Overview
Background
Dr. Mohd Hafiz Abdul-Aziz is a National Health and Medical Research Council (NHMRC) Emerging Leadership Fellow EL2 (2026) and Clinical Research Pharmacist at the University of Queensland Centre for Clinical Research (UQCCR), Australia. He currently leads the Clinical Dosing Studies and Knowledge Translation Workstream within the Antimicrobial Optimisation Group and the Centre for Research Excellence for Personalising Antimicrobial Dosing to Reduce Resistance (CRE RESPOND) at UQCCR. Dr. Abdul-Aziz holds a Bachelor of Pharmacy (IIUM) and a Master of Clinical Pharmacy (UKM) from Malaysia and completed his PhD at the University of Queensland in 2016. His doctoral thesis focused on pharmacokinetic/pharmacodynamic (PK/PD)-optimised beta-lactam dosing in critically ill patients.
As a clinical pharmacist with a strong interest in clinical research, Dr. Abdul-Aziz is particularly focused on multi-centre and multi-national collaborations. His current research program aims to develop innovative methods for optimising antimicrobial dosing and delivery to improve patient outcomes in the ICU. His current areas of interest include: (1) antimicrobial pharmacokinetics/pharmacodynamics (PK/PD); (2) antimicrobial dosing in special patient population groups (e.g. critically ill, pneumonia, extracorporeal membrane oxygenation (ECMO), renal replacement therapy (RRT) patients; (3) prolonged infusions of beta-lactam antibiotics; (4) antimicrobial therapeutic drug monitoring (TDM); (5) ex-vivo pharmacokinetic ECMO and RRT model experiments; (6) model-informed precision antimicrobial dosing; and (7) multi-centre population pharmacokinetic studies. He has authored over 100 peer-reviewed papers and book chapters in this research area. His publications have been cited more than 5000 times. He has extensive experience in designing and conducting multi-national clinical pharmacokinetic studies in the ICU. Over the past five years, he has led or coordinated eight multi-national antimicrobial pharmacokinetic studies, including the ASAP ECMO, BLING 3, BLING 3 PK/PD, and PNEUDOS studies.
Dr. Abdul-Aziz is a Fellow of the International Society of Antimicrobial Chemotherapy (ISAC) and currently serves as the Chair of the Infections in the ICU and Sepsis Working Group of ISAC, and a member of ECMOPharmNet, a multidisciplinary network of ECMO pharmacology experts. He maintains active collaborations with more than 100 researchers across 36 countries.
Information for Potential Students
Dr. Abdul-Aziz welcomes expressions of interest from prospective postgraduate students. Interested applicants are encouraged to contact him via email to discuss potential research opportunities. Please include an up-to-date CV and a brief research proposal outlining the project you wish to undertake. Dr. Abdul-Aziz is also open to developing projects that address research questions specific to your clinical practice, particularly those related to optimising antimicrobial dosing and delivery.
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Research interests
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Antimicrobial pharmacokinetics/pharmacodynamics (PK/PD) in critically ill patients
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Antimicrobial therapeutic drug monitoring (TDM) in the intensive care unit (ICU)
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Ex-vivo pharmacokinetic ECMO and RRT model experiments
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Antimicrobial dosing in special patient population groups (e.g. critically ill, pneumonia, extracorporeal membrane oxygenation (ECMO), renal replacement therapy (RRT) patients
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Prolonged infusions of beta-lactam antibiotics in critically ill patients
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Model-informed precision antimicrobial dosing in the intensive care unit (ICU)
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Multi-centre population pharmacokinetic studies
Works
Search Professor Hafiz Abdul-Aziz’s works on UQ eSpace
1986
Journal Article
FESTSCHRIFT IN HONOR OF FERGUSON,CHARLES,A. - INTRODUCTION
FISHMAN, JA, ABDULAZIZ, MH, CLYNE, M, KRISHNAMURTI, B and TABOURETKELLER, A (1986). FESTSCHRIFT IN HONOR OF FERGUSON,CHARLES,A. - INTRODUCTION. International Journal of the Sociology of Language (62), 5-9.
Funding
Current funding
Past funding
Supervision
Availability
- Dr Hafiz Abdul-Aziz is:
- Available for supervision
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Available projects
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Extended versus continuous infusion of beta-lactam antibiotics in critically ill patients with sepsis: a randomised controlled trial of PK/PD target attainment and clinical outcomes
This PhD project will compare extended and continuous infusion strategies for beta-lactam antibiotics in critically ill patients with sepsis or septic shock. The project would suit an international candidate with access to a suitable clinical site outside Australia preferably through their home institution or existing clinical network. The candidate would be expected to help facilitate local ethics approval, patient recruitment, and data and/or sample collection, with supervision and methodological support provided by the Australian supervisory team.
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Optimising beta-lactam antibiotic dosing in acute kidney injury: a randomised controlled trial of early versus delayed dose adjustment strategies
This PhD project will evaluate beta-lactam antibiotic dosing strategies in patients with acute kidney injury, focusing on whether early versus delayed dose adjustment improves antibiotic exposure and patient outcomes. The project would suit an international candidate with access to a suitable clinical site outside Australia preferably through their home institution or existing clinical network. The candidate would be expected to help facilitate local ethics approval, patient recruitment, and data and/or sample collection, with supervision and methodological support provided by the Australian supervisory team.
Supervision history
Current supervision
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Master Philosophy
Determining bEta-lactam Exposure targets in Patients with deep-seated infections.
Principal Advisor
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Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Associate Advisor
Other advisors: Professor Jason Roberts
Completed supervision
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2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Associate Advisor
Other advisors: Dr Fekade Sime, Professor Jason Roberts
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2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Associate Advisor
Other advisors: Emeritus Professor Jeffrey Lipman, Professor Jason Roberts
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2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Associate Advisor
Other advisors: Professor Kiran Shekar, Professor Jason Roberts
Media
Enquiries
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