Dr Robert Reid
Dr

Robert Reid

Email: 

Background

I am an Organic Chemist and research the design and preparation of new medicines for diseases including arthritis and cancer

Dr. Robert C. Reid was awarded B.Sc. Hons 1 (1986) and Ph.D. (1990) degrees from the University of Sydney, Department of Organic Chemistry. He studied the stereospecific total synthesis of complex natural products with Professor Max J. Crossley and then undertook postdoctoral studies with Professor Sir Jack E. Baldwin FRS at the Dyson Perrins Laboratory, Oxford University UK (1990-93) studying the biosynthesis of penicillins. He is a Senior Research Fellow at the Institute for Molecular Bioscience (formerly known as the Centre for Drug Design and Development) at the University of Queensland with Professor David Fairlie. Research interests include Organic Synthesis, medicinal chemistry, drug design and development, nonpeptidic GPCR antagonists, natural products, protease inhibitors, other enzyme inhibitors, and peptidomimetics.

Availability

Dr Robert Reid is:
Available for supervision
Media expert

Fields of research

Biomedical and Clinical Sciences Chemical Sciences Medicinal and biomolecular chemistry Organic chemistry Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor (Honours) of Science (Advanced), University of Sydney
  • Doctor of Philosophy of Organic Chemistry, University of Sydney

Search Professor Robert Reid’s works on UQ eSpace

103 works between 1994 and 2025
All (103) Journal Article (85) Other Outputs (5) Conference Publication (11) Book Chapter (2)

61 - 80 of 103 works

2009

Journal Article

The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis

Cantley, M. D., Bartold, P. M., Marino, V, Reid, R. C., Fairlie, D. P., Wyszynski, R. N., Zilm, P. S. and Haynes, D. R. (2009). The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. Journal of Periodontal Research, 44 (3), 317-322. doi: 10.1111/j.1600-0765.2008.01132.x

The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis

2008

Journal Article

Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism

Tyndall, Joel D. A., Pattenden, Leonard K., Reid, Robert C., Hu, Shu-Hong, Alewood, Dianne, Alewood, Paul F., Walsh, Terry, Fairlie, David P. and Martin, Jennifer L. (2008). Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism. Biochemistry, 47 (12), 3736-3744. doi: 10.1021/bi7023157

Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism

2008

Journal Article

Clean Or dirty - Just how selective do drugs need to be?

Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2008). Clean Or dirty - Just how selective do drugs need to be?. Australian Journal of Chemistry, 61 (9), 654-660. doi: 10.1071/CH08186

Clean Or dirty - Just how selective do drugs need to be?

2008

Book Chapter

Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids

Reid, Robert, C. and Fairlie, David P. (2008). Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids. High-throughput lead optimisation in drug discovery. (pp. 177-194) edited by Tushar Kshirsagar. Boca Raton, USA: CRC Press. doi: 10.1201/9781420006964.ch7

Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids

2007

Other Outputs

New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis

Clark, C. I., Fairlie, D. P., Hansford, K., McGeary, R. P., Reid, R. C. and Stoermer, M. J. (2007). New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis.

New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis

2007

Other Outputs

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P., Fairlie, David P. and Schafer, Karl (2007). Compounds and inhibitors of phospholipases. US7253194.

Compounds and inhibitors of phospholipases

2007

Journal Article

The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding

Scola, A. M., Higginbottom, A., Partridge, L, J., Reid, R. C., Woodruff, T., Taylor, S. M., Fairlie, D. P. and Monk, P. N. (2007). The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. Journal of Biological Chemistry, 282 (6), 3664-3671. doi: 10.1074/jbc.M609178200

The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding

2007

Journal Article

Nonpeptidic ligands for peptide-activated G protein-coupled receptors

Blakeney, J. S, Reid, R. C, Le, G. T and Fairlie, D. P (2007). Nonpeptidic ligands for peptide-activated G protein-coupled receptors. Chemical Reviews, 107 (7), 2960-3041. doi: 10.1021/cr050984g

Nonpeptidic ligands for peptide-activated G protein-coupled receptors

2006

Conference Publication

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators. WASHINGTON: AMER CHEMICAL SOC.

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

2006

Journal Article

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

Gregory, Laura S., Kelly, Wendy L., Reid, Robert C., Fairlie, David P. and Forwood, Mark R. (2006). Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. Bone, 39 (1), 134-142. doi: 10.1016/j.bone.2005.12.017

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

2006

Journal Article

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006). Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 (11), 7000-7007. doi: 10.4049/jimmunol.176.11.7000

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

2006

Journal Article

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

2006

Conference Publication

Alpha helix induction in HIV REV34-50 by N-terminal nucleators

Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). Alpha helix induction in HIV REV34-50 by N-terminal nucleators. 232nd ACS National Meeting, San Francisco, CA, U.S.A., 10-14 September, 2006. American Chemical Society. doi: 10.1021/cen-v084n034.p055

Alpha helix induction in HIV REV34-50 by N-terminal nucleators

2005

Journal Article

Inhibitors of Secretory Phospholipase A2 Group IIA

Reid, Robert C. (2005). Inhibitors of Secretory Phospholipase A2 Group IIA. Current medicinal chemistry, 12 (25), 3011-3026. doi: 10.2174/092986705774462860

Inhibitors of Secretory Phospholipase A2 Group IIA

2005

Journal Article

A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis

Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005). A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 (5), 883-892. doi: 10.1016/j.intimp.2005.01.003

A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/S0168-8278(04)00066-2

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and M. Colombo (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/j.jhep.2004.02.017

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Other Outputs

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P., Fairlie, David P. and Schafer, Karl (2004). Compounds and inhibitors of phospholipases. US2004033995.

Compounds and inhibitors of phospholipases

2004

Journal Article

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

Proctor, Lavinia M., Arumugam, Thiruma V., Shiels, Ian, Reid, Robert C., Fairlie, David P. and Taylor, Stephen M . (2004). Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury. British Journal of Pharmacology, 142 (4), 756-764. doi: 10.1038/sj.bjp.0705819

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

2004

Journal Article

Countering cooperative effects in protease inhibitors using constrained b-strand-mimicking templates in focused combinatorial libraries

Reid, Robert C., Pattenden, Lenard K., Tyndall, Joel D. A., Martin, Jennifer L., Walsh, Terry and Fairlie, David P. (2004). Countering cooperative effects in protease inhibitors using constrained b-strand-mimicking templates in focused combinatorial libraries. Journal of Medicinal Chemistry, 47 (7), 1641-1651. doi: 10.1021/jm030337m

Countering cooperative effects in protease inhibitors using constrained b-strand-mimicking templates in focused combinatorial libraries

Past funding

  • 2014
    Continuous-Flow Hydrogenation Reactor (H-Cube Pro)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Peptide Drug Synthesis and Purification Unit
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Combinatorial chemistry (high throughput synthesizer and purification system)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Inhibitors of Secretory Phospholipases in Diet Induced Obese Rats
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    Protease Activated Receptor 2 : A New Drug Target For Inflammatory Diseases and Cancer
    NHMRC Project Grant
    Open grant
  • 2008 - 2010
    Molecular attributes and physiological significance of beta1L-adrenoceptors
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    DsbA inhibitors as potential antimicrobials
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    Targeting A Complement Receptor That Regulates Inflammatory Disease
    NHMRC Project Grant
    Open grant
  • 2000
    Development of inhibit
    UQ External Support Enabling Grant
    Open grant

Availability

Dr Robert Reid is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Dr Robert Reid directly for media enquiries about:

  • Chemical Analysis
  • HPLC
  • LCMS
  • Medicinal Chemistry
  • NMR
  • Organic Chemistry
  • Organic Synthesis
  • Spectroscopy

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au