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2020 Journal Article Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domesticationDutta, Prasun, Talenti, Andrea, Young, Rachel, Jayaraman, Siddharth, Callaby, Rebecca, Jadhav, Santosh Kumar, Dhanikachalam, Velu, Manikandan, Mayakannan, Biswa, Bhim B., Low, Wai Y., Williams, John L., Cook, Elizabeth, Toye, Phil, Wall, Eileen, Djikeng, Appolinaire, Marshall, Karen, Archibald, Alan L., Gokhale, Suresh, Kumar, Satish, Hume, David A. and Prendergast, James G. D. (2020). Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication. Nature Communications, 11 (1) 4739. doi: 10.1038/s41467-020-18550-1 |
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2020 Journal Article Poorly connected groupsHume, David and Mackay, John M. (2020). Poorly connected groups. Proceedings of the American Mathematical Society, 148 (11), 4653-4664. doi: 10.1090/proc/15128 |
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2020 Journal Article Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte systemSummers, Kim M., Bush, Stephen J. and Hume, David A. (2020). Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. PLoS Biology, 18 (10) e3000859, 1-45. doi: 10.1371/journal.pbio.3000859 |
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2020 Journal Article Measurement of serum Interleukin 34 (IL-34) and correlation with severity and pruritus scores in client-owned dogs with atopic dermatitisGow, Deborah J., Jackson, Hilary, Forsythe, Peter, Nuttall, Tim, Gow, Adam G., Mellanby, Richard J. and Hume, David A. (2020). Measurement of serum Interleukin 34 (IL-34) and correlation with severity and pruritus scores in client-owned dogs with atopic dermatitis. Veterinary Dermatology, 31 (5), 359-e94. doi: 10.1111/vde.12873 |
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2020 Journal Article Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries)Tsang, Hiu-Gwen, Clark, Emily L., Markby, Greg R., Bush, Stephen J., Hume, David A., Corcoran, Brendan M., MacRae, Vicky E. and Summers, Kim M. (2020). Expression of calcification and extracellular matrix genes in the cardiovascular system of the healthy domestic sheep (Ovis aries). Frontiers in Genetics, 11 919. doi: 10.3389/fgene.2020.00919 |
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2020 Journal Article Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tractLisowski, Zofia M., Sauter, Kristin A., Waddell, Lindsey A., Hume, David A., Pirie, R. Scott and Hudson, Neil P.H. (2020). Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tract. Veterinary Immunology and Immunopathology, 226 110073, 110073. doi: 10.1016/j.vetimm.2020.110073 |
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2020 Journal Article Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophagesBush, Stephen J., McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Clark, Emily L., Young, Rachel, Pridans, Clare, Prendergast, James G. D., Summers, Kim M. and Hume, David A. (2020). Species-specificity of transcriptional regulation and the response to lipopolysaccharide in mammalian macrophages. Frontiers in Cell and Developmental Biology, 8 661. doi: 10.3389/fcell.2020.00661 |
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2020 Journal Article The transcriptional network that controls growth arrest and macrophage differentiation in the human myeloid leukemia cell line THP-1Gažová, Iveta, Lefevre, Lucas, Bush, Stephen J., Clohisey, Sara, Arner, Erik, de Hoon, Michiel, Severin, Jessica, van Duin, Lucas, Andersson, Robin, Lengeling, Andreas, Hume, David A. and Summers, Kim M. (2020). The transcriptional network that controls growth arrest and macrophage differentiation in the human myeloid leukemia cell line THP-1. Frontiers in Cell and Developmental Biology, 8 498. doi: 10.3389/fcell.2020.00498 |
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2020 Journal Article An improved pig reference genome sequence to enable pig genetics and genomics researchWarr, Amanda, Affara, Nabeel, Aken, Bronwen, Beiki, Hamid, Bickhart, Derek M., Billis, Konstantinos, Chow, William, Eory, Lel, Finlayson, Heather A., Flicek, Paul, Girón, Carlos G., Griffin, Darren K., Hall, Richard, Hannum, Greg, Hourlier, Thibaut, Howe, Kerstin, Hume, David A., Izuogu, Osagie, Kim, Kristi, Koren, Sergey, Liu, Haibou, Manchanda, Nancy, Martin, Fergal J., Nonneman, Dan J., O'Connor, Rebecca E., Phillippy, Adam M., Rohrer, Gary A., Rosen, Benjamin D., Rund, Laurie A. ... Archibald, Alan L. (2020). An improved pig reference genome sequence to enable pig genetics and genomics research. GigaScience, 9 (6) GIAA051. doi: 10.1093/gigascience/giaa051 |
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2020 Journal Article Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disordersWittenberg, Gayle M., Stylianou, Annie, Zhang, Yun, Sun, Yu, Gupta, Ashutosh, Jagannatha, P. S., Wang, Dai, Hsu, Benjamin, Curran, Mark E., Khan, Shahid, Vértes, Petra E., Cardinal, Rudolf, Richardson, Sylvia, Leday, Gwenael, Freeman, Tom, Hume, David, Regan, Tim, Wu, Zhaozong, Pariante, Carmine, Cattaneo, Annamaria, Zunszain, Patricia, Borsini, Alessandra, Stewart, Robert, Chandran, David, Carvalho, Livia, Bell, Joshua, Souza-Teodoro, Luis Henrique, Perry, Hugh, Harrison, Neil ... MRC ImmunoPsychiatry Consortium (2020). Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders. Molecular Psychiatry, 25 (6), 1275-1285. doi: 10.1038/s41380-019-0471-8 |
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2020 Journal Article Comprehensive characterization of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequencesClohisey, Sara, Parkinson, Nicholas, Wang, Bo, Bertin, Nicolas, Wise, Helen, Tomoiu, Andru, Summers, Kim M., Hendry, Ross W., Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Digard, Paul, Hume, David A. and Baillie, J. Kenneth (2020). Comprehensive characterization of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequences. Journal of Virology, 94 (10) e01720-19. doi: 10.1128/JVI.01720-19 |
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2020 Journal Article Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune systemWu, Zhiguang, Harne, Rakhi, Chintoan-Uta, Cosmin, Hu, Tuan-Jun, Wallace, Robert, MacCallum, Amanda, Stevens, Mark P., Kaiser, Pete, Balic, Adam and Hume, David A. (2020). Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system. Developmental and Comparative Immunology, 105 103586, 103586. doi: 10.1016/j.dci.2019.103586 |
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2020 Journal Article Poincaré profiles of groups and spacesHume, David, Mackay, John M. and Tessera, Romain (2020). Poincaré profiles of groups and spaces. Revista Matematica Iberoamericana, 36 (6), 1835-1886. doi: 10.4171/RMI/1184 |
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2020 Journal Article Functional annotation of the transcriptome of the pig, Sus scrofa, based upon network analysis of an RNAseq transcriptional atlasSummers, Kim M., Bush, Stephen J., Wu, Chunlei, Su, Andrew I., Muriuki, Charity, Clark, Emily L., Finlayson, Heather A., Eory, Lel, Waddell, Lindsey A., Talbot, Richard, Archibald, Alan L. and Hume, David A. (2020). Functional annotation of the transcriptome of the pig, Sus scrofa, based upon network analysis of an RNAseq transcriptional atlas. Frontiers in Genetics, 10 1355. doi: 10.3389/fgene.2019.01355 |
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2020 Journal Article Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisationWragg, D., Liu, Q., Lin, Z., Riggio, V., Pugh, C. A., Beveridge, A. J., Brown, H., Hume, D. A., Harris, S. E., Deary, I. J., Tenesa, A. and Prendergast, J. G.D. (2020). Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation. Nature Communications, 11 (1) 343. doi: 10.1038/s41467-019-13762-6 |
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2020 Journal Article The geometry of generalized loxodromic elementsAbbott, Carolyn R. and Hume, David (2020). The geometry of generalized loxodromic elements. Annales de l'Institut Fourier, 70 (4), 1689-1713. doi: 10.5802/AIF.3379 |
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2019 Journal Article Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheepBanos, Georgios, Clark, Emily L., Bush, Stephen J., Dutta, Prasun, Georgios Bramis, D., Arsenos, Georgios, Hume, David A. and Psifidi, Androniki (2019). Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep. PLoS One, 14 (11) e0214346, e0214346. doi: 10.1371/journal.pone.0214346 |
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2019 Journal Article Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regionsHalachev, Mihail, Meynert, Alison, Taylor, Martin S., Vitart, Veronique, Kerr, Shona M., Klaric, Lucija, Consortium, S. G.P., Aitman, Timothy J., Haley, Chris S., Prendergast, James G., Pugh, Carys, Hume, David A., Harris, Sarah E., Liewald, David C., Deary, Ian J., Semple, Colin A. and Wilson, James F. (2019). Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions. PLoS Genetics, 15 (11) e1008480, e1008480. doi: 10.1371/journal.pgen.1008480 |
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2019 Journal Article Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickensFreem, Lucy, Summers, Kim M., Gheyas, Almas A., Psifidi, Androniki, Boulton, Kay, MacCallum, Amanda, Harne, Rakhi, O’Dell, Jenny, Bush, Stephen J. and Hume, David A. (2019). Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickens. Frontiers in Genetics, 10 1032. doi: 10.3389/fgene.2019.01032 |
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2019 Journal Article A mini-atlas of gene expression for the domestic goat (Capra hircus)Muriuki, Charity, Bush, Stephen J., Salavati, Mazdak, McCulloch, Mary E.B., Lisowski, Zofia M., Agaba, Morris, Djikeng, Appolinaire, Hume, David A. and Clark, Emily L. (2019). A mini-atlas of gene expression for the domestic goat (Capra hircus). Frontiers in Genetics, 10 1080, 1080. doi: 10.3389/fgene.2019.01080 |
