Overview
Background
Dr Haolu Wang currently is a Medical Registrar and Basic Physician Trainee with the Royal Australasian College of Physicians - The Prince Charles Hospital and Redcliffe Hospital (Northside) Rotation. He is also an Honorary Research Fellow in the joint liver cancer research program of Frazer Institute, The University of Queensland and Gallipoli Medical Research Foundation. Dr Wang received his Bachelor of Medicine and Master of Surgery qualifications from Shanghai Jiao Tong University School of Medicine. He was awarded his PhD in Clinical Medicine from The University of Queensland. Dr Wang has worked as a Medical Officer at Renji Hospital, Shanghai Jiao Tong University School of Medicine and as a Researcher Officer at Frazer Institute, The University of Queensland.
Dr Wang has authored over 30 publications of clinical and translational research in liver diseases, including Hepatology, Theranostics, Int J Cancer, J Exp Clin Cancer Res and Pharmacol Ther. His standing in this field is reflected by awards from Australian National Health and Medical Research Council, United European Gastroenterology, European Microscopy Congress, The University of Queensland, Frazer Family Foundation and Shanghai Jiao Tong University.
Availability
- Dr Haolu Wang is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Clinical Medicine, Shanghai Jiao Tong University
- Masters (Research) of Clinical Surgery, Shanghai Jiao Tong University
- Doctor of Philosophy of Medicine (Research), The University of Queensland
Research impacts
As a translational researcher, Dr Wang has made contributions to curative efficacy evaluation in liver diseases. He real-time imaged hepatic vascular integrity and revealed the underlying molecular mechanism to predict treatment outcomes in drug-induced liver injury (Sci Rep. 2017, Theranostics. 2020). Using this real-time imaging platform, he was the first to develop modelling approaches to optimise dosing regimens of therapeutic stem cells against liver diseases (Curr Protoc Stem Cell Biol. 2017; Sci Rep. 2016).
As a clinical researcher, he evaluated current treatment efficacy of liver cancer (Eur J Surg Oncol. 2022) and primary sclerosing cholangitis (Pharmacol Ther. 2022), which has been cited by 2023 Practice Guidance of American Association for the Study of Liver Diseases.
Works
Search Professor Haolu Wang’s works on UQ eSpace
2017
Conference Publication
In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe
Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2242978
2017
Book Chapter
Hepatic metabolism in liver health and disease
Liu, X., Wang, H., Liang, X. and Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. Liver Pathophysiology: Therapies and Antioxidants. (pp. 391-400) edited by Pablo Muriel. Cambridge, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-804274-8.00030-8
2017
Conference Publication
Non-invasive assessment of the liver using imaging
Thorling (Thompson), Camilla, Wang, Haolu, Liu, Xin, Liang, Xiaowen, Crawford, Darrell H. G. and Roberts, Michael S. (2017). Non-invasive assessment of the liver using imaging. SPIE BioPhotonics Australasia Conference, Adelaide, SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: International Society for Optical Engineering. doi: 10.1117/12.2242883
2017
Conference Publication
Quantitative optical imaging of paracetamol-induced metabolism changes in the liver
Liang, Xiaowen, Wang, Haolu, Liu, Xin and Roberts, Michael (2017). Quantitative optical imaging of paracetamol-induced metabolism changes in the liver. SPIE BioPhotonics Australasia, Adelaide, SA, Australia, 17 - 19 October 2016. Bellingham, WA, United States: International Society for Optical Engineering. doi: 10.1117/12.2242962
2016
Journal Article
MDCT assessment of resectability in hilar cholangiocarcinoma
Ni, Qihong, Wang, Haolu, Zhang, Yunhe, Qian, Lijun, Chi, Jiachang, Liang, Xiaowen, Chen, Tao and Wang, Jian (2016). MDCT assessment of resectability in hilar cholangiocarcinoma. Abdominal Radiology, 42 (3), 1-10. doi: 10.1007/s00261-016-0943-0
2016
Journal Article
Late-onset deep mesh infection: a study of eight cases detected from 2666 consecutive patients with abdominal wall hernia repairs
Chen, Tao, Zhang, Yun-He, Wang, Hao-Lu, Chen, Wei and Wang, Jian (2016). Late-onset deep mesh infection: a study of eight cases detected from 2666 consecutive patients with abdominal wall hernia repairs. Chinese Medical Journal, 129 (15), 1870-1872. doi: 10.4103/0366-6999.186651
2016
Journal Article
Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy
Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2016). Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of Biophotonics, 10 (1), 46-60. doi: 10.1002/jbio.201600083
2016
Journal Article
Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones
Macklin, Rebecca, Wang, Haolu, Loo, Dorothy, Martin, Sally, Cumming, Andrew, Cai, Na, Lane, Rebecca, Ponce, Natalia Saenz, Topkas, Eleni, Inder, Kerry, Saunders, Nicholas A. and Endo-Munoz, Liliana (2016). Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones. Oncotarget, 7 (28), 43570-43587. doi: 10.18632/oncotarget.9781
2016
Journal Article
Emergency inguinal hernia repair under local anesthesia: a 5-year experience in a teaching hospital
Chen, Tao, Zhang, Yunhe, Wang, Haolu, Ni, Qihong, Yang, Linhua, Li, Qiwei and Wang, Jian (2016). Emergency inguinal hernia repair under local anesthesia: a 5-year experience in a teaching hospital. BMC Anesthesiology, 16 (1) 17, 17-17. doi: 10.1186/s12871-016-0185-2
2016
Journal Article
A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells
Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 (1) 22293, e22293.1-e22293.12. doi: 10.1038/srep22293
2016
Journal Article
Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles
Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 (2), 939-945. doi: 10.1021/acs.nanolett.5b03854
2016
Journal Article
Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney
Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016). Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 (1), 387-395. doi: 10.1021/acsnano.5b05066
2015
Journal Article
Clinicopathological characteristics of gynecological cancer associated with hypoxia-inducible factor 1α expression: a meta-analysis including 6,612 subjects
Jin, Yue, Wang, Haolu, Ma, Xiaowei, Liang, Xiaowen, Liu, Xin and Wang, Yu (2015). Clinicopathological characteristics of gynecological cancer associated with hypoxia-inducible factor 1α expression: a meta-analysis including 6,612 subjects. PLoS ONE, 10 (5) e0127229, e0127229. doi: 10.1371/journal.pone.0127229
2015
Journal Article
Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging
Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780
2015
Journal Article
Diagnostic imaging and therapeutic application of nanoparticles targeting the liver
Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 (6), 939-958. doi: 10.1039/C4TB01611D
2015
Journal Article
Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition
Thorling C.A., Jin L., Weiss M., Crawford D., Liu X., Burczynski F.J., Liu D., Wang H. and Roberts M.S. (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug Metabolism and Disposition, 43 (1), 154-162. doi: 10.1124/dmd.114.060848
2014
Journal Article
Pathological and prognostic significance of hypoxia-inducible factor 1α expression in epithelial ovarian cancer: a meta-analysis
Jin, Yue, Wang, Haolu, Liang, Xiaowen, Ma, Jun and Wang, Yu (2014). Pathological and prognostic significance of hypoxia-inducible factor 1α expression in epithelial ovarian cancer: a meta-analysis. Tumor Biology, 35 (8), 8149-8159. doi: 10.1007/s13277-014-2059-x
2014
Journal Article
Evaluation of the POSSUM, P-POSSUM and E-PASS scores in the surgical treatment of hilar cholangiocarcinoma
Wang, Hui, Wang, Haolu, Chen, Tao, Liang, Xiaowen, Song, Yanyan and Wang, Jian (2014). Evaluation of the POSSUM, P-POSSUM and E-PASS scores in the surgical treatment of hilar cholangiocarcinoma. World Journal of Surgical Oncology, 12 (1) 191. doi: 10.1186/1477-7819-12-191
2014
Journal Article
Bacteria in hernia sac: an important risk fact for surgical site infection after incarcerated hernia repair
Yang, L., Wang, H., Liang, X., Chen, T., Chen, W., Song, Y. and Wang, J. (2014). Bacteria in hernia sac: an important risk fact for surgical site infection after incarcerated hernia repair. Hernia, 19 (2), 279-283. doi: 10.1007/s10029-014-1275-z
Funding
Past funding
Supervision
Availability
- Dr Haolu Wang is:
- Available for supervision
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Supervision history
Completed supervision
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Principal Advisor
Other advisors: Emeritus Professor Michael Roberts, Dr Kim Bridle, Dr Xiaowen Liang
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Associate Advisor
Other advisors: Dr Xin Liu, Emeritus Professor Michael Roberts
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Emeritus Professor Michael Roberts, Dr Xiaowen Liang
Media
Enquiries
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