation and gene-expression. Human Molecular Genetics, 32 (11), 1912-1921. doi: 10.1093/hmg/ddad028 |
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2023 Journal Article Fate‐mapping studies in inbred mice: a model for understanding macrophage development and homeostasis?Hume, David A. (2023). Fate‐mapping studies in inbred mice: a model for understanding macrophage development and homeostasis?. European Journal of Immunology, 53 (6) 2250242, e2250242. doi: 10.1002/eji.202250242 |
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2023 Journal Article Apoptotic cell fragments locally activate tingible body macrophages in the germinal centerGrootveld, Abigail K., Kyaw, Wunna, Panova, Veera, Lau, Angelica W.Y., Ashwin, Emily, Seuzaret, Guillaume, Dhenni, Rama, Bhattacharyya, Nayan Deger, Khoo, Weng Hua, Biro, Maté, Mitra, Tanmay, Meyer-Hermann, Michael, Bertolino, Patrick, Tanaka, Masato, Hume, David A., Croucher, Peter I., Brink, Robert, Nguyen, Akira, Bannard, Oliver and Phan, Tri Giang (2023). Apoptotic cell fragments locally activate tingible body macrophages in the germinal center. Cell, 186 (6), 1144-1161. doi: 10.1016/j.cell.2023.02.004 |
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2023 Journal Article Serum CCL2 is associated with visceral adiposity but not fibrosis in patients with Non-alcoholic Fatty Liver Disease (NAFLD)Ferrari-Cestari, Michelle, Okano, Satomi, Patel, Preya J., Horsfall, Leigh U., Keshvari, Sahar, Hume, David A., Williams, Suzanne, Russell, Anthony, Powell, Elizabeth E. and Irvine, Katharine M (2023). Serum CCL2 is associated with visceral adiposity but not fibrosis in patients with Non-alcoholic Fatty Liver Disease (NAFLD). Digestive Diseases, 41 (3), 439-446. doi: 10.1159/000527784 |
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2023 Journal Article Fibrillin-1 and asprosin, novel players in metabolic syndromeSummers, Kim M., Bush, Stephen J., Davis, Margaret R., Hume, David A., Keshvari, Sahar and West, Jennifer A. (2023). Fibrillin-1 and asprosin, novel players in metabolic syndrome. Molecular Genetics and Metabolism, 138 (1) 106979, 106979. doi: 10.1016/j.ymgme.2022.106979 |
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2022 Journal Article Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7)Grapotte, Mathys, Saraswat, Manu, Bessière, Chloé, Menichelli, Christophe, Ramilowski, Jordan A., Severin, Jessica, Hayashizaki, Yoshihide, Itoh, Masayoshi, Tagami, Michihira, Murata, Mitsuyoshi, Kojima-Ishiyama, Miki, Noma, Shohei, Noguchi, Shuhei, Kasukawa, Takeya, Hasegawa, Akira, Suzuki, Harukazu, Nishiyori-Sueki, Hiromi, Frith, Martin C., Abugessaisa, Imad, Aitken, Stuart, Aken, Bronwen L., Alam, Intikhab, Alam, Tanvir, Alasiri, Rami, Alhendi, Ahmad M. N., Alinejad-Rokny, Hamid, Alvarez, Mariano J., Andersson, Robin, Arakawa, Takahiro ... Lecellier, Charles-Henri (2022). Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications, 13 (1) 1200. doi: 10.1038/s41467-022-28758-y |
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2022 Journal Article Microglia states and nomenclature: A field at its crossroadsPaolicelli, Rosa C., Sierra, Amanda, Stevens, Beth, Tremblay, Marie-Eve, Aguzzi, Adriano, Ajami, Bahareh, Amit, Ido, Audinat, Etienne, Bechmann, Ingo, Bennett, Mariko, Bennett, Frederick, Bessis, Alain, Biber, Knut, Bilbo, Staci, Blurton-Jones, Mathew, Boddeke, Erik, Brites, Dora, Brône, Bert, Brown, Guy C., Butovsky, Oleg, Carson, Monica J., Castellano, Bernardo, Colonna, Marco, Cowley, Sally A., Cunningham, Colm, Davalos, Dimitrios, De Jager, Philip L., de Strooper, Bart, Denes, Adam ... Wyss-Coray, Tony (2022). Microglia states and nomenclature: A field at its crossroads. Neuron, 110 (21), 3458-3483. doi: 10.1016/j.neuron.2022.10.020 |
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2022 Journal Article CSF1R as a therapeutic target in bone diseases: obvious but not so simpleHume, David A., Batoon, Lena, Sehgal, Anuj, Keshvari, Sahar and Irvine, Katharine M. (2022). CSF1R as a therapeutic target in bone diseases: obvious but not so simple. Current Osteoporosis Reports, 20 (6), 516-531. doi: 10.1007/s11914-022-00757-4 |
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2022 Journal Article Poincaré profiles of Lie groups and a coarse geometric dichotomyHume, David, Mackay, John M. and Tessera, Romain (2022). Poincaré profiles of Lie groups and a coarse geometric dichotomy. Geometric and Functional Analysis, 32 (5), 1063-1133. doi: 10.1007/s00039-022-00617-4 |
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2022 Journal Article Graphia: a platform for the graph-based visualisation and analysis of high dimensional dataFreeman, Tom C., Horsewell, Sebastian, Patir, Anirudh, Harling-Lee, Josh, Regan, Tim, Shih, Barbara B., Prendergast, James, Hume, David A. and Angus, Tim (2022). Graphia: a platform for the graph-based visualisation and analysis of high dimensional data. PLOS Computational Biology, 18 (7) e1010310, 1-17. doi: 10.1371/journal.pcbi.1010310 |
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2022 Journal Article Contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cellsHume, David A., Offermanns, Stefan and Bonnavion, Remy (2022). Contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells. Immunity, 55 (7), 1139-1140. doi: 10.1016/j.immuni.2022.06.010 |
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2022 Journal Article Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease miceKiani Shabestari, Sepideh, Morabito, Samuel, Danhash, Emma Pascal, McQuade, Amanda, Sanchez, Jessica Ramirez, Miyoshi, Emily, Chadarevian, Jean Paul, Claes, Christel, Coburn, Morgan Alexandra, Hasselmann, Jonathan, Hidalgo, Jorge, Tran, Kayla Nhi, Martini, Alessandra C., Chang Rothermich, Winston, Pascual, Jesse, Head, Elizabeth, Hume, David A., Pridans, Clare, Davtyan, Hayk, Swarup, Vivek and Blurton-Jones, Mathew (2022). Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. Cell Reports, 39 (11) 110961, 1-30. doi: 10.1016/j.celrep.2022.110961 |
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2022 Journal Article Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancerLaviron, Marie, Petit, Maxime, Weber-Delacroix, Eléonore, Combes, Alexis J., Arkal, Arjun Rao, Barthélémy, Sandrine, Courau, Tristan, Hume, David A., Combadière, Christophe, Krummel, Matthew F. and Boissonnas, Alexandre (2022). Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer. Cell Reports, 39 (8) 110865, 1-20. doi: 10.1016/j.celrep.2022.110865 |
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2022 Journal Article A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signallingStables, Jennifer, Green, Emma K., Sehgal, Anuj, Patkar, Omkar L., Keshvari, Sahar, Taylor, Isis, Ashcroft, Maisie E., Grabert, Kathleen, Wollscheid-Lengeling, Evi, Szymkowiak, Stefan, McColl, Barry W., Adamson, Antony, Humphreys, Neil E., Mueller, Werner, Starobova, Hana, Vetter, Irina, Shabestari, Sepideh Kiani, Blurton-Jones, Matthew M., Summers, Kim M., Irvine, Katharine M., Pridans, Clare and Hume, David A. (2022). A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling. Development, 149 (8) dev200237. doi: 10.1242/dev.200237 |
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2022 Journal Article Generation and network analysis of an RNA-seq transcriptional atlas for the ratSummers, Kim M., Bush, Stephen J., Wu, Chunlei and Hume, David A. (2022). Generation and network analysis of an RNA-seq transcriptional atlas for the rat. NAR Genomics and Bioinformatics, 4 (1) lqac017, lqac017. doi: 10.1093/nargab/lqac017 |
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2022 Journal Article Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brainBradford, Barry M., McGuire, Lynne I., Hume, David A., Pridans, Clare and Mabbott, Neil A. (2022). Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain. GLIA, 70 (11), 2169-2187. doi: 10.1002/glia.24244 |
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2022 Journal Article Use of quantitative real‐time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis of horses undergoing small intestinal resectionLisowski, Zofia M., Lefevre, Lucas, Mair, Tim S., Clark, Emily L., Hudson, Neil P. H., Hume, David A. and Pirie, R. Scott (2022). Use of quantitative real‐time PCR to determine the local inflammatory response in the intestinal mucosa and muscularis of horses undergoing small intestinal resection. Equine Veterinary Journal, 54 (1), 52-62. doi: 10.1111/evj.13429 |
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2022 Journal Article Letter to the editor: Questioning the existence of Aif1+, Csf1r+ mesenchymal stem cellsHume, David A. (2022). Letter to the editor: Questioning the existence of Aif1+, Csf1r+ mesenchymal stem cells. Hepatology, 78 (2), n/a-n/a. doi: 10.1002/hep.32809 |
