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2019

Journal Article

Relatively hyperbolic groups with fixed peripherals

Cordes, Matthew and Hume, David (2019). Relatively hyperbolic groups with fixed peripherals. Israel Journal of Mathematics, 230 (1), 443-470. doi: 10.1007/s11856-019-1830-5

Relatively hyperbolic groups with fixed peripherals

2019

Journal Article

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

Prendergast, James G D, Pugh, Carys, Harris, Sarah E., Hume, David A., Deary, Ian J. and Beveridge, Allan (2019). Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution. Genome Biology and Evolution, 11 (3), 759-775. doi: 10.1093/gbe/evz014

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

2019

Journal Article

Causes and consequences of innate immune dysfunction in cirrhosis

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Causes and consequences of innate immune dysfunction in cirrhosis. Frontiers in Immunology, 10 (FEB) 293, 293. doi: 10.3389/fimmu.2019.00293

Causes and consequences of innate immune dysfunction in cirrhosis

2019

Journal Article

Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R

Hu, Tuanjun, Wu, Zhiguang, Bush, Stephen J., Freem, Lucy, Vervelde, Lonneke, Summers, Kim M., Hume, David A., Balic, Adam and Kaiser, Pete (2019). Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R. The Journal of Immunology, 202 (4), 1186-1199. doi: 10.4049/jimmunol.1800504

Characterization of subpopulations of chicken mononuclear phagocytes that express TIM4 and CSF1R

2019

Journal Article

The mononuclear phagocyte system: the relationship between monocytes and macrophages

Hume, David A., Irvine, Katharine M. and Pridans, Clare (2019). The mononuclear phagocyte system: the relationship between monocytes and macrophages. Trends in Immunology, 40 (2), 98-112. doi: 10.1016/j.it.2018.11.007

The mononuclear phagocyte system: the relationship between monocytes and macrophages

2019

Journal Article

Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression

Bush, Stephen J., McCulloch, Mary E. B., Muriuki, Charity, Salavati, Mazdak, Davis, Gemma M., Farquhar, Iseabail L., Lisowski, Zofia M., Archibald, Alan L., Hume, David A. and Clark, Emily L. (2019). Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression. G3: Genes, Genomes, Genetics, 9 (2), 359-373. doi: 10.1534/g3.118.200810

Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood reveals strong developmental stage specific gene expression

2019

Journal Article

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity

Low, Wai Yee, Tearle, Rick, Bickhart, Derek M., Rosen, Benjamin D., Kingan, Sarah B., Swale, Thomas, Thibaud-Nissen, Françoise, Murphy, Terence D., Young, Rachel, Lefevre, Lucas, Hume, David A., Collins, Andrew, Ajmone-Marsan, Paolo, Smith, Timothy P. L. and Williams, John L. (2019). Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity. Nature Communications, 10 (1) 260. doi: 10.1038/s41467-018-08260-0

Chromosome-level assembly of the water buffalo genome surpasses human and goat genomes in sequence contiguity

2019

Journal Article

Negative curvature in graphical small cancellation groups

Arzhantseva, Goulnara N., Cashen, Christopher H., Gruber, Dominik and Hume, David (2019). Negative curvature in graphical small cancellation groups. Groups, Geometry, and Dynamics, 13 (2), 579-632. doi: 10.4171/GGD/498

Negative curvature in graphical small cancellation groups

2019

Journal Article

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

Irvine, Katharine Margaret, Ratnasekera, Isanka, Powell, Elizabeth E. and Hume, David Arthur (2019). Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293). Frontiers in Immunology, 10 (APR) 818, 818. doi: 10.3389/fimmu.2019.00818

Corrigendum: Causes and consequences of innate immune dysfunction in cirrhosis (Frontiers in Immunology (2019) 10 (293) DOI: 10.3389/fimmu.2019.00293)

2019

Journal Article

A gene expression atlas of the domestic water buffalo (Bubalus bubalis)

Young, Rachel, Lefevre, Lucas, Bush, Stephen J., Joshi, Akshay, Singh, Salam H., Jadhav, Santosh K., Lisowski, Zofia M., Iamartino, Daniela, Summers, Kim M., Williams, John L., Archibald, Alan L., Gokhale, Suresh, Kumar, Satish and Hume, David A. (2019). A gene expression atlas of the domestic water buffalo (Bubalus bubalis). Frontiers in Genetics, 10 (JUN) 668. doi: 10.3389/fgene.2019.00668

A gene expression atlas of the domestic water buffalo (Bubalus bubalis)

2018

Journal Article

A chicken bioreactor for efficient production of functional cytokines

Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew C. and Sang, Helen M. (2018). A chicken bioreactor for efficient production of functional cytokines. BMC Biotechnology, 18 (1) 82. doi: 10.1186/s12896-018-0495-1

A chicken bioreactor for efficient production of functional cytokines

2018

Journal Article

Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken

Boulton, Kay, Nolan, Matthew J., Wu, Zhiguang, Riggio, Valentina, Matika, Oswald, Harman, Kimberley, Hocking, Paul M., Bumstead, Nat, Hesketh, Pat, Archer, Andrew, Bishop, Stephen C., Kaiser, Pete, Tomley, Fiona M., Hume, David A., Smith, Adrian L., Blake, Damer P. and Psifidi, Androniki (2018). Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken. Frontiers in Genetics, 9 528, 528. doi: 10.3389/fgene.2018.00528

Dissecting the genomic architecture of resistance to Eimeria maxima parasitism in the chicken

2018

Journal Article

Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis

Boulton, Kay, Nolan, Matthew J., Wu, Zhiguang, Psifidi, Androniki, Riggio, Valentina, Harman, Kimberley, Bishop, Stephen C., Kaiser, Pete, Abrahamsen, Mitchell S., Hawken, Rachel, Watson, Kellie A., Tomley, Fiona M., Blake, Damer P. and Hume, David A. (2018). Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis. Genetics Selection Evolution, 50 (1) 63, 63. doi: 10.1186/s12711-018-0433-7

Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis

2018

Journal Article

Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors

Nirmal, Ajit J., Regan, Tim, Shih, Barbara B., Hume, David A., Sims, Andrew H. and Freeman, Tom C. (2018). Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors. Cancer Immunology Research, 6 (11), 1388-1400. doi: 10.1158/2326-6066.CIR-18-0342

Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors

2018

Journal Article

ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages

Waddell, Lindsey A., Lefevre, Lucas, Bush, Stephen J., Raper, Anna, Young, Rachel, Lisowski, Zofia M., McCulloch, Mary E.B., Muriuki, Charity, Sauter, Kristin A., Clark, Emily L., Irvine, Katharine M., Pridans, Clare, Hope, Jayne C. and Hume, David A. (2018). ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages. Frontiers in Immunology, 9 (OCT) 2246. doi: 10.3389/fimmu.2018.02246

ADGRE1 (EMR1, F4/80) is a rapidly-evolving gene expressed in mammalian monocyte-macrophages

2018

Journal Article

Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus

Pridans, Clare, Raper, Anna, Davis, Gemma M., Alves, Joana, Sauter, Kristin A., Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J., Clohisey, Sara, Bush, Stephen J, Rojo, Rocío, Lisowski, Zofia M., Wallace, Robert, Grabert, Kathleen, Upton, Kyle R., Tsai, Yi Ting, Brown, Deborah, Smith, Lee B., Summers, Kim M., Mabbott, Neil A., Piccardo, Pedro, Cheeseman, Michael T., Burdon, Tom and Hume, David A. (2018). Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus. Journal of Immunology, 201 (9), 2683-2699. doi: 10.4049/jimmunol.1701783

Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus

2018

Journal Article

Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity

Brown, S. M., Bush, S. J., Summers, K. M., Hume, D. A. and Lawrence, A. B. (2018). Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity. Behavioural Brain Research, 350, 6-15. doi: 10.1016/j.bbr.2018.05.015

Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity

2018

Journal Article

The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

Scott, Charlotte L., T'Jonck, Wouter, Martens, Liesbet, Todorov, Helena, Sichien, Dorine, Soen, Bieke, Bonnardel, Johnny, De Prijck, Sofie, Vandamme, Niels, Cannoodt, Robrecht, Saelens, Wouter, Vanneste, Bavo, Toussaint, Wendy, De Bleser, Pieter, Takahashi, Nozomi, Vandenabeele, Peter, Henri, Sandrine, Pridans, Clare, Hume, David A., Lambrecht, Bart N., De Baetselier, Patrick, Milling, Simon W. F., Van Ginderachter, Jo A., Malissen, Bernard, Berx, Geert, Beschin, Alain, Saeys, Yvan and Guilliams, Martin (2018). The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages. Immunity, 49 (2), 312-+. doi: 10.1016/j.immuni.2018.07.004

The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

2018

Journal Article

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken

Bush, Stephen J., Freem, Lucy, MacCallum, Amanda J., O'Dell, Jenny, Wu, Chunlei, Afrasiabi, Cyrus, Psifidi, Androniki, Stevens, Mark P., Smith, Jacqueline, Summers, Kim M. and Hume, David A. (2018). Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken. BMC Genomics, 19 (1) 594. doi: 10.1186/s12864-018-4972-7

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken

2018

Journal Article

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment