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2007

Journal Article

The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor

Meadows, Nicholas A., Sharma, Sudarshana M., Faulkner, Geoffrey J., Ostrowski, Michael C., Hume, David A. and Cassady, Alan I. (2007). The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. Journal of Biological Chemistry, 282 (3), 1891-1904. doi: 10.1074/jbc.M608572200

The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor

2007

Conference Publication

Colony Stimulating Factor Reverses Established Renal Injury in An Acute Ischemic Mouse Model

Ricardo, S. D., Alikhan, M. A., Campanale, N. V., Hume, D. A. and Little, M. H. (2007). Colony Stimulating Factor Reverses Established Renal Injury in An Acute Ischemic Mouse Model. HOBOKEN: WILEY-BLACKWELL.

Colony Stimulating Factor Reverses Established Renal Injury in An Acute Ischemic Mouse Model

2007

Conference Publication

Osteal Macrophages: Novel regulators of Bone Formation

Raggatt, L. J., Chang, M. K., Alexander, K. A., Kuiliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal Macrophages: Novel regulators of Bone Formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, 16th -19th September, 2007. Washington, D.C., United States: American Society for Bone and Mineral Research.

Osteal Macrophages: Novel regulators of Bone Formation

2007

Journal Article

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

Bode, K. A., Schroder, K., Hume, D. A., Ravasi, T., Heeg, K., Sweet, M. J. and Dalpke, A. H. (2007). Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology, 122 (4), 596-606. doi: 10.1111/j.1365-2567.2007.02678.x

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

2007

Journal Article

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter

Rae, Fiona, Woods, Kyra, Sasmono, Tedjo, Campanale, Naomi, Taylor, Darrin, Ovchinnikov, Dmitry A., Grimmond, Sean M., Hume, David A., Ricardo, Sharon D. and Little, Melissa H. (2007). Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Developmental Biology, 308 (1), 232-246. doi: 10.1016/j.ydbio.2007.05.027

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter

2007

Journal Article

Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis

Hinshelwood, Rebecca A., Huschtscha, Lily I., Melki, John, Stirzaker, Clare, Abdipranoto, Andrea, Vissel, Bryce, Ravasi, Timothy, Wells, Christine A., Hume, David A., Reddel, Roger R. and Clark, Susan J. (2007). Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis. Cancer Research, 67 (24), 11517-11527. doi: 10.1158/0008-5472.CAN-07-1284

Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis

2007

Conference Publication

Osteal macrophages: Novel regulators of bone formation

Raggatt, L. J., Alexander, K. A., Kuliwaba, J. S., Fazzalari, N. L., Hume, D. A. and Pettit, A. R. (2007). Osteal macrophages: Novel regulators of bone formation. 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI, United States, 16-19 September 2007.

Osteal macrophages: Novel regulators of bone formation

2007

Conference Publication

Colony Stimulating Factor (Csf)-1 Promotes Nephrogenesis and Postnatal Growth in Newborn Mice

Jones, C. V., Little, M. H., Hume, D. A. and Ricardo, S. D. (2007). Colony Stimulating Factor (Csf)-1 Promotes Nephrogenesis and Postnatal Growth in Newborn Mice. HOBOKEN: WILEY-BLACKWELL.

Colony Stimulating Factor (Csf)-1 Promotes Nephrogenesis and Postnatal Growth in Newborn Mice

2007

Conference Publication

Discussion

Alexander, Warren S., Belz, Gabrielle, Britton, Warwick J., Cook, Matthew, Cyster, Jason, Goodnow, Christopher C., Hume, David, Kaufman, Jim, Mackay, Charles, Stacker, Steven and Turner, Stephen (2007). Discussion. Symposium on Cortical development: genes and genetic abnormalities, London, United Kingdom, 6–8 February 2007. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Discussion

2007

Journal Article

S100A8/S100A9 and their association with cartilage and bone

Zreiqat, H., Howlett, C.R., Gronthos, S., Hume, D. and Geczy, C.L. (2007). S100A8/S100A9 and their association with cartilage and bone. Journal of Molecular Histology, 38 (5), 381-391. doi: 10.1007/s10735-007-9117-2

S100A8/S100A9 and their association with cartilage and bone

2007

Conference Publication

The Jun N-terminal kinases are important for the survival and development of macrophages

Sester, D. P., Hines, S. R., Ravasi, T., Cronau, S. L., Sasmono, T. and Hume, D. A. (2007). The Jun N-terminal kinases are important for the survival and development of macrophages. Annual Congress of the British Society of Immunology, Glasgow, Scotland, 20-23 February 2007. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

The Jun N-terminal kinases are important for the survival and development of macrophages

2007

Conference Publication

The endosteal bone niche contains macrophages that regulate osteoblast function

Pettit, A. R., Chang, M. K., Alexander, K. A., Wu, A. C., Hume, D. A. and Raggatt, L. J. (2007). The endosteal bone niche contains macrophages that regulate osteoblast function. 17th Scientific Meeting of the International Bone & Mineral Society, Montreal, Canada, 24-29 June 2007. New York: Elsevier Science. doi: 10.1016/j.bone.2007.04.166

The endosteal bone niche contains macrophages that regulate osteoblast function

2007

Journal Article

Mammalian RNA polymerase II core promoters: insights from genome-wide studies

Sandelin, A, Carninci, P, Lenhard, B, Ponjavic, J, Hayashizaki, Y and Hume, DA (2007). Mammalian RNA polymerase II core promoters: insights from genome-wide studies. Nature Reviews Genetics, 8 (6), 424-436. doi: 10.1038/nrg2026

Mammalian RNA polymerase II core promoters: insights from genome-wide studies

2007

Conference Publication

General discussion I

Goodnow C.C., Maizels R.M., Hume D., Kaufman J., Schonbach C., Gros P. and Britton W.J. (2007). General discussion I.

General discussion I

2007

Conference Publication

Transcriptional regulatory networks in macrophages

Hume D.A., Wells C.A. and Ravasi T. (2007). Transcriptional regulatory networks in macrophages.

Transcriptional regulatory networks in macrophages

2007

Journal Article

Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1

Sasmono, R. T., Ehrnsperger, A., Cronau, S. L., Ravasi, T., Kandane, R., Hickey, M. J., Cook, A. D., Himes, S. R., Hamilton, J. A. and Hume, D. A. (2007). Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1. Journal of Leukocyte Biology, 82 (1), 111-123. doi: 10.1189/jlb.1206713

Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1

2007

Conference Publication

Discussion

Belz, Gabrielle, Britton, Warwick J., Casanova, Jean-Laurent, Foote, Simon, Goodnow, Christopher C., Gros, Philippe, Hume, David, Maizels, Rick M. and Turner, Stephen (2007). Discussion. Symposium on Cortical development: genes and genetic abnormalities, London, United Kingdom, 6–8 February 2007. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Discussion

2006

Journal Article

CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway

Sester, D. P., Brion, K., Trieu, A., Goodridge, H. S., Roberts, T. L., Dunn, J., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2006). CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. Journal of Immunology, 177 (7), 4473-4480. doi: 10.4049/jimmunol.177.7.4473

CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway

2006

Journal Article

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006). A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 (11), 1921-1923. doi: 10.1096/fj.06-5848fje

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

2006

Journal Article

Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) mice

Yan, Cong, Lian, Xuemei, Li, Yuan, Dai, Ying, White, Amanda, Qin, Yulin, Li, Huimin, Hume, David A. and Du, Hong (2006). Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) mice. American Journal of Pathology, 169 (3), 916-926. doi: 10.2353/ajpath.2006.051327

Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) mice