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Dr Jenny Fung
Dr

Jenny Fung

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Overview

Background

Dr Jenny Fung is a senior postdoctoral research fellow and lecturer of pharmacology course at the School of Biomedical Sciences (SBMS), UQ. She is an emerging researcher in the reproductive disease field with experience in molecular biology techniques, genetics, functional genomics, statistical and high-throughput computational skills, ex-vivo and in-vivo models of diseases, as well as industry engagement. In 2013, she was awarded a PhD at UQ and continued post-doctoral research in Professor Grant Montgomery's laboratory at QIMRB and IMB, in the field of genetics and genomics with a focus on functional genomics studies in complex diseases and a special interest in endometriosis. Her research has led to the seminal publication identifying the genetics of gene expression in endometrium and the role of gene regulation underlying endometriosis-related pathogenesis. In 2019, she joined Professor Trent Woodruff’s laboratory at SBMS, UQ to work on immunotherapy development for cancer through funding from Pfizer, where she performed immune cell functional assays and genomics analyses. Dr Fung is in a unique position to perform both the wet and dry lab components of multi-disciplinary research. She is currently co-leading multiple projects, where she is contributing her expertise on genetics and functional genomics on immunology to discover target genes and putative pathways underlying disease progression, with an ultimate goal to develop potential effective drugs for reproductive and brain disorders.

Availability

Dr Jenny Fung is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Jenny Fung’s works on UQ eSpace

48 works between 2010 and 2024

1 - 20 of 48 works

2024

Journal Article

A High-Throughput Method for Quantifying Drosophila Fecundity

Gomez, Andreana, Gonzalez, Sergio, Oke, Ashwini, Luo, Jiayu, Duong, Johnny B., Esquerra, Raymond M., Zimmerman, Thomas, Capponi, Sara, Fung, Jennifer C. and Nystul, Todd G. (2024). A High-Throughput Method for Quantifying Drosophila Fecundity. Toxics, 12 (9), 658. doi: 10.3390/toxics12090658

A High-Throughput Method for Quantifying Drosophila Fecundity

2024

Journal Article

Sex differences in Huntington's disease from a neuroinflammation perspective

Risby-Jones, Grace, Lee, John D., Woodruff, Trent M. and Fung, Jenny N. (2024). Sex differences in Huntington's disease from a neuroinflammation perspective. Frontiers in Neurology, 15 1384480, 1-7. doi: 10.3389/fneur.2024.1384480

Sex differences in Huntington's disease from a neuroinflammation perspective

2024

Journal Article

Complement C5a receptor signaling alters stress responsiveness and modulates microglia following chronic stress exposure

Chen, Hsiao-Jou Cortina, Spiers, Jereme G., Lerskiatiphanich, Titaya, Parker, Sandra E., Lavidis, Nickolas A., Fung, Jenny N., Woodruff, Trent M. and Lee, John D. (2024). Complement C5a receptor signaling alters stress responsiveness and modulates microglia following chronic stress exposure. Biological Psychiatry: Global Open Science, 4 (3) 100306, 100306. doi: 10.1016/j.bpsgos.2024.100306

Complement C5a receptor signaling alters stress responsiveness and modulates microglia following chronic stress exposure

2024

Journal Article

Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing

Li, Xaria X., Fung, Jenny N., Clark, Richard J., Lee, John D. and Woodruff, Trent M. (2024). Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing. Proceedings of the National Academy of Sciences, 121 (5) e2314627121, 1-10. doi: 10.1073/pnas.2314627121

Cell-intrinsic C5a synergizes with Dectin-1 in macrophages to mediate fungal killing

2023

Journal Article

A molecular staging model for accurately dating the endometrial biopsy

Teh, W. T., Chung, J., Holdsworth-Carson, S. J., Donoghue, J. F., Healey, M., Rees, H. C., Bittinger, S., Obers, V., Sloggett, C., Kendarsari, R., Fung, J. N., Mortlock, S., Montgomery, G. W., Girling, J. E. and Rogers, P. A. W. (2023). A molecular staging model for accurately dating the endometrial biopsy. Nature Communications, 14 (1) 6222, 6222. doi: 10.1038/s41467-023-41979-z

A molecular staging model for accurately dating the endometrial biopsy

2023

Journal Article

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Rahmioglu, Nilufer, Mortlock, Sally, Ghiasi, Marzieh, Møller, Peter L., Stefansdottir, Lilja, Galarneau, Geneviève, Turman, Constance, Danning, Rebecca, Law, Matthew H., Sapkota, Yadav, Christofidou, Paraskevi, Skarp, Sini, Giri, Ayush, Banasik, Karina, Krassowski, Michal, Lepamets, Maarja, Marciniak, Błażej, Nõukas, Margit, Perro, Danielle, Sliz, Eeva, Sobalska-Kwapis, Marta, Thorleifsson, Gudmar, Topbas-Selcuki, Nura F., Vitonis, Allison, Westergaard, David, Arnadottir, Ragnheidur, Burgdorf, Kristoffer S., Campbell, Archie, Cheuk, Cecilia S. K. ... The 23andMe Research Team (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics, 55 (3), 423-436. doi: 10.1038/s41588-023-01323-z

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

2023

Journal Article

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

2022

Book Chapter

Neuroinflammation in Huntington’s

Lee, John D., Lo, Martin W., Fung, Jenny N. T. and Woodruff, Trent M. (2022). Neuroinflammation in Huntington’s. Neurodegenerative Diseases Biomarkers. (pp. 215-233) edited by Philip V. Peplow, Bridget Martinez and Thomas A. Gennarelli. New York, NY, United States: Springer US. doi: 10.1007/978-1-0716-1712-0_9

Neuroinflammation in Huntington’s

2021

Journal Article

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Lee, Han Siean, Rolfe, Barbara E., Woodruff, Trent M. and Clark, Richard J. (2021). Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity. Journal of Medicinal Chemistry, 64 (22) acs.jmedchem.1c01174, 16598-16608. doi: 10.1021/acs.jmedchem.1c01174

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

2021

Journal Article

Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism

McDonald, Tanya S., Kumar, Vinod, Fung, Jenny N., Woodruff, Trent M. and Lee, John D. (2021). Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism. The FASEB Journal, 35 (7) e21707, e21707. doi: 10.1096/fj.202002450r

Glucose clearance and uptake is increased in the SOD1 G93A mouse model of amyotrophic lateral sclerosis through an insulin‐independent mechanism

2021

Journal Article

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

Holdsworth-Carson, Sarah J., Churchill, Molly, Donoghue, Jacqueline F., Mortlock, Sally, Fung, Jenny N., Sloggett, Clare, Chung, Jessica, Cann, Leonie, Teh, Wan Tinn, Campbell, Katie-Rose, Luwor, Rodney, Healey, Martin, Montgomery, Grant, Girling, Jane E. and Rogers, Peter A. W. (2021). Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis. Molecular Human Reproduction, 27 (3) gaab010. doi: 10.1093/molehr/gaab010

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

2021

Journal Article

An immunoregulatory role for complement receptors in murine models of breast cancer

Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A., Manthey, Helga D., Sonderegger, Stefan E., Fung, Jenny Nga Ting, McGirr, Crystal E., Shiels, Ian A., Mills, Paul C., Woodruff, Trent M. and Rolfe, Barbara E. (2021). An immunoregulatory role for complement receptors in murine models of breast cancer. Antibodies, 10 (1) 2, 1-12. doi: 10.3390/antib10010002

An immunoregulatory role for complement receptors in murine models of breast cancer

2021

Journal Article

Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium

Marla, S., Mortlock, S., Houshdaran, S., Fung, J., McKinnon, B., Holdsworth-Carson, S. J., Girling, J. E., Rogers, P. A. W., Giudice, L. C. and Montgomery, G. W. (2021). Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium. Molecular Human Reproduction, 27 (1) gaaa082. doi: 10.1093/molehr/gaaa082

Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium

2020

Journal Article

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis

Lee, John D., McDonald, Tanya S., Fung, Jenny N. T. and Woodruff, Trent M. (2020). Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis. Molecular Neurobiology, 57 (10), 4143-4155. doi: 10.1007/s12035-020-02019-9

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis

2020

Journal Article

Tissue specific regulation of transcription in endometrium and association with disease

Mortlock, Sally, Kendarsari, Raden I., Fung, Jenny N., Gibson, Greg, Yang, Fei, Restuadi, Restuadi, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Lukowski, Samuel W., Healey, Martin, Qi, Ting, Rogers, Peter A. W., Yang, Jian, McKinnon, Brett and Montgomery, Grant W. (2020). Tissue specific regulation of transcription in endometrium and association with disease. Human Reproduction, 35 (2), 377-393. doi: 10.1093/humrep/dez279

Tissue specific regulation of transcription in endometrium and association with disease

2020

Journal Article

Obesity does not alter endometrial gene expression in women with endometriosis

Holdsworth-Carson, Sarah J, Chung, Jessica, Sloggett, Clare, Mortlock, Sally, Fung, Jenny N., Montgomery, Grant W., Dior, Uri P., Healey, Martin, Rogers, Peter A.W. and Girling, Jane E. (2020). Obesity does not alter endometrial gene expression in women with endometriosis. Reproductive BioMedicine Online, 41 (1), 113-118. doi: 10.1016/j.rbmo.2020.03.015

Obesity does not alter endometrial gene expression in women with endometriosis

2019

Journal Article

Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

Mortlock, Sally, Restuadi, Restuadi, Levien, Rupert, Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Zhu, Zhihong, Qi, Ting, Wu, Yang, Lukowski, Samuel W., Rogers, Peter A. W., Yang, Jian, McRae, Allan F., Fung, Jenny N. and Montgomery, Grant W. (2019). Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clinical Epigenetics, 11 (1) 49, 49. doi: 10.1186/s13148-019-0648-7

Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases

2019

Journal Article

Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes

Holdsworth-Carson, S. J., Colgrave, E. M., Donoghue, J. F., Fung, J. N., Churchill, M. L., Mortlock, S., Paiva, P., Healey, M., Montgomery, G. W., Girling, J. E. and Rogers, P. A. W. (2019). Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes. MHR: Basic science of reproductive medicine, 25 (4), 194-205. doi: 10.1093/molehr/gaz006

Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes

2019

Conference Publication

Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis

Holdsworth-Carson, Sarah J., Chung, Jessica, Healey, Martin, Fung, Jenny N., Montgomery, Grant, Rogers, Peter and Girling, Jane (2019). Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019 . Thousand Oaks, CA, United States: Sage.

Obesity Does Not Impact on Endometrial Gene Expression in Women with Endometriosis

2019

Conference Publication

Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes

Holdsworth-Carson, Sarah J., Donoghue, Jacqueline, Colgrave, Eliza, Fung, Jenny N., Churchill, Molly, Healey, Martin, Montgomery, Grant, Girling, Jane and Rogers, Peter (2019). Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes. 66th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.

Generation of Immortalized Human Endometrial Stromal Cell Lines with Different Endometriosis Risk Genotypes

Funding

Past funding

  • 2020 - 2021
    Investigating the therapeutic inhibition of CXCR2 as a disease modifying treatment for motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant

Supervision

Availability

Dr Jenny Fung is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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