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2007 Journal Article Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitmentBode, K. A., Schroder, K., Hume, D. A., Ravasi, T., Heeg, K., Sweet, M. J. and Dalpke, A. H. (2007). Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology, 122 (4), 596-606. doi: 10.1111/j.1365-2567.2007.02678.x |
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2007 Journal Article Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporterRae, Fiona, Woods, Kyra, Sasmono, Tedjo, Campanale, Naomi, Taylor, Darrin, Ovchinnikov, Dmitry A., Grimmond, Sean M., Hume, David A., Ricardo, Sharon D. and Little, Melissa H. (2007). Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Developmental Biology, 308 (1), 232-246. doi: 10.1016/j.ydbio.2007.05.027 |
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2007 Journal Article Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesisHinshelwood, Rebecca A., Huschtscha, Lily I., Melki, John, Stirzaker, Clare, Abdipranoto, Andrea, Vissel, Bryce, Ravasi, Timothy, Wells, Christine A., Hume, David A., Reddel, Roger R. and Clark, Susan J. (2007). Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis. Cancer Research, 67 (24), 11517-11527. doi: 10.1158/0008-5472.CAN-07-1284 |
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2007 Conference Publication General discussion IGoodnow C.C., Maizels R.M., Hume D., Kaufman J., Schonbach C., Gros P. and Britton W.J. (2007). General discussion I. |
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2007 Conference Publication Transcriptional regulatory networks in macrophagesHume D.A., Wells C.A. and Ravasi T. (2007). Transcriptional regulatory networks in macrophages. |
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2006 Journal Article CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathwaySester, D. P., Brion, K., Trieu, A., Goodridge, H. S., Roberts, T. L., Dunn, J., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2006). CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. Journal of Immunology, 177 (7), 4473-4480. doi: 10.4049/jimmunol.177.7.4473 |
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2006 Journal Article Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) miceYan, Cong, Lian, Xuemei, Li, Yuan, Dai, Ying, White, Amanda, Qin, Yulin, Li, Huimin, Hume, David A. and Du, Hong (2006). Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal(-/-) mice. American Journal of Pathology, 169 (3), 916-926. doi: 10.2353/ajpath.2006.051327 |
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2006 Journal Article A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populationsIrvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006). A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 (11), 1921-1923. doi: 10.1096/fj.06-5848fje |
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2006 Journal Article Comment on "CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes"Hume, David A. (2006). Comment on "CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes". Journal of Immunology, 177 (4), 2035-2035. doi: 10.4049/jimmunol.177.4.2035 |
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2006 Journal Article Transcriptional network dynamics in macrophage activationNilsson, Roland, Bajic, Vladimir B., Suzuki, Harukazu, di Bernardo, Diego, Bjorkegren, Johan, Katayama, Shintaro, Reid, James F., Sweet, Matthew J., Gariboldi, Manuela, Carninci, Piero, Hayashizaki, Yosihide, Hume, David A., Tegner, Jesper and Ravasi, Timothy (2006). Transcriptional network dynamics in macrophage activation. Genomics, 88 (2), 133-142. doi: 10.1016/j.ygeno.2006.03.022 |
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2006 Journal Article Mice and men: Their promoter propertiesBajic, Vladimir B., Tan, Sin Lam, Christoffels, Alan, Schonbach, Christian, Lilpovich, Leonard, Yang, Liang, Hofmann, Oliver, Kruger, Adele, Hide, Winston, Kai, Chikatoshi, Kawai, Jun, Hume, David A., Carninci, Piero and Hayashizaki, Yoshihide (2006). Mice and men: Their promoter properties. Plos Genetics, 2 (4) e54, 614-626. doi: 10.1371/journal.pgen.0020054 |
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2006 Journal Article Transcript annotation in FANTOM3: Mouse gene catalog based on physical cDNAsMaeda, Norihiro, Kasukawa,Takeya, Frith, Martin, Aturaliya, Rajith N., Forrest, Alistair R. R., Ravasi,Timothy, Teasdale, Rohan D., Wells, Christine A., Hume,David A. and Hayashizaki,Yoshihide (2006). Transcript annotation in FANTOM3: Mouse gene catalog based on physical cDNAs. PLoS Genetics, 2 (4) e62, 498-503. doi: 10.1371/journal.pgen.0020062 |
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2006 Journal Article Alternate transcription of the Toll-like receptor signaling cascadeWells, C. A., Chalk, A. M., Forrest, A., Taylor, D., Waddell, N., Schroder, K., Himes, S. R., Faulkner, G., Lo, S., Kasukawa, T., Kawaji, H., Kai, C., Kawai, J., Katayama, S., Carninci, P., Hayashizaki, Y., Hume, D. A. and Grimmond, S. M. (2006). Alternate transcription of the Toll-like receptor signaling cascade. Genome Biology, 7 (2) R10, R10.1-R10.17. doi: 10.1186/gb-2006-7-2-r10 |
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2006 Journal Article The JNK are important for development and survival of macrophagesHimes, S. Roy, Sester, David P., Ravasi, Timothy, Cronau, Stephen L., Sasmono, Tedjo and Hume, David A. (2006). The JNK are important for development and survival of macrophages. Journal Of Immunology, 176 (4), 2219-2228. doi: 10.4049/jimmunol.176.4.2219 |
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2006 Journal Article Innate immunityHume, David and Hertzog, Paul (2006). Innate immunity. Current Opinion in Immunology, 18 (1), 1-2. doi: 10.1016/j.coi.2005.11.016 |
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2006 Journal Article Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate)Wu, Andy C. K., Grondahl, Lisbeth, Jack, Kevin S., Foo, Michelle X., Trau, Matt, Hume, David A. and Cassady, Alan I. (2006). Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate). Biomaterials, 27 (27), 4715-4725. doi: 10.1016/j.biomaterials.2006.05.010 |
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2006 Journal Article An automatable screen for the rapid identification of proteins amenable to refoldingCowieson, Nathan P., Wensley, Beth, Listwan, Pawel, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2006). An automatable screen for the rapid identification of proteins amenable to refolding. Proteomics, 6 (6), 1750-1757. doi: 10.1002/pmic.200500056 |
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2006 Journal Article Genome-wide analysis of mammalian promoter architecture and evolutionCarninci, Piero, Sandelin, Albin, Lenhard, Boris, Frith, Martin C., Forrest, Alistair R. R., Ravasi, Timothy, Grimmond, Sean M., Wells, Christine A., Hume, David A. and Hayashizaki, Yoshihide (2006). Genome-wide analysis of mammalian promoter architecture and evolution. Nature Genetics, 38 (6), 626-635. doi: 10.1038/ng1789 |
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2006 Journal Article Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular dockingMouradov, D., Craven, A., Forwood, J. K., Flanagan, J. U., Garcia-Castellanos, R., Gomis-Ruth, F. X., Hume, D. A., Martin, J. L., Kobe, B. and Huber, T. (2006). Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking. Protein Engineering Design & Selection, 19 (1), 9-16. doi: 10.1093/protein/gzi070 |
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2006 Journal Article Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 ExpressionInoue, Kenji, Kobayashi, Mika, Yano, Kiichiro, Miura, Mai, Izumi, Akashi, Mataki, Chikage, Doi, Takeshi, Hamakubo, Takao, Reid, Patrick C., Hume, David A., Yoshida, Minoru, Aird, William C., Kodama, Tatsuhiko and Minami, Takashi (2006). Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 Expression. Arteriosclerosis Thrombosis And Vascular Biology, 26 (12), 2652-2659. doi: 10.1161/01.ATV.0000247247.89787.e7 |
