
Overview
Background
Professor David McIntyre trained in Endocrinology in Australia and Belgium. He works clinically as Director of Obstetric Medicine at Mater Health Services and is an Emeritus Professor in the Faculty of Medicine (Mater Research). David has published over 250 papers (>25000 citations), primarily in the field of medical complications of pregnancy, with a particular focus on diabetes and obesity. Recent research has examined the effects of diabetes, obesity and hypertension during pregnancy on the health of Mothers and Babies, during pregnancy and with long term follow up. David is a Past Chair of the Australasian Diabetes in Pregnancy Society and the International Association of Diabetes in Pregnancy Study Groups (IADPSG). In 2016, David became the first Australian trained clinician to receive the Norbert Freinkel Award for contributions to diabetes in pregnancy from the American Diabetes Association. In 2019 he was awarded the Jørgen Pedersen Lecture for diabetes in pregnancy by DPSG Europe and the Stream Lead Award Lecture for “Diabetes and Women” by the International Diabetes Federation.
Availability
- Emeritus Professor David McIntyre is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctoral Diploma of Medicine, The University of Queensland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research interests
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DIabetes in pregnancy
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Medical complications of pregnancy
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Obesity in pregnancy
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Intensive insulin therapy in Type 1 diabetes
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Life course epidemiology of cardiometabolic disease
Research impacts
Direct impact on clinical practice:
- Testing for gestational diabetes mellitus (GDM). Professor McIntyre has been centrally involved in the development and dissemination of the IADPSG recommendations for diagnosis of GDM. This has included membership of the consensus conference, which developed the IADPSG recommendations, and of the writing group, which finalized the proposed criteria. On a national level, he was involved in representations to the college of Obstetrics and Gynecology, ADIPS and the Australian Diabetes Society (ADS) as well as within Queensland) and locally at the Mater Mothers Hospital. He chaired the GDM workgroup for the Statewide Clinical Diabetes Network and was lead author on local GDM guidelines. Internationally, he has been closely involved in similar processes as Chair of IADPSG and a member of the FIGO Pregnancy and Non Communicable Disease (NCD) committee.
- Intensive diabetes management. Since 2004, he has been a founding member of the OzDAFNE collaboration, which introduced the Dose Adjustment for Normal Eating (DAFNE) system of education in intensive insulin therapy for Type 1 diabetes patients into clinical practice in Australia. This has become the mainstay of such treatment in Queensland and DAFNE courses are now offered in over 20 centres across Australia and New Zealand.
Clinical Practice Guidelines:
Professor McIntyre participated in the development of clinical practice guidelines for Obesity in pregnancy via the Statewide Maternity and Neonatal Network and served as Co-lead of the group which developed a guideline for GDM diagnosis and treatment published in 2015.
Investigator-initiated Clinical Trials:
- He has been involved in the MiG trial of metformin in the management of gestational diabetes and I have started the first Australian site for the “MiTY” (Metformin in Type 2 diabetes) trial to further examine the use of this medication in pregnancy.
- He was Chief Investigator B and lead at Mater Health Services for the “SPRING” (Supplementation with Probiotics in Gestation) trial recently reported its negative findings regarding the use of probiotics in GDM prevention.
- He has initiated two RCTs dealing with lifestyle strategies in the prevention of progression to Type 2 diabetes following GDM.
- He was CI on a further RCT “TRIM” (Trial of Weight Reduction in New Mums) dealing with optimal dietary follow up to reduce post-partum weight retention in obese pregnant women.
Public Health: Throughhis ole in the National Diabetes in Pregnancy Advisory Committee, he hascontributed to definition of priorities for the care of women with diabetes before, during and after pregnancy. Hiscontributions to GDM care also relate to Public Health as GDM is the commonest identifiable antecedent to overt Type 2 diabetes in parous women.
Works
Search Professor David McIntyre’s works on UQ eSpace
2006
Journal Article
Structured Patient Education such as DAFNE and Insulin Pump Therapy in Type 1 Diabetes - Compatible or Competitors?
McIntyre, H. and Knight, B. (2006). Structured Patient Education such as DAFNE and Insulin Pump Therapy in Type 1 Diabetes - Compatible or Competitors?. Infusystems Asia, 1 (4), 25-28.
2005
Journal Article
How to Treat – Gestational diabetes mellitus
Mann, Linda and McIntyre, David (2005). How to Treat – Gestational diabetes mellitus. Australian Doctor, 25-32.
2005
Journal Article
The Australasian Diabetes in Pregnancy Society consensus guidelines for the management of type 1 and type 2 diabetes in relation to pregnancy
McElduff, Aidan, Cheung, N. Wah, McIntyre, H. David, Lagstrom, Janet A., Oats, Jeremy J. N., Ross, Glynis P., Simmons, David, Walters, Barry N. J. and Wein, Peter (2005). The Australasian Diabetes in Pregnancy Society consensus guidelines for the management of type 1 and type 2 diabetes in relation to pregnancy. Medical Journal of Australia, 183 (7), 373-377.
2005
Journal Article
Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]
The FIELD Study Investigators and McIntyre, H. D. (2005). Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]. Cardiovascular Diabetology, 4 (Articl No 13), 1-9. doi: 10.1186/1475-2840-4-13
2005
Journal Article
ADVANCE - Action in Diabetes and Vascular Disease : patient recruitment and characteristics of the study population at baseline
Advance Collaborative Group, McIntyre, Harold D. and Morton, Adam (2005). ADVANCE - Action in Diabetes and Vascular Disease : patient recruitment and characteristics of the study population at baseline. Diabetic Medicine, 22 (7), 882-888. doi: 10.1111/j.1464-5491.2005.01596.x
2005
Journal Article
Consensus statement on diabetes control in preparation for pregnancy
Walters, Barry N. J., Senaratne, Sivanthi, McIntyre, H. David and Flack, Jeff R. (2005). Consensus statement on diabetes control in preparation for pregnancy. Medical Journal of Australia, 182 (3), 141-142.
2005
Journal Article
Pregnancy outcomes in women of very advanced maternal age
Callaway, Leonie K., Lust, Karin and McIntyre, H. David (2005). Pregnancy outcomes in women of very advanced maternal age. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45 (1), 12-16. doi: 10.1111/j.1479-828X.2005.00333.x
2005
Journal Article
Gestational diabetes mellitus: From consensus to action on screening and treatment
McIntyre, H. David, Cheung, N. Wah, Oats, Jeremy J. N. and Simmons, David (2005). Gestational diabetes mellitus: From consensus to action on screening and treatment. Medical Journal of Australia, 183 (6), 288-289.
2005
Journal Article
Adipose tissue from pregnant women with and without gestational diabetes mellitus: Insulin-sensitive but resistant to hyperosmolarity
Russell, Anthony W., McIntyre, H. David, Whitehead, Jon P. and Prins, Johannes B. (2005). Adipose tissue from pregnant women with and without gestational diabetes mellitus: Insulin-sensitive but resistant to hyperosmolarity. American Journal of Obstetrics and Gynecology, 193 (6), 2017-2023. doi: 10.1016/j.ajog.2005.04.058
2005
Journal Article
Australian carbohydrate intolerance study in pregnant women: implications for the management of gestational diabetes
Cheung, N. W., Oats, J. J. N. and McIntyre, H. D. (2005). Australian carbohydrate intolerance study in pregnant women: implications for the management of gestational diabetes. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45 (6), 484-485. doi: 10.1111/j.1479-828X.2005.00481.x
2005
Journal Article
Effectiveness and side effects of thiazolidinediones for type 2 diabetes
Morton, Adam P. and McIntyre, Harold D. (2005). Effectiveness and side effects of thiazolidinediones for type 2 diabetes. Medical Journal of Australia, 182 (9), 492-493.
2004
Journal Article
Metformin therapy and diabetes in pregnancy - Reply
Simmons, D., Walters, B. N. J., Rowan, J. A. and McIntyre, H. D. (2004). Metformin therapy and diabetes in pregnancy - Reply. Medical Journal of Australia, 181 (3), 175-175.
2004
Journal Article
Metformin crosses the placenta: A modulator for fetal insulin resistance?
Charles, B.G., Davoren, P. M., Hague, W. M., McIntyre, D., Norris, R. and Xiaonian, X. (2004). Metformin crosses the placenta: A modulator for fetal insulin resistance?. British Medical Journal, 327 (7420), 880-881.
2004
Journal Article
Revision of guidelines for the management of gestational diabetes mellitus [Letter to the Editor]
Oats, J. J. N. and McIntyre, H. D. (2004). Revision of guidelines for the management of gestational diabetes mellitus [Letter to the Editor]. Medical Journal of Australia, 181 (6), 342-342.
2004
Conference Publication
A new HPLC method for analysis of metformin in cord plasma - application to placental transfer studies
Norris, R., Xiaonian, X., Hague, W. M., McIntyre, H.D. and Charles, B. G. (2004). A new HPLC method for analysis of metformin in cord plasma - application to placental transfer studies. Array, Brisbane, 1-6 Aug 2004. Australia: Blackwell Publishing.
2004
Journal Article
Consensus Statement on Diabetes Control in Preparation for Pregnancy
McIntyre, H. David and Flack, Jeff R. (2004). Consensus Statement on Diabetes Control in Preparation for Pregnancy. Medical Journal of Australia, 181 (6), 326-326.
2004
Journal Article
Metformin therapy and diabetes in pregnancy
Simmons, D., Walters, B. N. J., Rowan, J. A. and McIntyre, H. D. (2004). Metformin therapy and diabetes in pregnancy. Medical Journal of Australia, 180 (9), 462-464.
2003
Journal Article
Cardiac function in fetuses of poorly-controlled pre-gestational diabetic pregnancies - a pilot study
Wong, S.F., Chan, F. Y., Cincotta, R., McIntyre, H. D. and Oats, J. (2003). Cardiac function in fetuses of poorly-controlled pre-gestational diabetic pregnancies - a pilot study. Gynecologic and Obstetric Investigation, 56 (2), 113-116. doi: 10.1159/000073191
2003
Conference Publication
Glucose uptake and insulin-signaling in human adipose tissue in pregnancy
Russell, A. W., Whitehead, J. P., McIntyre, H. D. and Prins, J. B. (2003). Glucose uptake and insulin-signaling in human adipose tissue in pregnancy. IDF Congress Paris 2003, Paris, France, 24–29 August, 2003. Berlin: Springer-Verlag. doi: 10.1007/s00125-003-1190-9
2003
Conference Publication
Metformin crosses the placenta
Hague, W.M., Davoren, P.M., McIntyre, D., Norris, R., Xiaonian, X. and Charles, B. G. (2003). Metformin crosses the placenta. Medicine and Pregnancy 2003, Fremantle, WA, 21-25 Oct 2003. WA: ADIPS.
Funding
Current funding
Supervision
Availability
- Emeritus Professor David McIntyre is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Pregnancy after bariatric surgery
Associate Advisor
Other advisors: Associate Professor Marloes Nitert Dekker
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Doctor Philosophy
Multidisciplinary efforts to eliminate sexually transmissible infections in regional and remote Australia
Associate Advisor
Other advisors: Professor James Ward, Professor Abdullah Mamun
-
Doctor Philosophy
Implementing a life course approach in antenatal and postnatal care settings for prevention and reduction of non-communicable disease risks in Nepal (IpreventNCD)
Associate Advisor
Other advisors: Professor Abdullah Mamun
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Doctor Philosophy
Pregnancy after bariatric surgery
Associate Advisor
Other advisors: Associate Professor Marloes Nitert Dekker
Completed supervision
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2017
Doctor Philosophy
Flexible multiple injection therapy education for adults with Type 1 diabetes: experience and innovation in the Australian setting.
Principal Advisor
Other advisors: Associate Professor Ingrid Hickman
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2007
Doctor Philosophy
OBESITY AND HYPERTENSIVE DISORDERS OF PREGNANCY: ASSOCIATIONS WITH IMMEDIATE PREGNANCY OUTCOMES AND LONG TERM MATERNAL HEALTH
Principal Advisor
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2024
Doctor Medical Leadership
Gestational Diabetes Mellitus: Care Re-imagined
Associate Advisor
Other advisors: Dr Shelley Wilkinson
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2024
Master Philosophy
The role of Australian General Practitioners in working with patients with Gestational Diabetes Mellitus
Associate Advisor
Other advisors: Dr Ben Mitchell, Professor Leonie Callaway
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2023
Doctor Philosophy
Life Course Predictors of Gestational Diabetes Mellitus
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2015
Doctor Philosophy
A Mixed methods Study of Interventions and Experiences to Prevent Type 2 Diabetes Mellitus following Gestational Diabetes
Joint Principal Advisor
Other advisors: Dr Fiona Bogossian, Dr Shelley Wilkinson
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2023
Doctor Philosophy
An assessment of an adaptive, personalised, and co-designed educational digital health intervention: a novel approach to empowerment and support of women with gestational diabetes
Associate Advisor
Other advisors: Dr Nigel Armfield, Dr Sisira Edirippulige
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2023
Doctor Philosophy
Resemblance of parent-offspring dietary patterns and the development of offspring cardiometabolic risks: A life course perspective
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2022
Doctor Philosophy
Placental-derived extracellular vesicles as liquid biopsies to monitor complications of pregnancy
Associate Advisor
Other advisors: Professor Yusuke Yamauchi, Professor Carlos Salomon Gallo
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2021
Doctor Philosophy
Identification of therapeutic targets to regulate insulin sensitivity: Potential role of placental exosomes
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo
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2019
Doctor Philosophy
Early life predictors of young adulthood renal function
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2019
Doctor Philosophy
Insulin requirements in pregnancy and breastfeeding in type 1 diabetes
Associate Advisor
Other advisors: Professor Leonie Callaway
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2017
Doctor Philosophy
The association between parental overweight and obesity before pregnancy and the development of offspring overweight and obesity in childhood, adolescence and young adulthood
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2015
Doctor Philosophy
Communication between Hospital Clinicians, General Practitioners and Women: Postpartum Follow-up of Mothers with Gestational Diabetes Mellitus
Associate Advisor
Other advisors: Dr Fiona Bogossian, Professor Leonie Callaway
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2014
Doctor Philosophy
Maternal lipids and placental lipases in complicated pregnancy.
Associate Advisor
Other advisors: Professor Leonie Callaway, Associate Professor Marloes Nitert Dekker
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2013
Doctor Philosophy
Performance of Birth Weight Models
Associate Advisor
Other advisors: Professor Abdullah Mamun
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2012
Doctor Philosophy
The role of 11ß-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome
Associate Advisor
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2004
Doctor Philosophy
CHANGE IN INSULIN SENSITIVITY AND SIGNALLING IN ADIPOSE TISSUE AND SKELETAL MUSCLE IN PREGNANT WOMEN IN GESTATIONAL DIABETES: THE INFLUENCE OF GESTATIONAL HORMONES, TNF-ALPHA AND THIAZOLIDINEDIONES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor David McIntyre directly for media enquiries about:
- diabetes
- gestational diabetes
- obesity
- pregnancy
- type 1 diabetes
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