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Dr Leon Hugo
Dr

Leon Hugo

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Overview

Background

Dr Leon Hugo is a medical entomologist conducting research into the biology of mosquitoes, host-parasite interactions and the development of novel control strategies against arthropod-borne viruses (arboviruses). Dr Hugo is an Honorary Associate Professor through the School of Biomedical Sciences and is also the Academic Lead of the Mosquito Control Laboratory at QIMR Berghofer medical research institute, Brisbane. Dr Hugo has developed and applied experimental mosquito models of arbovirus infection for over 15 years to establish the risk of arbovirus transmission in Australia and new biological controls. Dr Hugo works with physical containment/biosecurity level (PC/BSL) 2 and 3 arboviruses, including dengue, Zika, Japanese encephalitis and chikungunya viruses and performs fundamental research on Wolbachia bacteria and Insect-specific virus (ISV) microbial control agents. Dr Hugo has published 60+ research articles with over 160 collaborators, from academic, medical, government and corporate sectors, across 18 countries. Topic areas his publications have had greatest impact were Japanese Encephalitis and Socioeconomic Impact, Wolbachia’s Role in Mosquito Population Replacement and Insecticide Resistance Mechanisms in Aedes aegypti.

Dr Hugo’s team maintains a living library of native and exotic mosquito species and conducts infection and transmission studies in state-of-the-art PC2 and PC3 insectaries. Research themes including mosquito vector competence, climate change impacts on mosquito-borne disease transmission risk, mosquito and arbovirus surveillance and genomics and novel control strategies, including biological control and the use of endectocides.

Availability

Dr Leon Hugo is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Research impacts

Seven of Dr Hugo's publications have attracted over 40 citations in policy documents across 8+ countries from agencies including the WHO, State of Hawaii and the OECD.

Works

Search Professor Leon Hugo’s works on UQ eSpace

69 works between 2003 and 2025

41 - 60 of 69 works

2018

Journal Article

Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti

Asad, Sultan, Hussain, Mazhar, Hugo, Leon, Osei-Amo, Solomon, Zhang, Guangmei, Watterson, Daniel and Asgari, Sassan (2018). Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti. PLoS Neglected Tropical Diseases, 12 (4) e0006405, e0006405. doi: 10.1371/journal.pntd.0006405

Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti

2018

Conference Publication

Characterization of Wolbachia infections from native Australian mosquito vectors

Wu, Chen, Fernandes, Jill, Devine, Greg and Hugo, Leon (2018). Characterization of Wolbachia infections from native Australian mosquito vectors. 67th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTHM), New Orleans, Los Angeles, 28 October - 1 November 2018. Deerfield, IL, United States: American Society of Tropical Medicine and Hygiene.

Characterization of Wolbachia infections from native Australian mosquito vectors

2018

Conference Publication

Relative vector competence of Aedes aegypti and Ae. albopictus for an epidemic strain of Zika virus under simulated field conditions

Hugo, Leon, Stassen, Liesel, Devine, Gregor and Frentiu, Francesca (2018). Relative vector competence of Aedes aegypti and Ae. albopictus for an epidemic strain of Zika virus under simulated field conditions. 67th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTHM), New Orleans, LA, United States, 28 October - 1 November 2018. Arlington, VA, United States: American Society of Tropical Medicine and Hygiene.

Relative vector competence of Aedes aegypti and Ae. albopictus for an epidemic strain of Zika virus under simulated field conditions

2018

Conference Publication

A novel quantitative PCR assay for the detection of Ross River virus

Kuzma, Rebecca, Grant, Jessica, Pilotte, Nils, Hugo, Leon, Devine, Gregor, Lau, Colleen and Williams, Steven (2018). A novel quantitative PCR assay for the detection of Ross River virus. 67th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTHM), New Orleans, LA, United States, 28 October - 1 November 2018. Arlington, VA, United States: American Society of Tropical Medicine and Hygiene.

A novel quantitative PCR assay for the detection of Ross River virus

2017

Conference Publication

Detection of mammalian antibodies against Ross River virus in mosquito blood meals and potential for arbovirus surveillance

Hugo, Leon E., Darbro, Jonathan, Kho, Elise, Gyawali, Narayan and Devine, Greg (2017). Detection of mammalian antibodies against Ross River virus in mosquito blood meals and potential for arbovirus surveillance. 65th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, GA, United States, 13 - 16 November 2016. Arlington, VA, United States: American Society of Tropical Medicine and Hygiene.

Detection of mammalian antibodies against Ross River virus in mosquito blood meals and potential for arbovirus surveillance

2017

Journal Article

De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case

Setoh, Yin Xiang, Prow, Natalie A., Peng, Nias, Hugo, Leon E., Devine, Gregor, Hazlewood, Jessamine E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case. mSphere, 2 (3) e00190-17, 1-11. doi: 10.1128/mSphereDirect.00190-17

De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case

2017

Conference Publication

Next generation mosquito surveillance technique: the near infra-red spectroscopy

Sikulu-Lord, Maggy, Wirtz, Robert, Hugo, Leon, Ulrich, Jill, Devine, Gregor, Masabho, Milali P., de Freitas, Rafael and Dowell, Floyd (2017). Next generation mosquito surveillance technique: the near infra-red spectroscopy. 66th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Baltimore, Maryland USA, 05-09 November 2017. Deerfield, IL United States: American Society of Tropical Medicine and Hygiene.

Next generation mosquito surveillance technique: the near infra-red spectroscopy

2017

Conference Publication

Investigating the activity of the macrocyclic lactones ivermectin and moxidectin against malaria vectors

Pasay, Cielo, Mills, Paul, Dekkers, Milou, Stewart, Romal, Hugo, Leon, Ong, Oselyne, Wu, Chen, Devine, Greg and McCarthy, James (2017). Investigating the activity of the macrocyclic lactones ivermectin and moxidectin against malaria vectors. 66th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Baltimore, MA United States, 5-9 November 2017. McLean, VA, United States: American Society of Tropical Medicine and Hygiene.

Investigating the activity of the macrocyclic lactones ivermectin and moxidectin against malaria vectors

2016

Journal Article

Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission

Griffin, Paul, Pasay, Cielo, Elliott, Suzanne, Sekuloski, Silvana, Sikulu, Maggy, Hugo, Leon, Khoury, David, Cromer, Deborah, Davenport, Miles, Sattabongkot, Jetsumon, Ivinson, Karen, Ockenhouse, Christian and McCarthy, James (2016). Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission. PLoS Neglected Tropical Diseases, 10 (12) e0005139, e0005139. doi: 10.1371/journal.pntd.0005139

Safety and reproducibility of a clinical trial system using induced blood stage Plasmodium vivax infection and its potential as a model to evaluate malaria transmission

2016

Journal Article

Chikungunya virus transmission between Aedes albopictus and laboratory mice

Hugo, Leon E., Prow, Natalie A., Tang, Bing, Devine, Greg and Suhrbier, Andreas (2016). Chikungunya virus transmission between Aedes albopictus and laboratory mice. Parasites and Vectors, 9 (1) 555. doi: 10.1186/s13071-016-1838-1

Chikungunya virus transmission between Aedes albopictus and laboratory mice

2016

Journal Article

Near-infrared spectroscopy, a rapid method for predicting the age of male and female wild-type and Wolbachia infected Aedes aegypti

Sikulu-Lord, Maggy T., Milali, Masabho P., Henry, Michael, Wirtz, Robert A., Hugo, Leon E., Dowell, Floyd E. and Devine, Gregor J. (2016). Near-infrared spectroscopy, a rapid method for predicting the age of male and female wild-type and Wolbachia infected Aedes aegypti. PLoS Neglected Tropical Diseases, 10 (10) e0005040, e0005040.1-e0005040.11. doi: 10.1371/journal.pntd.0005040

Near-infrared spectroscopy, a rapid method for predicting the age of male and female wild-type and Wolbachia infected Aedes aegypti

2016

Journal Article

Heat sensitivity of wMel Wolbachia during Aedes aegypti development

Ulrich, Jill N., Beier, John C., Devine, Gregor J. and Hugo, Leon E. (2016). Heat sensitivity of wMel Wolbachia during Aedes aegypti development. PLoS Neglected Tropical Diseases, 10 (7) e0004873, e0004873. doi: 10.1371/journal.pntd.0004873

Heat sensitivity of wMel Wolbachia during Aedes aegypti development

2016

Journal Article

Effects of Larval Nutrition on Wolbachia-Based Dengue Virus Interference in Aedes aegypti (Diptera: Culicidae)

Kho, Elise A., Hugo, Leon E., Lu, Guangjin, Smith, David D. and Kay, Brian H. (2016). Effects of Larval Nutrition on Wolbachia-Based Dengue Virus Interference in Aedes aegypti (Diptera: Culicidae). Journal of Medical Entomology, 53 (4), 894-901. doi: 10.1093/jme/tjw029

Effects of Larval Nutrition on Wolbachia-Based Dengue Virus Interference in Aedes aegypti (Diptera: Culicidae)

2016

Journal Article

Rapid and non-destructive detection and identification of two strains of Wolbachia in Aedes aegypti by near-infrared spectroscopy

Sikulu-Lord, Maggy T., Maia, Marta F., Milali, Masabho P., Henry, Michael, Mkandawile, Gustav, Kho, Elise A., Wirtz, Robert A., Hugo, Leon E., Dowell, Floyd E. and Devine, Gregor J. (2016). Rapid and non-destructive detection and identification of two strains of Wolbachia in Aedes aegypti by near-infrared spectroscopy. PLoS Neglected Tropical Diseases, 10 (6) e0004759, e0004759. doi: 10.1371/journal.pntd.0004759

Rapid and non-destructive detection and identification of two strains of Wolbachia in Aedes aegypti by near-infrared spectroscopy

2015

Journal Article

Mass spectrometry identification of age-associated proteins from the malaria mosquitoes Anopheles gambiae s.s. and Anopheles stephensi

Sikulu, Maggy T., Monkman, James, Dave, Keyur A., Hastie, Marcus L., Dale, Patricia E., Kitching, Roger L., Killeen, Gerry F., Kay, Brian H., Gorman, Jeffry J. and Hugo, Leon E. (2015). Mass spectrometry identification of age-associated proteins from the malaria mosquitoes Anopheles gambiae s.s. and Anopheles stephensi. Data in Brief, 4, 461-467. doi: 10.1016/j.dib.2015.07.007

Mass spectrometry identification of age-associated proteins from the malaria mosquitoes Anopheles gambiae s.s. and Anopheles stephensi

2015

Journal Article

Proteomic changes occurring in the malaria mosquitoes Anopheles gambiae and Anopheles stephensi during aging

Sikulu, Maggy T., Monkman, James, Dave, Keyur A., Hastie, Marcus L., Dale, Patricia E., Kitching, Roger L., Killeen, Gerry F., Kay, Brian H., Gorman, Jeffery J. and Hugo, Leon E. (2015). Proteomic changes occurring in the malaria mosquitoes Anopheles gambiae and Anopheles stephensi during aging. Journal of Proteomics, 126, 234-244. doi: 10.1016/j.jprot.2015.06.008

Proteomic changes occurring in the malaria mosquitoes Anopheles gambiae and Anopheles stephensi during aging

2014

Journal Article

Using a near-infrared spectrometer to estimate the age of Anopheles mosquitoes exposed to pyrethroids

Sikulu, Maggy T., Majambere, Silas, Khatib, Bakar O., Ali, Abdullah S., Hugo, Leon E. and Dowell, Floyd E. (2014). Using a near-infrared spectrometer to estimate the age of Anopheles mosquitoes exposed to pyrethroids. PLoS One, 9 (3) e90657, e90657.1-e90657.6. doi: 10.1371/journal.pone.0090657

Using a near-infrared spectrometer to estimate the age of Anopheles mosquitoes exposed to pyrethroids

2014

Journal Article

Adult Survivorship of the Dengue Mosquito Aedes aegypti Varies Seasonally in Central Vietnam

Hugo, Leon E., Jeffery, Jason A. L., Trewin, Brendan J., Wockner, Leesa F., Nguyen Thi Yen, Nguyen Hoang Le, Le Trung Nghia, Hine, Emma, Ryan, Peter A. and Kay, Brian H. (2014). Adult Survivorship of the Dengue Mosquito Aedes aegypti Varies Seasonally in Central Vietnam. PLoS Neglected Tropical Diseases, 8 (2) e2669, e2669.1-e2669.12. doi: 10.1371/journal.pntd.0002669

Adult Survivorship of the Dengue Mosquito Aedes aegypti Varies Seasonally in Central Vietnam

2013

Journal Article

Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission

Hugo, Leon E., Monkman, James, Dave, Keyur A., Wockner, Leesa F., Birrell, Geoff W., Norris, Emma L., Kienzle, Vivian J., Sikulu, Maggy T., Ryan, Peter A., Gorman, Jeffery J. and Kay, Brian H. (2013). Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission. PLoS One, 8 (3) e58656, e58656.1-e58656.10. doi: 10.1371/journal.pone.0058656

Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission

2011

Journal Article

Evaluating RNAlater ® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species

Sikulu, Maggy, Dowell, Kayla M., Hugo, Leon E., Wirtz, Robert A., Michel, Kristin, Peiris, Kamaranga H. S., Moore, Sarah, Killeen, Gerry F. and Dowell, Floyd E. (2011). Evaluating RNAlater ® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species. Malaria Journal, 10 (1) 186. doi: 10.1186/1475-2875-10-186

Evaluating RNAlater ® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species

Supervision

Availability

Dr Leon Hugo is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

For media enquiries about Dr Leon Hugo's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au