Overview
Background
Dr Leon Hugo is a medical entomologist conducting research into the biology of mosquitoes, host-parasite interactions and the development of novel control strategies against arthropod-borne viruses (arboviruses). Dr Hugo is an Honorary Associate Professor through the School of Biomedical Sciences and is also the Academic Lead of the Mosquito Control Laboratory at QIMR Berghofer medical research institute, Brisbane. Dr Hugo has developed and applied experimental mosquito models of arbovirus infection for over 15 years to establish the risk of arbovirus transmission in Australia and new biological controls. Dr Hugo works with physical containment/biosecurity level (PC/BSL) 2 and 3 arboviruses, including dengue, Zika, Japanese encephalitis and chikungunya viruses and performs fundamental research on Wolbachia bacteria and Insect-specific virus (ISV) microbial control agents. Dr Hugo has published 60+ research articles with over 160 collaborators, from academic, medical, government and corporate sectors, across 18 countries. Topic areas his publications have had greatest impact were Japanese Encephalitis and Socioeconomic Impact, Wolbachia’s Role in Mosquito Population Replacement and Insecticide Resistance Mechanisms in Aedes aegypti.
Dr Hugo’s team maintains a living library of native and exotic mosquito species and conducts infection and transmission studies in state-of-the-art PC2 and PC3 insectaries. Research themes including mosquito vector competence, climate change impacts on mosquito-borne disease transmission risk, mosquito and arbovirus surveillance and genomics and novel control strategies, including biological control and the use of endectocides.
Availability
- Dr Leon Hugo is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Research impacts
Seven of Dr Hugo's publications have attracted over 40 citations in policy documents across 8+ countries from agencies including the WHO, State of Hawaii and the OECD.
Works
Search Professor Leon Hugo’s works on UQ eSpace
2010
Journal Article
Investigation of environmental influences on a transcriptional assay for the prediction of age of Aedes aegypti (Diptera: Culicidae) mosquitoes
Hugo, LE, Kay, BH, O'Neill, SL and Ryan, PA (2010). Investigation of environmental influences on a transcriptional assay for the prediction of age of Aedes aegypti (Diptera: Culicidae) mosquitoes. Journal of Medical Entomology, 47 (6), 1044-1052. doi: 10.1603/ME10030
2010
Journal Article
Field validation of a transcriptional assay for the prediction of age of uncaged Aedes aegypti mosquitoes in northern Australia
Hugo, Leon E., Cook, Peter E., Johnson, Petrina H., Rapley, Luke P., Kay, Brian H., Ryan, Peter A., Ritchie, Scott A. and O'Neill, Scott L. (2010). Field validation of a transcriptional assay for the prediction of age of uncaged Aedes aegypti mosquitoes in northern Australia. PLoS Neglected Tropical Diseases, 4 (2) e608, e608-1-e608-9. doi: 10.1371/journal.pntd.0000608
2010
Journal Article
Near-infrared spectroscopy as a complementary age grading and species identification tool for African malaria vectors
Sikulu, Maggy, Killeen, Gerry F., Hugo, Leon E., Ryan, Peter A., Dowell, Kayla M., Wirtz, Robert A., Moore, Sarah J. and Dowell, Floyd E. (2010). Near-infrared spectroscopy as a complementary age grading and species identification tool for African malaria vectors. Parasites and Vectors, 3 (1) 49. doi: 10.1186/1756-3305-3-49
2009
Journal Article
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
Moreira, LA, Iturbe-Ormaetxe, I, Jeffery, JA, Lu, GJ, Pyke, AT, Hedges, LM, Rocha, BC, Hall-Mendelin, S, Day, A, Riegler, M, Hugo, LE, Johnson, KN, Kay, BH, McGraw, EA, van den Hurk, AF, Ryan, PA and O'Neill, SL (2009). A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium. Cell, 139 (7), 1268-1278. doi: 10.1016/j.cell.2009.11.042
2008
Journal Article
Evaluations of Mosquito Age Grading Techniques Based on Morphological Changes
Hugo, R. L., Quick-Mile, S., Kay, B.H. and Ryan, P.A. (2008). Evaluations of Mosquito Age Grading Techniques Based on Morphological Changes. Journal of Medical Entomology, 45 (3), 353-369. doi: 10.1603/0022-2585(2008)45[353:EOMAGT]2.0.CO;2
2007
Journal Article
Predicting the age of mosquitoes using transcriptional profiles
Cook, P. E., Hugo, L. E., Iturbe-Ormaetxe, I., Williams, C. R., Chenoweth, S. F., Ritchie, S. A., Ryan, P. A., Kay, B. H., Blows, M. W. and O'Neill, S. L. (2007). Predicting the age of mosquitoes using transcriptional profiles. Nature Protocols, 2 (11), 2796-2806. doi: 10.1038/nprot.2007.396
2006
Journal Article
The use of transcriptional profiles to predict adult mosquito age under field conditions
Cook, P. E., Hugo, L. E., Iturbe-Ormaetxe, I., Williams, C. R., Chenoweth, S. F., Ritchie, S. A., Ryan, P. A., Kay, B. H., Blows, M. W. and O'Neill, S. L. (2006). The use of transcriptional profiles to predict adult mosquito age under field conditions. Proceedings of the National Academy of Sciences of the United States of America, 103 (48), 18060-18065. doi: 10.1073/pnas.0604875103
2006
Journal Article
Investigation of cuticular hydrocarbons for determining the age and survivorship of Australasian mosquitoes
Hugo, Leon E., Kay, Brian H., Eaglesham, Geoff K., Holling, Neil and Ryan, Peter A. (2006). Investigation of cuticular hydrocarbons for determining the age and survivorship of Australasian mosquitoes. American Journal of Tropical Medicine and Hygiene, 74 (3), 462-474. doi: 10.4269/ajtmh.2006.74.462
2003
Journal Article
Autogeny in Ochlerotatus vigilax (Diptera : Culicidae) from southeast Queensland, Australia
Hugo, L. E., Kay, B. H. and Ryan, P. A. (2003). Autogeny in Ochlerotatus vigilax (Diptera : Culicidae) from southeast Queensland, Australia. Journal of Medical Entomology, 40 (6), 897-902. doi: 10.1603/0022-2585-40.6.897
Supervision
Availability
- Dr Leon Hugo is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Insect-specific viruses as tools for the downregulation of mosquito vector competence for arboviruses
Principal Advisor
Other advisors: Associate Professor Jody Peters
-
Doctor Philosophy
Investigation of factors affecting the maternal transmission of Insect-specific viruses by mosquitoes
Principal Advisor
Other advisors: Associate Professor Jody Peters
-
Doctor Philosophy
Exploring the development of a malaria refractory Anopheles farauti
Associate Advisor
Other advisors: Professor Sassan Asgari, Professor Nigel Beebe
-
Doctor Philosophy
Engineering chimeric viruses as protective and safe vaccines against mosquito-borne viral disease
Associate Advisor
Other advisors: Professor Alexander Khromykh, Dr Andrii Slonchak, Associate Professor Jody Peters
Completed supervision
-
2023
Doctor Philosophy
New tools for managing Aedes-borne diseases in Bangladesh
Associate Advisor
Other advisors: Professor Nigel Beebe
-
2021
Doctor Philosophy
The biological costs and benefits associated with a pyrethroid-resistant genotype of Aedes aegypti
Associate Advisor
Other advisors: Professor Nigel Beebe
-
2020
Doctor Philosophy
Interaction between flaviviruses and the vector Aedes aegypti, an overview into replication and microRNAs
Associate Advisor
Other advisors: Professor Nigel Beebe, Professor Sassan Asgari
-
2020
Doctor Philosophy
Characterization of Wolbachia infections from native Australian mosquitoes
Associate Advisor
Other advisors: Professor Sassan Asgari
Media
Enquiries
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